{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":432,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":432,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"9c20802c01af","filters":{"venue":"Journal of Controlled Release"}},"results":[{"id":"W2057632167","doi":"10.1016/j.jconrel.2005.09.034","title":"Block copolymer micelles: preparation, characterization and application in drug delivery","year":2005,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Advanced Polymer Synthesis and Characterization","field":"Chemistry","cited_by":1478,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Micelle; Copolymer; Amphiphile; Drug delivery; Chemistry; Drug carrier; Targeted drug delivery; Aqueous solution; Materials science; Nanotechnology; Chemical engineering; Combinatorial chemistry; Organic chemistry; Polymer","authors":[{"name":"Geneviève Gaucher","is_ca":false},{"name":"Marie-Hélène Dufresne","is_ca":true},{"name":"Vinayak Sant","is_ca":true},{"name":"Ning Kang","is_ca":true},{"name":"Dušica Maysinger","is_ca":true},{"name":"Jean‐Christophe Leroux","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.007577565800516989,"gpt":0.2684377195213272,"spread":0.2608601537208102,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007163221,0.0009868433,0.00118904,0.001409539,0.0002213987,0.00059355,0.000971386,0.0009096899,0.00106516],"category_scores_gemma":[0.0004547154,0.0006050483,0.0002927805,0.001217921,0.0004327426,0.001245814,0.0003274219,0.000977573,0.001441291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005291581,"about_ca_system_score_gemma":0.0004772946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005076656,"about_ca_topic_score_gemma":0.001049128,"domain_scores_codex":[0.9997689,0.00002328898,0.00002717527,0.00004163072,0.0001117508,0.00002721656],"domain_scores_gemma":[0.9997846,0.0000645547,0.00004462826,0.00001366162,0.00007736441,0.00001518345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001659341,0.0002569888,0.0001562849,0.004555165,0.00005927625,0.0003184779,0.0000660583,0.0008640743,0.2335437,0.002538432,0.006342479,0.7511331],"study_design_scores_gemma":[0.00006099523,0.0006592029,0.001528656,0.0005126981,0.0001619793,0.004403962,0.00004265238,0.00165689,0.3191013,0.00123183,0.6705697,0.00007008287],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004793642,0.982734,0.008877511,0.0002292066,0.0004176147,0.00004782337,0.00004777492,0.00007201273,0.002780411],"genre_scores_gemma":[0.02122176,0.9601406,0.009714588,0.0002733475,0.0003685427,0.00007649098,0.0001218607,0.00002157317,0.008061226],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001409539,"threshold_uncertainty_score":0.003839314,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1985631236","doi":"10.1016/s0168-3659(02)00009-3","title":"Pluronic® block copolymers as novel polymer therapeutics for drug and gene delivery","year":2002,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":1443,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Supratek Pharma (Canada)","funders":"","keywords":"Poloxamer; Chemistry; Bioavailability; Drug; Drug delivery; Efflux; Micelle; Copolymer; Gene delivery; Pharmacology; Polymer; Biochemistry; Organic chemistry; Transfection; Gene; Medicine; Aqueous solution","authors":[{"name":"Alexander V. Kabanov","is_ca":false},{"name":"Elena V. Batrakova","is_ca":false},{"name":"Valery Yu. Alakhov","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02674529855680473,"gpt":0.2821518058171755,"spread":0.2554065072603707,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005090621,0.0009093765,0.0008124835,0.001084076,0.0002031636,0.0005935344,0.0006522528,0.0008339567,0.001308743],"category_scores_gemma":[0.0002453575,0.0003952557,0.0002508685,0.0009132865,0.0004209338,0.001160516,0.0003465407,0.0008054134,0.001358765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005288979,"about_ca_system_score_gemma":0.0004417584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005910038,"about_ca_topic_score_gemma":0.001110588,"domain_scores_codex":[0.9998404,0.00002157725,0.00002155384,0.0000257125,0.00006929892,0.00002148382],"domain_scores_gemma":[0.999913,0.00002984913,0.00002111358,0.000005329337,0.00002204403,0.000008653586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002076005,0.0001677864,0.00008708378,0.004072353,0.00004441734,0.000494663,0.00009795996,0.001079558,0.2480261,0.007057108,0.00472921,0.7339362],"study_design_scores_gemma":[0.00006981791,0.0006747288,0.0006320364,0.0003685542,0.0001288792,0.003237021,0.00004161808,0.001388516,0.2635751,0.001263598,0.7285627,0.00005737881],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01013329,0.9741657,0.008823922,0.0002595204,0.0006126739,0.00005529757,0.00005041677,0.00009575745,0.005803496],"genre_scores_gemma":[0.04155284,0.9295186,0.00905966,0.0003168718,0.0004767467,0.00009903016,0.0001708717,0.00002961333,0.0187757],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001308743,"threshold_uncertainty_score":0.00437814,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2233414233","doi":"10.1016/j.jconrel.2016.01.020","title":"Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination","year":2016,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":1327,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University Health Network; Toronto Rehabilitation Institute; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto; Prostate Cancer Canada","keywords":"Nanoparticle; Liver cancer; Translation (biology); Toxicity; Chemistry; Cancer; Medicine; Pharmacology; Nanotechnology; Cancer research; Internal medicine; Biochemistry; Materials science","authors":[{"name":"Yi-Nan Zhang","is_ca":true},{"name":"Wilson Poon","is_ca":true},{"name":"Anthony J. Tavares","is_ca":true},{"name":"Ian D. McGilvray","is_ca":true},{"name":"Warren C. W. Chan","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02050370679377632,"gpt":0.2789454241771442,"spread":0.2584417173833679,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004177452,0.0009700477,0.001056059,0.001144693,0.000181348,0.000718268,0.0006217741,0.001061508,0.0013122],"category_scores_gemma":[0.0003273271,0.0003590711,0.0003892453,0.0008878172,0.0004766351,0.0007936399,0.0004734409,0.0009938887,0.000968112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004371506,"about_ca_system_score_gemma":0.0004714855,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005738807,"about_ca_topic_score_gemma":0.001020342,"domain_scores_codex":[0.9998339,0.00002284145,0.00001926805,0.00003344006,0.00006805814,0.00002243395],"domain_scores_gemma":[0.9998628,0.00005835535,0.00003306732,0.000005289585,0.00003192049,0.000008532844],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001869842,0.0001699182,0.0001778784,0.0162124,0.00009023885,0.0004810832,0.0001021912,0.0008252917,0.07118961,0.005191154,0.009962607,0.8954107],"study_design_scores_gemma":[0.00003737747,0.000436256,0.001271576,0.001786875,0.0002135901,0.00452772,0.00008554459,0.001019002,0.07230439,0.001723413,0.9165334,0.00006084589],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001277908,0.9950261,0.001324125,0.0001762037,0.0002421177,0.00001306069,0.00001546452,0.00001613815,0.001908861],"genre_scores_gemma":[0.01103557,0.9830537,0.001579539,0.0001748986,0.0002346794,0.00002905665,0.00002914785,0.000006846662,0.003856486],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0013122,"threshold_uncertainty_score":0.004389763,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1420726270","doi":"10.1016/j.jconrel.2015.08.007","title":"Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes","year":2015,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1027,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"National Institute of Allergy and Infectious Diseases; Bill and Melinda Gates Foundation","keywords":"Kinetics; Nucleoside; Chemistry; Messenger RNA; Nanoparticle; Biochemistry; Nanotechnology; Materials science; Gene; Physics","authors":[{"name":"Norbert Pardi","is_ca":false},{"name":"Steven Tuyishime","is_ca":false},{"name":"Hiromi Muramatsu","is_ca":false},{"name":"Katalin Karikó","is_ca":false},{"name":"Barbara L. Mui","is_ca":true},{"name":"Ying K. Tam","is_ca":true},{"name":"Thomas D. Madden","is_ca":true},{"name":"Michael J. Hope","is_ca":true},{"name":"Drew Weissman","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01084181240632572,"gpt":0.2468475085053783,"spread":0.2360056960990526,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003336393,0.0003231751,0.000239426,0.0002014022,0.0001065993,0.0003787756,0.0002252814,0.0003164583,0.0007659055],"category_scores_gemma":[0.0003236574,0.0001613223,0.0002551755,0.0001454418,0.0003082158,0.000333248,0.00009521223,0.0004919525,0.0003253905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004391454,"about_ca_system_score_gemma":0.0002528727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008736498,"about_ca_topic_score_gemma":0.0007481146,"domain_scores_codex":[0.9998552,0.00002464198,0.00001108722,0.00003905166,0.00002653005,0.00004341542],"domain_scores_gemma":[0.9997813,0.00006785837,0.00006499176,0.00001245883,0.00004595615,0.00002746081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003467415,0.00001465719,0.00009302385,0.00002507997,0.000003668881,0.00002177596,0.00003103273,0.0001636095,0.9982737,0.0001569723,0.00002218778,0.0008474621],"study_design_scores_gemma":[0.000006410974,0.0001465409,0.0002147854,0.000001777569,0.00001080146,0.00001292232,0.000006050393,0.0006703989,0.9986822,0.00001959303,0.0002251475,0.000003309794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910322,0.000921988,0.005991351,0.00006076614,0.00002802605,0.00003256969,0.000261451,0.0001048548,0.001566779],"genre_scores_gemma":[0.988215,0.000891014,0.004914332,0.00004590303,0.0000139535,0.00005620383,0.0003159927,0.00009040236,0.005457242],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008736498,"threshold_uncertainty_score":0.003186285,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1963675633","doi":"10.1016/j.jconrel.2013.09.013","title":"Factors controlling the pharmacokinetics, biodistribution and intratumoral penetration of nanoparticles","year":2013,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":986,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University Health Network; Toronto Metropolitan University; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research; National Institutes of Health; Ontario Centres of Excellence; National Cancer Institute; Prostate Cancer Foundation","keywords":"Biodistribution; Pharmacokinetics; PEGylation; Bioavailability; Drug delivery; Tumor microenvironment; Chemistry; Nanoparticle; Nanomedicine; Pharmacology; Drug carrier; Stroma; Biophysics; Cancer research; Medicine; Nanotechnology; Pathology; Materials science; Tumor cells; In vitro; Biochemistry; Biology","authors":[{"name":"Mark J. Ernsting","is_ca":true},{"name":"Mami Murakami","is_ca":true},{"name":"Aniruddha Roy","is_ca":true},{"name":"Shyh‐Dar Li","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03795342977861244,"gpt":0.2960749492036895,"spread":0.2581215194250771,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000396247,0.0007644085,0.0008892124,0.0006429064,0.0001500427,0.0007205521,0.0005425042,0.0006811318,0.0006644261],"category_scores_gemma":[0.0003492882,0.0003311394,0.0002978499,0.000645671,0.0004681799,0.0007817172,0.0002900555,0.0007241029,0.0004382143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005400852,"about_ca_system_score_gemma":0.0006249213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008945684,"about_ca_topic_score_gemma":0.00118179,"domain_scores_codex":[0.9998441,0.00001786805,0.00001554477,0.00003519042,0.00006082512,0.00002651137],"domain_scores_gemma":[0.9998529,0.00006945316,0.00003557999,0.000004909882,0.0000309887,0.000006089283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002109108,0.0001479944,0.000537045,0.01037357,0.00007813797,0.0003964189,0.00008245164,0.001269224,0.2606004,0.004183201,0.003815843,0.7183048],"study_design_scores_gemma":[0.00006297131,0.0006906084,0.007365808,0.001828408,0.000405694,0.005010859,0.0001590761,0.001884653,0.3386637,0.003531808,0.6402871,0.0001092932],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005087037,0.991476,0.001468528,0.0002201247,0.0001009964,0.00001982978,0.00002893422,0.00001399103,0.001584499],"genre_scores_gemma":[0.02040062,0.9763841,0.001182297,0.0001256022,0.0001080566,0.00002740404,0.00004885844,0.000004983964,0.001718056],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0008945684,"threshold_uncertainty_score":0.003918648,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2002667018","doi":"10.1016/j.jconrel.2014.02.020","title":"Review on materials & methods to produce controlled release coated urea fertilizer","year":2014,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Polymer-Based Agricultural Enhancements","field":"Engineering","cited_by":937,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Universiti Teknologi Petronas; University of British Columbia","keywords":"Urea; Leaching (pedology); Fertilizer; Volatilisation; Environmental science; Coated urea; Agriculture; Coating; Population; Environmental pollution; Nitrogen; Pollution; Chemistry; Environmental protection; Materials science; Nanotechnology; Soil science; Soil water; Biology; Ecology; Biochemistry","authors":[{"name":"Babar Azeem","is_ca":false},{"name":"KuZilati KuShaari","is_ca":false},{"name":"Zakaria Man","is_ca":false},{"name":"Abdul Basit","is_ca":false},{"name":"Thanh H. Trinh","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03290808880154542,"gpt":0.3563311113407121,"spread":0.3234230225391667,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000315757,0.0008971235,0.0007624305,0.001746064,0.0002190311,0.0006147986,0.0006465356,0.0006280955,0.004019545],"category_scores_gemma":[0.000416082,0.000377083,0.0003752193,0.001682383,0.0002615656,0.0008947609,0.0003963371,0.001008486,0.002633881],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003130716,"about_ca_system_score_gemma":0.0007550792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006689073,"about_ca_topic_score_gemma":0.001554741,"domain_scores_codex":[0.9998289,0.00001412064,0.00001847875,0.00003179975,0.00009186177,0.0000147682],"domain_scores_gemma":[0.9998273,0.0000730394,0.00004323032,0.000006470497,0.00003912416,0.00001079835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000567532,0.0001354616,0.00008309395,0.02645901,0.00007824363,0.0002681707,0.00005639769,0.0004883954,0.03445283,0.004808924,0.03334942,0.8997633],"study_design_scores_gemma":[0.0000110794,0.0001266325,0.000413818,0.001542834,0.00006893346,0.0005995137,0.00002274451,0.0001387236,0.01003816,0.0006098497,0.9864043,0.0000235148],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009339826,0.9883121,0.002134464,0.0002386068,0.0008208609,0.00004979996,0.0001148998,0.000039828,0.007355512],"genre_scores_gemma":[0.002950858,0.9872935,0.002319978,0.0002967109,0.0002208552,0.00004329864,0.000087297,0.00001045442,0.006777086],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004019545,"threshold_uncertainty_score":0.01344675,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2020535635","doi":"10.1016/j.jconrel.2012.12.013","title":"Biocompatibility