{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":53,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":53,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"38507e7e855a","filters":{"venue":"Mini-Reviews in Medicinal Chemistry"}},"results":[{"id":"W2137786090","doi":"10.2174/138955711796268750","title":"Caffeic Acid, A Versatile Pharmacophore: An Overview","year":2011,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Bee Products Chemical Analysis","field":"Agricultural and Biological Sciences","cited_by":176,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Moncton","funders":"Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Pharmacophore; Caffeic acid; Caffeic acid phenethyl ester; Chemistry; Biological activity; Combinatorial chemistry; Computational biology; Biochemistry; Biology; In vitro; Antioxidant","authors":[{"name":"Mohamed Touaibia","is_ca":true},{"name":"Jacques Jean‐François","is_ca":true},{"name":"Jérémie A. Doiron","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1738708136801388,"gpt":0.362684528894458,"spread":0.1888137152143191,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002659746,0.0007307362,0.0008375515,0.001747684,0.0002386837,0.0006011635,0.0005106389,0.0006630086,0.00221616],"category_scores_gemma":[0.0001634242,0.0003029754,0.0002878277,0.001380518,0.0003061249,0.001146596,0.0003792378,0.0008542389,0.001507357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005304577,"about_ca_system_score_gemma":0.0004773397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009082729,"about_ca_topic_score_gemma":0.001405325,"domain_scores_codex":[0.9999175,0.000009398797,0.000008346081,0.00002085787,0.00003246702,0.00001142516],"domain_scores_gemma":[0.999935,0.0000232595,0.0000130981,0.000002311236,0.00001517557,0.00001114708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00011972,0.0001709867,0.0002387685,0.0128068,0.00007381871,0.000582571,0.00009209781,0.001135492,0.04265505,0.006565284,0.01034668,0.9252127],"study_design_scores_gemma":[0.00002915851,0.0003241124,0.001048554,0.000782054,0.00007574851,0.002260791,0.00005178256,0.0004293525,0.009826412,0.001680711,0.983465,0.00002624708],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001638877,0.9931269,0.001274042,0.0002532026,0.0001067389,0.00001746723,0.00004377985,0.00002519833,0.003513757],"genre_scores_gemma":[0.007622506,0.9893525,0.001174962,0.000160135,0.0001460051,0.00001469075,0.00007898494,0.000003194823,0.001447008],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00221616,"threshold_uncertainty_score":0.007413805,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2980759863","doi":"10.2174/1389557519666191014142448","title":"Synthesis and Biological Activity of Hydrazones and Derivatives: A Review","year":2019,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":141,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Combinatorial chemistry; Drug discovery; Chemistry; Biochemistry","authors":[{"name":"Juliana de Oliveira Carneiro Brum","is_ca":false},{"name":"Tanos C. C. França","is_ca":true},{"name":"Steven R. LaPlante","is_ca":true},{"name":"José Daniel Figueroa‐Villar","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1232847144110934,"gpt":0.3532031108191077,"spread":0.2299183964080143,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004126708,0.0009678265,0.001048123,0.002153479,0.000374355,0.0008232531,0.0006933243,0.0006967258,0.005462572],"category_scores_gemma":[0.0004964413,0.0004342216,0.0005475325,0.002120711,0.0003823936,0.001247767,0.0005096622,0.001093359,0.002428309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004381761,"about_ca_system_score_gemma":0.0008471544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006539836,"about_ca_topic_score_gemma":0.00130425,"domain_scores_codex":[0.9998276,0.00002491536,0.00002431727,0.00003821439,0.00006203033,0.00002288758],"domain_scores_gemma":[0.9998257,0.00006917866,0.00004139166,0.000007403049,0.0000426244,0.00001380349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001436093,0.0002014949,0.0002231596,0.07576592,0.0001458992,0.000558654,0.0001606422,0.001172257,0.02681342,0.007958964,0.02815223,0.8587038],"study_design_scores_gemma":[0.00001175043,0.0002291479,0.0004919101,0.002601928,0.000124157,0.001202685,0.00005147645,0.0001508334,0.006335608,0.001508139,0.9872623,0.00003011775],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005044282,0.9969347,0.0003401242,0.0001485388,0.0001929078,0.00001222688,0.00005761588,0.00001519172,0.001794312],"genre_scores_gemma":[0.002226037,0.995985,0.0004453859,0.0001233857,0.0001223778,0.00001243585,0.00005824395,0.000003209083,0.0010239],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005462572,"threshold_uncertainty_score":0.01827407,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2131908174","doi":"10.2174/138955711795906941","title":"Anti-Inflammatory Properties of Antipsychotics Via Microglia Modulations: Are Antipsychotics a &amp;#x2018;Fire Extinguisher&amp;#x2019; in the Brain of Schizophrenia?","year":2011,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":124,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"","keywords":"Schizophrenia (object-oriented programming); Dopamine; Microglia; Neuroscience; Antipsychotic; Dopamine receptor D2; Medicine; Psychosis; Dopamine hypothesis of schizophrenia; Dementia; Psychology; Psychiatry; Inflammation; Internal medicine; Disease","authors":[{"name":"Takahiro A. Kato","is_ca":false},{"name":"Akira Monji","is_ca":false},{"name":"Yoshito Mizoguchi","is_ca":false},{"name":"Sadayuki Hashioka","is_ca":true},{"name":"Hideki Horikawa","is_ca":false},{"name":"Yoshihiro Seki","is_ca":false},{"name":"Mina Kasai","is_ca":false},{"name":"Hideo Utsumi","is_ca":false},{"name":"Shigenobu Kanba","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1197458027990015,"gpt":0.3342569643533351,"spread":0.2145111615543336,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002134243,0.0004199446,0.0004472705,0.0004764986,0.0002290874,0.0005195462,0.0002545446,0.0006509186,0.001691347],"category_scores_gemma":[0.0001879597,0.0001053206,0.0002869088,0.0003107699,0.0002725036,0.000539592,0.0002451981,0.0007895728,0.0008983372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003165691,"about_ca_system_score_gemma":0.0004452163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008122822,"about_ca_topic_score_gemma":0.002633767,"domain_scores_codex":[0.9999051,0.0000207826,0.00001941333,0.00001158046,0.00002902024,0.00001415586],"domain_scores_gemma":[0.9999154,0.0000121152,0.00002433525,0.000002445377,0.00003184582,0.00001393021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000563647,0.0002081157,0.001088712,0.008955713,0.00009213947,0.001206145,0.0002606788,0.0003591228,0.0518923,0.004564205,0.02393283,0.9068764],"study_design_scores_gemma":[0.0001598819,0.002197745,0.01217967,0.002428233,0.0003114565,0.005851088,0.0002983605,0.0006423884,0.02202284,0.004705061,0.9490994,0.0001039015],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006246307,0.9868712,0.0003740132,0.002282894,0.000495553,0.00001567768,0.00006620133,0.00003477464,0.003613322],"genre_scores_gemma":[0.02785353,0.9650828,0.0007517092,0.001666095,0.000925888,0.0000276917,0.00008186294,0.000009623892,0.003600742],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001691347,"threshold_uncertainty_score":0.00565809,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2059858120","doi":"10.2174/138955707779317849","title":"Currently Available Drugs for the Treatment of Obesity: Sibutramine and Orlistat","year":2006,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Pharmacology and Obesity Treatment","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Sibutramine; Orlistat; Weight loss; Medicine; Obesity; Adverse effect; Management of obesity; Pharmacotherapy; Anti obesity; Pharmacology; Internal medicine","authors":[{"name":"Jean‐Philippe Chaput","is_ca":false},{"name":"Sylvie St‐Pierre","is_ca":false},{"name":"André Ulmann Dominique Tremblay","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07298915106032712,"gpt":0.3919651000763007,"spread":0.3189759490159736,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002448311,0.001055823,0.001312424,0.00213213,0.0002911238,0.0005844056,0.0008127661,0.0009051317,0.007400142],"category_scores_gemma":[0.0002253673,0.0002125172,0.0004368088,0.001800722,0.0003380686,0.0008648612,0.000447231,0.001746081,0.006934453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003322981,"about_ca_system_score_gemma":0.0005337918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007293074,"about_ca_topic_score_gemma":0.001847634,"domain_scores_codex":[0.9998711,0.00001527082,0.00001579324,0.00002490946,0.00005937885,0.00001349325],"domain_scores_gemma":[0.9998897,0.00003239502,0.00002796145,0.000004130356,0.00002806163,0.00001766208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000177706,0.0002072247,0.0001376513,0.008469102,0.00007270839,0.0002342905,0.0000376699,0.000159358,0.006107026,0.00101817,0.0262805,0.9570985],"study_design_scores_gemma":[0.0001373639,0.0003256595,0.002040859,0.002366419,0.0001868386,0.004027108,0.00005774175,0.0001486323,0.002534125,0.001391326,0.986759,0.00002488093],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004666492,0.9956102,0.0003427523,0.0003060965,0.0003417587,0.00002228585,0.00004455072,0.00003985618,0.002825814],"genre_scores_gemma":[0.00175353,0.9934705,0.0006210288,0.0004183608,0.0003268277,0.0000276867,0.00009178324,0.000003924117,0.003286295],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007400142,"threshold_uncertainty_score":0.02475601,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2051472909","doi":"10.2174/138955707782795610","title":"Glycodendrimers as Anti-Adhesion Drugs Against Type 1 Fimbriated E. coli Uropathogenic Infections","year":2007,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Glycan; Glycoconjugate; Bacterial adhesin; Microbiology; Fimbria; Antimicrobial; Chemistry; Adhesion; Antibiotics; Drug; Escherichia coli; Glycoprotein; Biology; Biochemistry; Pharmacology; Gene","authors":[{"name":"Mohamed Touaibia","is_ca":true},{"name":"René Roy","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04695131901534871,"gpt":0.3918499233146419,"spread":0.3448986042992931,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002215528,0.0006714208,0.000824091,0.001225266,0.0001973543,0.0004445122,0.0005600485,0.0007188024,0.002282281],"category_scores_gemma":[0.0001538572,0.0002307944,0.000299588,0.001103443,0.0002269451,0.0006046339,0.0002732969,0.0008460697,0.002211971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003321046,"about_ca_system_score_gemma":0.0002513696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000382598,"about_ca_topic_score_gemma":0.0009508083,"domain_scores_codex":[0.9999048,0.00001345077,0.000008003482,0.00001382248,0.00004817217,0.00001182102],"domain_scores_gemma":[0.9999543,0.00001419197,0.00001015573,0.000001908223,0.00001226541,0.000007104074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001447414,0.0002416432,0.0001266767,0.008622854,0.00008931695,0.0004388599,0.00007757683,0.001007996,0.06161739,0.004388047,0.01448402,0.9087608],"study_design_scores_gemma":[0.00006496633,0.000535938,0.001294811,0.0009022569,0.00009149855,0.001791555,0.00004435933,0.0003952536,0.02145235,0.001223567,0.97217,0.00003332859],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002986415,0.991538,0.0008676174,0.0001572385,0.0002795746,0.00002964715,0.00003796473,0.00004614969,0.004057317],"genre_scores_gemma":[0.007262128,0.9864964,0.00152501,0.0002615509,0.0001381385,0.00003113119,0.00007648808,0.000004759852,0.0042043],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002282281,"threshold_uncertainty_score":0.007634997,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2546732439","doi":"10.2174/1389557516666161004162133","title":"Cannabis: A Treasure Trove or Pandora's Box?","year":2016,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Agriculture and Agri-Food Canada; Eötvös Loránd Tudományegyetem; Medizinische Universität Wien; Fundação para a Ciência e a Tecnologia; Universidade de Coimbra; Magyar Tudományos Akadémia; Universität Wien","keywords":"Cannabis; Cannabinoid; Legalization; Treasure; Forensic toxicology; Psychiatry; Medicine; Biology; Chemistry; Genetics; Geography","authors":[{"name":"Katalin Solymosi","is_ca":false},{"name":"Attila Köfalvi","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06343502386468046,"gpt":0.3969579235646954,"spread":0.333522899700015,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005222238,0.0004562809,0.0006277329,0.001411502,0.002561797,0.002942099,0.000615011,0.002053903,0.01445289],"category_scores_gemma":[0.001596764,0.0002014107,0.0003399042,0.001496907,0.004472219,0.005076602,0.001506834,0.003037325,0.00391077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001886814,"about_ca_system_score_gemma":0.003178574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009174827,"about_ca_topic_score_gemma":0.01449177,"domain_scores_codex":[0.9995652,0.00008695808,0.00003045217,0.00008199817,0.0001736916,0.00006166645],"domain_scores_gemma":[0.999465,0.0002150815,0.00005040437,0.00004203975,0.0001360123,0.00009134471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003095996,0.00005405008,0.001943045,0.004255109,0.00006813205,0.001484353,0.003193012,0.0001720027,0.00494923,0.1196644,0.2583779,0.6055291],"study_design_scores_gemma":[0.000003226212,0.00002209901,0.0006481093,0.000914472,0.00001188776,0.0007276434,0.001045904,0.00003089587,0.000363504,0.01132137,0.9848924,0.00001850183],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00599299,0.7630593,0.002240343,0.1412766,0.01957037,0.00004498182,0.0006884562,0.0003315245,0.06679534],"genre_scores_gemma":[0.06971017,0.7803165,0.003918591,0.05703705,0.0147388,0.00005140629,0.0008271353,0.0002456987,0.07315462],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01445289,"threshold_uncertainty_score":0.0483498,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2161909900","doi":"10.2174/138955708784223512","title":"Polyphenols