{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":272,"total_is_capped":false,"direct_labels_cover":1,"predictions_cover":272,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"query_hash":"d49772a2c02e","filters":{"venue":"Molecular Brain"}},"results":[{"id":"W2800776893","doi":"10.1186/s13041-018-0357-8","title":"Targeting NMDA receptors in stroke: new hope in neuroprotection","year":2018,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":323,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; University Health Network","funders":"Canada Research Chairs","keywords":"Neuroprotection; NMDA receptor; Neuroscience; Stroke (engine); Neurology; Receptor; Medicine; Excitotoxicity; Psychopharmacology; Pharmacology; Psychology; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.0713625066069485,"gpt":0.3844366366639655,"spread":0.313074130057017,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000960456,0.0005387329,0.0009996952,0.001288155,0.0001341612,0.0001351239,0.001196297,0.0003313864,0.0001462498],"category_scores_gemma":[0.004287995,0.0005145549,0.0002800043,0.002940641,0.0002878941,0.0002154918,0.0004807952,0.001905018,0.0004915813],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001786099,"about_ca_system_score_gemma":0.0005984368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006054783,"about_ca_topic_score_gemma":0.00001277618,"domain_scores_codex":[0.9929396,0.002841349,0.0008075369,0.001720935,0.000646117,0.001044487],"domain_scores_gemma":[0.9984113,0.0005352701,0.0002750111,0.0005197933,0.00002225788,0.0002363649],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003044088,0.0001613731,0.000009911568,0.001287366,0.00000424609,0.002526656,0.00006269335,0.0000284728,0.5916884,0.00003908747,0.005828524,0.3983329],"study_design_scores_gemma":[0.0004808438,0.0002247256,0.000001693754,0.001057314,0.00001470471,0.0000791411,0.000003195759,0.00008821696,0.07277029,0.00003836116,0.9247437,0.0004978053],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01459111,0.9742169,0.0002469594,0.001018837,0.003434416,0.00523921,0.00002952656,0.0002487303,0.0009742856],"genre_scores_gemma":[0.0002331889,0.9948236,0.00003962695,0.001780877,0.0002242682,0.0001869134,0.000003708765,0.0001453623,0.002562446],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9189152,"threshold_uncertainty_score":0.9997306,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2121981334","doi":"10.1186/1756-6606-2-5","title":"Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo","year":2009,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":281,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; Academy of Finland; Canada Research Chairs; European Commission","keywords":"Cathepsin D; Alpha-synuclein; Biology; Cell biology; Molecular biology; Gene expression; Biochemistry; Gene; Enzyme; Parkinson's disease; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.01440826121371857,"gpt":0.2688224786398973,"spread":0.2544142174261788,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001375048,0.0001736549,0.0002164793,0.0001243392,0.00006312034,0.00002941219,0.00005069324,0.00009006089,0.00004070509],"category_scores_gemma":[0.0001081342,0.0001525842,0.00004910521,0.0001704739,0.00002562245,0.00008171045,0.00002245845,0.00008726033,0.000006346765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006315525,"about_ca_system_score_gemma":0.0000641023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001791695,"about_ca_topic_score_gemma":0.000009072162,"domain_scores_codex":[0.9989971,0.00006453827,0.0001332391,0.0003473626,0.0002252136,0.000232563],"domain_scores_gemma":[0.9995259,0.00001555141,0.00005890246,0.0001994762,0.0000279639,0.0001722159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008725734,0.0004352271,0.001662639,0.00004304624,0.00001218263,0.0008195595,0.0002161897,0.000003321713,0.9533581,0.0001532339,0.0007630601,0.04244623],"study_design_scores_gemma":[0.002773357,0.0002594525,0.04259429,0.0003795264,0.00003592771,0.00004434686,0.00002328107,0.0004645156,0.9509069,0.001441687,0.0009088204,0.0001678426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993367,0.001031531,0.002657789,0.001621323,0.00001914426,0.0004106454,0.00001031065,0.00005189775,0.0008303636],"genre_scores_gemma":[0.9947141,0.00001245334,0.002761712,0.002119116,0.00001990514,0.0000235968,0.00001501632,0.00001957966,0.0003145585],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04227839,"threshold_uncertainty_score":0.6222204,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2114735161","doi":"10.1186/1756-6606-4-31","title":"Neuronal