of engineered nanoparticles for drug delivery","year":2012,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":796,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"","keywords":"Biocompatibility; Drug delivery; Nanotechnology; Nanoparticle; Computer science; Materials science","authors":[{"name":"Sheva Naahidi","is_ca":true},{"name":"Mousa Jafari","is_ca":true},{"name":"Faramarz Edalat","is_ca":false},{"name":"Kevin P. Raymond","is_ca":true},{"name":"Ali Khademhosseini","is_ca":false},{"name":"P. Chen","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02989300094309277,"gpt":0.2857073976664388,"spread":0.255814396723346,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005631018,0.0009951182,0.001006028,0.001019101,0.0001661438,0.000656619,0.0009352957,0.001084007,0.000854666],"category_scores_gemma":[0.0003647091,0.0004394297,0.0004180924,0.0008711918,0.0005053963,0.0008250661,0.0005128928,0.0009761903,0.0009223528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007238097,"about_ca_system_score_gemma":0.0003500548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000653986,"about_ca_topic_score_gemma":0.0008432998,"domain_scores_codex":[0.9997669,0.00002698658,0.00002325515,0.00004781609,0.0001054571,0.00002964371],"domain_scores_gemma":[0.999854,0.00005538593,0.0000344962,0.000009625862,0.00003933133,0.000007175936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001445579,0.000191271,0.000130472,0.01059561,0.00009586403,0.0004912768,0.00009511002,0.001560881,0.3331724,0.005399381,0.006554489,0.6415687],"study_design_scores_gemma":[0.000052185,0.0004886091,0.001552714,0.001348358,0.0002112346,0.002873141,0.00005319868,0.002041451,0.319452,0.002064162,0.6697794,0.00008356041],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005238397,0.987002,0.00364357,0.0002191662,0.0003376328,0.00003448694,0.00003154795,0.00003330551,0.003459837],"genre_scores_gemma":[0.03447221,0.9521302,0.004794199,0.0003631377,0.0002437806,0.00006619345,0.00009729538,0.00002590977,0.007807053],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001084007,"threshold_uncertainty_score":0.005251646,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1998935458","doi":"10.1016/j.jconrel.2007.09.014","title":"Organogels and their use in drug delivery — A review","year":2007,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Supramolecular Self-Assembly in Materials","field":"Materials Science","cited_by":728,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"","keywords":"Transdermal; Drug delivery; Nanotechnology; Phase (matter); Materials science; Computer science; Biochemical engineering; Chemistry; Organic chemistry; Medicine; Pharmacology; Engineering","authors":[{"name":"Anda Vintiloìu","is_ca":true},{"name":"Jean‐Christophe Leroux","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03288295702772832,"gpt":0.3098367762778036,"spread":0.2769538192500753,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000440437,0.0009607939,0.001206516,0.001701975,0.0002749822,0.0008364963,0.0008744677,0.0008719845,0.002101018],"category_scores_gemma":[0.0003728027,0.0003527977,0.0003443647,0.001768873,0.0005638048,0.001200529,0.0005252421,0.001005531,0.001482323],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003917806,"about_ca_system_score_gemma":0.000664026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006062132,"about_ca_topic_score_gemma":0.001327334,"domain_scores_codex":[0.9998641,0.00001480792,0.0000175408,0.00002710104,0.00006096002,0.00001553408],"domain_scores_gemma":[0.999841,0.00006999511,0.00003261289,0.000005994663,0.00003634822,0.00001394382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001151453,0.0001786277,0.0001345112,0.01318737,0.0001142949,0.0003205452,0.00006461043,0.0007099991,0.01873383,0.005048959,0.01793429,0.9434579],"study_design_scores_gemma":[0.0000302319,0.0001976901,0.0004662832,0.001344929,0.0001186424,0.001376444,0.00004742603,0.0002829113,0.007913544,0.001227461,0.9869637,0.00003070468],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003914289,0.9973488,0.0005942159,0.0001112675,0.0003089703,0.000009637302,0.00001339812,0.0000112584,0.001210948],"genre_scores_gemma":[0.001936793,0.9959071,0.0006664332,0.0001000359,0.0002125949,0.00001416195,0.00002125372,0.000002329531,0.001139414],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002101018,"threshold_uncertainty_score":0.00702858,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1974371653","doi":"10.1016/s0168-3659(02)00008-1","title":"Biodegradable injectable in situ forming drug delivery systems","year":2002,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":727,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Queen's University; University of Alberta","funders":"","keywords":"Drug delivery; Drug; Nanotechnology; In situ; Materials science; Computer science; Chemistry; Medicine; Pharmacology; Organic chemistry","authors":[{"name":"Arash Hatefi","is_ca":true},{"name":"Brian G. Amsden","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09435128247444799,"gpt":0.4012596407318517,"spread":0.3069083582574037,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002324666,0.0007934432,0.0008675403,0.0009309164,0.0001542511,0.0005000295,0.0006908259,0.0004836828,0.002090305],"category_scores_gemma":[0.0001658129,0.0002647934,0.0002630155,0.0007780671,0.0003123965,0.000767356,0.000264971,0.0006572943,0.001208549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003422471,"about_ca_system_score_gemma":0.000210519,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00031868,"about_ca_topic_score_gemma":0.0005824943,"domain_scores_codex":[0.9998676,0.00001156419,0.00001196228,0.00002686045,0.000066532,0.00001561568],"domain_scores_gemma":[0.9999123,0.00002480883,0.0000353997,0.00000483238,0.00001569581,0.000006964336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001272208,0.0002115643,0.0001093629,0.003681087,0.00003090837,0.000421972,0.00008472613,0.0006992634,0.3274804,0.002946048,0.002470253,0.6617372],"study_design_scores_gemma":[0.00006012052,0.0009723414,0.001617001,0.0005703646,0.0001577711,0.004666718,0.00006808793,0.001442753,0.3380228,0.0009762108,0.6513773,0.00006847689],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02140636,0.9334357,0.0304363,0.0002570979,0.000695473,0.0001115133,0.0001524438,0.0003384738,0.01316672],"genre_scores_gemma":[0.07540181,0.8611884,0.0229574,0.0003581556,0.0003863375,0.0001147576,0.0002621937,0.00005634812,0.03927458],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002090305,"threshold_uncertainty_score":0.006992757,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2033857478","doi":"10.1016/j.jconrel.2011.09.098","title":"The journey of a drug-carrier in the body: An anatomo-physiological perspective","year":2011,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":694,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"Centers for Disease Control and Prevention; Canada Research Chairs; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Biodistribution; Drug delivery; Nanotechnology; Perspective (graphical); Drug carrier; Engineering ethics; Medicine; Risk analysis (engineering); Management science; Computer science; Engineering; Materials science; Biology; Biotechnology; Artificial intelligence","authors":[{"name":"Nicolas Bertrand","is_ca":true},{"name":"Jean‐Christophe Leroux","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03447074710322676,"gpt":0.3193328968079268,"spread":0.2848621497047,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010076,0.001257762,0.002000465,0.002080089,0.0006493581,0.002369588,0.001561663,0.003209624,0.002355024],"category_scores_gemma":[0.0006076113,0.0004356563,0.0005740063,0.001832106,0.00209834,0.0044185,0.001121653,0.003195703,0.001923816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001371356,"about_ca_system_score_gemma":0.001590493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001117075,"about_ca_topic_score_gemma":0.002087417,"domain_scores_codex":[0.9997476,0.00004752037,0.00002817003,0.00005417977,0.00008508422,0.00003745536],"domain_scores_gemma":[0.9996784,0.0001608387,0.00003546552,0.00001113761,0.00007759373,0.00003652702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001754403,0.0002395719,0.0003063859,0.02136889,0.00007446348,0.001213221,0.0003801864,0.0009356538,0.02125014,0.04620581,0.02935738,0.8784929],"study_design_scores_gemma":[0.00001226593,0.0001824233,0.000409589,0.002576029,0.00005443383,0.003310146,0.0002445308,0.0002734265,0.003433239,0.006674542,0.982786,0.00004339028],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001485645,0.9976218,0.0004285839,0.0007197364,0.000296284,0.0000029855,0.000006057512,0.000005718997,0.0007702507],"genre_scores_gemma":[0.001374518,0.9965886,0.0006232023,0.0003150841,0.0002608266,0.000006035659,0.000008489804,0.000002333705,0.0008209146],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003209624,"threshold_uncertainty_score":0.009949923,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1979146520","doi":"10.1016/j.jconrel.2003.09.013","title":"An overview of current delivery systems in cancer gene therapy","year":2003,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":690,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Genetic enhancement; Gene delivery; Viral vector; Cationic liposome; Biology; Vectors in gene therapy; Retrovirus; Immunogenicity; Oncolytic virus; Computational biology; Vector (molecular biology); Transgene; Virology; Gene; Virus; Genetics; Recombinant DNA; Immune system","authors":[{"name":"Anas El‐Aneed","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09789173012628456,"gpt":0.3992349048140575,"spread":0.3013431746877729,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009338377,0.001302595,0.002314701,0.002783921,0.0005916424,0.001463513,0.001791876,0.001661711,0.003135922],"category_scores_gemma":[0.000537635,0.0006777854,0.0007242675,0.002727214,0.0007536889,0.001932881,0.0006127639,0.002170478,0.003054203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000933791,"about_ca_system_score_gemma":0.0008026724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009500834,"about_ca_topic_score_gemma":0.001732428,"domain_scores_codex":[0.9996943,0.00004221812,0.00003684775,0.00005043305,0.0001454531,0.00003072415],"domain_scores_gemma":[0.9997297,0.0001499744,0.0000335955,0.00001063743,0.00005518725,0.00002087138],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000153596,0.0002397608,0.0001072015,0.0131265,0.00006536568,0.0004480215,0.00009958669,0.0008841004,0.02640198,0.006196864,0.02113916,0.9311379],"study_design_scores_gemma":[0.00004643661,0.0002924334,0.0005077938,0.00134763,0.0001052316,0.002462485,0.00005253173,0.0004335224,0.008749471,0.002009939,0.9839506,0.00004195119],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003309697,0.994289,0.002830478,0.0001581581,0.0003327757,0.00002475382,0.00002556122,0.00004184506,0.001966439],"genre_scores_gemma":[0.001441223,0.9924839,0.003433136,0.0001779645,0.0002250341,0.00004700858,0.00005403816,0.000008024553,0.002129681],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003135922,"threshold_uncertainty_score":0.01049072,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1977467418","doi":"10.1016/j.jconrel.2014.06.046","title":"PEG — A versatile conjugating ligand for drugs and drug delivery systems","year":2014,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":631,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Indian Council of Medical Research; Foreign Affairs and International Trade Canada; Canadian Bureau for International Education","keywords":"PEGylation; PEG ratio; Drug delivery; Polyethylene glycol; Pharmacology; Pharmacokinetics; Immunogenicity; Drug; Chemistry; Combinatorial chemistry; Medicine; Biochemistry; Immune system; Immunology; Business; Organic chemistry","authors":[{"name":"Atul Kolate","is_ca":false},{"name":"Dipesh Baradia","is_ca":false},{"name":"Sushilkumar Patil","is_ca":false},{"name":"Imran Vhora","is_ca":false},{"name":"Girish Kore","is_ca":false},{"name":"Ambikanandan Misra","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01429648234618061,"gpt":0.2696428056344586,"spread":0.255346323288278,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003129316,0.0007562285,0.000549765,0.001186264,0.0001738577,0.0004856373,0.0005913746,0.0006757807,0.0009987749],"category_scores_gemma":[0.0001872887,0.0002909245,0.0002393808,0.0009657696,0.0003709575,0.000841024,0.0005671394,0.001035937,0.001185594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005685377,"about_ca_system_score_gemma":0.0004270182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006367802,"about_ca_topic_score_gemma":0.0009071736,"domain_scores_codex":[0.9998623,0.00001407357,0.00001441492,0.00002851091,0.00006089483,0.00001973906],"domain_scores_gemma":[0.9999305,0.00001786894,0.00001966709,0.00000488112,0.00001897318,0.000008141615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006944528,0.0001162237,0.000115533,0.004480411,0.00005275767,0.0003623682,0.0000523465,0.0008817877,0.132736,0.008031894,0.0113391,0.8417622],"study_design_scores_gemma":[0.00001358689,0.0001577474,0.0004933459,0.0004460358,0.00006162483,0.001786695,0.00002196714,0.0007540249,0.0872992,0.001269371,0.907664,0.00003245617],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004988429,0.9728934,0.01086084,0.0006247048,0.0007074612,0.00005050742,0.00007744496,0.0001185228,0.009678756],"genre_scores_gemma":[0.03016533,0.9435342,0.008789703,0.0006257627,0.0005050646,0.00006565863,0.0001586426,0.00002586208,0.01612977],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001186264,"threshold_uncertainty_score":0.004125059,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2223591983","doi":"10.1016/j.jconrel.2016.01.009","title":"PEGylated and targeted extracellular vesicles display enhanced cell specificity and circulation time","year":2016,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":613,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"European Research Council; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; European Commission","keywords":"PEG ratio; Chemistry; PEGylation; Biophysics; Drug delivery; Polyethylene glycol; Micelle; Conjugated system; Cell biology; Biochemistry; Biology","authors":[{"name":"Sander A. A. Kooijmans","is_ca":false},{"name":"Lies A. L. Fliervoet","is_ca":false},{"name":"Roy van der Meel","is_ca":true},{"name":"Marcel H.A.M. Fens","is_ca":false},{"name":"Harry F.G. Heijnen","is_ca":false},{"name":"Paul M.P. van Bergen en Henegouwen","is_ca":false},{"name":"Pieter Vader","is_ca":false},{"name":"Raymond