as Potential Inhibitors of Amyloid Aggregation and Toxicity:Possible Significance to Alzheimers Disease","year":2008,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; Institut National de la Santé et de la Recherche Médicale","keywords":"Disease; Alzheimer's disease; Amyloid (mycology); Amyloid β; Polyphenol; Amyloid beta; Toxicity; Medicine; Pharmacology; Chemistry; Biochemistry; Internal medicine; Pathology; Antioxidant","authors":[{"name":"Stéphane Bastianetto","is_ca":true},{"name":"Slavica Krantic","is_ca":false},{"name":"Rémi Quirion","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04235191725474031,"gpt":0.3578021533500633,"spread":0.315450236095323,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002041669,0.0006719163,0.0009176129,0.001176335,0.0002262203,0.0005920251,0.0004826176,0.0006524486,0.002487593],"category_scores_gemma":[0.000172128,0.0001906926,0.0003227644,0.001069244,0.0002423211,0.00062858,0.0003137418,0.0008300185,0.001844254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002646576,"about_ca_system_score_gemma":0.0003320733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003771831,"about_ca_topic_score_gemma":0.0008222453,"domain_scores_codex":[0.9999257,0.00001278665,0.000007994877,0.00001320903,0.00002973099,0.00001063408],"domain_scores_gemma":[0.9999412,0.00001796844,0.0000127969,0.000002689015,0.00001695372,0.000008442214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000176157,0.0002245775,0.0002541188,0.01303293,0.0001069263,0.0005654562,0.00007432186,0.0004901907,0.03472147,0.003439863,0.01017171,0.9367422],"study_design_scores_gemma":[0.00008669307,0.000530188,0.002499813,0.001777127,0.000205632,0.003300661,0.00008723064,0.0002723872,0.01494508,0.002832308,0.9734254,0.0000374959],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001465426,0.9962923,0.0002747293,0.0001387907,0.0001550337,0.000009145694,0.00001905656,0.00001348921,0.001632063],"genre_scores_gemma":[0.005111991,0.9922693,0.0005131201,0.0001404874,0.0001384083,0.00001241731,0.00003931503,0.000002286385,0.001772696],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002487593,"threshold_uncertainty_score":0.008321822,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2137110320","doi":"10.2174/138955707779802642","title":"Cytotoxic Thiol Alkylators","year":2007,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Synthesis and Reactivity of Sulfur-Containing Compounds","field":"Chemistry","cited_by":74,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Cytotoxic T cell; Thiol; Chemistry; Biology; Computational biology; Cell biology; Biochemistry; In vitro","authors":[{"name":"Hari N. Pati","is_ca":true},{"name":"Umashankar Das","is_ca":false},{"name":"Rajendra K. Sharma","is_ca":false},{"name":"Jonathan R. Dimmock","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08974212281996294,"gpt":0.3653887187969334,"spread":0.2756465959769705,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001201699,0.000683252,0.0005092887,0.000859269,0.0001973963,0.0002929832,0.000403154,0.0004300204,0.003670876],"category_scores_gemma":[0.0001056517,0.0001316841,0.000201118,0.0005301166,0.0001614968,0.0003257798,0.0002934783,0.0005652129,0.00253039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003557217,"about_ca_system_score_gemma":0.0002320459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003819775,"about_ca_topic_score_gemma":0.0008132217,"domain_scores_codex":[0.9999194,0.000008133235,0.000006047359,0.0000176087,0.00003493582,0.00001377423],"domain_scores_gemma":[0.9999549,0.0000100576,0.000009557221,0.000003445646,0.00001472729,0.000007278222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001467392,0.0001815484,0.0003237861,0.006338439,0.00005412021,0.0005818363,0.0001010596,0.0007250768,0.2129087,0.004965114,0.01299212,0.7606815],"study_design_scores_gemma":[0.00003166031,0.0005311804,0.001292569,0.0004728298,0.0000684125,0.002806809,0.00005085324,0.0002011776,0.1527674,0.0008550136,0.8409027,0.00001947619],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0109799,0.9655082,0.001789401,0.0002431619,0.0004121943,0.00005644797,0.0001364311,0.0001267396,0.0207476],"genre_scores_gemma":[0.05209961,0.9169188,0.001698338,0.0003772719,0.0002456246,0.00007977503,0.0004102681,0.00001481177,0.02815552],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003670876,"threshold_uncertainty_score":0.01228029,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2152347074","doi":"10.2174/138955706776073402","title":"Rho-Kinase as a Drug Target for the Treatment of Airway Hyperresponsiveness in Asthma","year":2006,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Health Canada","keywords":"Fasudil; Bronchoconstriction; Airway hyperresponsiveness; Medicine; Asthma; Airway; Immunology; Bronchial hyperresponsiveness; Drug; Inflammation; Rho-associated protein kinase; Pharmacology; Kinase; Anesthesia; Internal medicine; Respiratory disease; Lung; Biology","authors":[{"name":"Reinoud Gosens","is_ca":false},{"name":"Dedmer Schaafsma","is_ca":false},{"name":"S.Adriaan Nelemans","is_ca":false},{"name":"Andrew J. Halayko","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03651750191007336,"gpt":0.3599891177630786,"spread":0.3234716158530052,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004521309,0.0006551298,0.001555589,0.00147738,0.000307768,0.0006222753,0.000633698,0.0009121982,0.004324803],"category_scores_gemma":[0.0002219289,0.0002363532,0.0004236107,0.001206463,0.0003640828,0.0009836855,0.0003993977,0.001238658,0.00342419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003617526,"about_ca_system_score_gemma":0.000628592,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000393394,"about_ca_topic_score_gemma":0.001232749,"domain_scores_codex":[0.9998747,0.00002453398,0.00001524739,0.00002137547,0.00004715606,0.00001693067],"domain_scores_gemma":[0.9998983,0.00003421681,0.00002165804,0.00000467023,0.00002605839,0.00001503093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002563669,0.0002204125,0.0001847152,0.0126075,0.0001139781,0.0006209949,0.00009553399,0.0005630612,0.02012603,0.004011675,0.02111297,0.9400868],"study_design_scores_gemma":[0.0001413263,0.0006948815,0.00145284,0.001687293,0.0001651891,0.003212228,0.0000910605,0.0002455417,0.004680657,0.00227302,0.9853224,0.00003352358],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000814972,0.9961911,0.0003467093,0.0003963116,0.0002464611,0.00001744922,0.0000245887,0.00002156013,0.001940803],"genre_scores_gemma":[0.002924053,0.9935515,0.000748596,0.0003273713,0.0002256029,0.00002062106,0.00005611354,0.000003374299,0.002142744],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004324803,"threshold_uncertainty_score":0.0144679,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2320624260","doi":"10.2174/1389557043403765","title":"Predicting Synthetic Accessibility: Application in Drug Discovery and Development","year":2004,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Pharmaceutical Economics and Policy","field":"Economics, Econometrics and Finance","cited_by":64,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Guelph","funders":"","keywords":"Drug discovery; Prioritization; Computer science; Process (computing); Retrosynthetic analysis; Synthetic data; Data science; Risk analysis (engineering); Artificial intelligence; Management science; Engineering; Bioinformatics; Medicine; Biology; Chemistry","authors":[{"name":"Junaid Baber","is_ca":true},{"name":"Miklós Fehér","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08561049642649078,"gpt":0.3521774650157009,"spread":0.2665669685892101,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003538054,0.001261388,0.001914458,0.003083694,0.0002422686,0.001621206,0.001299967,0.001229595,0.003329744],"category_scores_gemma":[0.01157799,0.0004082472,0.0007911797,0.003814784,0.000920761,0.002078716,0.0007285209,0.001120219,0.001557773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000998761,"about_ca_system_score_gemma":0.001254286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002142388,"about_ca_topic_score_gemma":0.002393631,"domain_scores_codex":[0.9984737,0.000692138,0.00009754983,0.000154192,0.0005412217,0.00004108762],"domain_scores_gemma":[0.9938059,0.004832502,0.0007230336,0.0001355484,0.0004422105,0.0000608191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006033853,0.00006843853,0.002948942,0.00743762,0.0002501492,0.00009654225,0.0000562952,0.02667057,0.001285701,0.01865147,0.006118588,0.9363554],"study_design_scores_gemma":[0.0001652511,0.001595465,0.02663024,0.01108948,0.001152958,0.003047046,0.0005532071,0.1313486,0.01497919,0.2638616,0.5451738,0.0004031301],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005976922,0.9189378,0.06500162,0.001959636,0.0003348922,0.00009569976,0.0003646766,0.0002080641,0.007120662],"genre_scores_gemma":[0.04754736,0.926052,0.02420313,0.0002318533,0.000354681,0.00010898,0.0003719862,0.00001908024,0.00111097],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003538054,"threshold_uncertainty_score":0.01871127,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2320665292","doi":"10.2174/138955711795906888","title":"Antidepressants and Neuroinflammation: Can Antidepressants Calm Glial Rage Down?","year":2011,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":47,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"","keywords":"Neuroinflammation; Astrogliosis; Microglia; Neuroscience; Antidepressant; Medicine; Gliosis; Astrocyte; Inflammation; Pharmacology; Immunology; Biology; Central nervous system; Hippocampus","authors":[{"name":"Sadayuki Hashioka","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08061159292120237,"gpt":0.3306726767791806,"spread":0.2500610838579782,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000352928,0.0007436529,0.001187117,0.001087646,0.0002600637,0.0007949273,0.0007705593,0.001307409,0.004069376],"category_scores_gemma":[0.0003440178,0.0002255501,0.0004038302,0.001139529,0.0003656759,0.001202135,0.0005141522,0.001271402,0.002813005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005087063,"about_ca_system_score_gemma":0.0006809267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009027756,"about_ca_topic_score_gemma":0.002788945,"domain_scores_codex":[0.9999013,0.00001830846,0.00001762471,0.00001565247,0.00003318511,0.00001393629],"domain_scores_gemma":[0.9998862,0.0000417764,0.00002071603,0.000004368951,0.00003287305,0.00001403989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001252725,0.00006448402,0.0001592574,0.0122793,0.00009915922,0.0003252426,0.00006400998,0.0001818046,0.002994682,0.002419146,0.03251034,0.9487773],"study_design_scores_gemma":[0.00006166652,0.0002007618,0.001964973,0.004071258,0.0001766062,0.002423419,0.0001469968,0.0001462352,0.001458272,0.003856929,0.9854642,0.0000286319],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001075477,0.9990081,0.00004203152,0.0002884661,0.0001226623,0.000002729223,0.000009478187,0.000004065134,0.0004149584],"genre_scores_gemma":[0.0006734164,0.9982647,0.0001013491,0.0001986835,0.0001595854,0.000004136527,0.0000196326,8.161447e-7,0.0005777046],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004069376,"threshold_uncertainty_score":0.01361346,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2153855936","doi":"10.2174/138955709788681663","title":"Involvement of MAPK Signalling in Human Villous Trophoblast Differentiation","year":2009,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université du Québec à Montréal; Institut National de la Recherche Scientifique; Armand Frappier Museum","funders":"","keywords":"Trophoblast; Cell biology; Signalling; MAPK/ERK pathway; Chemistry; Biology; Signal transduction; Placenta; Pregnancy; Genetics; Fetus","authors":[{"name":"Cathy Vaillancourt","is_ca":true},{"name":"Dave Lanoix","is_ca":true},{"name":"Frédérique Le Bellego","is_ca":true},{"name":"Georges Daoud","is_ca":false},{"name":"J. Lafond","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06477021005393231,"gpt":0.3466253635871335,"spread":0.2818551535332012,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002171192,0.0004538939,0.0006254778,0.0008192877,0.0001460017,0.000436535,0.0002997055,0.0004645979,0.001741091],"category_scores_gemma":[0.0001580799,0.0001511589,0.0002644226,0.0005757943,0.0001767569,0.0004697147,0.0003017762,0.0005416909,0.001170521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002925218,"about_ca_system_score_gemma":0.0004299384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003930063,"about_ca_topic_score_gemma":0.0006480159,"domain_scores_codex":[0.9999074,0.00001523734,0.00001527502,0.00001523949,0.00003415823,0.00001264671],"domain_scores_gemma":[0.9999493,0.00001865177,0.00001193639,0.000001538162,0.00001434415,0.00000428083],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003190449,0.00009641448,0.0005317437,0.02169166,0.0001176934,0.001408207,0.0001568826,0.0006430716,0.09602887,0.003458788,0.00744423,0.8681034],"study_design_scores_gemma":[0.00007913973,0.0006204682,0.007131861,0.0026874,0.0002870991,0.009350247,0.0002439424,0.0004340068,0.05185205,0.003102041,0.9241597,0.00005200579],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002670624,0.9943706,0.0003816007,0.0001729085,0.0001151954,0.00001021195,0.00004664353,0.00001425141,0.002217893],"genre_scores_gemma":[0.008780701,0.9894664,0.0004354247,0.00008509403,0.00006280283,0.000009648106,0.00005981646,0.000001445918,0.001098577],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001741091,"threshold_uncertainty_score":0.005824506,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2136967060","doi":"10.2174/1389557053544056","title":"Medicinal Chemistry and Properties of 1,2,4-Thiadiazoles","year":2005,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":46,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Apotex (Canada)","funders":"","keywords":"Cysteine; Pharmacophore; Thiadiazoles; Chemistry; Moiety; Thiol; Cysteine Proteinase Inhibitors; Stereochemistry; Cystamine; Electrophile; Enzyme; Covalent bond; Cathepsin; Combinatorial chemistry; Biochemistry; Medicinal chemistry; Organic chemistry","authors":[{"name":"Tim F. Tam","is_ca":true},{"name":"Régis Leung-Toung","is_ca":false},{"name":"Wanren Li","is_ca":false},{"name":"Michael Spino","is_ca":false},{"name":"Khashayar Karimian","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06516099362023502,"gpt":0.3277711558011008,"spread":0.2626101621808658,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000158475,0.0004683145,0.0005207024,0.0007642225,0.0002319612,0.0004097028,0.0004338941,0.0003726793,0.003282758],"category_scores_gemma":[0.000166044,0.0001525547,0.0001683592,0.0005696961,0.0002288983,0.0003802952,0.0002253287,0.0005105593,0.001734859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005218981,"about_ca_system_score_gemma":0.0002596653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000687321,"about_ca_topic_score_gemma":0.0009670951,"domain_scores_codex":[0.9999276,0.00001159672,0.000005858221,0.00001588971,0.00002748136,0.00001148792],"domain_scores_gemma":[0.9999639,0.00000889077,0.000008903565,0.000002168931,0.00001127714,0.000004800933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001924492,0.000187072,0.0002580597,0.008589387,0.00005203797,0.0009507276,0.0001892389,0.002428489,0.213714,0.01339167,0.01094574,0.7491012],"study_design_scores_gemma":[0.00006939228,0.0007379036,0.002332706,0.0006770861,0.00006698129,0.003832285,0.00008727281,0.00103645,0.05997216,0.003368516,0.9277784,0.00004083799],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009252582,0.9788985,0.001503604,0.0003545271,0.0001519881,0.00002271185,0.00009860378,0.0000639617,0.009653527],"genre_scores_gemma":[0.05037754,0.9367908,0.001944929,0.0002616874,0.0002015496,0.00002969154,0.0001649609,0.000005067397,0.01022382],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003282758,"threshold_uncertainty_score":0.01098192,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2896200923","doi":"10.2174/1389557518666181015152657","title":"A Structural Chemistry Perspective on the Antimalarial Properties of Thiosemicarbazone Metal Complexes","year":2018,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Plasmodium falciparum; Malaria; Chloroquine; Drug; Antimalarial Agent; Drug discovery; Pharmacology; Drug resistance; Potency; Biology; Chemistry; Combinatorial chemistry; Biochemistry; In vitro; Immunology; Microbiology","authors":[{"name":"Kelly L. Summers","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1539136208889816,"gpt":0.3537406517896627,"spread":0.1998270309006811,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037193,0.0005044403,0.0004339476,0.0003564425,0.000335424,0.0007228839,0.0007715193,0.0006994695,0.003490519],"category_scores_gemma":[0.0001772072,0.0002694627,0.0003404806,0.0003321717,0.0005599054,0.0008095638,0.000499636,0.001409358,0.001456219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007734505,"about_ca_system_score_gemma":0.0002891551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005219437,"about_ca_topic_score_gemma":0.001039603,"domain_scores_codex":[0.999867,0.00003142376,0.000007037984,0.00002192431,0.00004233161,0.00003027353],"domain_scores_gemma":[0.9999416,0.00002018627,0.000007156499,0.00000453346,0.00001810093,0.000008431387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004533578,0.0005494981,0.0002679634,0.006982345,0.00009971741,0.002306288,0.0006209219,0.007531887,0.5064883,0.2460113,0.03765462,0.1910337],"study_design_scores_gemma":[0.0001090111,0.002688645,0.0005916582,0.000520353,0.00004144047,0.001860294,0.0002005445,0.003861446,0.1203606,0.03032875,0.8393766,0.00006064991],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07048945,0.7471995,0.0226867,0.02300682,0.003013893,0.0001510806,0.0003485226,0.0004324061,0.1326716],"genre_scores_gemma":[0.313978,0.6377095,0.01215614,0.005893428,0.001716897,0.0001481837,0.0003498315,0.00008313119,0.02796496],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003490519,"threshold_uncertainty_score":0.01167691,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2103529894","doi":"10.2174/138955710791185046","title":"Niacin: From Mechanisms of Action to Therapeutic Uses","year":2010,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Nutrition, Genetics, and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"St. Paul's Hospital","funders":"","keywords":"Niacin; Statin; Residual risk; Medicine; Clinical trial; Pharmacology; Lipoprotein; Cholesterol; Internal medicine; Bioinformatics; Biology","authors":[{"name":"Maha A. Al‐Mohaissen","is_ca":true},{"name":"S Pun","is_ca":false},{"name":"Jiří Fröhlich","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05975496187476474,"gpt":0.3655502319161291,"spread":0.3057952700413643,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004105457,0.0008929775,0.001543209,0.001892537,0.0003274107,0.001440677,0.000916559,0.001142867,0.003595003],"category_scores_gemma":[0.0003064388,0.0003661409,0.0004430801,0.001383412,0.0007852569,0.001713799,0.000858287,0.002105282,0.003108716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007499687,"about_ca_system_score_gemma":0.0006851461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005601827,"about_ca_topic_score_gemma":0.0008235776,"domain_scores_codex":[0.9997687,0.00004415392,0.00003044339,0.00004145251,0.00009420661,0.0000212252],"domain_scores_gemma":[0.9999092,0.00003095672,0.00001670847,0.000005536795,0.00002447383,0.00001322381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001565522,0.000123262,0.0001687155,0.01447312,0.00007632439,0.0004743536,0.0001536394,0.0004995178,0.0162957,0.01465663,0.01689627,0.9360259],"study_design_scores_gemma":[0.00002582451,0.0001259143,0.0004188205,0.001598638,0.00003758232,0.001116954,0.00007062139,0.0001206675,0.002761976,0.005196606,0.9885067,0.00001970795],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003638419,0.9958714,0.0004708866,0.0006053629,0.0002193408,0.000008986848,0.00002220292,0.00001488143,0.002423013],"genre_scores_gemma":[0.002095564,0.9951126,0.0006422536,0.0003306656,0.0001951218,0.0000183665,0.00003248734,0.000003497505,0.00156949],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003595003,"threshold_uncertainty_score":0.01202643,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2093425440","doi":"10.2174/138955710791383983","title":"Structure-Activity Relationships of Multifunctional Host Defence Peptides","year":2010,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Host (biology); Computational biology; Biology; Ecology","authors":[{"name":"Jason Kindrachuk","is_ca":false},{"name":"Scott Napper","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05477887532666764,"gpt":0.3083346686218112,"spread":0.2535557932951436,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003199525,0.0005821047,0.0006611685,0.0004691947,0.0001267518,0.0004464804,0.0004602322,0.0005735595,0.001804884],"category_scores_gemma":[0.0002607223,0.0002020965,0.0002651451,0.0006458696,0.0002035216,0.0005778466,0.0002814021,0.0006312176,0.001335265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003815044,"about_ca_system_score_gemma":0.0002325431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001804478,"about_ca_topic_score_gemma":0.0002656236,"domain_scores_codex":[0.9998918,0.00002175896,0.000009258034,0.00001828415,0.00004011938,0.00001868379],"domain_scores_gemma":[0.999925,0.00002634884,0.00002087132,0.000002755044,0.00001527361,0.000009774618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002751458,0.0001967712,0.0003360142,0.01133172,0.00008683754,0.0008474166,0.0000994486,0.003394956,0.3302834,0.008747339,0.00523151,0.6391695],"study_design_scores_gemma":[0.000112508,0.002046166,0.004779542,0.00111371,0.0001544251,0.005182971,0.0001005412,0.002152903,0.20021,0.006351957,0.7777287,0.00006671184],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009326911,0.9840337,0.001472322,0.0001759928,0.0001163279,0.00002332806,0.00004950844,0.00001856156,0.004783224],"genre_scores_gemma":[0.05970667,0.9314612,0.002912035,0.0003232456,0.0001739201,0.00004907378,0.0001437832,0.00000611467,0.005224004],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001804884,"threshold_uncertainty_score":0.006037951,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2052922936","doi":"10.2174/138955705774933383","title":"Modulation of HIV-1 Transcription by Cytokines and Chemokines","year":2005,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":36,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Chemokine; Transcription (linguistics); Transcription factor; Biology; Cell biology; Cytokine; Signal transduction; Immunology; Immune system; Gene; Genetics","authors":[{"name":"Katherine M. Copeland","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03921405786610778,"gpt":0.3325123226096614,"spread":0.2932982647435536,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002005281,0.0004640469,0.0006544864,0.0006074512,0.0002014691,0.0005176498,0.0004336238,0.0004873405,0.002940576],"category_scores_gemma":[0.0001437418,0.0001460046,0.0001620327,0.0006995128,0.0002087602,0.000529583,0.0002395075,0.0005599393,0.002637136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003846094,"about_ca_system_score_gemma":0.0004494401,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004294182,"about_ca_topic_score_gemma":0.0008942654,"domain_scores_codex":[0.9999256,0.00001251484,0.000006638575,0.00001253369,0.00003138355,0.00001129619],"domain_scores_gemma":[0.9999577,0.00001324889,0.000007016506,0.000001840261,0.00001391357,0.000006195436],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001052402,0.00007021549,0.0002069687,0.006690757,0.00003041481,0.0002734189,0.00006289678,0.0002424134,0.03331997,0.003973148,0.01598189,0.9390427],"study_design_scores_gemma":[0.00002499592,0.0002006527,0.001468491,0.000865022,0.00003711639,0.001324001,0.00007357326,0.0001246463,0.0109728,0.001972301,0.9829226,0.00001374575],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008894565,0.9950334,0.000281382,0.0002286466,0.0002050824,0.00001010676,0.0000211839,0.00001427089,0.00331654],"genre_scores_gemma":[0.003979069,0.9917381,0.0005912178,0.0002055348,0.0001977506,0.00001388274,0.00004186918,0.000002024797,0.003230514],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002940576,"threshold_uncertainty_score":0.009837151,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2034382007","doi":"10.2174/138955712800959134","title":"Biased Agonism of the Angiotensin II Type 1 Receptor","year":2012,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"","keywords":"G protein-coupled receptor; Heterotrimeric G protein; Angiotensin II; Signal transduction; Receptor; Functional selectivity; G protein-coupled receptor kinase; Cell biology; G protein; Agonist; Chemistry; Arrestin; Protein kinase A; Biology; Biochemistry; Kinase","authors":[{"name":"Claude Godin","is_ca":true},{"name":"Stephen S. G. Ferguson","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05984570010415319,"gpt":0.3209385646483264,"spread":0.2610928645441732,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001895641,0.0004116693,0.0006176496,0.0005852024,0.0001293222,0.000452018,0.0004352844,0.0004308139,0.00310216],"category_scores_gemma":[0.0001620855,0.0001579157,0.0002743063,0.0005040075,0.0001908891,0.0004748081,0.0003562738,0.0008882559,0.002110363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003254554,"about_ca_system_score_gemma":0.0002988948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002908924,"about_ca_topic_score_gemma":0.0006046811,"domain_scores_codex":[0.9999107,0.00001694111,0.000008668301,0.00001794523,0.00003271404,0.00001302198],"domain_scores_gemma":[0.9999639,0.00001278414,0.000008183885,0.00000150706,0.000008367891,0.000005232239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001629671,0.00009960934,0.0002234323,0.0141481,0.000112305,0.0005216827,0.0000639022,0.0006418044,0.03733549,0.009758561,0.02405179,0.9128804],"study_design_scores_gemma":[0.00003926742,0.0002761911,0.001076553,0.0009004875,0.00009215325,0.002320929,0.00003722021,0.0002525561,0.01023195,0.002465745,0.9822808,0.00002614701],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001361705,0.9934768,0.0005614385,0.0002628108,0.0002124381,0.00001194469,0.00005009091,0.00002459766,0.004038096],"genre_scores_gemma":[0.007585047,0.9887388,0.0005517971,0.000366318,0.0001947301,0.00001683165,0.00007480456,0.000003297896,0.002468313],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00310216,"threshold_uncertainty_score":0.01037776,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2015282586","doi":"10.2174/138955707780619590","title":"Emerging Drugs - Potential for Misuse in Sport and Doping Control Detection Strategies","year":2007,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"World Anti-Doping Agency","keywords":"Erythropoietin; Growth hormone; Androgen receptor; Pharmacology; Medicine; Hormone; Internal medicine; Prostate cancer; Cancer","authors":[{"name":"Mario Thevis","is_ca":false},{"name":"Wilhelm