and microglial mechanisms of neuropathic pain","year":2011,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":258,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Canada Research Chairs","funders":"Canadian Institutes of Health Research","keywords":"Neuropathic pain; Neuroscience; Neuroplasticity; Nerve injury; Microglia; Medicine; Synaptic plasticity; Chronic pain; Peripheral nerve injury; Neuralgia; Nociception; Psychology; Anesthesia; Receptor; Inflammation; Sciatic nerve; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.02825727764033015,"gpt":0.2865462374822283,"spread":0.2582889598418982,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001505593,0.0004253829,0.001396165,0.0001927235,0.00003322708,0.0000102507,0.0001300358,0.0002877463,0.00005709026],"category_scores_gemma":[0.000500852,0.0003442775,0.0004492366,0.0001397243,0.00006169084,0.00001538149,0.0001086763,0.0003211478,0.00002310192],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002491847,"about_ca_system_score_gemma":0.0001722678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001411095,"about_ca_topic_score_gemma":6.10019e-7,"domain_scores_codex":[0.9972255,0.00134448,0.0004459133,0.0004974958,0.0002126667,0.0002739971],"domain_scores_gemma":[0.9988755,0.0002143837,0.0002453375,0.0004485962,0.00003957278,0.0001765931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001151619,0.0001517567,0.000001032615,0.007541587,0.0002599569,0.001248625,0.00001931477,9.782371e-9,0.005125594,0.006177829,0.00007318983,0.9793896],"study_design_scores_gemma":[0.002083183,0.002177874,0.00001102986,0.01647705,0.004988916,0.001859097,0.00001024479,0.00004769751,0.007061875,0.007163364,0.9571341,0.0009855854],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005605508,0.9709343,0.02764574,0.00005919365,0.0001115808,0.0008450667,0.00005368099,0.00003714303,0.0002572021],"genre_scores_gemma":[0.0002058781,0.9939231,0.003789401,0.001267993,0.00004482502,0.00006468797,0.0001181576,0.0001371442,0.0004488251],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.978404,"threshold_uncertainty_score":0.9999009,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2935973331","doi":"10.1186/s13041-019-0442-7","title":"Structural plasticity of the hippocampus in response to estrogens in female rodents","year":2019,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":193,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Guelph; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Neurogenesis; Hippocampal formation; Hippocampus; Neuroplasticity; Neuroscience; Estrogen; Dendritic spine; Estrous cycle; Dentate gyrus; Biology; Hormone; Endocrinology; Internal medicine; Psychology; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.05680282487419904,"gpt":0.3218517410859361,"spread":0.265048916211737,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003839756,0.0004676548,0.001196499,0.0004671562,0.00004460396,0.00003796943,0.001117782,0.0002076353,0.00001806276],"category_scores_gemma":[0.004124589,0.0003544497,0.0004163022,0.001309006,0.00007038832,0.00004056544,0.0005793441,0.0005261776,0.00006967775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001196239,"about_ca_system_score_gemma":0.0002917134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001198186,"about_ca_topic_score_gemma":0.00002239976,"domain_scores_codex":[0.9946649,0.002519545,0.0007630753,0.0009348117,0.0005953429,0.0005223324],"domain_scores_gemma":[0.9974316,0.001409569,0.0003181977,0.0007130047,0.00001803047,0.0001095999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002542683,0.0001436314,0.00008040484,0.002718003,0.