M. Schiffelers","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.003404808061198768,"gpt":0.2015898097524716,"spread":0.1981850016912729,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002010481,0.0002727128,0.0002598847,0.0001139714,0.00009220115,0.0005414883,0.0002177686,0.0005629151,0.0006547974],"category_scores_gemma":[0.0002386916,0.0001923076,0.0002228583,0.0001418807,0.0001818611,0.0005782144,0.0002454804,0.00039745,0.0002433403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003597248,"about_ca_system_score_gemma":0.0001503582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003635733,"about_ca_topic_score_gemma":0.0003477313,"domain_scores_codex":[0.9998827,0.00001717993,0.000008030019,0.00003161806,0.00002213618,0.00003832939],"domain_scores_gemma":[0.9998755,0.00003275051,0.00003664596,0.00001268958,0.00002070754,0.00002162803],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001258458,0.000008615712,0.00004474296,0.00001144767,0.000002741008,0.00003132138,0.00001518628,0.00009267253,0.9982768,0.0002664344,0.00001791439,0.001106299],"study_design_scores_gemma":[0.00001347765,0.00008417833,0.0004147049,0.000001510988,0.000009284769,0.00008799428,0.000005427815,0.0007673047,0.9977805,0.00004682071,0.000784821,0.000004064943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886078,0.001548594,0.008448517,0.00007724878,0.00002868667,0.00001915489,0.0000956132,0.00007592607,0.00109853],"genre_scores_gemma":[0.9946433,0.0003769996,0.002427128,0.00004321388,0.000007598559,0.00001357688,0.00008896175,0.00003450098,0.002364769],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006547974,"threshold_uncertainty_score":0.002610028,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2086919915","doi":"10.1016/j.jconrel.2005.06.014","title":"Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids","year":2005,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":564,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"University of British Columbia","keywords":"Nucleic acid; Endosome; Cationic polymerization; Chemistry; Biophysics; Intracellular; Transfection; Biochemistry; Biology; Organic chemistry; Gene","authors":[{"name":"James Heyes","is_ca":false},{"name":"Lorne Palmer","is_ca":false},{"name":"K. Helen Bremner","is_ca":false},{"name":"Ian MacLachlan","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005477606288132852,"gpt":0.2263686813326451,"spread":0.2208910750445122,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003711202,0.000262504,0.0002512821,0.0001322069,0.0001740791,0.0005436987,0.0002406142,0.0003039408,0.001286819],"category_scores_gemma":[0.0007602065,0.0002352607,0.0001248373,0.0001570005,0.0004363296,0.0004651517,0.0002814243,0.0003903349,0.0002677622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005549362,"about_ca_system_score_gemma":0.0003541023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00120553,"about_ca_topic_score_gemma":0.001154218,"domain_scores_codex":[0.9997823,0.00004226953,0.00001849037,0.00003938398,0.00004069094,0.00007696242],"domain_scores_gemma":[0.9994928,0.0002715144,0.00008831804,0.00002421126,0.00005794005,0.00006524577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002208645,0.00000949676,0.00005337078,0.00001590488,0.000002261388,0.00002587336,0.00002515274,0.00005581428,0.9991298,0.00007515225,0.000009000282,0.0003773232],"study_design_scores_gemma":[0.00001071749,0.00008309157,0.0002342766,0.000001454183,0.000005623799,0.00001723044,0.000009285899,0.0005955747,0.9988827,0.00001241011,0.0001451299,0.000002514073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978801,0.0002536605,0.0009663509,0.00003170063,0.000008176105,0.00001025397,0.00003691684,0.00001996495,0.000792791],"genre_scores_gemma":[0.9985973,0.0001346335,0.0004513295,0.00001554017,0.000002984426,0.000006772706,0.00003904995,0.0000216513,0.0007307788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001286819,"threshold_uncertainty_score":0.004304767,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2086393160","doi":"10.1016/j.jconrel.2010.03.016","title":"Stealth nanoparticles: High density but sheddable PEG is a key for tumor targeting","year":2010,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":553,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Cancer Institute","keywords":"Nanocarriers; RNA interference; Small interfering RNA; Gene silencing; Endosome; Cancer; Chemistry; RNA; Cancer research; Medicine; Pharmacology; Nanotechnology; Cell; Drug; Gene; Materials science; Biochemistry","authors":[{"name":"Shyh‐Dar Li","is_ca":true},{"name":"Leaf Huang","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.007077778899506636,"gpt":0.2322364741602657,"spread":0.225158695260759,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002402023,0.000314065,0.0001967116,0.0001212394,0.0001308506,0.0002524687,0.0001989485,0.0004699534,0.0009425298],"category_scores_gemma":[0.0002134577,0.0001841889,0.0001531442,0.00007430872,0.0002908416,0.000493966,0.0003709921,0.0005242709,0.0004861091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002500227,"about_ca_system_score_gemma":0.0001725772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001196361,"about_ca_topic_score_gemma":0.0001508498,"domain_scores_codex":[0.9999084,0.00001509631,0.000007706274,0.00002426692,0.00002791508,0.00001652604],"domain_scores_gemma":[0.9998883,0.00002195872,0.00002725826,0.00001969077,0.00001795565,0.00002469017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008449103,0.00001450845,0.00006949202,0.00003283663,0.00000450232,0.00004629007,0.00001830458,0.00009747858,0.994395,0.0005561389,0.0001584399,0.004522527],"study_design_scores_gemma":[0.000008706232,0.00008623717,0.0001804998,0.000002376237,0.000005235182,0.0001849287,0.00000413801,0.000522993,0.9962028,0.0001106108,0.002688651,0.000002909622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9305156,0.003809193,0.05542581,0.001277349,0.0001479283,0.0001232601,0.0002965984,0.0004846303,0.007919567],"genre_scores_gemma":[0.9838001,0.0009903418,0.009922624,0.000222884,0.00002821552,0.00002960931,0.0002070789,0.00006914612,0.004729965],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009425298,"threshold_uncertainty_score":0.003153086,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3048944217","doi":"10.1016/j.jconrel.2020.08.012","title":"Controlled anti-cancer drug release through advanced nano-drug delivery systems: Static and dynamic targeting strategies","year":2020,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":501,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"","keywords":"Drug delivery; Nanomedicine; Drug; Targeted drug delivery; Medicine; Pharmacology; Cancer; Nanotechnology; Nanoparticle; Materials science; Internal medicine","authors":[{"name":"Farshad Moradi Kashkooli","is_ca":true},{"name":"M. Soltani","is_ca":true},{"name":"Mohammad Souri","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01202276202983236,"gpt":0.285471876023048,"spread":0.2734491139932156,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004277227,0.0005908715,0.0007765245,0.001244187,0.0001785787,0.0006321643,0.0005077931,0.0007617863,0.000824005],"category_scores_gemma":[0.0001868469,0.0003075691,0.0004027433,0.0007140032,0.0004221739,0.0009438567,0.0004597183,0.0008721872,0.0006321836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004686065,"about_ca_system_score_gemma":0.0004150004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004948402,"about_ca_topic_score_gemma":0.0006613129,"domain_scores_codex":[0.9998432,0.00002376992,0.000009955666,0.00002823244,0.0000731724,0.00002159452],"domain_scores_gemma":[0.9999384,0.00002164775,0.0000145952,0.000003658204,0.00001617626,0.000005531061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007693969,0.0001996467,0.0001701697,0.01199303,0.00007962692,0.0003123251,0.0001542307,0.002365672,0.1386191,0.02429848,0.00504706,0.8166837],"study_design_scores_gemma":[0.00004182879,0.0007714772,0.001514628,0.001773918,0.0001546965,0.002623168,0.0001164322,0.005293858,0.1126322,0.004706913,0.8702759,0.00009487653],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003960907,0.988703,0.003997833,0.0003086606,0.0001584573,0.00002555249,0.00001378202,0.00002484022,0.00280685],"genre_scores_gemma":[0.02732347,0.9649333,0.00465655,0.0002094747,0.0001536044,0.00005218989,0.00002486254,0.000007918448,0.002638578],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001244187,"threshold_uncertainty_score":0.003400028,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2417973730","doi":"10.1016/j.jconrel.2016.06.012","title":"Nanomedicine of synergistic drug combinations for cancer therapy – Strategies and perspectives","year":2016,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":372,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"National Cancer Institute; National Institutes of Health; University of Toronto; Canadian Cancer Society","keywords":"Nanocarriers; Nanomedicine; Cancer therapy; Medicine; Drug; Combination therapy; Drug delivery; Pharmacology; Cancer treatment; Cancer; Anticancer drug; Nanotechnology; Internal medicine; Materials science","authors":[{"name":"Ruixue Zhang","is_ca":true},{"name":"Ho Lun Wong","is_ca":false},{"name":"Hui Xue","is_ca":false},{"name":"June Young Eoh","is_ca":false},{"name":"Xiao Yu Wu","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02947421398076516,"gpt":0.3227627623326348,"spread":0.2932885483518696,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000809634,0.000865258,0.001303334,0.001440057,0.0002357277,0.001049537,0.0009469723,0.00123246,0.002159828],"category_scores_gemma":[0.0004468769,0.0003502008,0.0005232375,0.001174204,0.000602668,0.001735353,0.0006649253,0.001663502,0.0009787355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004712532,"about_ca_system_score_gemma":0.0006016648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005337203,"about_ca_topic_score_gemma":0.00153645,"domain_scores_codex":[0.9998148,0.00003643132,0.00001945867,0.00003176888,0.00006976756,0.00002792184],"domain_scores_gemma":[0.999781,0.0001037921,0.0000437827,0.000007776472,0.00005000165,0.00001371674],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001450817,0.0002904193,0.0001432747,0.01550631,0.0001146861,0.0004999583,0.000131325,0.001132992,0.02931993,0.01113063,0.01758707,0.9239983],"study_design_scores_gemma":[0.00004708024,0.0004310625,0.0006345416,0.002389468,0.000151521,0.003114961,0.00009116461,0.0008889042,0.009483345,0.003468705,0.9792501,0.0000491309],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003151997,0.9981852,0.0004680959,0.0002085585,0.0001272082,0.000006144319,0.000005982379,0.000006253285,0.0006772819],"genre_scores_gemma":[0.003224095,0.9948217,0.0008436819,0.0001872675,0.0001766779,0.00001299412,0.00001232806,0.000002158939,0.0007191054],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002159828,"threshold_uncertainty_score":0.007225335,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3092740363","doi":"10.1016/j.jconrel.2020.10.020","title":"Challenges in the development and establishment of exosome-based drug delivery systems","year":2020,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":364,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"National Institute for Nanotechnology; University of Waterloo","funders":"Canadian Institutes of Health Research","keywords":"Microvesicles; Exosome; Drug delivery; Drug; Lipid bilayer; Targeted drug delivery; Chemistry; Cell biology; Biology; Pharmacology; Membrane; Biochemistry; microRNA","authors":[{"name":"Jin Wang","is_ca":true},{"name":"Derek Chen","is_ca":true},{"name":"Emmanuel A. Ho","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.034224113478751,"gpt":0.2797032859862144,"spread":0.2454791725074634,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003743535,0.0008698044,0.002171359,0.001233843,0.0004227085,0.00265503,0.001804439,0.002332993,0.001721774],"category_scores_gemma":[0.002065031,0.000672128,0.0006768974,0.001288779,0.001427021,0.004330859,0.001555826,0.003700893,0.001309432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001251731,"about_ca_system_score_gemma":0.001881035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001236203,"about_ca_topic_score_gemma":0.001751237,"domain_scores_codex":[0.9991648,0.0001608674,0.0001025638,0.0001330923,0.0003538055,0.00008495439],"domain_scores_gemma":[0.9987355,0.0006914156,0.0001369681,0.00005179612,0.0003100272,0.00007433559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001375322,0.0001573639,0.0001748827,0.01942682,0.00008627748,0.0003432644,0.0001713349,0.002001013,0.01908757,0.03309638,0.01631799,0.9089997],"study_design_scores_gemma":[0.00004246995,0.0003226708,0.0004455554,0.002828473,0.000108026,0.001026927,0.0001186237,0.0009509815,0.007972075,0.006997044,0.9791271,0.00006007837],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003575981,0.9968758,0.001326053,0.000615144,0.0002012229,0.00001124019,0.00001326547,0.00001114082,0.0005885536],"genre_scores_gemma":[0.002019373,0.9951434,0.001698123,0.0003106421,0.0001960872,0.00002329389,0.00003062076,0.000004811131,0.0005736627],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003743535,"threshold_uncertainty_score":0.01979792,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2407515397","doi":"10.1016/j.jconrel.2016.05.059","title":"Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA","year":2016,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":352,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Acuitas Therapeutics (Canada); University of British Columbia","funders":"Canadian Institutes of Health Research; Alnylam Pharmaceuticals","keywords":"Potency; In vivo; Particle size; Nanoparticle; Chemistry; Pharmacology; Nanotechnology; In vitro; Biophysics; Materials science; Biochemistry; Medicine; Biology; Biotechnology","authors":[{"name":"Sam Chen","is_ca":true},{"name":"Yuen Yi C. Tam","is_ca":true},{"name":"Paulo J.C. Lin","is_ca":true},{"name":"Molly M. H. Sung","is_ca":true},{"name":"Ying K. Tam","is_ca":true},{"name":"Pieter R. Cullis","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.006853339368652107,"gpt":0.2322805146606802,"spread":0.2254271752920281,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004516151,0.0003015872,0.0001928462,0.0001339879,0.0001025576,0.0002714133,0.0001404577,0.0002746065,0.0009022708],"category_scores_gemma":[0.0006777599,0.00019576,0.0001774571,0.00008421644,0.0002432734,0.0003063365,0.0001198937,0.0003653024,0.0002047717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002454532,"about_ca_system_score_gemma":0.0002366899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006126159,"about_ca_topic_score_gemma":0.0007175141,"domain_scores_codex":[0.999823,0.00004796324,0.00001909706,0.00003467049,0.00003761566,0.00003762173],"domain_scores_gemma":[0.9994758,0.0003171789,0.00008431684,0.00002641465,0.00005252365,0.00004374755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006801662,0.00003843278,0.0001065534,0.00002482616,0.000007671843,0.00002076885,0.00002573089,0.0001444812,0.9978589,0.00002809902,0.00002184309,0.001042488],"study_design_scores_gemma":[0.00001386919,0.0005741338,0.0005469086,0.000001505669,0.00001461988,0.00001843117,0.000005504611,0.0004273211,0.9982238,0.000009356633,0.0001613028,0.000003109292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970004,0.000786512,0.001266698,0.0000437158,0.00002992076,0.00001803378,0.0001031804,0.00002029551,0.0007311788],"genre_scores_gemma":[0.9975711,0.0003785292,0.0007474703,0.00003738205,0.00001101527,0.00001905114,0.0001006323,0.00002402569,0.001110671],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009022708,"threshold_uncertainty_score":0.003018379,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2015680138","doi":"10.1016/s0168-3659(99)00200-x","title":"Polycaprolactone–b-poly(ethylene