Schänzer","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03842300802741663,"gpt":0.3761373596494231,"spread":0.3377143516220065,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000755874,0.0005628177,0.001073456,0.001749594,0.0002523775,0.0008022204,0.0005848149,0.001040015,0.00615496],"category_scores_gemma":[0.0006474677,0.0001876294,0.0004201747,0.001227069,0.0003019814,0.0009712166,0.0003650408,0.0006677646,0.002414645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004436425,"about_ca_system_score_gemma":0.0008838788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005986434,"about_ca_topic_score_gemma":0.001478047,"domain_scores_codex":[0.999634,0.00007751626,0.00004023016,0.0000505259,0.0001707355,0.00002687749],"domain_scores_gemma":[0.999527,0.0002012321,0.00009857691,0.00001230229,0.0001282389,0.00003273585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009684781,0.0001116654,0.0006535489,0.006767093,0.00008026883,0.0006474309,0.00005906991,0.0002712478,0.005636426,0.002692797,0.01015827,0.9728253],"study_design_scores_gemma":[0.00005853954,0.0005020874,0.003229996,0.003120901,0.0002187979,0.00693713,0.0002221107,0.0003945039,0.00911792,0.003038513,0.9731266,0.00003290191],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001557779,0.992589,0.0006282862,0.0006251418,0.0001586989,0.00001594435,0.00004176769,0.00002152208,0.004361877],"genre_scores_gemma":[0.008615407,0.9847995,0.001104414,0.0004983346,0.0002485663,0.00002081086,0.00007015433,0.000003614762,0.004639216],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00615496,"threshold_uncertainty_score":0.02059036,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2033626292","doi":"10.2174/138955707781662627","title":"Novel Phospholipase-Resistant Lipid/Peptide Synthetic Lung Surfactants","year":2007,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Pulmonary surfactant; Context (archaeology); Chemistry; Peptide; Phospholipase; Biochemistry; Biology; Enzyme","authors":[{"name":"Robert H. Notter","is_ca":false},{"name":"Adrian L. Schwan","is_ca":false},{"name":"Zhengdong Wang","is_ca":false},{"name":"Alan J. Waring","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1405499564585827,"gpt":0.4512020770474702,"spread":0.3106521205888876,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002078645,0.0006014435,0.0006307999,0.0007734295,0.0001351244,0.0004234496,0.0004818945,0.000561605,0.001394669],"category_scores_gemma":[0.000169735,0.0001582071,0.0001744633,0.0006298399,0.0001953088,0.0006623644,0.0002912873,0.000642428,0.001683294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000253852,"about_ca_system_score_gemma":0.0003173469,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002156971,"about_ca_topic_score_gemma":0.0004263333,"domain_scores_codex":[0.9999076,0.00001275518,0.000009608897,0.00001626835,0.00004330051,0.00001037417],"domain_scores_gemma":[0.9999579,0.000009584477,0.00001231117,0.000001841146,0.00001155199,0.000006822082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001234955,0.0002240777,0.0001494221,0.009978843,0.00005960529,0.0008469119,0.00007871846,0.0008327353,0.1588738,0.005907208,0.008465885,0.8144593],"study_design_scores_gemma":[0.00006848652,0.0005825213,0.0008909661,0.0009241915,0.00007911519,0.003469543,0.00007465942,0.0003979725,0.06182333,0.001699696,0.9299567,0.00003297892],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003467069,0.991355,0.001269402,0.0001736182,0.0002030567,0.00002550681,0.0000325744,0.0000313103,0.003442418],"genre_scores_gemma":[0.009693152,0.9843888,0.002044284,0.0002151132,0.0001410365,0.0000321154,0.00007825973,0.000004992215,0.003402178],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001394669,"threshold_uncertainty_score":0.004665613,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2098779039","doi":"10.2174/138955711795906905","title":"Therapeutic Potential of Cannabinoids in the Treatment of Neuroinflammation Associated with Parkinsons Disease","year":2011,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"","keywords":"Neuroinflammation; Medicine; Disease; Pharmacology; Neuroscience; Internal medicine; Psychology","authors":[{"name":"Jonathan P. Little","is_ca":true},{"name":"Erika B. Villanueva","is_ca":true},{"name":"Andis Klegeris","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05883190040578421,"gpt":0.3462282912768172,"spread":0.287396390871033,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003505206,0.0005892422,0.00104794,0.001766561,0.0003028885,0.0004881863,0.0006143753,0.0008053285,0.002654876],"category_scores_gemma":[0.0002561627,0.0001512854,0.0003871743,0.001255165,0.00028752,0.0005189669,0.0004230556,0.00100233,0.001290105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004397972,"about_ca_system_score_gemma":0.0006164403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009585836,"about_ca_topic_score_gemma":0.002439254,"domain_scores_codex":[0.9998856,0.00001985511,0.00001676035,0.0000147252,0.00004776151,0.00001527591],"domain_scores_gemma":[0.9999187,0.00002816564,0.00001476276,0.000003020149,0.0000243097,0.00001101331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001974467,0.0001908572,0.0001913121,0.01107089,0.0001212569,0.0007293973,0.00007577222,0.0003769188,0.0127681,0.002205668,0.009411948,0.9626605],"study_design_scores_gemma":[0.0001467151,0.000590571,0.003967143,0.003175799,0.0002935708,0.00657675,0.0001387953,0.0003615776,0.008551713,0.002417885,0.9737321,0.00004737776],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007437058,0.9974865,0.0001910634,0.0001488843,0.0001101714,0.000009478671,0.00001624235,0.000007889513,0.001286041],"genre_scores_gemma":[0.004628326,0.9933441,0.0005713961,0.0001682391,0.0001397541,0.00001303465,0.0000422153,0.00000237501,0.001090607],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002654876,"threshold_uncertainty_score":0.00888145,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2130619870","doi":"10.2174/138955712800959143","title":"Functional Selectivity in GPCR Signaling: Understanding the Full Spectrum of Receptor Conformations","year":2012,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Functional selectivity; Allosteric regulation; Receptor; Ligand (biochemistry); Metabotropic glutamate receptor; Signal transduction; Metabotropic receptor; Chemistry; Rhodopsin-like receptors; Rhodopsin; Biology; Neuroscience; Computational biology; Agonist; Biochemistry","authors":[{"name":"Eugénie Goupil","is_ca":true},{"name":"Stéphane A. Laporte","is_ca":true},{"name":"Terence E. Hébert","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09623266167367109,"gpt":0.3148839943345764,"spread":0.2186513326609053,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007088326,0.0008744685,0.001560194,0.00122302,0.0003057034,0.0009510122,0.001126273,0.001341312,0.002566638],"category_scores_gemma":[0.0004253379,0.000300959,0.0003828404,0.001226194,0.001009068,0.002134039,0.0007367388,0.002109186,0.002636886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00108533,"about_ca_system_score_gemma":0.0008859628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007725139,"about_ca_topic_score_gemma":0.0007545883,"domain_scores_codex":[0.999778,0.00003939617,0.00002216644,0.00004236387,0.00008746603,0.00003065759],"domain_scores_gemma":[0.9998598,0.00005379326,0.00002347529,0.000008347334,0.0000373904,0.00001711181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009868469,0.00006440093,0.000183766,0.01460726,0.00007509153,0.0003410251,0.0001192189,0.0009551385,0.02190075,0.03068983,0.0184024,0.9125624],"study_design_scores_gemma":[0.0000229276,0.0001692703,0.0006451582,0.001153839,0.00007709245,0.001876274,0.00009609317,0.0003939396,0.006109945,0.009681836,0.9797305,0.00004307396],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004725359,0.995665,0.001068479,0.0005290438,0.000190744,0.000008452995,0.0000227852,0.00001872425,0.002024325],"genre_scores_gemma":[0.003119111,0.9943973,0.0008076708,0.0003563842,0.0002310171,0.00001044022,0.00003754259,0.0000034661,0.001037034],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002566638,"threshold_uncertainty_score":0.008586228,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2171604704","doi":"10.2174/1389557515666150414152933","title":"Regulation of Hypoxia-inducible Factor-1α and Vascular Endothelial Growth Factor Signaling by Plant Flavonoids","year":2015,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Angiogenesis; Luteolin; Pharmacology; Apigenin; Vascular endothelial growth factor; Cancer; In vivo; Chemotherapy; Quercetin; Medicine; Cancer research; Biology; Flavonoid; Biochemistry; VEGF receptors; Biotechnology; Internal medicine; Antioxidant","authors":[{"name":"Wasundara Fernando","is_ca":false},{"name":"H.P. Vasantha Rupasinghe","is_ca":true},{"name":"David W. Hoskin","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03871046658314149,"gpt":0.301331966667394,"spread":0.2626215000842526,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001566325,0.0004905265,0.0006040936,0.001068023,0.0002228553,0.000491544,0.0004023444,0.0005019483,0.002827198],"category_scores_gemma":[0.0001749694,0.000184089,0.0003251697,0.0009408843,0.000190252,0.0006883836,0.0003748908,0.0007330962,0.001546702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004471507,"about_ca_system_score_gemma":0.00059036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006203877,"about_ca_topic_score_gemma":0.001255835,"domain_scores_codex":[0.9999239,0.00001055741,0.00000946553,0.00001418477,0.00002888541,0.00001306915],"domain_scores_gemma":[0.9999459,0.00001424933,0.00001268463,0.000001803796,0.00001757377,0.000007951817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009597322,0.00008369896,0.0002728615,0.01908547,0.00009753154,0.0003143126,0.00009757666,0.0005202781,0.02815332,0.004816343,0.02354272,0.9229199],"study_design_scores_gemma":[0.00001599929,0.0001071368,0.001713588,0.001144566,0.00008750695,0.001188802,0.0000578959,0.0001394953,0.005240275,0.001821811,0.9884635,0.00001951131],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006030287,0.9970804,0.0002650556,0.0001868761,0.0001153535,0.000006084339,0.00003400966,0.00001223828,0.001696965],"genre_scores_gemma":[0.002634109,0.9956424,0.000318501,0.0001330312,0.00008012098,0.000009289628,0.0000687622,0.000001888972,0.00111191],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002827198,"threshold_uncertainty_score":0.009457946,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1999818233","doi":"10.2174/1389557033487881","title":"Inhibitors of Sialyltransferases: Potential Roles in Tumor Growth and Metastasis","year":2003,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Alchemy (Canada)","funders":"","keywords":"Glycoconjugate; Sialyltransferase; Metastasis; Cancer research; Enzyme; Glycosyltransferase; Sialic acid; Biology; Biochemistry; Medicine; Cancer; Internal medicine","authors":[{"name":"Nicholas Drinnan","is_ca":true},{"name":"Judy A. Halliday","is_ca":false},{"name":"Tracie Ramsdale","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02380886296800057,"gpt":0.3258913019100411,"spread":0.3020824389420405,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003740831,0.0008708611,0.0009586498,0.001089654,0.0002068975,0.0006067352,0.0006829805,0.0008529291,0.00227779],"category_scores_gemma":[0.0002138433,0.0002221118,0.0002811063,0.001205659,0.000366459,0.0007411993,0.0003572893,0.001120975,0.002779099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004639187,"about_ca_system_score_gemma":0.0003691344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004685828,"about_ca_topic_score_gemma":0.0009725689,"domain_scores_codex":[0.9998811,0.0000181723,0.00001105537,0.00001837768,0.00005456999,0.00001657282],"domain_scores_gemma":[0.9999239,0.00002316693,0.0000144601,0.00000402564,0.00002137807,0.00001310922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001849468,0.0001569855,0.0002158859,0.006124493,0.00006789978,0.0004538297,0.0000742316,0.0007889846,0.04218103,0.004819934,0.01436653,0.9305653],"study_design_scores_gemma":[0.00006927115,0.0003444338,0.001257343,0.0008802507,0.00008335528,0.002433619,0.00005466495,0.0002621409,0.01686126,0.002637719,0.9750884,0.00002760961],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008462016,0.9963436,0.0004352237,0.0001592372,0.0001180115,0.000008815196,0.0000182298,0.00001944292,0.002051364],"genre_scores_gemma":[0.003608641,0.9937721,0.0005136018,0.0001497293,0.00008320437,0.00001278303,0.00004313841,0.000002385652,0.00181448],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00227779,"threshold_uncertainty_score":0.007619977,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1991443131","doi":"10.2174/1389557033488097","title":"Recent Developments in Novel Pyrrolo[2,1-c][1,4]Benzodiazepine Conjugates: Synthesis and Biological Evaluation","year":2003,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":26,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"DNA; Chemistry; Nucleic acid; Small molecule; Stereochemistry; Context (archaeology); Transcription (linguistics); Biochemistry; RNA; Substituent; Biological activity; Biology; In vitro; Gene","authors":[{"name":"Rohtash Kumar","is_ca":true},{"name":"J. William Lown","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1882911730294614,"gpt":0.3986680311449859,"spread":0.2103768581155245,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004058192,0.0005346037,0.0003604938,0.0003015579,0.0001488486,0.000389553,0.0003373398,0.0004472758,0.00168445],"category_scores_gemma":[0.0002733534,0.0001853756,0.0001963825,0.0002801664,0.0002377336,0.0005554056,0.0002171289,0.0004019017,0.000587618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003891788,"about_ca_system_score_gemma":0.0001883567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003361132,"about_ca_topic_score_gemma":0.0003638947,"domain_scores_codex":[0.9998418,0.000047998,0.00001596127,0.00003408934,0.000037242,0.00002289493],"domain_scores_gemma":[0.9998767,0.00001917254,0.00004180084,0.000007607156,0.00002606598,0.00002856379],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005690051,0.0002931189,0.0003510634,0.001595622,0.00004502735,0.0003163754,0.00016574,0.001515079,0.9354896,0.001991343,0.0005813704,0.05708668],"study_design_scores_gemma":[0.0002098219,0.006138249,0.002322053,0.00006417804,0.0001085733,0.001449506,0.00005361315,0.001628482,0.9012522,0.000284716,0.08643977,0.00004882813],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.7624929,0.1791501,0.0372753,0.000826128,0.0003193096,0.000690866,0.000625536,0.0004050955,0.01821478],"genre_scores_gemma":[0.8889787,0.07903565,0.01953839,0.0004932017,0.0002048254,0.000352043,0.0007601375,0.00007033243,0.01056667],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.00168445,"threshold_uncertainty_score":0.005635083,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2049371898","doi":"10.2174/1389557053175416","title":"Transglutaminases