00001404857,0.001078801,0.0001449548,0.001333788,0.9455388,0.0006031711,0.00002768613,0.04806251],"study_design_scores_gemma":[0.002010915,0.0007099415,0.001390334,0.01369218,0.000289374,0.0005612063,0.00001908917,0.0004443187,0.9422151,0.0003507677,0.03643902,0.001877777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9375034,0.06013376,0.00003245974,0.00006516029,0.0005204951,0.001593104,0.0001140521,0.00001768804,0.00001990367],"genre_scores_gemma":[0.8712757,0.1254555,0.0001024821,0.002338914,0.00004654738,0.0001981099,0.00000572521,0.0003092959,0.0002676547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06622764,"threshold_uncertainty_score":0.9998907,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2045344243","doi":"10.1186/1756-6606-2-4","title":"Plasticity of NMDA receptor NR2B subunit in memory and chronic pain","year":2009,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":181,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Neuroscience; NMDA receptor; Long-term potentiation; AMPA receptor; Synaptic plasticity; Metaplasticity; Psychology; Neuroplasticity; Glutamatergic; Chronic pain; Glutamate receptor; Receptor; Biology; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.06240970843761947,"gpt":0.3729602374373366,"spread":0.3105505289997171,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001071632,0.0004076513,0.001125739,0.0006177373,0.00008753191,0.00004074694,0.0007982536,0.0002437853,0.00008605247],"category_scores_gemma":[0.003223322,0.0003703088,0.0002096074,0.001267091,0.0005665725,0.00009207585,0.0002795247,0.000976698,0.00004677688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009988881,"about_ca_system_score_gemma":0.0005056827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006421302,"about_ca_topic_score_gemma":0.000004577519,"domain_scores_codex":[0.9940388,0.003212989,0.0005881093,0.001011675,0.00049563,0.000652779],"domain_scores_gemma":[0.9972813,0.001916436,0.0002418156,0.0003571242,0.0000232189,0.0001801187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000008947602,0.00009947226,9.904297e-7,0.002110553,0.000003471752,0.0003433372,0.0000144065,0.000003713903,0.5155643,0.00007082124,0.0004263328,0.4813536],"study_design_scores_gemma":[0.0007867504,0.000880254,0.000006172293,0.003147312,0.00005713014,0.0000894216,0.000003877093,0.000146977,0.4287644,0.00007473123,0.5653514,0.0006916092],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0296039,0.9673556,0.00008656033,0.0003511425,0.0002449896,0.001836805,0.00006622384,0.00006526388,0.0003894808],"genre_scores_gemma":[0.001679407,0.9963967,0.00001513217,0.00130904,0.0000487356,0.00006909054,0.000002822921,0.00005605839,0.0004230097],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.564925,"threshold_uncertainty_score":0.9998749,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2167928721","doi":"10.1186/1756-6606-2-35","title":"Abnormalities in brain structure and behavior in GSK-3alpha mutant mice","year":2009,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":179,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University; University of Toronto; Hospital for Sick Children; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; Centre for Addiction and Mental Health","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Neurochemical; GSK-3; Neuroscience; Fear conditioning; Motor coordination; Mutant; Aversive Stimulus; Psychology; Biology; Kinase; Amygdala; Gene; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.004528521180050973,"gpt":0.2339264316191463,"spread":0.2293979104390953,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000224058,0.0002067747,0.0001790843,0.0001158271,0.00003286039,0.00003649865,0.0001744986,0.0002010519,0.00003265625],"category_scores_gemma":[0.00007600286,0.0002148587,0.00004610926,0.0001632567,0.00006204657,0.000007132858,0.00006281793,0.00015291,0.000001620385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002917422,"about_ca_system_score_gemma":0.00007055012,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005203571,"about_ca_topic_score_gemma":0.0001747464,"domain_scores