oxide) copolymer micelles as a delivery vehicle for dihydrotestosterone","year":2000,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":350,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Micelle; Copolymer; Critical micelle concentration; Ethylene oxide; Dihydrotestosterone; Biocompatibility; Polycaprolactone; Chemistry; Drug delivery; Caprolactone; HeLa; Polymer chemistry; Materials science; Organic chemistry; In vitro; Polymer; Androgen; Aqueous solution; Biochemistry","authors":[{"name":"Christine Allen","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.009370178976900897,"gpt":0.2593154303751359,"spread":0.249945251398235,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004308685,0.0003022464,0.0002103954,0.000223618,0.0002344421,0.0003401063,0.000234316,0.0004173591,0.0008042043],"category_scores_gemma":[0.0002095296,0.0002333402,0.0001663754,0.0001356099,0.0002000556,0.0006700516,0.0001862556,0.0004990608,0.0004221093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003602899,"about_ca_system_score_gemma":0.0003196997,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005308765,"about_ca_topic_score_gemma":0.0007025894,"domain_scores_codex":[0.9998602,0.00003385327,0.000009718884,0.00003278657,0.00003174706,0.00003163701],"domain_scores_gemma":[0.9998971,0.00003187085,0.00002347643,0.000005874748,0.0000183222,0.00002330618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001407278,0.00003544419,0.00002624045,0.00005375981,0.000004848087,0.0000494519,0.00001336196,0.0001569346,0.9959815,0.0002204968,0.00008158809,0.003235634],"study_design_scores_gemma":[0.00004485549,0.0003868963,0.0002011553,0.000006987677,0.00001810337,0.00009868862,0.000008898695,0.001582616,0.9944009,0.0000358924,0.003208516,0.000006445569],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9520952,0.01167532,0.03074771,0.0005585217,0.0002987277,0.0001506034,0.0001141581,0.0002677331,0.004092101],"genre_scores_gemma":[0.9757342,0.003861416,0.0140774,0.0001367541,0.00008844292,0.00008280709,0.0001099259,0.00006709647,0.005842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008042043,"threshold_uncertainty_score":0.002690375,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2056501647","doi":"10.1016/s0168-3659(03)00327-4","title":"N-acylated chitosan: hydrophobic matrices for controlled drug release","year":2003,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":329,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institut National de la Recherche Scientifique; Université du Québec à Montréal","funders":"","keywords":"Chitosan; Acylation; Chemistry; Swelling; Kinetics; Dissolution; Stereochemistry; Organic chemistry; Materials science; Composite material","authors":[{"name":"Canh Le Tien","is_ca":true},{"name":"Monique Lacroix","is_ca":true},{"name":"Pompilia Ispas‐Szabo","is_ca":true},{"name":"Mircea‐Alexandru Mateescu","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03866949039487608,"gpt":0.3830350198119044,"spread":0.3443655294170282,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002324008,0.0003952661,0.0001111982,0.0002317763,0.0001765764,0.0001962674,0.0001978266,0.0003531796,0.001038189],"category_scores_gemma":[0.0002694804,0.0001779558,0.0001741362,0.0001651127,0.0002377617,0.0003764624,0.0001901631,0.0003147217,0.0003349089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003855246,"about_ca_system_score_gemma":0.0003308071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001820083,"about_ca_topic_score_gemma":0.004055274,"domain_scores_codex":[0.9998759,0.00001893187,0.00001112182,0.00002281052,0.00004783084,0.00002342202],"domain_scores_gemma":[0.9998044,0.00004407476,0.00006655027,0.0000163455,0.00004025453,0.00002836763],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005046742,0.000005906277,0.00001970714,0.00003163518,0.000001692569,0.00003146185,0.000006091258,0.00006572583,0.9980257,0.00006305799,0.00003982042,0.001658809],"study_design_scores_gemma":[0.00000775488,0.00009998624,0.0004079931,0.000002969583,0.000007100327,0.0001094931,0.000004349525,0.0005221831,0.9976719,0.00001751971,0.001143347,0.00000529742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9649994,0.005176199,0.02242549,0.0002845193,0.0001426549,0.0001231386,0.0002173575,0.0002129679,0.006418275],"genre_scores_gemma":[0.9854062,0.001388176,0.008540825,0.00007932122,0.00003032121,0.00003340368,0.00008289787,0.00003468554,0.0044043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001820083,"threshold_uncertainty_score":0.003619015,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2071447376","doi":"10.1016/j.jconrel.2009.04.010","title":"Block copolymer micelles for delivery of cancer therapy: Transport at the whole body, tissue and cellular levels","year":2009,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":328,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance; Natural Sciences and Engineering Research Council of Canada; Breast Cancer Alliance","keywords":"Drug delivery; Cancer therapy; In vivo; Micelle; Cancer; Nanotechnology; Medicine; Chemistry; Materials science; Biology; Internal medicine; Biotechnology","authors":[{"name":"Andrew S. Mikhail","is_ca":true},{"name":"Christine Allen","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02338505234391892,"gpt":0.2957717947256924,"spread":0.2723867423817735,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006215854,0.001047711,0.001171489,0.001082295,0.0002054723,0.0005986685,0.0008899673,0.0009644943,0.00171501],"category_scores_gemma":[0.0002954598,0.0003598167,0.0002737264,0.001019464,0.0003854783,0.001078386,0.000408551,0.001203743,0.002013233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006119005,"about_ca_system_score_gemma":0.0005750043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006836884,"about_ca_topic_score_gemma":0.00129535,"domain_scores_codex":[0.9998406,0.00001698312,0.00001439498,0.00002942664,0.00008033246,0.00001813736],"domain_scores_gemma":[0.99988,0.00004088038,0.00002605923,0.000004902327,0.00003681774,0.0000113622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001352092,0.0001757387,0.00007913189,0.006683016,0.00006621965,0.0003076555,0.00006008818,0.0006643516,0.06505242,0.005417904,0.01677104,0.9045873],"study_design_scores_gemma":[0.00004631258,0.0002572883,0.0004733008,0.0006907662,0.00008433146,0.002355158,0.00002907172,0.0005747293,0.03080635,0.001117759,0.9635275,0.00003744671],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001069401,0.993683,0.002311531,0.0002863337,0.0003917732,0.00002420445,0.00002273533,0.00003040067,0.002180721],"genre_scores_gemma":[0.004679713,0.9865415,0.002866064,0.0002064729,0.000201376,0.00003189486,0.00005162286,0.00000678167,0.005414618],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00171501,"threshold_uncertainty_score":0.005737245,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1996155302","doi":"10.1016/j.jconrel.2006.06.031","title":"Slow release of molecules in self-assembling peptide nanofiber scaffold","year":2006,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Supramolecular Self-Assembly in Materials","field":"Materials Science","cited_by":311,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"National Institute for Nanotechnology; University of Alberta","funders":"","keywords":"Self-healing hydrogels; Chemistry; Bromophenol blue; Nanofiber; Phenol red; Peptide; Sulfonic acid; Pyranine; Polymer chemistry; Biophysics; Chemical engineering; Chromatography; Biochemistry","authors":[{"name":"Yusuke Nagai","is_ca":false},{"name":"Larry D. Unsworth","is_ca":true},{"name":"Sotirios Koutsopoulos","is_ca":false},{"name":"Shuguang Zhang","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.005194907780143662,"gpt":0.2271080907898904,"spread":0.2219131830097467,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001591585,0.0002524177,0.0001778082,0.0001257683,0.0001417218,0.0002044227,0.0001643363,0.0002413243,0.0006893828],"category_scores_gemma":[0.0001770987,0.0001121465,0.0001448056,0.00006648192,0.0001314049,0.0003770181,0.0001443113,0.0002697336,0.0001738509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002008482,"about_ca_system_score_gemma":0.0001343362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002179788,"about_ca_topic_score_gemma":0.0003688107,"domain_scores_codex":[0.999925,0.000007121706,0.000005558595,0.00002234383,0.00001733765,0.00002263468],"domain_scores_gemma":[0.9998667,0.00003192719,0.00004161407,0.00001424248,0.00001576404,0.00002980491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006367779,0.000009821137,0.0000395312,0.00001783535,0.000002322274,0.00003089337,0.00001120251,0.00009773239,0.9989133,0.00006162618,0.00002011396,0.0007319152],"study_design_scores_gemma":[0.00001663787,0.000121868,0.0004325834,0.000001864419,0.000004048165,0.00003560197,0.000004120842,0.001247087,0.9976921,0.00001851904,0.0004223178,0.00000316496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958578,0.0004093434,0.002786087,0.00003264916,0.00001932946,0.00001557026,0.00006133756,0.00005102804,0.0007669064],"genre_scores_gemma":[0.9961547,0.0001746188,0.002192686,0.0000222821,0.00001020957,0.00002008444,0.00005922058,0.00001649815,0.001349745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006893828,"threshold_uncertainty_score":0.002306223,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2017315930","doi":"10.1016/j.jconrel.2009.11.012","title":"Polyester-based micelles and nanoparticles for the parenteral delivery of taxanes","year":2009,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":310,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Université de Montréal","funders":"National Science Council; Canada Research Chairs","keywords":"Paclitaxel; Biocompatibility; Micelle; Polyester; Amphiphile; Nanoparticle; Drug delivery; Chemistry; Drug carrier; Nanotechnology; Copolymer; Materials science; Polymer; Organic chemistry; Aqueous solution; Surgery; Medicine; Chemotherapy","authors":[{"name":"Geneviève Gaucher","is_ca":true},{"name":"R. H. Marchessault","is_ca":true},{"name":"Jean‐Christophe Leroux","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02506714265056624,"gpt":0.2871235429906379,"spread":0.2620564003400716,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005305432,0.000861918,0.00100505,0.001248955,0.0002077161,0.0005581793,0.0008336854,0.0009685881,0.001295032],"category_scores_gemma":[0.0003156258,0.0004560339,0.0003687105,0.0008134716,0.0004282181,0.0009391033,0.0004928621,0.001160196,0.001282949],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006046449,"about_ca_system_score_gemma":0.0005017835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007520621,"about_ca_topic_score_gemma":0.001584303,"domain_scores_codex":[0.9998363,0.00001979714,0.00001871525,0.00003015999,0.00007696549,0.00001792705],"domain_scores_gemma":[0.9999077,0.000030281,0.00002460417,0.000005189225,0.00002342029,0.000008867408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002081874,0.0002509519,0.0000757012,0.008672542,0.000079196,0.0005004525,0.00008550432,0.001235056,0.1175672,0.005588667,0.007084711,0.8586519],"study_design_scores_gemma":[0.0000927816,0.0006207109,0.0007137749,0.001057276,0.0001388092,0.003227683,0.00004915371,0.001202318,0.111944,0.001266571,0.8796241,0.0000628501],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002318552,0.9927731,0.002513248,0.0001570524,0.0002640264,0.00002761904,0.00001720725,0.00002934021,0.001899909],"genre_scores_gemma":[0.009873297,0.97978,0.003311189,0.0001759679,0.0001693429,0.00004033317,0.00005189754,0.000009318978,0.006588739],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001295032,"threshold_uncertainty_score":0.004387021,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2136226057","doi":"10.1016/j.jconrel.2014.04.017","title":"Assessment of PEG on polymeric particles surface, a key step in drug carrier translation","year":2014,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":310,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"","keywords":"Nanocarriers; PEG ratio; Ethylene glycol; Nanotechnology; Polymer; Drug delivery; Materials science; Drug; Protein adsorption; Chemistry; Nanoparticle; Chemical engineering; Organic chemistry; Pharmacology; Medicine","authors":[{"name":"Jean‐Michel Rabanel","is_ca":true},{"name":"Patrice Hildgen","is_ca":true},{"name":"Xavier Banquy","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01979722632375995,"gpt":0.3076613256877593,"spread":0.2878640993639994,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005224439,0.000761685,0.0005964934,0.0006651443,0.0001417329,0.0004080544,0.000421372,0.0007932822,0.0005817018],"category_scores_gemma":[0.0004050429,0.0002711544,0.0003105667,0.000370471,0.0004290571,0.0007992488,0.000359212,0.000857575,0.0004232224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004281178,"about_ca_system_score_gemma":0.0003182737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004443191,"about_ca_topic_score_gemma":0.0008224639,"domain_scores_codex":[0.999714,0.00003652283,0.00001886251,0.00005349832,0.000148592,0.00002858252],"domain_scores_gemma":[0.999866,0.00004955429,0.0000372325,0.000006956394,0.00003433576,0.000005960103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008257888,0.00006487071,0.0001823696,0.004318736,0.00003704836,0.0002986614,0.00009055783,0.000581086,0.7305383,0.002747882,0.001306505,0.2597515],"study_design_scores_gemma":[0.00001477328,0.0004207058,0.001367462,0.0003349903,0.00008444253,0.001129237,0.00005378834,0.001139068,0.8812237,0.0007485005,0.1134521,0.00003114494],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05127024,0.892341,0.04239658,0.0007613356,0.0006029608,0.0002381898,0.0001083351,0.0001458983,0.01213552],"genre_scores_gemma":[0.223073,0.7393439,0.02374755,0.0005569824,0.0002511817,0.0002087065,0.00017534,0.00003967323,0.01260362],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0007932822,"threshold_uncertainty_score":0.003106296,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1994467229","doi":"10.1016/s0168-3659(02)00146-3","title":"Thermosensitive chitosan-based hydrogel containing liposomes for the delivery of hydrophilic molecules","year":2002,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Hydrogels: synthesis, properties, applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":305,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"","keywords":"Liposome; Kinetics; Chitosan; Chemistry; Drug delivery; Controlled release; Chromatography; Delivery system; Biophysics; Biochemistry; Organic chemistry; Materials science; Nanotechnology; Biomedical engineering","authors":[{"name":"Ève Ruel-Gariépy","is_ca":true},{"name":"Grégoire Leclair","is_ca":true},{"name":"Patrice Hildgen","is_ca":true},{"name":"Anand Gupta","is_ca":false},{"name":"Jean‐Christophe