as Targets for Pharmacological Inhibition","year":2005,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Blood properties and coagulation","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Apotex (Canada)","funders":"","keywords":"Tissue transglutaminase; Autoantibody; Biology; Cell biology; Immunology; Medicine; Enzyme; Biochemistry; Antibody","authors":[{"name":"Jolanta Wodzinska","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1059387751754702,"gpt":0.4064776623548582,"spread":0.300538887179388,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004531328,0.0008932716,0.001267747,0.001530789,0.0002376364,0.0007603046,0.0007585399,0.001024483,0.003220641],"category_scores_gemma":[0.0002555058,0.0002622986,0.0004658425,0.001058644,0.00037037,0.0008650788,0.0004929705,0.001756757,0.003024933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004972249,"about_ca_system_score_gemma":0.0003268668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000368316,"about_ca_topic_score_gemma":0.0008442059,"domain_scores_codex":[0.999846,0.00002896936,0.00001501779,0.00002684773,0.00006404018,0.0000191619],"domain_scores_gemma":[0.9999359,0.00002122477,0.0000112436,0.000004316882,0.00001760855,0.000009701691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002378493,0.0003191893,0.0002072812,0.007082959,0.0001438229,0.001026401,0.0001379093,0.0008046399,0.04588496,0.01005801,0.02196842,0.9121285],"study_design_scores_gemma":[0.0001561497,0.0003942341,0.000848758,0.000850571,0.00009035545,0.002566603,0.00004192988,0.0002839799,0.01002999,0.002734288,0.9819749,0.00002818964],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0012398,0.993001,0.001042728,0.0003273334,0.0002880627,0.00002860906,0.00003345746,0.00004082027,0.0039982],"genre_scores_gemma":[0.006789868,0.9859723,0.001477892,0.0005135107,0.0002009899,0.00004878766,0.0001050466,0.000007068524,0.004884525],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003220641,"threshold_uncertainty_score":0.01077414,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2161454100","doi":"10.2174/138955708784912175","title":"Antipsychotic Drugs and Cerebrovascular Events in Elderly Patients with Dementia: A Systematic Review","year":2008,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Neurological Disorders and Treatments","field":"Neuroscience","cited_by":22,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Dementia; Antipsychotic; Medicine; Vascular dementia; Psychiatry; Psychology; Intensive care medicine; Schizophrenia (object-oriented programming); Internal medicine; Disease","authors":[{"name":"Sara Mazzucco","is_ca":false},{"name":"Andrea Cipriani","is_ca":false},{"name":"Corrado Barbui","is_ca":false},{"name":"Salvatore Monaco","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02803461074920064,"gpt":0.2928610375522639,"spread":0.2648264268030633,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002451871,0.0008133589,0.004425974,0.003515485,0.0002980309,0.0009841617,0.0008099928,0.0009540101,0.00285614],"category_scores_gemma":[0.009725315,0.000523731,0.003473077,0.004861349,0.0003327204,0.0007996137,0.0005933639,0.0004739876,0.0002015288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001264601,"about_ca_system_score_gemma":0.004011217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006191552,"about_ca_topic_score_gemma":0.01980083,"domain_scores_codex":[0.9985488,0.0005018121,0.0004707662,0.0001270394,0.0002976301,0.00005397647],"domain_scores_gemma":[0.9943948,0.003613145,0.001342551,0.00005131265,0.0005080787,0.00009015035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0006140164,0.00003830293,0.002069711,0.8566146,0.01370971,0.0002345058,0.0001426624,0.0001941849,0.000193238,0.0002142013,0.004679085,0.1212958],"study_design_scores_gemma":[0.001118627,0.0006465905,0.02012789,0.7473468,0.1682509,0.002097698,0.0003872611,0.0002519321,0.000416266,0.0006174007,0.05867128,0.00006737699],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007560753,0.9988608,0.00003118889,0.00006380782,0.00003481474,0.00005166152,0.00008380823,0.000002146976,0.0001156379],"genre_scores_gemma":[0.006652724,0.9928833,0.0001560458,0.00009928906,0.00003181163,0.0000563898,0.00005545327,6.211645e-7,0.00006445293],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006191552,"threshold_uncertainty_score":0.01296687,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2404343343","doi":"10.2174/1389557515666150722105705","title":"Understanding the Molecular Mechanisms of Rifaximin in the Treatment of Gastrointestinal Disorders - A Focus on the Modulation of Host Tissue Function","year":2015,"lang":"en","type":"article","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Pneumocystis jirovecii pneumonia detection and treatment","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Research Canada","funders":"Canadian Institutes of Health Research","keywords":"Rifaximin; Pregnane X receptor; Irritable bowel syndrome; Context (archaeology); Gastrointestinal tract; Biology; Nuclear receptor; Antibiotics; Pharmacology; Medicine; Internal medicine; Microbiology; Transcription factor; Gene; Biochemistry","authors":[{"name":"Simon A. Hirota","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.07800590629972365,"gpt":0.2990064598941174,"spread":0.2210005535943937,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004780338,0.0005131659,0.0007517852,0.0005691292,0.0002061465,0.0007745465,0.0004970313,0.0008896159,0.001879059],"category_scores_gemma":[0.0002463716,0.0002159159,0.0003733234,0.0003642579,0.0005243127,0.001161836,0.000438933,0.001549677,0.0007503136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004907695,"about_ca_system_score_gemma":0.0006596596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003942198,"about_ca_topic_score_gemma":0.0008601545,"domain_scores_codex":[0.999831,0.00005132317,0.00001760201,0.00002535593,0.00004205646,0.00003257207],"domain_scores_gemma":[0.9998711,0.00003177533,0.00003614754,0.000006736091,0.00003600685,0.00001817923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007542815,0.0004031183,0.001119408,0.01625451,0.00020084,0.001303442,0.0004282734,0.001433183,0.2043855,0.02009405,0.01737104,0.7362524],"study_design_scores_gemma":[0.0002256225,0.002971472,0.009708083,0.002743207,0.0003800163,0.006115155,0.0003853467,0.002018164,0.07260424,0.01187759,0.8908651,0.0001059807],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004682293,0.9858791,0.002924773,0.003246833,0.0003148957,0.0000421618,0.00004897435,0.00003700383,0.002823984],"genre_scores_gemma":[0.04252591,0.9490945,0.003835802,0.001403795,0.0007004884,0.00007214347,0.00009257851,0.000008664531,0.002266067],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001879059,"threshold_uncertainty_score":0.006286085,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2026927555","doi":"10.2174/1389557053175371","title":"Taxol Anticancer Activity and DNA Binding","year":2005,"lang":"en","type":"article","venue":"Mini-Reviews in Medicinal Chemistry","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"DNA; Intercalation (chemistry); Chemistry; Helix (gastropod); Binding constant; Stereochemistry; In vitro; Base pair; Biophysics; Capillary electrophoresis; Binding site; Biochemistry; Biology; Chromatography; Organic chemistry","authors":[{"name":"H. Malonga","is_ca":false},{"name":"J. F. Neault","is_ca":true},{"name":"S. Diamantoglou","is_ca":false},{"name":"H.A. Tajmir‐Riahi","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.01327848252895512,"gpt":0.2808103437073496,"spread":0.2675318611783945,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001033074,0.0002575296,0.0001917029,0.000249109,0.0001514338,0.0003423099,0.000250156,0.000366603,0.003376144],"category_scores_gemma":[0.0003770039,0.000126919,0.0001335692,0.0002579324,0.0002114117,0.0001894197,0.0001478197,0.0003502838,0.0006392268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004161613,"about_ca_system_score_gemma":0.000192084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001195022,"about_ca_topic_score_gemma":0.001050775,"domain_scores_codex":[0.9997775,0.00003752534,0.000008892081,0.0000521379,0.00007868219,0.00004524245],"domain_scores_gemma":[0.99984,0.00006203495,0.0000426615,0.000007090051,0.00002739151,0.00002075573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001320954,0.00002504237,0.0006593315,0.0001209031,0.00001163342,0.00003680769,0.00001693226,0.0001787624,0.9935133,0.0002690197,0.00005885119,0.004977394],"study_design_scores_gemma":[0.000009378621,0.0002293575,0.005798683,0.00001089825,0.0000134626,0.0002322789,0.00002027261,0.0005617444,0.9887326,0.0001095883,0.004276345,0.000005316181],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9604754,0.02723624,0.004770872,0.0001815906,0.0000228149,0.00006212114,0.0004993503,0.00006174797,0.006689827],"genre_scores_gemma":[0.9883235,0.005144828,0.001435317,0.00009076719,0.00001206612,0.00003286285,0.0007150011,0.00001001607,0.004235769],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.003376144,"threshold_uncertainty_score":0.01129436,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2067576016","doi":"10.2174/138955708784534481","title":"Activation and Regulation of Toll-like Receptor 9: CpGs and Beyond","year":2008,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Nucleic acid; TLR9; Toll-Like Receptor 9; Biology; Innate immune system; CpG site; DNA; Receptor; Biochemistry; DNA methylation; Cell biology; Computational biology; Gene; Gene expression","authors":[{"name":"Jason Kindrachuk","is_ca":true},{"name":"Jean Potter","is_ca":false},{"name":"Heather L. Wilson","is_ca":false},{"name":"Philip Griebel","is_ca":false},{"name":"Lorne A. Babiuk","is_ca":false},{"name":"Scott Napper","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02388056803320268,"gpt":0.2913055730302087,"spread":0.267425004997006,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002284283,0.0004999802,0.0006262804,0.0004079476,0.0001696665,0.0007365401,0.0005048905,0.0007563388,0.00183938],"category_scores_gemma":[0.0002669554,0.000139344,0.000246877,0.0005164982,0.0003761743,0.000926005,0.0004274468,0.0008103432,0.001069193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004164056,"about_ca_system_score_gemma":0.0006417505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003958298,"about_ca_topic_score_gemma":0.0003435811,"domain_scores_codex":[0.999827,0.00002837368,0.00002616201,0.00004713902,0.00004315163,0.00002819122],"domain_scores_gemma":[0.9998904,0.00002956905,0.00003445636,0.000004317008,0.00002533406,0.00001583611],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004183599,0.0001067685,0.0008142275,0.03252565,0.0001076142,0.001485491,0.0005738657,0.001077207,0.3516409,0.0338965,0.01250498,0.5648484],"study_design_scores_gemma":[0.00001676071,0.000344375,0.005498538,0.002212079,0.00009884837,0.004431905,0.0002693936,0.0004305751,0.06640568,0.009114584,0.9111066,0.00007072598],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005074815,0.9887798,0.001913994,0.0007644453,0.0006037897,0.0000139614,0.0001013088,0.00003849296,0.002709405],"genre_scores_gemma":[0.02975955,0.9624864,0.001753996,0.0009146439,0.0008095534,0.00003639658,0.0001919719,0.00001290974,0.004034567],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00183938,"threshold_uncertainty_score":0.006153286,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2118834288","doi":"10.2174/138955708783744065","title":"Inhibition of Orotidine 5-Monophosphate Decarboxylase and Its Therapeutic Potential","year":2008,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Toronto General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Decarboxylation; Uridine; Biochemistry; Nucleotide; Enzyme; Context (archaeology); Chemistry; Drug discovery; Biology; RNA; Gene; Catalysis","authors":[{"name":"Lakshmi P. Kotra","is_ca":true},{"name":"Maria Elena Meza‐Avina","is_ca":true},{"name":"L. Wei","is_ca":false},{"name":"M. Buhendwa","is_ca":false},{"name":"E. Poduch","is_ca":false},{"name":"Angélica M. Bello","is_ca":false},{"name":"E.F. Pai","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02671068497864688,"gpt":0.3064417185729604,"spread":0.2797310335943136,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002132667,0.0005933707,0.0008209973,0.0007721533,0.0001464592,0.0004584042,0.0005387412,0.0008571866,0.002261583],"category_scores_gemma":[0.0001341724,0.0001789165,0.0002525626,0.0006105853,0.0002159556,0.0005666491,0.0003110464,0.0008539,0.001849052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004314195,"about_ca_system_score_gemma":0.0002962527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000329461,"about_ca_topic_score_gemma":0.0006258967,"domain_scores_codex":[0.999908,0.00001592267,0.000007270672,0.00001539783,0.00003748221,0.00001599052],"domain_scores_gemma":[0.9999563,0.00001300827,0.000009671782,0.000001972939,0.00001176582,0.000007320004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001708149,0.0001478491,0.0001705864,0.006296125,0.00006661491,0.0008141042,0.00006186152,0.0007786508,0.06169907,0.00652383,0.01417721,0.9090933],"study_design_scores_gemma":[0.00004996264,0.0003543202,0.00113887,0.0006203523,0.00006323549,0.003574651,0.0000414714,0.0003248777,0.0260936,0.002378755,0.9653358,0.00002402154],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001681424,0.9932286,0.0008381975,0.000351121,0.000195071,0.00001144232,0.00002085322,0.00002357269,0.003649593],"genre_scores_gemma":[0.01023939,0.9836234,0.0009940179,0.0004050129,0.0002090083,0.00002902315,0.00007428162,0.000004652947,0.00442117],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002261583,"threshold_uncertainty_score":0.007565737,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2010991468","doi":"10.2174/138955708783331531","title":"The Adipocyte as a Novel TSH