_codex":[0.9987713,0.0000905294,0.0002577408,0.0003986762,0.0001439939,0.0003377851],"domain_scores_gemma":[0.9996465,0.00001374032,0.00005088848,0.00019697,0.00002670952,0.00006516194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004630455,0.0000419093,0.007504095,0.00001162508,0.000008937996,0.0001275212,0.0002301031,0.00004897225,0.9882925,0.0001445897,0.000512928,0.003030475],"study_design_scores_gemma":[0.00131963,0.0001802246,0.06038186,0.00003973799,0.00001071687,0.00006060841,0.0001077052,0.00003344697,0.9338681,0.000699199,0.002869672,0.0004291291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962578,0.001539365,0.0001612872,0.001430371,0.00006518765,0.0002212379,0.00001540641,0.0000115719,0.0002977467],"genre_scores_gemma":[0.9952069,0.00003855997,0.0007068602,0.003461279,0.00005105965,0.00002433738,0.0001016075,0.00002035769,0.0003890393],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05442447,"threshold_uncertainty_score":0.8761685,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2184646443","doi":"10.1186/s13041-015-0170-6","title":"Bidirectional modulation of hyperalgesia via the specific control of excitatory and inhibitory neuronal activity in the ACC","year":2015,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":173,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Ministry of Education, Science and Technology; National Research Foundation of Korea; Canada Excellence Research Chairs, Government of Canada; National Research Foundation","keywords":"Optogenetics; Inhibitory postsynaptic potential; Neuroscience; Excitatory postsynaptic potential; Nociception; Parvalbumin; Anterior cingulate cortex; Channelrhodopsin; Hyperalgesia; Chemistry; Psychology; Medicine; Receptor; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.01915961266494276,"gpt":0.2489053509598409,"spread":0.2297457382948981,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004792118,0.00006875068,0.0001285633,0.00005094548,0.00001954468,0.000003561233,0.00003992977,0.00003595895,0.000004221127],"category_scores_gemma":[0.00006019679,0.00004211847,0.00003960151,0.00009406253,0.00006430534,0.00002912715,0.0000109707,0.00008403843,8.736575e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002190463,"about_ca_system_score_gemma":0.0000398429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003391302,"about_ca_topic_score_gemma":0.000003681072,"domain_scores_codex":[0.9992205,0.0002368979,0.0001102257,0.0001080316,0.0002495001,0.00007483793],"domain_scores_gemma":[0.999615,0.0001068225,0.00005772771,0.000149693,0.00004010378,0.0000306527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001688046,0.0001972461,0.008038318,0.00001241563,0.00003970116,0.00002964544,0.0003219839,0.0000766696,0.9855497,0.0008237276,0.000159535,0.004582272],"study_design_scores_gemma":[0.004049801,0.0003432466,0.9160222,0.00002966118,0.00004152591,0.00004781779,0.000123168,0.003444686,0.07288039,0.002633043,0.0003092344,0.00007526114],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917621,0.0003002245,0.006048222,0.001397688,0.0000444078,0.0002715321,0.000003818493,0.000004582852,0.0001674028],"genre_scores_gemma":[0.9993768,0.000003596267,0.000138175,0.0004134215,0.00002872325,0.00001294392,0.000003736101,0.00000718174,0.00001544361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9126693,"threshold_uncertainty_score":0.1717542,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2127122830","doi":"10.1186/1756-6606-6-26","title":"Altered microRNA expression profile in amyotrophic lateral sclerosis: a role in the regulation of NFL mRNA levels","year":2013,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":164,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"London Health Sciences Centre; Western University","funders":"Canadian Institutes of Health Research; ALS Society of Canada","keywords":"microRNA; Amyotrophic lateral sclerosis; Biology; Dicer; Messenger RNA; Untranslated region; Three prime untranslated region; Gene expression; Neuroscience; Bioinformatics; RNA; Genetics; Disease; Gene; Pathology; RNA