Leroux","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01360818112735547,"gpt":0.2256893642178409,"spread":0.2120811830904854,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020467,0.0002679839,0.0001325984,0.0002022698,0.0001246535,0.0002166609,0.0002492073,0.0003104761,0.0008504595],"category_scores_gemma":[0.0001737246,0.0001733358,0.0001966908,0.000115475,0.0001962676,0.0003857948,0.0002164128,0.0004083554,0.0002334297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004617042,"about_ca_system_score_gemma":0.000238897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005838026,"about_ca_topic_score_gemma":0.001002564,"domain_scores_codex":[0.9999288,0.000009298053,0.000007102815,0.00001438683,0.00001892091,0.00002135075],"domain_scores_gemma":[0.9998745,0.0000306442,0.00003618933,0.00001110367,0.00001979614,0.00002771339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005167037,0.000008124329,0.00002052555,0.00003060025,0.000002000722,0.00001817381,0.000007866841,0.0000672704,0.9987043,0.0001177091,0.0000344235,0.0009372241],"study_design_scores_gemma":[0.00001363986,0.00006053122,0.0002065225,0.000003123265,0.000008175393,0.00005164992,0.000003659565,0.0005510881,0.9982187,0.00002023263,0.0008572533,0.000005326688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9741935,0.004056842,0.0185515,0.0002424422,0.00008395781,0.00009311966,0.0002947532,0.0002214214,0.002262443],"genre_scores_gemma":[0.9879995,0.001177105,0.007542861,0.00007305065,0.00001616378,0.00004144813,0.0001470212,0.00004203721,0.002960832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008504595,"threshold_uncertainty_score":0.003349841,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1978128526","doi":"10.1016/s0168-3659(99)00285-0","title":"Preparation and evaluation of the in vitro drug release properties and mucoadhesion of novel microspheres of hyaluronic acid and chitosan","year":2000,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":293,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"St. Thomas Hospital","funders":"","keywords":"Mucoadhesion; Chemistry; Chitosan; Bioavailability; Gelatin; Excipient; Dosage form; Hyaluronic acid; Nasal administration; Chromatography; Controlled release; Drug delivery; Drug carrier; Pharmacology; Nuclear chemistry; Biochemistry; Organic chemistry; Medicine","authors":[{"name":"Sian Lim","is_ca":false},{"name":"Gary P. Martin","is_ca":false},{"name":"David J. Berry","is_ca":true},{"name":"Marc B. Brown","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05826768971070611,"gpt":0.373531267738365,"spread":0.3152635780276589,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004609428,0.0003698591,0.000301513,0.0002319691,0.0001956542,0.0002385867,0.0002214945,0.0004556302,0.0004484896],"category_scores_gemma":[0.0004041908,0.0002442212,0.0004636172,0.0001968696,0.0003152424,0.0003928384,0.0001583954,0.0003866264,0.0001150232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003668645,"about_ca_system_score_gemma":0.0003576417,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001432854,"about_ca_topic_score_gemma":0.001680064,"domain_scores_codex":[0.9997944,0.00002442386,0.0000271322,0.00004009788,0.00007254253,0.00004130496],"domain_scores_gemma":[0.9996617,0.0000740186,0.0001255205,0.00002978241,0.0000631807,0.0000458732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000764898,0.00002341714,0.00007183517,0.00003068719,0.000005322047,0.00002593119,0.00001082092,0.00006613513,0.9989719,0.000023571,0.000004078703,0.0006898153],"study_design_scores_gemma":[0.00001411014,0.0004881228,0.001462424,0.00000184872,0.00002037837,0.00008061076,0.000006095986,0.0004047108,0.9972098,0.000007460237,0.0002987197,0.000005696837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928778,0.001682934,0.004768568,0.00003570016,0.00002576787,0.00006596478,0.0001130248,0.00002645201,0.0004037701],"genre_scores_gemma":[0.9923691,0.0009326938,0.0052046,0.00002106604,0.00001626577,0.00004179493,0.0001659186,0.00001748747,0.001231161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001432854,"threshold_uncertainty_score":0.002848983,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1987846184","doi":"10.1016/j.jconrel.2011.09.093","title":"Uptake mechanisms of non-viral gene delivery","year":2011,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":285,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Hôpital du Sacré-Cœur de Montréal; Université de Montréal","funders":"National Natural Science Foundation of China","keywords":"Endocytic cycle; Gene delivery; Gene; Cell biology; Biology; Computational biology; Intracellular; Mechanism (biology); Endocytosis; Cell; Transfection; Genetics","authors":[{"name":"Shengnan Xiang","is_ca":false},{"name":"Haijun Tong","is_ca":true},{"name":"Qin Shi","is_ca":true},{"name":"Julio Fernandes","is_ca":true},{"name":"Tuo Jin","is_ca":false},{"name":"Kerong Dai","is_ca":false},{"name":"Xiaoling Zhang","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01438185446505861,"gpt":0.247810336494285,"spread":0.2334284820292264,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009736269,0.001540596,0.002584807,0.001857115,0.0003961342,0.002184594,0.002043125,0.002130056,0.001403373],"category_scores_gemma":[0.0006779698,0.0006199633,0.0006740094,0.002191883,0.001727726,0.002672953,0.001239931,0.002012198,0.001941136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001440493,"about_ca_system_score_gemma":0.0008196653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005998476,"about_ca_topic_score_gemma":0.0005799436,"domain_scores_codex":[0.9995701,0.00005915375,0.00005334619,0.00008312751,0.0001831819,0.00005105917],"domain_scores_gemma":[0.9996191,0.0001808944,0.00005774166,0.00002305559,0.00009753366,0.00002168646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001790651,0.0001347423,0.0001646169,0.01737769,0.00006735003,0.0006732603,0.0001532861,0.001475512,0.04577729,0.02317085,0.01388077,0.8969455],"study_design_scores_gemma":[0.00003078437,0.0002225584,0.0006155723,0.002157835,0.0001164147,0.003221374,0.0001081234,0.001159876,0.02717558,0.0101416,0.9549728,0.00007754208],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004802867,0.9953842,0.002307819,0.0001911891,0.0002879877,0.00000914721,0.00001659404,0.00002124909,0.001301636],"genre_scores_gemma":[0.003276113,0.9928255,0.001544382,0.0001585547,0.0002469181,0.00002126476,0.00004658203,0.000007605851,0.001872995],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002584807,"threshold_uncertainty_score":0.01045156,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2094100731","doi":"10.1016/j.jconrel.2011.04.028","title":"Engineering of amphiphilic block copolymers for polymeric micellar drug and gene delivery","year":2011,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":265,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Tata Trusts; Alberta Cancer Foundation","keywords":"Drug delivery; Amphiphile; Micelle; Nanotechnology; Gene delivery; Rational design; Copolymer; Drug carrier; Drug; Flexibility (engineering); Polymer; Materials science; Chemistry; Computer science; Organic chemistry; Pharmacology; Genetic enhancement; Medicine; Mathematics","authors":[{"name":"Xiao-Bing Xiong","is_ca":true},{"name":"Arash Falamarzian","is_ca":true},{"name":"Shyam M. Garg","is_ca":true},{"name":"Afsaneh Lavasanifar","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0142912169066224,"gpt":0.2389122569692512,"spread":0.2246210400626288,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003721135,0.0007936028,0.0005336562,0.0006930098,0.0001627639,0.0004650113,0.0004959915,0.0006341959,0.0007572027],"category_scores_gemma":[0.0001987511,0.0003691273,0.0002868814,0.0005865297,0.0003231727,0.0008551311,0.0003847483,0.0008746827,0.0007897508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005952567,"about_ca_system_score_gemma":0.0003743303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005348152,"about_ca_topic_score_gemma":0.0009782591,"domain_scores_codex":[0.9998591,0.00001572854,0.00001362223,0.000025326,0.00005937032,0.00002689418],"domain_scores_gemma":[0.9999284,0.00001703285,0.00002662042,0.000004490946,0.00001633409,0.000007145956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000837414,0.0001677895,0.000110756,0.003222591,0.00003534746,0.0003535062,0.0000721549,0.001203084,0.7042312,0.005373913,0.001731242,0.2834147],"study_design_scores_gemma":[0.00004982467,0.0004308458,0.0009298045,0.0003568922,0.00008968048,0.001724832,0.0000365399,0.002414192,0.6818623,0.001044487,0.3110082,0.00005244888],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04284077,0.9218753,0.02578685,0.0004981486,0.0004791159,0.0001394157,0.00009242484,0.0001749592,0.008112951],"genre_scores_gemma":[0.1420772,0.8144537,0.02692313,0.0003297161,0.0002056773,0.00015649,0.0002129417,0.00005341219,0.01558777],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0007936028,"threshold_uncertainty_score":0.004318893,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2123255383","doi":"10.1016/j.jconrel.2004.06.018","title":"Poly(N-vinylpyrrolidone)-block-poly(d,l-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation","year":2004,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":252,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Micropharma (Canada); Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"In vivo; Pharmacology; Pharmacokinetics; Chemistry; Paclitaxel; Bioavailability; Biodistribution; Solubility; Etoposide; Amphiphile; Drug; In vitro; Cancer; Medicine; Biochemistry; Chemotherapy; Copolymer; Organic chemistry","authors":[{"name":"Dorothée Le Garrec","is_ca":true},{"name":"Sandra Gori","is_ca":true},{"name":"Lan Luo","is_ca":true},{"name":"D. Lessard","is_ca":true},{"name":"D.C. Smith","is_ca":true},{"name":"M.-A. Yessine","is_ca":true},{"name":"M. Ranger","is_ca":true},{"name":"Jean‐Christophe Leroux","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.009719324383742406,"gpt":0.2675669498889162,"spread":0.2578476255051738,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003273062,0.0004134576,0.0002870092,0.000300527,0.0001581197,0.0002228611,0.0002016982,0.0002788638,0.0003865825],"category_scores_gemma":[0.0001703912,0.000235217,0.0002000535,0.0001514219,0.0002309423,0.0003421584,0.0001291524,0.0003597956,0.0002296067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002584432,"about_ca_system_score_gemma":0.0002644163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000690972,"about_ca_topic_score_gemma":0.001312801,"domain_scores_codex":[0.9998945,0.00002822899,0.000005420879,0.00002293709,0.00002694893,0.00002196832],"domain_scores_gemma":[0.999887,0.00003396257,0.00003189454,0.00000840939,0.00001469911,0.00002405642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001966633,0.00006560388,0.00004581461,0.00004131406,0.000005527907,0.00003898428,0.00001056503,0.0001764321,0.9955556,0.00005368007,0.00003408311,0.003775792],"study_design_scores_gemma":[0.00002519326,0.0008964841,0.0005298088,0.000002791078,0.00001771293,0.0001218798,0.000003628038,0.001155316,0.9962846,0.00001019043,0.0009484697,0.000004035279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9746463,0.009136728,0.01387281,0.0001197373,0.00005909441,0.00009088635,0.0001102594,0.0002193964,0.00174477],"genre_scores_gemma":[0.9835992,0.004120419,0.008721354,0.0000410681,0.00003200296,0.000047851,0.0001463064,0.00005368522,0.003238117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000690972,"threshold_uncertainty_score":0.001875162,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2779315772","doi":"10.1016/j.jconrel.2017.12.019","title":"Organogels, promising drug delivery systems: an update of state-of-the-art and recent applications","year":2017,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Supramolecular Self-Assembly in Materials","field":"Materials Science","cited_by":248,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"","keywords":"Transdermal; Cosmetics; Drug delivery; Biocompatible material; Nanotechnology; Active ingredient; Delivery system; Chemistry; Materials science; Biochemical engineering; Organic chemistry; Pharmacology; Biomedical engineering; Medicine; Engineering","authors":[{"name":"Cloé L. Esposito","is_ca":true},{"name":"Plamen Kirilov","is_ca":false},{"name":"Gaëlle Roullin","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0289461181536136,"gpt":0.3145960283990386,"spread":0.285649910245425,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007909996,0.0008670052,0.001188064,0.001947918,0.0002373163,0.001188766,0.0008087206,0.001009033,0.00228107],"category_scores_gemma":[0.0006974373,0.0003060726,0.0003795676,0.002020336,0.0004727744,0.001820848,0.0006497555,0.001522688,0.0009633046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004366284,"about_ca_system_score_gemma":0.0008714786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004789321,"about_ca_topic_score_gemma":0.00146277,"domain_scores_codex":[0.9997929,0.00002268469,0.00002743505,0.00003882531,0.00009082404,0.00002744502],"domain_scores_gemma":[0.9995517,0.000230767,0.00006973191,0.00001002499,0.00009746971,0.00004027415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008659242,0.00008957757,0.0002376484,0.02150982,0.00007352047,0.0001866877,0.00006519991,0.0003332736,0.01119882,0.004684267,0.02078966,0.9407449],"study_design_scores_gemma":[0.00001777741,0.0001365022,0.0006606044,0.002000999,0.0001207483,0.001242896,0.00006819563,0.000249848,0.003955076,0.001588793,0.9899269,0.0000315887],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001860171,0.9990478,0.000148646,0.0001105143,0.0001154209,0.000002952549,0.00001558673,0.000006056552,0.0003668692],"genre_scores_gemma":[0.001196425,0.9977181,0.0003972991,0.0001226827,0.000140248,0.000004638693,0.00002971728,0.000001734165,0.0003892416],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00228107,"threshold_uncertainty_score":0.007630944,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2022295294","doi":"10.1016/j.jconrel.2004.02.021","title":"Sustained delivery of vascular endothelial growth factor with alginate beads","year":2004,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Electrospun Nanofibers in Biomedical Applications","field":"Materials Science","cited_by":246,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Queen's University","funders":"","keywords":"Vascular endothelial growth factor; Angiogenesis; Chemistry; In vitro; Therapeutic angiogenesis; Calcium alginate; Blood vessel; Calcium; Biophysics; VEGF receptors; Biomedical engineering; Biochemistry; Cancer research; Biology; Medicine; Internal medicine","authors":[{"name":"Frank Gu","is_ca":true},{"name":"Brian G. Amsden","is_ca":true},{"name":"Ronald