Target","year":2008,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Thyroid Disorders and Treatments","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Canada","funders":"","keywords":"Endocrinology; Internal medicine; Adipocyte; Leptin; Adipose tissue; Receptor; Hormone; Thyroid; Medicine; Thyroid-stimulating hormone; Thyroid hormone receptor; Biology; Obesity","authors":[{"name":"Alexander Sorisky","is_ca":true},{"name":"Tamires Ramborger Antunes","is_ca":false},{"name":"AnneMarie Gagnon","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04824482518165665,"gpt":0.361597261812943,"spread":0.3133524366312863,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002597698,0.0004748866,0.0009326946,0.0008925731,0.0001868636,0.0007626383,0.0005226917,0.0008359194,0.003021284],"category_scores_gemma":[0.0001247788,0.0001747062,0.0002880561,0.0007151101,0.0002785563,0.0007823133,0.0003734005,0.001000735,0.002231068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003917498,"about_ca_system_score_gemma":0.0005065671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005594453,"about_ca_topic_score_gemma":0.001200922,"domain_scores_codex":[0.9999181,0.00001531692,0.000008399368,0.0000145033,0.00003116369,0.00001262509],"domain_scores_gemma":[0.9999545,0.00001561571,0.000008920249,0.000001658654,0.00001339947,0.00000595651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001857319,0.0001095338,0.0002811634,0.01082119,0.00007638205,0.001133927,0.0001076292,0.0004402664,0.04053281,0.008490958,0.01751829,0.9203021],"study_design_scores_gemma":[0.00004341798,0.0001953898,0.001064259,0.0009707854,0.00009515656,0.003084611,0.000095531,0.0001960085,0.007697093,0.00224309,0.9842927,0.00002198995],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000719439,0.9968082,0.0003628334,0.000331554,0.0002089348,0.000005369113,0.00001393171,0.00001035202,0.001539383],"genre_scores_gemma":[0.004728943,0.991623,0.0004755941,0.0002840447,0.0002193084,0.000009619845,0.0000447025,0.000001866703,0.002612915],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003021284,"threshold_uncertainty_score":0.01010716,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2951018521","doi":"10.2174/138955706775197802","title":"Solid-Phase Organic Synthesis (SPOS) of Modulators of Estrogenic and Androgenic Action","year":2005,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Steroid Chemistry and Biochemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval","funders":"","keywords":"Chemistry; Nuclear receptor; Agonist; Androgen receptor; Receptor; Estrone; Steroid; Estrogen receptor; Dihydrotestosterone; Pharmacology; Hormone; Sulfotransferase; Internal medicine; Estrogen; Endocrinology; Androgen; Enzyme; Biochemistry; Biology; Medicine; Prostate cancer; Transcription factor; Cancer","authors":[{"name":"Donald Poirier","is_ca":true},{"name":"René Maltais","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0402330091600611,"gpt":0.4023401762124462,"spread":0.3621071670523851,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001730664,0.0007711249,0.000747636,0.0008287256,0.0002620956,0.0004110932,0.0005526448,0.0005270691,0.00556908],"category_scores_gemma":[0.000177716,0.0002658273,0.0003909782,0.0008850983,0.0003754524,0.0006552787,0.0004475536,0.0006795048,0.006077911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004837137,"about_ca_system_score_gemma":0.0005221011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003377256,"about_ca_topic_score_gemma":0.0007503408,"domain_scores_codex":[0.9998622,0.00001843803,0.000007111682,0.00002431037,0.00006726367,0.00002063839],"domain_scores_gemma":[0.9999574,0.00001053827,0.0000113645,0.000004656159,0.000009278549,0.000006683769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002277199,0.0002810419,0.0001826119,0.009615611,0.0001102333,0.0007153887,0.000103937,0.002885916,0.2357083,0.03371876,0.01875469,0.6976959],"study_design_scores_gemma":[0.0001189384,0.0007507089,0.000476966,0.0003892486,0.00005397643,0.001434141,0.00005087744,0.001338068,0.1876629,0.006315408,0.8013709,0.0000377524],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02526541,0.8695385,0.04068921,0.0009236924,0.001517907,0.0003294516,0.0007030862,0.0006022223,0.06043061],"genre_scores_gemma":[0.1090491,0.8275352,0.02675762,0.0006885965,0.0003981224,0.0002803782,0.0008610647,0.00005804151,0.03437196],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00556908,"threshold_uncertainty_score":0.01863039,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2049383708","doi":"10.2174/1389557033487737","title":"Aspects of the Stability and Bioavailability of Carbohydrates and Carbohydrate Derivatives","year":2003,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Alchemy (Canada)","funders":"","keywords":"Bioavailability; Carbohydrate; Drug; Chemistry; Drug discovery; Computational biology; Pharmacology; Biochemistry; Biology","authors":[{"name":"Nicholas Drinnan","is_ca":true},{"name":"Frank Vari","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04263394754162948,"gpt":0.3289122398963039,"spread":0.2862782923546744,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004235862,0.0005089658,0.0007046128,0.0007260148,0.0002557939,0.0007868115,0.000549074,0.0007932096,0.001622412],"category_scores_gemma":[0.000350547,0.0002171298,0.0002570577,0.0008243175,0.0004810652,0.0008431266,0.0003475356,0.0008156282,0.0009780038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006676096,"about_ca_system_score_gemma":0.000428249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00123318,"about_ca_topic_score_gemma":0.0008009605,"domain_scores_codex":[0.9997985,0.00003329435,0.00001597215,0.00003572569,0.00009039319,0.00002626258],"domain_scores_gemma":[0.9998939,0.00004115992,0.0000243452,0.000005440837,0.00002594594,0.000009241144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003015386,0.0001048426,0.0004893197,0.007891228,0.00006064206,0.000954129,0.0001515231,0.002129942,0.2177392,0.02034085,0.005003619,0.7448333],"study_design_scores_gemma":[0.00005269385,0.001015753,0.005456597,0.0009862216,0.0001150664,0.005561224,0.0002115737,0.001433482,0.1989165,0.01462372,0.7715402,0.00008697007],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007527158,0.9834977,0.00132741,0.0004326102,0.0001345582,0.00001100863,0.00004212828,0.00001173838,0.007015631],"genre_scores_gemma":[0.06160634,0.9297116,0.002029071,0.000326422,0.0002596358,0.00003817129,0.0001032656,0.000007771359,0.005917817],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001622412,"threshold_uncertainty_score":0.00542748,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2125624552","doi":"10.2174/138955709787316047","title":"Genetics and Function of the Capsules of Burkholderia pseudomallei and Their Potential as Therapeutic Targets","year":2009,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Burkholderia infections and melioidosis","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"","keywords":"Burkholderia pseudomallei; Melioidosis; Virulence; Biology; Antibiotics; Organism; Microbiology; Gene; Pneumonia; Burkholderia; Bacteria; Genetics; Medicine","authors":[{"name":"Shauna Reckseidler-Zenteno","is_ca":true},{"name":"Richard Moore","is_ca":true},{"name":"Donald E. Woods","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03273096738786042,"gpt":0.3059411482513161,"spread":0.2732101808634557,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003319283,0.0005986534,0.001058783,0.0009148194,0.0001693376,0.0006592919,0.0005967538,0.0008477608,0.002334778],"category_scores_gemma":[0.0002616442,0.0002337176,0.0002672534,0.0008686864,0.0003612782,0.0008243619,0.0003292786,0.0009213603,0.00195577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005409659,"about_ca_system_score_gemma":0.0004188492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004777225,"about_ca_topic_score_gemma":0.0008416782,"domain_scores_codex":[0.9998937,0.00002228321,0.0000117118,0.00001562187,0.00004247727,0.00001435516],"domain_scores_gemma":[0.9999032,0.00003272332,0.00001995388,0.000004427546,0.00002450344,0.0000151495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001877301,0.000138023,0.0002363295,0.01068531,0.00007720461,0.0006809778,0.00009651405,0.001248899,0.04272,0.007593381,0.01603714,0.9202984],"study_design_scores_gemma":[0.00005448203,0.0002272246,0.001639324,0.0009848764,0.00006154272,0.002675662,0.00007585854,0.0003496785,0.00699117,0.003062289,0.9838515,0.00002637993],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005279985,0.9974624,0.0002944796,0.0002007104,0.00008917732,0.00000601973,0.00001544377,0.000008765809,0.001394877],"genre_scores_gemma":[0.003332303,0.9946395,0.0004933669,0.0001269807,0.00008034848,0.00001085584,0.0000438784,0.000001832528,0.00127095],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002334778,"threshold_uncertainty_score":0.007810593,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4200418065","doi":"10.2174/1570193x19666211221150119","title":"Discovery and Development of Antibacterial Agents: Fortuitous and Designed","year":2021,"lang":"en","type":"article","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Cape Breton University","funders":"","keywords":"Clinical trial; Antibiotics; Drug development; Drug discovery; Drug resistance; Antibiotic resistance; Broad spectrum","authors":[],"retraction":null,"screen_n_in":null,"score":{"opus":0.02748821031224511,"gpt":0.2923584075383907,"spread":0.2648701972261455,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001112378,0.000715779,0.001053407,0.0009826584,0.0004969967,0.002096635,0.0007619986,0.001281564,0.00317695],"category_scores_gemma":[0.0009283884,0.0004700863,0.0006298501,0.0006510718,0.001398893,0.00297089,0.001058295,0.002921545,0.002179432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007747044,"about_ca_system_score_gemma":0.001279354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003737611,"about_ca_topic_score_gemma":0.0006449423,"domain_scores_codex":[0.9994792,0.000120514,0.0000474018,0.0001083527,0.0001745899,0.00006991509],"domain_scores_gemma":[0.9997341,0.00007719408,0.00004123635,0.00002864261,0.00007716906,0.00004157682],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003720615,0.0004536955,0.0007229145,0.01701004,0.0001776433,0.001163044,0.0005888246,0.002278078,0.1233225,0.162024,0.02954522,0.662342],"study_design_scores_gemma":[0.00007564278,0.0009701261,0.0005385556,0.001123703,0.0001005073,0.001715604,0.000138179,0.0008818689,0.02828353,0.02430627,0.9418048,0.00006118464],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008338843,0.9358829,0.02394118,0.008233805,0.002737378,0.0002297537,0.0003738076,0.000242228,0.02002015],"genre_scores_gemma":[0.03927756,0.9224431,0.01981957,0.004508526,0.001282637,0.0002445687,0.000414829,0.00005440239,0.01195476],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00317695,"threshold_uncertainty_score":0.01062799,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2075214872","doi":"10.2174/1389557043403738","title":"Modulation of the Arachidonic Cascade with &amp;#969;3 Fatty Acids or Analogues: Potential Therapeutic Benefits","year":2004,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Fatty Acid Research and Health","field":"Nursing","cited_by":12,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"Waalse Gewest","keywords":"Arachidonic acid; Pathological; Medicine; Inflammation; In vivo; Fatty acid; Chemistry; Pharmacology; Physiology; Endocrinology; Internal medicine; Enzyme; Biochemistry; Biology; Biotechnology","authors":[{"name":"Isabelle Roland","is_ca":false},{"name":"Xavier de Leval","is_ca":false},{"name":"Brigitte Évrard","is_ca":false},{"name":"Bernard Pirotte","is_ca":false},{"name":"Jean-Michel Dogné","is_ca":false},{"name":"Luc Delattre","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08582186270660436,"gpt":0.3763882478013511,"spread":0.2905663850947467,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002112739,0.0004946509,0.0007854922,0.001029514,0.0002237173,0.0006688202,0.0003812461,0.000849771,0.007356791],"category_scores_gemma":[0.0001928156,0.0001404892,0.0003353086,0.0008084795,0.0002098215,0.0006125779,0.0003632571,0.0007501549,0.003275756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002309445,"about_ca_system_score_gemma":0.0003738234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004188079,"about_ca_topic_score_gemma":0.001204055,"domain_scores_codex":[0.9999396,0.00001232148,0.000008975951,0.000009922188,0.00001858681,0.00001060004],"domain_scores_gemma":[0.9999424,0.00002270847,0.00001110785,0.000002555469,0.00001427603,0.000006889554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002692691,0.0002161287,0.0002213089,0.01110101,0.00006389411,0.0008180824,0.0001027005,0.0001943956,0.0303515,0.003313852,0.008080937,0.945267],"study_design_scores_gemma":[0.00009957171,0.0008288903,0.002681631,0.003620585,0.0001656124,0.004871025,0.0002808323,0.0001480393,0.01113548,0.003847353,0.9722871,0.00003388474],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001387794,0.9927564,0.0003387037,0.0004671144,0.0002545225,0.00001216916,0.0000345529,0.00001282939,0.004735967],"genre_scores_gemma":[0.006095564,0.9892032,0.0007299869,0.0002787525,0.0001898577,0.00001712344,0.0000532348,0.000002655621,0.003429739],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007356791,"threshold_uncertainty_score":0.02461094,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3213500083","doi":"10.2174/1389557521666211116122615","title":"Hydroxycinnamic Acids and Their Related Synthetic Analogs: An Updateof Pharmacological Activities","year":2021,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Université de Moncton","funders":"","keywords":"Hydroxycinnamic acid; Antioxidant; Biological activity; Chemistry; Computational biology; Nanotechnology; Biochemistry; Combinatorial chemistry; Biology; Materials science; In vitro","authors":[{"name":"Ayyoub Selka","is_ca":true},{"name":"Fanta J. Ndongou Moutombi","is_ca":true},{"name":"Jacques