interference; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.02697856244817995,"gpt":0.272728775684095,"spread":0.245750213235915,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005305684,0.0001831315,0.0003206377,0.0002527375,0.00003629827,0.00004094715,0.0002743279,0.0001381938,0.000393967],"category_scores_gemma":[0.0001607083,0.0001271844,0.00009900565,0.0005125354,0.00009985766,0.0001620543,0.0001101855,0.0003820074,0.00006436004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001057708,"about_ca_system_score_gemma":0.0000659846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006002145,"about_ca_topic_score_gemma":0.00002200787,"domain_scores_codex":[0.99769,0.0004488571,0.0004881744,0.0003540086,0.0005815262,0.000437416],"domain_scores_gemma":[0.9991058,0.00006234821,0.0001107456,0.0005375025,0.00009532412,0.00008825338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00008346022,0.0001614839,0.006203053,0.000045677,0.00001025148,0.00001776141,0.0008725464,0.00005836798,0.9891294,0.00004436068,0.001094967,0.002278683],"study_design_scores_gemma":[0.001791468,0.0001447783,0.7684834,0.000517913,0.000004999922,0.00001063466,0.00006964619,0.001866253,0.2261939,0.0007446395,0.00005911857,0.000113277],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873057,0.0002058559,0.00007200033,0.01056339,0.00002618497,0.001405755,0.000006200452,0.00001943214,0.0003954997],"genre_scores_gemma":[0.9968818,0.000009087319,0.0009898365,0.0015919,0.00003842619,0.0002418861,0.00003113849,0.00003360942,0.0001823234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7629355,"threshold_uncertainty_score":0.5186429,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2146531447","doi":"10.1186/1756-6606-4-21","title":"Transcriptional dysregulation of 5-HT1A autoreceptors in mental illness","year":2011,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":155,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; University of Toronto; Canadian Psychiatric Research Foundation; Centre for Addiction and Mental Health; Heart and Stroke Foundation of Canada","keywords":"Serotonergic; Autoreceptor; 5-HT1A receptor; Neuroscience; Serotonin; Biology; Neurotransmission; 5-HT receptor; Receptor; Cell biology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.0638386586086307,"gpt":0.3323881359784136,"spread":0.2685494773697829,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002640136,0.0005389208,0.001115376,0.0006021791,0.00005164589,0.00003342139,0.0007513561,0.0003368966,0.0007104674],"category_scores_gemma":[0.00009335102,0.0005292048,0.000611677,0.0008233883,0.0002728337,0.0002144243,0.00005723834,0.0004703138,0.0001183386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001539912,"about_ca_system_score_gemma":0.0001730799,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001903568,"about_ca_topic_score_gemma":0.000003821257,"domain_scores_codex":[0.9964058,0.000775584,0.0009728643,0.0008752254,0.0005473754,0.0004231155],"domain_scores_gemma":[0.9989009,0.0000986936,0.0003646906,0.0005000492,0.00002400868,0.0001116077],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001243192,0.0002691043,0.00001829661,0.00228951,0.00001259771,0.00008414414,0.0005663135,0.000003096788,0.2002509,0.003918032,0.00008952771,0.792486],"study_design_scores_gemma":[0.0005625467,0.00008868309,0.00006736352,0.003624386,0.0001447734,0.0001028276,0.00001190113,0.00000639228,0.08380345,0.000203624,0.9104872,0.0008968007],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03083283,0.9623871,0.0003887559,0.0001068201,0.001511206,0.003405537,0.000401833,0.0001620272,0.000803887],"genre_scores_gemma":[0.01042342,0.9875544,0.0002738219,0.0003944141,0.00005504715,0.0005473201,0.0001453525,0.0002608802,0.0003453069],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9103977,"threshold_uncertainty_score":0.9997159,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2102388483","doi":"10.1186/1756-6606-7-40","title":"Metabotropic glutamate receptor 5 knockout reduces cognitive impairment and pathogenesis in a mouse model of Alzheimer's disease","year":2014,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":138,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Metabotropic