J. Neufeld","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.003757563056651071,"gpt":0.2127087682364757,"spread":0.2089512051798247,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002599008,0.000347777,0.0002867999,0.0002382498,0.000192685,0.000618493,0.0002751896,0.0004796935,0.0004788912],"category_scores_gemma":[0.0002227064,0.0002173218,0.0003721773,0.0001552393,0.0001944796,0.0005029078,0.0002970344,0.000494512,0.0002203898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007035687,"about_ca_system_score_gemma":0.0004011727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00163558,"about_ca_topic_score_gemma":0.002315632,"domain_scores_codex":[0.9998011,0.00001527791,0.00001989167,0.00004384333,0.00004339826,0.00007655782],"domain_scores_gemma":[0.9998589,0.00002967869,0.00004512203,0.0000142846,0.00001943178,0.0000325302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001581203,0.00003516707,0.00006012806,0.00003366519,0.000008299789,0.00004601319,0.00001920857,0.0002160715,0.996439,0.0001341512,0.00005010858,0.002800044],"study_design_scores_gemma":[0.00002261059,0.0001853731,0.0003521742,0.000003518204,0.00001473504,0.00003696074,0.000007044588,0.001062763,0.9975387,0.00002296065,0.0007457223,0.000007485328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894265,0.002337383,0.006545509,0.0001130327,0.00009666741,0.00003103194,0.0001135788,0.0001276895,0.001208637],"genre_scores_gemma":[0.9930689,0.0005662702,0.003538192,0.0000457123,0.00002613329,0.00002256834,0.00006153873,0.00002444932,0.002646227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00163558,"threshold_uncertainty_score":0.00510478,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2219182836","doi":"10.1016/j.jconrel.2015.12.012","title":"Non-viral gene therapy: Gains and challenges of non-invasive administration methods","year":2015,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":236,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canada Foundation for Innovation","keywords":"Genetic enhancement; Medicine; Transdermal; Gene delivery; Viral vector; Intensive care medicine; Pharmacology; Bioinformatics; Gene; Biology","authors":[{"name":"Marianna Földvári","is_ca":true},{"name":"Ding-Wen Chen","is_ca":true},{"name":"Nafiseh Nafissi","is_ca":true},{"name":"Daniella Calderon","is_ca":true},{"name":"Lokesh Narsineni","is_ca":true},{"name":"Amirreza Rafiee","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07222471079563451,"gpt":0.3890484520857828,"spread":0.3168237412901483,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001332054,0.000777152,0.001467848,0.00157725,0.0003399035,0.001363008,0.001361183,0.001351012,0.002255478],"category_scores_gemma":[0.0009182916,0.0003494033,0.0005305785,0.001358637,0.001359612,0.001943237,0.000831039,0.002507835,0.001313278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007631959,"about_ca_system_score_gemma":0.0009668938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006610294,"about_ca_topic_score_gemma":0.001204862,"domain_scores_codex":[0.999588,0.00006613843,0.00003618924,0.00006435736,0.0002045499,0.00004069304],"domain_scores_gemma":[0.9993298,0.0004195121,0.00007294105,0.0000264742,0.0001147237,0.00003655258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001235625,0.0001439473,0.0001982661,0.01212932,0.00006394641,0.0002311542,0.0001430032,0.0005941269,0.01668719,0.02090059,0.01880919,0.9299757],"study_design_scores_gemma":[0.00001751634,0.0001972679,0.0005477687,0.001567669,0.00007298024,0.001253748,0.00009523656,0.0004199174,0.007130067,0.005699959,0.9829533,0.00004449418],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000296258,0.9961423,0.001598472,0.0003570818,0.0002598822,0.000007241585,0.00001478223,0.00001623071,0.001307698],"genre_scores_gemma":[0.002757547,0.9939407,0.001529806,0.0002793187,0.0002378092,0.00001615789,0.00002763555,0.000006055991,0.001205129],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002255478,"threshold_uncertainty_score":0.007545292,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2897789147","doi":"10.1016/j.jconrel.2018.10.015","title":"PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake","year":2018,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":230,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Acuitas Therapeutics (Canada)","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health; amfAR, The Foundation for AIDS Research","keywords":"Messenger RNA; Systemic administration; Apolipoprotein B; RNA; Chemistry; Molecular biology; Biology; In vivo; Biochemistry; Gene; Cholesterol","authors":[{"name":"Hamideh Parhiz","is_ca":false},{"name":"Vladimir V. Shuvaev","is_ca":false},{"name":"Norbert Pardi","is_ca":false},{"name":"Makan Khoshnejad","is_ca":false},{"name":"Raisa Y. Kiseleva","is_ca":false},{"name":"Thomas Uhler","is_ca":false},{"name":"Steven Tuyishime","is_ca":false},{"name":"Barbara L. Mui","is_ca":true},{"name":"Ying K. Tam","is_ca":true},{"name":"Thomas D. Madden","is_ca":true},{"name":"Michael J. Hope","is_ca":true},{"name":"Drew Weissman","is_ca":false},{"name":"Vladimir R. Muzykantov","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.006494933034548196,"gpt":0.2366028441511072,"spread":0.230107911116559,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005041617,0.000462223,0.0003448231,0.0002430008,0.0001528572,0.000493934,0.0002914895,0.000649359,0.001506908],"category_scores_gemma":[0.0002500792,0.0002576527,0.0003387195,0.0001297864,0.0003737267,0.0003497237,0.0003131948,0.001292887,0.0005807077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004143214,"about_ca_system_score_gemma":0.0003006889,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005840298,"about_ca_topic_score_gemma":0.0008858104,"domain_scores_codex":[0.9995803,0.00004955496,0.00003668965,0.00009252825,0.0001080404,0.0001327892],"domain_scores_gemma":[0.9997424,0.00009268228,0.00004308072,0.00003893355,0.00003211511,0.00005085326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003061364,0.00001598967,0.00001527282,0.0000130378,0.000001188919,0.00001864293,0.000005255077,0.0000254041,0.9994355,0.00004845312,0.00002231722,0.0003682107],"study_design_scores_gemma":[0.000005309381,0.00006402416,0.0002894429,0.00000130491,0.000003572772,0.00004241298,0.000004726605,0.0002691151,0.9989086,0.00001033682,0.0003996891,0.000001356296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9700882,0.002370638,0.02064106,0.000376475,0.0002011456,0.00013593,0.0006049754,0.0007606923,0.004820941],"genre_scores_gemma":[0.9802884,0.000695256,0.008784277,0.0001511021,0.00002387796,0.00009318538,0.0005463605,0.00008052672,0.009337083],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001506908,"threshold_uncertainty_score":0.005041063,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2980442678","doi":"10.1016/j.jconrel.2019.10.022","title":"Polymeric microneedles for controlled transdermal drug delivery","year":2019,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":224,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Cape Breton University","funders":"Canada Research Chairs; China Postdoctoral Science Foundation; Cape Breton University","keywords":"Transdermal; Drug delivery; Stratum corneum; Drug; Controlled release; Biocompatible material; Systemic circulation; Pharmacology; Nanotechnology; Biomedical engineering; Chemistry; Materials science; Medicine","authors":[{"name":"Parbeen Singh","is_ca":false},{"name":"Andrew Carrier","is_ca":true},{"name":"Yongli Chen","is_ca":false},{"name":"Sujing Lin","is_ca":false},{"name":"Jinlin Wang","is_ca":false},{"name":"Shufen Cui","is_ca":false},{"name":"Xu Zhang","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1203973175907222,"gpt":0.453359457677718,"spread":0.3329621400869958,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003659685,0.000729234,0.0008710623,0.001659208,0.0001452882,0.0005721519,0.0005503078,0.0006480063,0.00265172],"category_scores_gemma":[0.000309318,0.0002803387,0.0003441016,0.001643577,0.0002970723,0.000825296,0.0004908703,0.001245934,0.001252805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003628695,"about_ca_system_score_gemma":0.0004776253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006446789,"about_ca_topic_score_gemma":0.001243765,"domain_scores_codex":[0.9998583,0.00001219047,0.00001374536,0.00002590123,0.00007229453,0.00001752453],"domain_scores_gemma":[0.9998717,0.00005251881,0.00003479222,0.000005016053,0.00002674237,0.000009240454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006631066,0.0001303308,0.00008095988,0.01127806,0.00006613043,0.0001251808,0.00003783741,0.0005717195,0.03302634,0.003277342,0.008292459,0.9430473],"study_design_scores_gemma":[0.00004093514,0.000352342,0.001170076,0.001887902,0.0001689806,0.00099379,0.00004302343,0.0006661264,0.02233712,0.001371492,0.9709203,0.00004784908],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001137025,0.9951338,0.001422117,0.0001534094,0.0002406308,0.00001578316,0.00004197866,0.00002897639,0.001826355],"genre_scores_gemma":[0.005076934,0.9899396,0.001569238,0.0001542636,0.0001553988,0.00001763552,0.00006327062,0.000005029149,0.003018624],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00265172,"threshold_uncertainty_score":0.0088709,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2092723839","doi":"10.1016/s0168-3659(01)00517-x","title":"Factors affecting protein release from alginate–chitosan coacervate microcapsules during production and gastric/intestinal simulation","year":2001,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Microencapsulation and Drying Processes","field":"Agricultural and Biological Sciences","cited_by":222,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval","funders":"","keywords":"Chemistry; Coacervate; Chitosan; Calcium alginate; Chromatography; Bovine serum albumin; Incubation; Acetone; Calcium; Albumin; Biochemistry; Organic chemistry","authors":[{"name":"Grant W. Vandenberg","is_ca":false},{"name":"Cédric Drolet","is_ca":true},{"name":"Susan Scott","is_ca":true},{"name":"J. de la Noüe","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01934065643833735,"gpt":0.2302507683605875,"spread":0.2109101119222502,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006934019,0.0003920887,0.0003070871,0.0001923577,0.0002010661,0.0006461759,0.0001916548,0.0003053853,0.0006604925],"category_scores_gemma":[0.001253437,0.0002636661,0.0002645406,0.0002650268,0.0004129987,0.0005125429,0.0002079757,0.0003583932,0.0001981989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004922875,"about_ca_system_score_gemma":0.000347951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001475809,"about_ca_topic_score_gemma":0.001484577,"domain_scores_codex":[0.999571,0.00009045272,0.00005416008,0.00007729109,0.00007989766,0.000127006],"domain_scores_gemma":[0.9990958,0.0004664329,0.0001809846,0.00004554831,0.0001260255,0.00008518151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007189883,0.00003096135,0.0003185071,0.00004129506,0.000007280979,0.00004636278,0.00004709028,0.0002583581,0.9976718,0.00002589865,0.00001955891,0.0008140926],"study_design_scores_gemma":[0.000009478848,0.0001593525,0.001135113,0.000001795858,0.00001165468,0.00001667634,0.00001909173,0.0004998822,0.9980018,0.00000706938,0.0001335443,0.000004492675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980654,0.0003196386,0.001077701,0.00002600447,0.00001216647,0.00002000103,0.0001122053,0.00002250452,0.0003444594],"genre_scores_gemma":[0.9983925,0.0001481501,0.0008054562,0.00001803447,0.000004402245,0.0000174888,0.0001168056,0.00002176944,0.0004752981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001475809,"threshold_uncertainty_score":0.003667057,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2109082151","doi":"10.1016/j.jconrel.2010.04.026","title":"Slow and sustained release of active cytokines from self-assembling peptide scaffolds","year":2010,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Supramolecular Self-Assembly in Materials","field":"Materials Science","cited_by":217,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta; National Institute for Nanotechnology","funders":"National Institute of Biomedical Imaging and Bioengineering; Regione Lombardia; Fondazione Cariplo","keywords":"Self-assembling peptide; Regenerative medicine; Nanofiber; Peptide; Chemistry; Scaffold; Biophysics; Nanotechnology; Cell biology; Cell; Materials science; Biochemistry; Biology; Medicine; Biomedical engineering","authors":[{"name":"Fabrizio Gelain","is_ca":false},{"name":"Larry D. Unsworth","is_ca":true},{"name":"Shuguang Zhang","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.004658738140706471,"gpt":0.234422141424824,"spread":0.2297634032841175,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001983973,0.000258285,0.0001888074,0.00009635181,0.0001006091,0.0002988147,0.0001474453,0.0002293588,0.0005390574],"category_scores_gemma":[0.0002204697,0.0001304434,0.0001341243,0.00008045573,0.0001674233,0.0003423213,0.0001895681,0.0003875681,0.0002314811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001711929,"about_ca_system_score_gemma":0.0001262954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001328587,"about_ca_topic_score_gemma":0.0002531433,"domain_scores_codex":[0.9999024,0.00001066266,0.000007610907,0.00002274497,0.0000229819,0.00003360547],"domain_scores_gemma":[0.9998578,0.00004213837,0.00003824902,0.00001735864,0.00001639427,0.00002796912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001002964,0.000013535,0.00004806994,0.00001704357,0.000002239338,0.00002661625,0.00001813105,0.0001189929,0.9981217,0.00006149816,0.0000280611,0.001443833],"study_design_scores_gemma":[0.00002754261,0.0001178159,0.0003264899,0.000001598697,0.000003631232,0.00003111449,0.000004962189,0.0008962428,0.998075,0.00001872175,0.0004939479,0.000002949697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935915,0.0007774864,0.00464591,0.0000440869,0.00002173926,0.00002359383,0.0000926037,0.00005306365,0.000749839],"genre_scores_gemma":[0.9960905,0.0002257074,0.002444358,0.0000238126,0.000008620965,0.00002308881,0.00006532781,0.00001879378,0.001099822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005390574,"threshold_uncertainty_score":0.001803339,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2987798976","doi":"10.1016/j.jconrel.2019.10.028","title":"Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening","year":2019,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":215,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Harvard School of Engineering and Applied Sciences; National Cancer Institute; National Institutes of Health; Interface; Canadian Aeronautics and Space Institute; Burroughs Wellcome Fund; American Cancer Society; American Association for Cancer Research; National Center for Advancing Translational Sciences; Foundation for the National Institutes of Health","keywords":"In vivo; Messenger RNA; Nucleic acid; Context (archaeology); RNA; Biology; Chemistry; Cell biology; Molecular biology; Biochemistry; Genetics; Gene","authors":[{"name":"Pedro Pires Goulart Guimarães","is_ca":false},{"name":"Rui Zhang","is_ca":false},{"name":"Roman Spektor","is_ca":false},{"name":"Amanda Chung","is_ca":false},{"name":"Margaret M. Billingsley","is_ca":false},{"name":"Rakan El‐Mayta","is_ca":false},{"name":"Rachel Riley","is_ca":false},{"name":"Lili Wang","is_ca":false},{"name":"James M. Wilson","is_ca":false},{"name":"Michael