Jean‐François","is_ca":false},{"name":"Mohamed Touaibia","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05447907444244598,"gpt":0.3703380726090555,"spread":0.3158589981666095,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003649418,0.0008308102,0.0008862849,0.001298909,0.0002157977,0.0007212291,0.0005570321,0.0004754234,0.005531898],"category_scores_gemma":[0.0003256041,0.0002829975,0.0003871649,0.001276845,0.0003275837,0.001002757,0.0005226897,0.001508605,0.002093829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003757003,"about_ca_system_score_gemma":0.0005519962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004102834,"about_ca_topic_score_gemma":0.001141536,"domain_scores_codex":[0.9998763,0.00001559989,0.00001424586,0.0000235078,0.00004956571,0.00002068939],"domain_scores_gemma":[0.9999001,0.00003537906,0.00001756021,0.000005042205,0.00002869439,0.00001317142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001822271,0.0001896696,0.0001485411,0.02607857,0.0001147354,0.0003028525,0.00008961357,0.0007724801,0.0318267,0.006675997,0.01882278,0.9147958],"study_design_scores_gemma":[0.00003235994,0.0003130956,0.0006580199,0.001142977,0.0001246456,0.000903353,0.0000469843,0.0001677135,0.006887382,0.001554907,0.9881408,0.00002767314],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008406094,0.9962908,0.0003928822,0.0001373306,0.0002574706,0.00001077158,0.00005856957,0.00001939674,0.001992074],"genre_scores_gemma":[0.003511355,0.9943873,0.0004550001,0.0001691471,0.0001449584,0.00001102917,0.00008804289,0.000003572357,0.001229524],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005531898,"threshold_uncertainty_score":0.01850605,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2409633283","doi":"10.2174/1389557515666160509125829","title":"Review of Cytotoxic CA4 Analogues that Do Not Target Microtubules: Implications for CA4 Development","year":2016,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University; University of Windsor","funders":"","keywords":"Cytotoxic T cell; Microtubule; Chemistry; Cell biology; Biology; Biochemistry; In vitro","authors":[{"name":"Daniel Tarade","is_ca":true},{"name":"Siyaram Pandey","is_ca":true},{"name":"James McNulty","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04955457320813372,"gpt":0.349008924551681,"spread":0.2994543513435473,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004441586,0.0008605206,0.001154648,0.001838585,0.0002856051,0.0006973177,0.0009694415,0.0008137624,0.00443649],"category_scores_gemma":[0.0005667301,0.0003587392,0.0005096963,0.001788164,0.0003470812,0.001082096,0.0004957549,0.001650049,0.002383112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000575306,"about_ca_system_score_gemma":0.0008005671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006463721,"about_ca_topic_score_gemma":0.001399099,"domain_scores_codex":[0.9998527,0.00002377124,0.00002458335,0.00002803031,0.00005468597,0.00001629318],"domain_scores_gemma":[0.9997815,0.00008267874,0.00004097557,0.000008330379,0.00006032913,0.00002610569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001287083,0.0001099599,0.0001163773,0.02908881,0.0001193289,0.0003110399,0.00007689771,0.0007821355,0.006869651,0.004576395,0.05367922,0.9041414],"study_design_scores_gemma":[0.00001993729,0.0001242398,0.0003691721,0.001561733,0.00009227187,0.0008186736,0.00002576106,0.00009327455,0.001136084,0.0008633354,0.9948798,0.00001569781],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002458504,0.9973379,0.0002802384,0.000276451,0.0003930233,0.00001100556,0.00004043937,0.00001744392,0.00139757],"genre_scores_gemma":[0.001102271,0.997039,0.0003641131,0.0002836396,0.0001790854,0.00001408575,0.0000693624,0.000003482783,0.0009449704],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00443649,"threshold_uncertainty_score":0.01484156,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3081275841","doi":"10.2174/1389557520999200824103803","title":"Drug Discovery by Drug Repurposing: Combating COVID-19 in the 21st Century","year":2020,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"","keywords":"Drug repositioning; Repurposing; Drug; Medicine; Hydroxychloroquine; Coronavirus disease 2019 (COVID-19); Pandemic; Death toll; Coronavirus; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Pharmacology; Approved drug; Drug discovery; Intensive care medicine; Virology; Bioinformatics; Biology; Environmental health; Infectious disease (medical specialty); Disease; Internal medicine","authors":[{"name":"Nitesh Sanghai","is_ca":true},{"name":"Kashfia Shafiq","is_ca":true},{"name":"Geoffrey K. Tranmer","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09207164593966936,"gpt":0.4593578928484379,"spread":0.3672862469087685,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001169805,0.0008072581,0.001307724,0.002214051,0.0004873208,0.002430812,0.0008731256,0.002096491,0.00405858],"category_scores_gemma":[0.00127043,0.0003603411,0.000724813,0.001883232,0.001101959,0.004074973,0.001289572,0.003846256,0.002626258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009197477,"about_ca_system_score_gemma":0.001047275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004734791,"about_ca_topic_score_gemma":0.001087421,"domain_scores_codex":[0.9993265,0.000137598,0.00006350191,0.0001206319,0.0002603896,0.0000913723],"domain_scores_gemma":[0.9992663,0.0003046928,0.00009712006,0.00002699078,0.000216122,0.00008877627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001595616,0.0002432952,0.0004112435,0.01163442,0.0001200085,0.000664079,0.0004777258,0.0008412024,0.0165345,0.02622925,0.07237134,0.8703134],"study_design_scores_gemma":[0.00003187145,0.0003733974,0.0003829667,0.001249919,0.00006858656,0.001408714,0.000183704,0.0005449259,0.003722982,0.00862108,0.9833628,0.00004903063],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001106685,0.9862868,0.002531606,0.003802677,0.001741649,0.00002964235,0.00006789537,0.00008997764,0.004343044],"genre_scores_gemma":[0.005199535,0.983245,0.002888916,0.003611919,0.001583319,0.00003252543,0.0001423625,0.00002507998,0.003271386],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00405858,"threshold_uncertainty_score":0.01357728,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4391170020","doi":"10.2174/0113895575270509231121060105","title":"The Search for Antidotes Against Ricin","year":2024,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Univerzita Hradec Králové","keywords":"Ricinoleic acid; Ricin; Ricinus; Castor oil; Biotechnology; Business; Chemistry; Biology; Toxin; Biochemistry","authors":[{"name":"Fernanda D. Botelho","is_ca":false},{"name":"Tanos C. C. França","is_ca":true},{"name":"Steven R. LaPlante","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05341771526644686,"gpt":0.3565450045284134,"spread":0.3031272892619666,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003168085,0.0005243961,0.0007070239,0.001333933,0.0002058407,0.0006035575,0.0004716783,0.0007063998,0.003085493],"category_scores_gemma":[0.0003134494,0.0002272469,0.0004104675,0.0008320398,0.0002768301,0.0009462165,0.0004581002,0.001409711,0.001683571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003371298,"about_ca_system_score_gemma":0.0005028112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003309885,"about_ca_topic_score_gemma":0.0006054493,"domain_scores_codex":[0.9998813,0.00002081606,0.00001179368,0.0000190584,0.00005031018,0.00001678928],"domain_scores_gemma":[0.9999129,0.00003258387,0.00001673237,0.000004130787,0.00002468847,0.000009031885],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001265311,0.0001468289,0.0002319446,0.02725743,0.0001362153,0.0003776473,0.0001156018,0.0006423941,0.02731705,0.01233474,0.02675611,0.9045575],"study_design_scores_gemma":[0.00002277402,0.0002139636,0.0006103225,0.002050256,0.00009348127,0.001197118,0.00004355749,0.0001676376,0.005436885,0.002319556,0.9878283,0.00001612385],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007802426,0.9967006,0.000359509,0.0003714669,0.0002285233,0.00000835539,0.00002332354,0.00001569561,0.00151231],"genre_scores_gemma":[0.003913357,0.9936266,0.0004480802,0.0003603036,0.0001721727,0.00001056383,0.00004655239,0.000003071286,0.001419335],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003085493,"threshold_uncertainty_score":0.01032203,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2323606571","doi":"10.2174/1389557514666141013142436","title":"Investigation on Polymorphic Behavior of Progesterone and Stabilization by Co-Crystallization: A Review","year":2014,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Crystallization and Solubility Studies","field":"Materials Science","cited_by":6,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"","keywords":"Progestogen; Crystallization; Enantiomer; Chemistry; Hormone; Stereochemistry; Biochemistry; Organic chemistry","authors":[{"name":"Anindita Sarkar","is_ca":false},{"name":"Sohrab Rohani","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08161466086158845,"gpt":0.3557238736900314,"spread":0.2741092128284429,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003746783,0.0006530782,0.0009436777,0.002341513,0.0003016671,0.0006419867,0.0005760627,0.0005771189,0.003481033],"category_scores_gemma":[0.0004880581,0.000358882,0.0005294207,0.002255494,0.0002777544,0.0009676389,0.0003708602,0.0006179591,0.001413802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004094332,"about_ca_system_score_gemma":0.0007662479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001062772,"about_ca_topic_score_gemma":0.001720361,"domain_scores_codex":[0.9998261,0.0000246274,0.00002581178,0.00003752384,0.00006971235,0.00001614696],"domain_scores_gemma":[0.9997692,0.000122248,0.000038424,0.000006926039,0.00005217581,0.00001108344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009494236,0.0001233957,0.0004621942,0.05907765,0.0001374878,0.00040078,0.0001573749,0.0008152382,0.01712278,0.004716788,0.01475285,0.9021384],"study_design_scores_gemma":[0.00001338322,0.0002237524,0.001382447,0.003073782,0.0001913053,0.001586383,0.0001142399,0.0003036901,0.01149346,0.001400728,0.9801804,0.0000365021],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007843188,0.9970446,0.0002525867,0.0001211582,0.00006986202,0.00000856621,0.00004413944,0.000009742149,0.001665043],"genre_scores_gemma":[0.002443102,0.996206,0.0004292696,0.00006585744,0.00005548233,0.000009624589,0.00005491616,0.00000258901,0.0007331323],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003481033,"threshold_uncertainty_score":0.0116452,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W25873069","doi":"10.2174/1389557515666150414152933","title":"Organic Agriculture: A Productive Means of Low-carbon and High Biodiversity Food Production","year":2010,"lang":"en","type":"book-chapter","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Agriculture Sustainability and Environmental Impact","field":"Environmental Science","cited_by":6,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Agriculture; Business; Production (economics); Organic farming; Sustainable agriculture; Natural resource economics; Agricultural productivity; Work (physics); Food processing; Population; Biodiversity; Environmental planning; Environmental resource management; Agroforestry; Environmental science; Geography; Engineering; Economics; Political science; Ecology","authors":[{"name":"U. Niggli","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.007551013693933495,"gpt":0.189666946839392,"spread":0.1821159331454585,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008243684,0.0005047844,0.0002859255,0.0007110752,0.000339085,0.001272942,0.0004285192,0.0005601029,0.0117956],"category_scores_gemma":[0.00007198248,0.0001253193,0.0001575324,0.00114775,0.0004056088,0.00104696,0.0005263278,0.000600401,0.004927935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005419013,"about_ca_system_score_gemma":0.0006234822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003508882,"about_ca_topic_score_gemma":0.001063112,"domain_scores_codex":[0.9999529,0.000003954825,0.000001839975,0.00001126466,0.00002495049,0.000005179211],"domain_scores_gemma":[0.9999747,0.000007388747,0.000005482312,0.000002013908,0.000005355232,0.000005076483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006168883,0.0001108582,0.0003168999,0.003045839,0.00001963725,0.0004505491,0.0002411425,0.0009248054,0.04446319,0.06554125,0.0590938,0.8257304],"study_design_scores_gemma":[0.000006145286,0.0000374545,0.0004181653,0.0002063071,0.000006615691,0.0004602637,0.00005840564,0.0001161529,0.003683381,0.01139912,0.9836014,0.000006740933],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01677869,0.5817908,0.02080879,0.006281839,0.002937205,0.00008652459,0.0005181835,0.0006908313,0.3701071],"genre_scores_gemma":[0.08238599,0.5637847,0.03361285,0.002309793,0.001910344,0.00009199428,0.0007451882,0.0001911551,0.3149679],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0117956,"threshold_uncertainty_score":0.03946024,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2320371219","doi":"10.2174/1389557511313040001","title":"Structure and Thermodynamics of Drug-RNA Aptamer Interactions","year":2013,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Waterloo","funders":"","keywords":"Aptamer; Isothermal titration calorimetry; RNA; Nucleic acid structure; Chemistry; Computational biology; Thermodynamics; Biology; Biochemistry; Physics; Molecular biology","authors":[{"name":"Jason Bernard Da Costa","is_ca":true},{"name":"Thorsten