glutamate receptor 5; Metabotropic glutamate receptor; Knockout mouse; Glutamate receptor; Neuroscience; Phosphorylation; Pathogenesis; PI3K/AKT/mTOR pathway; Metabotropic glutamate receptor 1; Cell biology; Biology; Receptor; Medicine; Signal transduction; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.03464364663679478,"gpt":0.3139867906923571,"spread":0.2793431440555623,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003495472,0.0001845021,0.0002536601,0.0002384181,0.00009363906,0.00003383898,0.0002578281,0.00004230346,0.00001609925],"category_scores_gemma":[0.0008769795,0.0001720324,0.00007474066,0.0003475987,0.0003987207,0.0001340846,0.0002191905,0.0001622852,0.00001443123],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001089828,"about_ca_system_score_gemma":0.00008728779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004894301,"about_ca_topic_score_gemma":6.742648e-7,"domain_scores_codex":[0.9974903,0.0007835593,0.0002625079,0.0006626442,0.0003782367,0.0004227859],"domain_scores_gemma":[0.9991865,0.0002281819,0.00008945938,0.0002117812,0.00003588532,0.0002482446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000155023,0.0002071976,0.0002008515,0.00001626631,0.000004644855,0.00006342727,0.00009008587,0.0003155192,0.9970894,0.0001966301,0.00002174078,0.001639167],"study_design_scores_gemma":[0.0008168316,0.0001903078,0.0008781829,0.00001713314,0.00002674538,0.000003062385,0.00001098871,0.01752543,0.9801769,0.000186503,0.00001323482,0.0001546644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978892,0.0001471928,0.0002623747,0.0009779737,0.00006375906,0.0004927351,0.00008924276,0.00003194081,0.00004562084],"genre_scores_gemma":[0.9972424,0.0001211954,0.0000737749,0.002294245,0.00001154576,0.00008613752,9.311627e-7,0.00002781652,0.0001419778],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01720992,"threshold_uncertainty_score":0.7015277,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2143782901","doi":"10.1186/s13041-015-0102-5","title":"TRPM7 inhibitor carvacrol protects brain from neonatal hypoxic-ischemic injury","year":2015,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Magnesium in Health and Disease","field":"Nursing","cited_by":137,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; China Scholarship Council; University of Toronto; Scottish Rite Charitable Foundation of Canada; Heart and Stroke Foundation of Canada","keywords":"Carvacrol; Neuroprotection; Pharmacology; Medicine; Apoptosis; Anesthesia; Neuroscience; Biology; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.01220039946285399,"gpt":0.2687774359217148,"spread":0.2565770364588608,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004236441,0.0003383725,0.0003088403,0.0001346604,0.0001195807,0.00009109871,0.0003346281,0.0002534791,0.0001284305],"category_scores_gemma":[0.002026585,0.0003593507,0.0001480525,0.0003062391,0.0000932246,0.0001674108,0.0001291381,0.0003674261,0.000335654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000162432,"about_ca_system_score_gemma":0.0002820984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008263225,"about_ca_topic_score_gemma":0.00003810575,"domain_scores_codex":[0.9973007,0.0003508155,0.0004120977,0.0006448265,0.0005912235,0.0007003329],"domain_scores_gemma":[0.9979389,0.0001440311,0.0001323077,0.0006910097,0.0001113188,0.0009824749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001561241,0.0001571343,0.0006640407,0.0002283314,0.0000154363,0.000411427,0.001221648,0.00002060168,0.8011823,0.00006595864,0.164323,0.03014892],"study_design_scores_gemma":[0.004096298,0.0005827931,0.0006968697,0.00006363969,0.00005300376,0.00002521932,0.000260261,0.0008579934,0.9038163,0.003012629,0.08568638,0.0008486388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9764586,0.001435907,0.0007480268,0.01703508,0.0009982081,0.001083417,0.0001838216,0.0002798978,0.001777018],"genre_scores_gemma":[0.9796398,1.92084e-7,0.001323057,0.01766624,0.0006419681,0.0001766875,0.0001795578,0.00008673452,0.0002857375],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.102634,"threshold_uncertainty_score":0.9998859,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2608502625","doi":"10.1186/s13041-017-0293-z","title":"Targeting