J. Mitchell","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01401399459647351,"gpt":0.2515796410825852,"spread":0.2375656464861117,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003565016,0.0003929482,0.0002234411,0.0001868812,0.0001562388,0.0003150098,0.0002645908,0.0004225111,0.0006807259],"category_scores_gemma":[0.0002203789,0.0002151157,0.0001758576,0.0001147927,0.0002174839,0.0002305357,0.000234933,0.0004445646,0.0003531685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003919473,"about_ca_system_score_gemma":0.0001960916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000415531,"about_ca_topic_score_gemma":0.0006993058,"domain_scores_codex":[0.9997403,0.00005154001,0.00001239615,0.00006232643,0.00008733929,0.00004605816],"domain_scores_gemma":[0.9998511,0.00004085823,0.00004711701,0.00001473339,0.00002959725,0.0000166523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002196618,0.000005797339,0.00001784727,0.000009585034,9.579254e-7,0.00001391993,0.000005423731,0.00003867199,0.9992686,0.00006437853,0.00001595532,0.0005369766],"study_design_scores_gemma":[0.000002587755,0.00003490219,0.00007556847,6.081248e-7,0.000002785729,0.00002222799,0.000002437387,0.000406967,0.9991379,0.000008293517,0.000304172,0.000001533688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9294409,0.0008219359,0.06515595,0.0001944465,0.00006048044,0.0001844888,0.0003439472,0.0005056663,0.003292239],"genre_scores_gemma":[0.9587449,0.0006450599,0.03272841,0.00008044096,0.00001144181,0.00009948055,0.0003171439,0.0001043391,0.007268845],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006807259,"threshold_uncertainty_score":0.002843797,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2040364087","doi":"10.1016/j.jconrel.2010.11.033","title":"Neurotherapeutic applications of nanoparticles in Alzheimer's disease","year":2010,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":212,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval; Institut National de la Recherche Scientifique","funders":"","keywords":"Nanocarriers; Medicine; Disease; Drug; Drug delivery; Population; Blood–brain barrier; Pharmacology; Neuroscience; Central nervous system; Internal medicine; Psychology; Chemistry","authors":[{"name":"Jasjeet Kaur Sahni","is_ca":true},{"name":"Sihem Doggui","is_ca":true},{"name":"Javed Ali","is_ca":false},{"name":"Sanjula Baboota","is_ca":false},{"name":"Lê H. Dao","is_ca":true},{"name":"Charles Ramassamy","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04238325654730239,"gpt":0.3714790338006795,"spread":0.3290957772533771,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003976183,0.0009796899,0.001487055,0.001404215,0.0001952645,0.0005501576,0.0006118229,0.0008720019,0.001529606],"category_scores_gemma":[0.0002775529,0.000293024,0.0004575012,0.001086341,0.0003297061,0.0007185822,0.0004495112,0.0009725008,0.0009604151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000355521,"about_ca_system_score_gemma":0.0004136497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009614877,"about_ca_topic_score_gemma":0.001550185,"domain_scores_codex":[0.9998808,0.00001560456,0.0000151271,0.00002061238,0.00005274777,0.00001503852],"domain_scores_gemma":[0.9998822,0.00004970684,0.00002653252,0.000004589743,0.00002798111,0.00000888157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001547604,0.0001834497,0.00009727896,0.01272099,0.00008767644,0.0003133574,0.00005418543,0.0005628775,0.02614635,0.00192721,0.00899436,0.9487575],"study_design_scores_gemma":[0.0000911611,0.0004846461,0.001361282,0.002747567,0.0002783449,0.003497366,0.00007626411,0.0004645748,0.0181401,0.001529376,0.9712819,0.00004736539],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008751703,0.9973194,0.0004319955,0.0001018938,0.0001511611,0.00001281864,0.00001637877,0.00001213066,0.001079097],"genre_scores_gemma":[0.004087457,0.9932716,0.0006989,0.0001229424,0.0001151414,0.00001553541,0.00003344029,0.000002925929,0.001652003],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001529606,"threshold_uncertainty_score":0.005117059,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1992349487","doi":"10.1016/j.jconrel.2007.06.022","title":"Low temperature direct 3D printed bioceramics and biocomposites as drug release matrices","year":2007,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Bone Tissue Engineering Materials","field":"Engineering","cited_by":211,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"Canada Research Chairs","keywords":"Ofloxacin; Adsorption; Tetracycline; Microporous material; Desorption; Chemistry; Polymer; Brushite; Kinetics; Nuclear chemistry; Ceramic; Chemical engineering; Materials science; Organic chemistry; Antibiotics; Phosphate; Ciprofloxacin; Biochemistry","authors":[{"name":"Uwe Gbureck","is_ca":false},{"name":"Elke Vorndran","is_ca":false},{"name":"Frank A. Müller","is_ca":false},{"name":"Jake E. Barralet","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.002110317888460815,"gpt":0.1964890205581816,"spread":0.1943787026697208,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002351755,0.000294443,0.0002604572,0.0002446141,0.0001103539,0.00051322,0.0002436794,0.0004727301,0.0008761357],"category_scores_gemma":[0.0002732291,0.0003658221,0.0002639843,0.000157028,0.0003443839,0.0003877348,0.0002177677,0.0003978478,0.0003974552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002707168,"about_ca_system_score_gemma":0.0001279379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001475305,"about_ca_topic_score_gemma":0.0004942173,"domain_scores_codex":[0.9997696,0.00002997166,0.00002128687,0.00005060148,0.00009006394,0.00003837912],"domain_scores_gemma":[0.9998423,0.00004880896,0.00005092512,0.00002299525,0.00002166079,0.00001324007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004093511,0.000007635009,0.00003229512,0.00003235218,0.000002978023,0.00004814451,0.00001779804,0.0002102284,0.9976224,0.0001676094,0.00003208456,0.001785586],"study_design_scores_gemma":[0.000005140325,0.00004347264,0.0002383062,0.000001320014,0.000004235593,0.00007965855,0.000003665646,0.000449787,0.998426,0.00002618107,0.0007187699,0.000003497794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9681512,0.004454091,0.02128166,0.00008977147,0.0001563003,0.00004848931,0.0001317752,0.0003700487,0.005316735],"genre_scores_gemma":[0.9846789,0.0007468212,0.01083585,0.00004510802,0.00002149275,0.00003110034,0.00005362547,0.00006150337,0.003525537],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008761357,"threshold_uncertainty_score":0.002930939,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2089743750","doi":"10.1016/j.jconrel.2005.02.015","title":"Micelles of methoxy poly(ethylene oxide)-b-poly(ɛ-caprolactone) as vehicles for the solubilization and controlled delivery of cyclosporine A","year":2005,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":210,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Micelle; Ethylene oxide; Caprolactone; Solubility; Chemistry; Drug delivery; Copolymer; Solvent; Drug carrier; Polymer chemistry; Aqueous solution; Nuclear chemistry; Organic chemistry; Polymer","authors":[{"name":"Hamidreza Montazeri Aliabadi","is_ca":true},{"name":"Abdullah Mahmud","is_ca":true},{"name":"Annahita Dehmoobed Sharifabadi","is_ca":true},{"name":"Afsaneh Lavasanifar","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01082898148310875,"gpt":0.2522574228600497,"spread":0.2414284413769409,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004893617,0.0003142237,0.000185782,0.0002327925,0.0001665776,0.0003977593,0.0002190424,0.0003577421,0.0005823245],"category_scores_gemma":[0.0002979613,0.000212375,0.0001732028,0.0001038085,0.0002026681,0.0006033781,0.0002093584,0.0004653712,0.0003524134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003730592,"about_ca_system_score_gemma":0.000356467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005547194,"about_ca_topic_score_gemma":0.0007865566,"domain_scores_codex":[0.9998372,0.00003460766,0.00001612775,0.00002926908,0.00004642062,0.00003644642],"domain_scores_gemma":[0.9998662,0.00002764949,0.00004836964,0.000005933834,0.00002629651,0.00002541338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001488494,0.0000370062,0.00004358654,0.00006196059,0.000007876347,0.00002834848,0.0000216208,0.0002029147,0.9961325,0.0003884118,0.00007334435,0.002853646],"study_design_scores_gemma":[0.00006181677,0.0003417526,0.0002320302,0.000007553316,0.00002372962,0.00006600391,0.000008392192,0.001903385,0.9945958,0.00005454333,0.002699133,0.000005937005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9591469,0.009533159,0.02683466,0.0004252543,0.0002903757,0.0001487605,0.0001249847,0.0002803039,0.003215415],"genre_scores_gemma":[0.9811747,0.003347022,0.01084014,0.0001291662,0.00007813718,0.00008429392,0.0001125024,0.00004577691,0.004188254],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005823245,"threshold_uncertainty_score":0.002706766,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2080815766","doi":"10.1016/j.jconrel.2004.02.022","title":"Strategies for enhancing the immunostimulatory effects of CpG oligodeoxynucleotides","year":2004,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":208,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"","keywords":"CpG Oligodeoxynucleotide; Immune system; CpG site; In vivo; Immunology; TLR9; Biology; Acquired immune system; Cytokine; Innate immune system; Downregulation and upregulation; Cancer research; Gene expression; Biochemistry","authors":[{"name":"George Mutwiri","is_ca":true},{"name":"Anil Nichani","is_ca":true},{"name":"Shawn Babiuk","is_ca":true},{"name":"Lorne A. Babiuk","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.009935497584589966,"gpt":0.2815020574555601,"spread":0.2715665598709701,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004907229,0.001192561,0.00111344,0.0006851935,0.0001678379,0.000572165,0.0008878768,0.0009699428,0.001500476],"category_scores_gemma":[0.0002573492,0.000273355,0.0003073979,0.0005542696,0.0005443941,0.0007225868,0.0004442425,0.001664936,0.001160527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005214926,"about_ca_system_score_gemma":0.0004169291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005478136,"about_ca_topic_score_gemma":0.0009235439,"domain_scores_codex":[0.9998815,0.00001546671,0.00001117093,0.00002307612,0.00004915291,0.00001960231],"domain_scores_gemma":[0.9998956,0.00004096731,0.00001964246,0.000005794513,0.00002534833,0.00001254364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002189312,0.0001833444,0.00008879056,0.006248089,0.00004572207,0.0003828868,0.00005471406,0.001013054,0.2430755,0.005971788,0.004446573,0.7382707],"study_design_scores_gemma":[0.0001778565,0.001015859,0.0009479389,0.001142105,0.0001600805,0.00274256,0.00006860791,0.001113035,0.2474983,0.003093251,0.7419645,0.00007586908],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004121439,0.9819891,0.009496185,0.0003469769,0.000711799,0.0000538298,0.00003286097,0.00006787918,0.003179867],"genre_scores_gemma":[0.01564614,0.9678258,0.009687773,0.0004556761,0.0003424014,0.00009934793,0.0001015418,0.00001419938,0.005827119],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001500476,"threshold_uncertainty_score":0.005019605,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2126858586","doi":"10.1016/j.jconrel.2009.05.009","title":"An injectable drug delivery platform for sustained combination therapy","year":2009,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":206,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Self-healing hydrogels; Swelling; Chemistry; Controlled release; Drug delivery; Pharmacology; Biophysics; Biomedical engineering; Materials science; Polymer chemistry; Medicine; Organic chemistry; Composite material","authors":[{"name":"M. Douglas Baumann","is_ca":true},{"name":"Catherine E. Kang","is_ca":true},{"name":"Jason C. Stanwick","is_ca":true},{"name":"Yuanfei Wang","is_ca":true},{"name":"Howard Kim","is_ca":true},{"name":"Yakov Lapitsky","is_ca":true},{"name":"Molly S. Shoichet","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01696852953684247,"gpt":0.2778565602589972,"spread":0.2608880307221547,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003014797,0.0005463749,0.0004381567,0.0005077336,0.0002624114,0.0006599831,0.0004460587,0.0005214802,0.001814662],"category_scores_gemma":[0.0001839776,0.0003685956,0.0003490517,0.0002406711,0.0002318615,0.00085907,0.0003957048,0.0006264666,0.0006954707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003603399,"about_ca_system_score_gemma":0.0003572609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004821559,"about_ca_topic_score_gemma":0.0008574169,"domain_scores_codex":[0.9998015,0.00002338365,0.00001248647,0.00005301636,0.00007447677,0.00003518044],"domain_scores_gemma":[0.9999298,0.00001439384,0.0000213088,0.000008632646,0.0000128611,0.00001291753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002086277,0.0001176721,0.00007481388,0.0001329058,0.00001974026,0.0002370392,0.00004062513,0.0006888732,0.959874,0.0009671227,0.000448025,0.03719057],"study_design_scores_gemma":[0.0001285101,0.001436741,0.0004601138,0.0000163493,0.0001046097,0.0006151961,0.00001734634,0.008610887,0.9733316,0.0002394152,0.01501145,0.00002772725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7202252,0.01496908,0.239317,0.0008143908,0.001003134,0.0009921017,0.00073362,0.001617148,0.0203282],"genre_scores_gemma":[0.9121497,0.004125528,0.07142693,0.0001566624,0.00009948197,0.0004384623,0.000237731,0.0001121306,0.01125338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001814662,"threshold_uncertainty_score":0.006070673,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2090122150","doi":"10.1016/j.jconrel.2006.09.007","title":"Simultaneous delivery of doxorubicin and GG918 (Elacridar) by new Polymer-Lipid Hybrid Nanoparticles (PLN) for enhanced treatment of multidrug-resistant breast cancer","year":2006,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":205,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Chemosensitizer; Doxorubicin; Pharmacology; Chemistry; Cancer cell; Cytotoxic T cell; Multiple drug resistance; Drug delivery; Clonogenic assay; Chemotherapy; Cancer; Apoptosis; Medicine; Biochemistry; In vitro","authors":[{"name":"Ho Lun Wong","is_ca":true},{"name":"Reina Bendayan","is_ca":true},{"name":"Andrew Mike Rauth","is_ca":true},{"name":"Xiao Yu Wu","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.004367141155643735,"gpt":0.229252685957034,"spread":0.2248855448013902,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001825656,0.000214074,0.0002232043,0.0001243859,0.0001046494,0.0002353552,0.0001533615,0.0002785066,0.000566799],"category_scores_gemma":[0.000110574,0.0001551866,0.0001322068,0.00007728195,0.0001550266,0.0003036793,0.0002152932,0.0002883259,0.0002361248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00029367,"about_ca_system_score_gemma":0.0001462365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003373764,"about_ca_topic_score_gemma":0.0006447131,"domain_scores_codex":[0.9999188,0.00001921505,0.000007167524,0.00002128276,0.00001887028,0.00001466266],"domain_scores_gemma":[0.9999628,0.000007364979,0.00001155954,0.000003846435,0.000004939372,0.000009579241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009689141,0.00001849224,0.00005095492,0.0000277939,0.000003351278,0.00003158831,0.00001169871,0.0001588344,0.9968178,0.00009105874,0.000028211,0.002663282],"study_design_scores_gemma":[0.00003154451,0.0002009889,0.0004073605,0.000002760413,0.00001473297,0.0001346453,0.000005269671,0.001585275,0.9959217,0.00001831388,0.001672961,0.000004332564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890208,0.001354288,0.007776182,0.0001502185,0.00002902387,0.00003528557,0.00005941737,0.00009506639,0.001479913],"genre_scores_gemma":[0.9920594,0.0003838799,0.005443742,0.00003968734,0.00001045474,0.00002665801,0.00004974567,0.00002163989,0.001964815],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000566799,"threshold_uncertainty_score":0.002130747,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2580036324","doi":"10.1016/j.jconrel.2017.01.025","title":"To