Dieckmann","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02334229213764334,"gpt":0.3112004211512615,"spread":0.2878581290136181,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004697872,0.0007105613,0.001006664,0.0005064353,0.0002037203,0.0005507738,0.000763412,0.0007671568,0.002095133],"category_scores_gemma":[0.0004652423,0.0003818203,0.0004499535,0.0004631348,0.0004725126,0.0008829079,0.0004335094,0.0008682891,0.001369506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007583743,"about_ca_system_score_gemma":0.0005098162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005471478,"about_ca_topic_score_gemma":0.0005015471,"domain_scores_codex":[0.9996518,0.000069021,0.00002579097,0.00007582346,0.0001450646,0.00003263678],"domain_scores_gemma":[0.9998685,0.00006803693,0.00002722499,0.000005799111,0.0000250926,0.000005346147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001396812,0.000116883,0.0006371569,0.02183376,0.0001498837,0.0003676923,0.0001921061,0.006904446,0.4402678,0.02556524,0.006482447,0.4973428],"study_design_scores_gemma":[0.00002679726,0.0006462039,0.003585174,0.0009176031,0.0001874172,0.002920395,0.0001163289,0.006329681,0.5430073,0.01020255,0.4319244,0.0001361943],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01417327,0.9657498,0.009449431,0.0004470149,0.0004330109,0.00005102245,0.0001529062,0.00009277998,0.009450809],"genre_scores_gemma":[0.1068107,0.8770262,0.007527652,0.000490792,0.0005094712,0.0001318784,0.0002688928,0.00004520144,0.00718925],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002095133,"threshold_uncertainty_score":0.00700891,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4311200937","doi":"10.2174/1389557523666221207155909","title":"The Role of Genetics and Synergistic Effect of Targeting Common GeneticMutations in Acute Lymphoblastic Leukemia (ALL)","year":2022,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Brock University","funders":"","keywords":"Lymphoblastic Leukemia; Genetics; Mutation; Biology; Cancer research; Medicine; Leukemia; Gene","authors":[{"name":"Niloofar Pilehvari","is_ca":false},{"name":"Maryam Katoueezadeh","is_ca":true},{"name":"Gholamhossein Hassanshahi","is_ca":false},{"name":"Seyedeh Atekeh Torabizadeh","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02163836644902219,"gpt":0.3429304732559673,"spread":0.3212921068069451,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002906022,0.0004487312,0.0007261104,0.0009918347,0.0001492311,0.0006152009,0.0004523467,0.000571362,0.002981069],"category_scores_gemma":[0.0002661998,0.0001635835,0.0004150229,0.0008248637,0.0002668603,0.0005682516,0.0004019612,0.001012295,0.001025183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003050579,"about_ca_system_score_gemma":0.0004304937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003993448,"about_ca_topic_score_gemma":0.0008870647,"domain_scores_codex":[0.9998972,0.00002239996,0.00001095848,0.00001911969,0.00003444004,0.00001586131],"domain_scores_gemma":[0.9999169,0.00004001843,0.0000141136,0.0000032592,0.00001753442,0.000008244751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001661124,0.0001276681,0.0002944607,0.01870751,0.000140034,0.0003990176,0.00008629245,0.0006623431,0.01243151,0.006392525,0.01575836,0.9448342],"study_design_scores_gemma":[0.00004274576,0.0005348495,0.001515373,0.002192071,0.0002215931,0.002134978,0.00007015638,0.0002027241,0.005400006,0.002815956,0.9848433,0.00002625586],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007181328,0.9973546,0.0002121803,0.0002174284,0.0001312229,0.000008074761,0.00003332509,0.00001016317,0.001314914],"genre_scores_gemma":[0.003436915,0.9951975,0.0002739011,0.0001825657,0.00008014003,0.00001109763,0.00004907414,0.000002063853,0.0007667129],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002981069,"threshold_uncertainty_score":0.009972632,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2079117034","doi":"10.2174/138955706775476000","title":"Proteomics in Medicinal Chemistry","year":2006,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":3,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Canadian Institute for Theoretical Astrophysics; Texas Tech University","keywords":"Stable isotope labeling by amino acids in cell culture; Proteomics; Mass spectrometry; Chemistry; Quantitative proteomics; Computational biology; Drug discovery; Chromatography; Biochemistry; Biology","authors":[{"name":"Satomi Niwayama","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04121650527500058,"gpt":0.3620551095531651,"spread":0.3208386042781645,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001743598,0.001916622,0.002561792,0.002734812,0.000809732,0.002864064,0.002204855,0.003299343,0.01427999],"category_scores_gemma":[0.001355218,0.0006106095,0.0006592262,0.003895561,0.002700272,0.004448992,0.002307972,0.005333599,0.02288474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001615254,"about_ca_system_score_gemma":0.001641853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005308953,"about_ca_topic_score_gemma":0.0007566711,"domain_scores_codex":[0.9987258,0.0002274866,0.00009545788,0.0002026512,0.0006528622,0.00009565326],"domain_scores_gemma":[0.9991062,0.0002886224,0.0001010956,0.0001147164,0.0002406139,0.0001487187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007665314,0.0001465169,0.0001257195,0.008596308,0.00008620349,0.000392239,0.0001764687,0.0007208657,0.00725703,0.05525168,0.117161,0.8100094],"study_design_scores_gemma":[0.0000164947,0.00007749459,0.0001466687,0.0008558116,0.00001348615,0.0008275373,0.00002603538,0.0001204205,0.0007727717,0.01130164,0.985826,0.00001566439],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002906992,0.9694397,0.004282364,0.002464439,0.004692473,0.00005159212,0.00005616012,0.0001293975,0.01859318],"genre_scores_gemma":[0.003899829,0.9593362,0.006857556,0.004377078,0.005119785,0.00007714953,0.0001411198,0.00003011542,0.02016123],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01427999,"threshold_uncertainty_score":0.04777133,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2154682695","doi":"10.2174/138955709789957369","title":"Ligands of Diltiazem Binding Site: An Overview of Some Chemotypes","year":2009,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Chemical synthesis and alkaloids","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Diltiazem; Chemotype; Binding site; Chemistry; Computational biology; Stereochemistry; Combinatorial chemistry; Calcium; Biology; Biochemistry; Organic chemistry","authors":[{"name":"Roberta Budriesi","is_ca":false},{"name":"Pierfranco Ioan","is_ca":false},{"name":"Emanuele Carosati","is_ca":false},{"name":"Gabriele Cruciani","is_ca":false},{"name":"Boris S. Zhorov","is_ca":false},{"name":"Alberto Chiarini","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1012502604695122,"gpt":0.3743827798086485,"spread":0.2731325193391364,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001942319,0.0006545185,0.0008933234,0.001121062,0.0001788814,0.0003498109,0.0006097982,0.0004586509,0.003472853],"category_scores_gemma":[0.0002215507,0.0002613488,0.0003121387,0.0009819476,0.0002075567,0.0004217172,0.0002697861,0.0005772425,0.002038745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005630093,"about_ca_system_score_gemma":0.000407462,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009479762,"about_ca_topic_score_gemma":0.001889202,"domain_scores_codex":[0.9999113,0.00001379936,0.000009492004,0.0000222038,0.00002840743,0.00001474692],"domain_scores_gemma":[0.9999346,0.00002311086,0.00001432455,0.000003750288,0.00001596458,0.000008279187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003560558,0.0001805961,0.0004395075,0.0143065,0.0001173442,0.0007516387,0.00009384188,0.003421667,0.1542409,0.006350913,0.01107881,0.8086623],"study_design_scores_gemma":[0.000195078,0.0009054226,0.002617171,0.001304168,0.0002653255,0.003989176,0.00008282477,0.00144059,0.08402821,0.002363184,0.9027215,0.0000873142],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006934527,0.9816394,0.002806672,0.0003644103,0.000126145,0.00005905389,0.0002618553,0.0001201335,0.007687777],"genre_scores_gemma":[0.02900139,0.960375,0.004354172,0.0004123494,0.000119019,0.00008736418,0.0004651704,0.0000157544,0.005169788],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003472853,"threshold_uncertainty_score":0.0116179,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4229980849","doi":"10.2174/138955752013200626153850","title":"Meet Our Editorial Board Member","year":2020,"lang":"en","type":"article","venue":"Mini-Reviews in Medicinal Chemistry","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Editorial board; Business; Computer science; Library science","authors":[{"name":"Frank Wuest","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02862264732122805,"gpt":0.3199465409947839,"spread":0.2913238936735558,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003190666,0.001912182,0.001464982,0.002143443,0.001993627,0.00681134,0.001363885,0.007883025,0.2580527],"category_scores_gemma":[0.01746281,0.0006943468,0.001014659,0.0007130576,0.0007726453,0.002734301,0.002420814,0.005981288,0.2382474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001137471,"about_ca_system_score_gemma":0.002608818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004578338,"about_ca_topic_score_gemma":0.0018681,"domain_scores_codex":[0.9973618,0.0003776304,0.0001817052,0.000361457,0.00140307,0.0003143261],"domain_scores_gemma":[0.9854118,0.001340896,0.001121272,0.0004370889,0.006115104,0.0055738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002810533,0.00001332601,0.00004516574,0.00005815118,0.000003741746,0.00007521117,0.00000567658,0.00001167784,0.0001657828,0.0001221605,0.9848036,0.01466754],"study_design_scores_gemma":[0.00002656296,0.00002367363,0.0002246513,0.00006300648,0.000006933665,0.0001823071,0.00004130927,0.00005395869,0.0001060688,0.0003351397,0.9989266,0.000009674492],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.0006067531,0.008659832,0.001121728,0.1074984,0.826411,0.0002930675,0.0003435787,0.0007378522,0.05432778],"genre_scores_gemma":[0.002770604,0.005261392,0.001073026,0.06187604,0.4732737,0.0003094015,0.0003889842,0.0004569806,0.4545899],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.2580527,"threshold_uncertainty_score":0.8632724,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4388711107","doi":"10.2174/138955752405231109211935","title":"Meet the Editorial Board Member","year":2023,"lang":"en","type":"article","venue":"Mini-Reviews in Medicinal Chemistry","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Editorial board; Business; Computer science; Library science","authors":[{"name":"Frank Wuest","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02367901253211854,"gpt":0.3248242213626523,"spread":0.3011452088305338,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003277427,0.001671982,0.001464537,0.001817448,0.001777258,0.005904309,0.001340251,0.0086108,0.2263035],"category_scores_gemma":[0.01548304,0.0006787614,0.0009631751,0.0005693918,0.000702411,0.002379459,0.002119913,0.005881239,0.2065627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001153479,"about_ca_system_score_gemma":0.00256805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004977408,"about_ca_topic_score_gemma":0.001717513,"domain_scores_codex":[0.9974632,0.0003878506,0.0001766843,0.000359909,0.001322439,0.0002898436],"domain_scores_gemma":[0.9879537,0.001179166,0.000948387,0.0003743137,0.005527017,0.004017397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003404538,0.00001192173,0.00004887559,0.00006107888,0.000003768849,0.00008434088,0.000005587917,0.00001226239,0.0001737226,0.0001293391,0.9870263,0.01240884],"study_design_scores_gemma":[0.00003065767,0.00002645956,0.0002888749,0.00007472189,0.000007378655,0.0001721754,0.00004568455,0.00007754561,0.000114124,0.0003382092,0.9988136,0.00001056223],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.0005776596,0.006444882,0.0009198077,0.1210985,0.8150239,0.0003269174,0.0003475294,0.0005463001,0.05471448],"genre_scores_gemma":[0.003232897,0.004652651,0.0008569809,0.06387182,0.4354458,0.0003600318,0.0004097047,0.0003588746,0.4908112],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.2263035,"threshold_uncertainty_score":0.7570607,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4410965407","doi":"10.2174/0113895575343984250519051357","title":"Innovations in Cannabis Delivery Systems: A Patent Review (2012-2024)","year":2025,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Cannabis; Drug delivery; Medicine; Cannabis sativa; Pharmacology; Biotechnology; Business; Psychiatry; Nanotechnology; Biology","authors":[{"name":"A. Casas","is_ca":false},{"name":"Vanessa Lima","is_ca":false},{"name":"Nicolas Redondo","is_ca":false},{"name":"Izabel Almeida Alves","is_ca":false},{"name":"Diana Marcela Aragón","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2108121982795275,"gpt":0.4782511294350402,"spread":0.2674389311555126,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003331505,0.0009403072,0.002062681,0.01369554,0.0005580266,0.001670147,0.001120676,0.001498121,0.01085739],"category_scores_gemma":[0.007253803,0.0003902209,0.003297089,0.01226805,0.0004986937,0.002109951,0.0009006346,0.0008029473,0.001478127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002587667,"about_ca_system_score_gemma":0.007498211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004039633,"about_ca_topic_score_gemma":0.007576044,"domain_scores_codex":[0.9982921,0.0003075009,0.0004769047,0.0001540539,0.0006175913,0.0001518558],"domain_scores_gemma":[0.9945551,0.002707493,0.001358595,0.0000901998,0.001165664,0.0001228872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004288688,0.00007063335,0.0006215644,0.3502574,0.0007625057,0.0008813124,0.0002166071,0.0003020868,0.002170307,0.002501982,0.01947581,0.6223109],"study_design_scores_gemma":[0.0003931587,0.001041725,0.0103494,0.2931895,0.01219784,0.003462916,0.0004189859,0.0003765285,0.002865348,0.001754251,0.6738603,0.00008997625],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001316238,0.9945695,0.0001999053,0.0006349991,0.000179336,0.0001779007,0.0006447241,0.0000156272,0.002261759],"genre_scores_gemma":[0.007118408,0.9904346,0.0004842798,0.0004362203,0.000119614,0.0001134866,0.0005987334,0.000004824859,0.0006899227],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01369554,"threshold_uncertainty_score":0.03632164,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}