metabotropic glutamate receptors for novel treatments of schizophrenia","year":2017,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":127,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Canadian Institutes of Health Research; Vanderbilt University","keywords":"Metabotropic glutamate receptor; Neuroscience; Metabotropic receptor; Glutamatergic; Allosteric regulation; Neuroprotection; Glutamate receptor; Allosteric modulator; Pharmacology; Schizophrenia (object-oriented programming); Metabotropic glutamate receptor 2; Metabotropic glutamate receptor 5; Receptor; Biology; Medicine; Internal medicine; Psychiatry","retraction":null,"screen_n_in":null,"score":{"opus":0.1821143139856324,"gpt":0.4463537400651789,"spread":0.2642394260795465,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004461325,0.0005362688,0.001578432,0.0003941066,0.0004322676,0.0001141954,0.001664327,0.0002304597,0.00003478792],"category_scores_gemma":[0.003392503,0.000439423,0.0007936593,0.0004141273,0.0004640652,0.000153655,0.0003839159,0.0004486371,0.00006314398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000523515,"about_ca_system_score_gemma":0.0003891894,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002662141,"about_ca_topic_score_gemma":1.506745e-7,"domain_scores_codex":[0.9962875,0.0005570741,0.0006835097,0.001206325,0.0005101089,0.0007555219],"domain_scores_gemma":[0.9974129,0.000749252,0.0007847607,0.0008160381,0.00005830292,0.0001787765],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000335669,0.0001584737,3.373297e-7,0.00196994,0.00004415875,0.0001256741,0.000006681682,0.000002282585,0.7297828,0.0002546073,0.0004072012,0.2672143],"study_design_scores_gemma":[0.0009843271,0.0002703504,4.467094e-7,0.0007741976,0.0003568073,0.00004295419,6.844873e-7,0.00004521144,0.173832,0.00004306918,0.8232744,0.0003755573],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002365397,0.9906934,0.0006511002,0.0001717818,0.001917257,0.003514102,0.0004244849,0.00008950292,0.0001729722],"genre_scores_gemma":[0.0002001895,0.9965075,0.0004258317,0.0003017243,0.0001155553,0.0004748317,0.00001397835,0.0001408228,0.001819573],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8228672,"threshold_uncertainty_score":0.9998057,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2168233751","doi":"10.1186/1756-6606-4-26","title":"Dopamine D1-D2 receptor heteromer signaling pathway in the brain: emerging physiological relevance","year":2011,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":120,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; National Institutes of Health; University of Toronto; Centre for Addiction and Mental Health","keywords":"Dopamine receptor D2; Neuroscience; Dopaminergic; Dopamine; Dopamine receptor; D2-like receptor; Dopamine receptor D3; Neurotransmitter receptor; Receptor; Striatum; Addiction; Signal transduction; D1-like receptor; Biology; Cell biology; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.05471948899145194,"gpt":0.2808950969351521,"spread":0.2261756079437001,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005542962,0.0003547969,0.0002939988,0.0001436751,0.0001517138,0.00007706949,0.001096482,0.0001162586,0.0004847587],"category_scores_gemma":[0.0009194827,0.0002690227,0.0001880293,0.0007178672,0.0002648183,0.0002660819,0.0001125567,0.0006123176,0.000299491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003977807,"about_ca_system_score_gemma":0.00002536626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001979163,"about_ca_topic_score_gemma":0.000002983855,"domain_scores_codex":[0.9963231,0.001015931,0.0004709447,0.0009229151,0.0005669779,0.0007001006],"domain_scores_gemma":[0.9986404,0.0003755209,0.0001380622,0.0007112439,0.00002725661,0.0001075104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002976712,0.000175663,0.0002368756,0.00001140474,0.00000193473,0.0004552607,0.001157702,0.00002752059,0.9940159,0.00049598,0