heat or not to heat: Challenges with clinical translation of thermosensitive liposomes","year":2017,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":204,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Sunnybrook Health Science Centre; Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"Medicine; Clinical trial; Hyperthermia; Liposome; Clinical endpoint; Radiofrequency ablation; Ablation; Hepatocellular carcinoma; Oncology; Surgery; Medical physics; Internal medicine; Nanotechnology; Materials science","authors":[{"name":"Yannan N. Dou","is_ca":true},{"name":"Kullervo Hynynen","is_ca":true},{"name":"Christine Allen","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1364608982451499,"gpt":0.3997213788833806,"spread":0.2632604806382307,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002549176,0.0004834349,0.001124196,0.0006515268,0.0001915993,0.001220304,0.0007531522,0.001496518,0.00137593],"category_scores_gemma":[0.001688078,0.0002520836,0.0005063385,0.0005290403,0.0008379643,0.001723042,0.0006068335,0.002660437,0.0007836964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006034145,"about_ca_system_score_gemma":0.0009121686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006113671,"about_ca_topic_score_gemma":0.001302688,"domain_scores_codex":[0.99959,0.0001001221,0.0000554363,0.0000659846,0.0001469617,0.00004163665],"domain_scores_gemma":[0.9990063,0.0006899364,0.00009933572,0.00002524819,0.0001498994,0.00002928704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001352122,0.00009022486,0.0001211066,0.00785758,0.00004322506,0.000253955,0.0001880729,0.0003221614,0.01206647,0.006360193,0.01259259,0.9599692],"study_design_scores_gemma":[0.00006916888,0.0006100475,0.0008022557,0.004336734,0.0001644044,0.002617253,0.0002385368,0.0005829061,0.01820016,0.004086734,0.9682347,0.00005711816],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007243308,0.9962415,0.000890069,0.001290942,0.0002453605,0.00001177535,0.000008890263,0.00001036173,0.0005769229],"genre_scores_gemma":[0.006881883,0.9890558,0.00141498,0.00112797,0.0003668708,0.00003225138,0.00002442369,0.00001089276,0.001084995],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002549176,"threshold_uncertainty_score":0.0134815,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2050856854","doi":"10.1016/s0168-3659(01)00263-2","title":"N-isopropylacrylamide copolymers for the preparation of pH-sensitive liposomes and polymeric micelles","year":2001,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":197,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Burroughs Wellcome Fund","keywords":"Micelle; Liposome; Copolymer; Chemistry; Polyethylene glycol; Poly(N-isopropylacrylamide); Amphiphile; Polymer; Drug carrier; Critical micelle concentration; Polymer chemistry; Drug delivery; Organic chemistry; Aqueous solution; Biochemistry","authors":[{"name":"Jean‐Christophe Leroux","is_ca":true},{"name":"Emmanuelle Roux","is_ca":true},{"name":"Dorothée Le Garrec","is_ca":true},{"name":"Keelung Hong","is_ca":false},{"name":"Daryl C. Drummond","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.007697455061424685,"gpt":0.2515539003046826,"spread":0.2438564452432579,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004292073,0.0002491185,0.0001536285,0.0002182279,0.0001326614,0.0001943493,0.000177913,0.0003451711,0.0007871114],"category_scores_gemma":[0.0002868973,0.000205595,0.0001626787,0.000102096,0.0001385776,0.0004501096,0.0001843787,0.0004960995,0.0003953835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002720882,"about_ca_system_score_gemma":0.0002175598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002070495,"about_ca_topic_score_gemma":0.0005359892,"domain_scores_codex":[0.999891,0.00002490625,0.00001418814,0.00001720116,0.00003544172,0.00001725082],"domain_scores_gemma":[0.9998981,0.00003392618,0.00002720248,0.00001140591,0.00001382283,0.00001558882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006398107,0.00001926516,0.00003771637,0.00005187194,0.000002727138,0.0000337262,0.00001461398,0.0001032441,0.9963085,0.0003117952,0.00005714098,0.002995294],"study_design_scores_gemma":[0.00001095691,0.00004658333,0.000185593,0.000003469342,0.000004815308,0.00008465548,0.000001978937,0.0005088721,0.9978861,0.00003363309,0.001230614,0.000002773759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9136659,0.01232684,0.06744368,0.0004956455,0.000141565,0.0002008755,0.0002356576,0.0004311524,0.00505871],"genre_scores_gemma":[0.9693736,0.003102606,0.02193404,0.00009706481,0.00003273184,0.00008821987,0.000234576,0.00005724858,0.005079926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007871114,"threshold_uncertainty_score":0.002633154,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2035757734","doi":"10.1016/j.jconrel.2004.09.014","title":"Enhancement of T helper type 1 immune responses against hepatitis B virus core antigen by PLGA nanoparticle vaccine delivery","year":2004,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":190,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"HBcAg; PLGA; Immune system; Antigen; Immunization; Adjuvant; Hepatitis B virus; Virology; Immunology; Medicine; Virus; HBsAg; Materials science; Nanoparticle; Nanotechnology","authors":[{"name":"Carrie S.W. Chong","is_ca":true},{"name":"Min Cao","is_ca":true},{"name":"Winnie W. Wong","is_ca":true},{"name":"Karl P. Fischer","is_ca":true},{"name":"William R. Addison","is_ca":true},{"name":"Glen S. Kwon","is_ca":true},{"name":"D. Lorne Tyrrell","is_ca":true},{"name":"John Samuel","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01511144614522121,"gpt":0.2719411451385952,"spread":0.256829698993374,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001987983,0.0003266282,0.0001910158,0.0001528211,0.0001303821,0.0002292799,0.0001609291,0.0003402164,0.001047613],"category_scores_gemma":[0.0002112123,0.0001630615,0.0002046758,0.00005161026,0.0002012435,0.0002888982,0.0001622239,0.0004843177,0.0002883375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000214407,"about_ca_system_score_gemma":0.0001873626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003986366,"about_ca_topic_score_gemma":0.0004335243,"domain_scores_codex":[0.99989,0.0000251423,0.000005810617,0.00001906726,0.00001885371,0.00004116792],"domain_scores_gemma":[0.999938,0.0000254747,0.000009957938,0.000006870522,0.00001057323,0.000008980767],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002963622,0.00007131814,0.00005864172,0.00004063085,0.000002884809,0.00003074868,0.00002529442,0.0001306421,0.9961452,0.0001039632,0.00004193133,0.003052333],"study_design_scores_gemma":[0.00006629847,0.001091252,0.0005026438,0.000005379795,0.00001305741,0.0001067113,0.00001451382,0.001145563,0.996033,0.00005656172,0.0009620299,0.00000293777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938909,0.0007851432,0.003710544,0.00008437502,0.00003698057,0.00005410636,0.00002986453,0.00004963616,0.001358487],"genre_scores_gemma":[0.9962471,0.0002878667,0.001510705,0.0000415576,0.00001331979,0.00003539736,0.00004838822,0.00001234446,0.00180331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001047613,"threshold_uncertainty_score":0.003504634,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1577089616","doi":"10.1016/j.jconrel.2015.08.060","title":"Drug delivery, cell-based therapies, and tissue engineering approaches for spinal cord injury","year":2015,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":187,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"International Collaboration On Repair Discoveries; University of British Columbia","funders":"National Institute of Biomedical Imaging and Bioengineering; National Institute of Neurological Disorders and Stroke","keywords":"Medicine; Spinal cord injury; Spinal cord; Neuroscience; Pathological; Bioinformatics; Pathology; Psychology; Biology","authors":[{"name":"Shushi Kabu","is_ca":false},{"name":"Yue Gao","is_ca":false},{"name":"Brian K. Kwon","is_ca":true},{"name":"Vinod Labhasetwar","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07546920424434173,"gpt":0.3254099863181952,"spread":0.2499407820738535,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006341279,0.001020371,0.001524712,0.002554803,0.0002978494,0.0009634725,0.001009716,0.001138614,0.002505412],"category_scores_gemma":[0.0004852916,0.000365903,0.0005344012,0.001936429,0.0006862984,0.001293306,0.0008283628,0.001690797,0.001314075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004812989,"about_ca_system_score_gemma":0.000657284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009754137,"about_ca_topic_score_gemma":0.002263322,"domain_scores_codex":[0.9997959,0.00001960796,0.00002855603,0.00003309482,0.0001019751,0.00002080063],"domain_scores_gemma":[0.9998061,0.00008734711,0.00004395282,0.000005592095,0.00003960821,0.00001748626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0001049988,0.0001505823,0.00008720437,0.01982649,0.00008592234,0.0002250291,0.0000583319,0.0004871118,0.01291684,0.004195392,0.01455947,0.9473027],"study_design_scores_gemma":[0.00004495853,0.0002689626,0.0008182422,0.002799201,0.0001767822,0.001887573,0.00005944871,0.0003607402,0.004542529,0.002350493,0.9866447,0.00004641284],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002096328,0.9986091,0.0003209677,0.00008821,0.0001209323,0.000007103054,0.00001310611,0.000007133956,0.0006237963],"genre_scores_gemma":[0.001145189,0.9973478,0.0004805913,0.0001038992,0.0001263044,0.00000952151,0.00001925453,0.000001965793,0.0007655405],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002554803,"threshold_uncertainty_score":0.008381486,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2053958243","doi":"10.1016/j.jconrel.2014.06.012","title":"Disulfide-containing parenteral delivery systems and their redox-biological fate","year":2014,"lang":"en","type":"review","venue":"Journal of Controlled Release","topic":"Protein Interaction Studies and Fluorescence Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":187,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Scientific Systems Company, Incorporated","keywords":"Redox; Chemistry; Disulfide bond; Biochemistry; Organic chemistry","authors":[{"name":"Lorine Brülisauer","is_ca":false},{"name":"Marc A. Gauthier","is_ca":true},{"name":"Jean‐Christophe Leroux","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02228491174204686,"gpt":0.2957773229161402,"spread":0.2734924111740934,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006127993,0.0008855129,0.001051231,0.001037711,0.0001423967,0.0006917782,0.000696673,0.000796903,0.001260384],"category_scores_gemma":[0.0004435735,0.0002719373,0.0003460251,0.001026435,0.0006173439,0.0008937317,0.0004807894,0.001161491,0.0007714439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003835782,"about_ca_system_score_gemma":0.000328703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002697529,"about_ca_topic_score_gemma":0.000430378,"domain_scores_codex":[0.9998228,0.00002698624,0.00002126383,0.00003493058,0.00007533962,0.00001875351],"domain_scores_gemma":[0.9998227,0.00008815336,0.0000417317,0.000008078371,0.00003005283,0.000009378495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001663496,0.000146717,0.0001439308,0.009689677,0.0000593861,0.0002576433,0.00006370068,0.0005418412,0.04376874,0.00518187,0.007528429,0.9324517],"study_design_scores_gemma":[0.0000503363,0.0007740029,0.001274695,0.001783487,0.0002038854,0.003708329,0.00008500763,0.0007184196,0.05422309,0.002709505,0.9344067,0.00006261307],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001851292,0.9944404,0.001762734,0.0001604963,0.0001925525,0.00001333151,0.00002529727,0.00001794025,0.001536039],"genre_scores_gemma":[0.008689312,0.9865569,0.001860156,0.0001713219,0.0001778909,0.00002740876,0.00004896261,0.000006658144,0.002461379],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001260384,"threshold_uncertainty_score":0.004216373,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2073773999","doi":"10.1016/j.jconrel.2005.01.010","title":"Liposome-encapsulated vincristine, vinblastine and vinorelbine: A comparative study of drug loading and retention","year":2005,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Analytical Chemistry and Chromatography","field":"Chemistry","cited_by":187,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Inimex Pharmaceuticals (Canada); University of British Columbia","funders":"Canadian Institutes of Health Research; Uppsala Universitet","keywords":"Vinca; Vinorelbine; Vinblastine; Liposome; Ionophore; Chemistry; Pharmacology; Drug; Dosage form; In vivo; Vincristine; Vesicle; Chromatography; Membrane; Biochemistry; Medicine; Chemotherapy; Biology; Internal medicine","authors":[{"name":"Igor V. Zhigaltsev","is_ca":true},{"name":"Norbert Maurer","is_ca":true},{"name":"Quet-Fah Akhong","is_ca":true},{"name":"Robert D. Leone","is_ca":true},{"name":"Esther Leng","is_ca":true},{"name":"Jinfang Wang","is_ca":true},{"name":"Sean C. Semple","is_ca":true},{"name":"Pieter R. Cullis","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.008924317936427381,"gpt":0.2422153631733882,"spread":0.2332910452369608,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003190262,0.0002403688,0.0003808113,0.0001736479,0.0001688726,0.0004235937,0.0002231726,0.0003484911,0.0007914908],"category_scores_gemma":[0.0004296997,0.0001904059,0.000189765,0.0002046801,0.0002945749,0.0007243321,0.0001637803,0.0003176038,0.0002732419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004035727,"about_ca_system_score_gemma":0.000295969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001818374,"about_ca_topic_score_gemma":0.001335634,"domain_scores_codex":[0.9998646,0.00002368761,0.00001090444,0.0000314313,0.00002759939,0.00004175001],"domain_scores_gemma":[0.999785,0.00009003037,0.0000378062,0.00002057631,0.00003898566,0.00002760045],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006803479,0.00003273468,0.0001197344,0.00004025134,0.000008533377,0.00003039046,0.00003465992,0.0001281567,0.9966265,0.00007317932,0.00002983945,0.002195715],"study_design_scores_gemma":[0.00001450185,0.0003428731,0.001186126,0.000003223154,0.00002103838,0.00004757714,0.00001661542,0.000961301,0.9968875,0.000009309108,0.0005043432,0.000005559104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959738,0.001322309,0.001706413,0.00003105302,0.00001486902,0.00001811739,0.0001341561,0.00003662728,0.0007627241],"genre_scores_gemma":[0.9955425,0.0008709245,0.001380927,0.00001799437,0.000006186513,0.0000174698,0.0001793091,0.00003234809,0.001952381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001818374,"threshold_uncertainty_score":0.003615558,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}