{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":2,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":2,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"313f3bcba735","filters":{"venue":"Genome Instability & Disease"}},"results":[{"id":"W3186435257","doi":"10.1007/s42764-021-00047-w","title":"Structural insights into the role of DNA-PK as a master regulator in NHEJ","year":2021,"lang":"en","type":"review","venue":"Genome Instability & Disease","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health","keywords":"Ku70; Ku80; DNA-PKcs; Non-homologous end joining; DNA repair; Cell biology; Biology; DNA; V(D)J recombination; DNA repair protein XRCC4; Protein kinase A; Phosphorylation; Molecular biology; DNA-binding protein; Genetics; Nucleotide excision repair; Transcription factor; Gene","authors":[{"name":"Siyu Chen","is_ca":false},{"name":"James P. Lees‐Miller","is_ca":true},{"name":"Yuan He","is_ca":false},{"name":"Susan P. Lees‐Miller","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01469140234375227,"gpt":0.2641548205828271,"spread":0.2494634182390748,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002877133,0.0007041858,0.0006717767,0.001343851,0.0002007255,0.0005713013,0.0005810612,0.0006742139,0.001754456],"category_scores_gemma":[0.0003276367,0.000239956,0.000225776,0.001564835,0.0003322002,0.001089671,0.0005235371,0.001190869,0.001835629],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005779653,"about_ca_system_score_gemma":0.0006847153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007125499,"about_ca_topic_score_gemma":0.001037774,"domain_scores_codex":[0.9999249,0.00001032653,0.00001004,0.0000164898,0.00002855487,0.000009617313],"domain_scores_gemma":[0.9999118,0.00003348882,0.00001409955,0.000003973989,0.00002462265,0.00001203372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008824825,0.00005585981,0.0001312452,0.0140502,0.00005607036,0.0002411965,0.00007087573,0.0007178601,0.007586729,0.01083923,0.0328608,0.9333017],"study_design_scores_gemma":[0.000009363759,0.0000682732,0.0005771788,0.00122676,0.00003985091,0.0006252638,0.00002913442,0.00008528413,0.0008750173,0.002345337,0.9941067,0.00001185625],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001922639,0.9974987,0.0001682657,0.0002723242,0.0002089899,0.000002590306,0.00001678163,0.000008148254,0.0016319],"genre_scores_gemma":[0.000896594,0.9978198,0.0001795212,0.0001362734,0.0001313532,0.000003681085,0.00002803106,0.000001487242,0.0008032741],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001754456,"threshold_uncertainty_score":0.005869269,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3015673613","doi":"10.1007/s42764-020-00011-0","title":"ATM-deficient lung, prostate and pancreatic cancer cells are acutely sensitive to the combination of olaparib and the ATR inhibitor AZD6738","year":2020,"lang":"en","type":"article","venue":"Genome Instability & Disease","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Cumming School of Medicine, University of Calgary; Alberta Cancer Foundation; Cancer Research Society","keywords":"Olaparib; PARP inhibitor; Cancer research; Prostate cancer; Poly ADP ribose polymerase; Apoptosis; Pancreatic cancer; Lung cancer; Programmed cell death; Medicine; Cancer; Chemistry; Internal medicine; Polymerase; Biochemistry; DNA","authors":[{"name":"Nicholas Jette","is_ca":true},{"name":"Suraj Radhamani","is_ca":true},{"name":"Ruiqiong Ye","is_ca":true},{"name":"Yaping Yu","is_ca":true},{"name":"Greydon Arthur","is_ca":true},{"name":"Siddhartha Goutam","is_ca":true},{"name":"Tarek A. Bismar","is_ca":true},{"name":"Mehul Kumar","is_ca":true},{"name":"Pinaki Bose","is_ca":true},{"name":"Steven Yip","is_ca":true},{"name":"Michael Kolinsky","is_ca":false},{"name":"Susan P. Lees‐Miller","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01542149582609048,"gpt":0.262783157519449,"spread":0.2473616616933585,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009874238,0.0002485998,0.0004938655,0.0002552239,0.0001994659,0.0003412005,0.0002892496,0.0002567537,0.001802539],"category_scores_gemma":[0.0001114363,0.000157169,0.000283311,0.0003131438,0.0001497964,0.000166175,0.0002146277,0.0007764398,0.0004574459],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002202917,"about_ca_system_score_gemma":0.0002423987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009767509,"about_ca_topic_score_gemma":0.001555724,"domain_scores_codex":[0.999754,0.00004256473,0.00002813585,0.0000400065,0.00007937916,0.00005594371],"domain_scores_gemma":[0.9998773,0.00003131071,0.00002239537,0.00001837021,0.000009414593,0.00004120259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006651463,0.0002245306,0.0006833029,0.0000690598,0.00002386522,0.0003059212,0.00003775867,0.0002471014,0.9940565,0.000101808,0.000245052,0.003339987],"study_design_scores_gemma":[0.0000774016,0.002473602,0.009481942,0.000008969709,0.00003211337,0.001020286,0.00006471865,0.001439134,0.982303,0.00004307333,0.003047055,0.000008801757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924226,0.002645969,0.0009355826,0.0001221488,0.00007345359,0.00006821925,0.0008950425,0.0001225479,0.002714414],"genre_scores_gemma":[0.9940804,0.0007557794,0.001372654,0.00006635758,0.00001667104,0.0000574266,0.001372967,0.000014117,0.002263656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001802539,"threshold_uncertainty_score":0.006030083,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}