.0003036651,0.003088361],"study_design_scores_gemma":[0.0004696495,0.0001873776,0.001028246,0.00004470927,0.000003741455,0.00004504521,0.00009739798,0.00002911302,0.9939316,0.0004222196,0.00338986,0.0003510775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949479,0.00004886757,0.000744202,0.002794247,0.0002331627,0.0006105018,0.00001224036,0.0001338837,0.000475018],"genre_scores_gemma":[0.9820221,0.000005529053,0.0006167784,0.01695751,0.00005286419,0.0001745935,0.000003822351,0.00005689069,0.0001099191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01416326,"threshold_uncertainty_score":0.9999762,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2147491548","doi":"10.1186/1756-6606-5-30","title":"Mercury-induced toxicity of rat cortical neurons is mediated through N-methyl-D-Aspartate receptors","year":2012,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Mercury impact and mitigation studies","field":"Environmental Science","cited_by":110,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Glutamate receptor; Excitotoxicity; NMDA receptor; Neuroscience; Neurotoxin; Neurotoxicity; Chemistry; Depolarization; Receptor; Biology; Biophysics; Toxicity; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.02581928953551002,"gpt":0.2872686076625188,"spread":0.2614493181270088,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003652257,0.0001818833,0.0002451152,0.00002420987,0.0001088405,0.00001024613,0.0001594377,0.00008260843,0.002256957],"category_scores_gemma":[0.0006047544,0.0001614616,0.0001035577,0.0003350474,0.0002257469,0.000227069,0.000150468,0.0001623897,0.000561906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004588203,"about_ca_system_score_gemma":0.00001084811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001022053,"about_ca_topic_score_gemma":0.00001386,"domain_scores_codex":[0.9983616,0.0002513831,0.000301007,0.0002291385,0.0004117952,0.0004450452],"domain_scores_gemma":[0.9992144,0.0001830986,0.0001088063,0.0002768767,0.00001368033,0.00020316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008900241,0.00009175868,0.008785784,0.000004855813,0.00002691306,0.000003365638,0.002575748,0.000007356444,0.9695856,0.0001589041,0.01789218,0.0008586574],"study_design_scores_gemma":[0.0003114999,0.00008168207,0.01548745,0.000007100301,0.0000315686,0.000004190762,0.0002326905,0.00004559728,0.9705768,0.0001515362,0.01285606,0.0002138922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913119,0.00008561021,0.0007618253,0.002497425,0.0003621168,0.0002029112,0.000009978719,0.00003854214,0.004729704],"genre_scores_gemma":[0.9951454,0.00001940871,0.0005575079,0.003903613,0.0000237474,0.00001367218,0.00001152991,0.00002013407,0.0003050035],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006701665,"threshold_uncertainty_score":0.9986551,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2891335670","doi":"10.1186/s13041-018-0392-5","title":"Novel and de novo mutations in pediatric refractory epilepsy","year":2018,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Key Research and Development Program of China; Shandong University","keywords":"Dravet syndrome; TSC1; Epilepsy; Tuberous sclerosis; Genetics; Medical genetics; Sanger sequencing; Rett syndrome; Intellectual disability; Medicine; Biology; Mutation; Bioinformatics; Gene; Pathology; Psychiatry","retraction":null,"screen_n_in":null,"score":{"opus":0.00683498750513487,"gpt":0.2382320780702956,"spread":0.2313970905651607,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001119052,0.0001048548,0.0000675983,0.00007173415,0.00004547459,0.00001594771,0.00009293427,0.00008560163,0.000009615311],"category_scores_gemma":[0.0001058133,0.0001192159,0.00002656277,0.0001231181,0.00007461353,0.000001857744,0.0000837492,0.00006030025,0.000008153783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000092417,"about_ca_system_score_gemma":0.00007198523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001267377,"about_ca_topic_score_gemma":0.00009091313,"domain_scores_codex":[0.9992831,0.00003268409,0.0001250671,0.0002771034,0.00007098196,0.000211013],"domain_scores_gemma":[0.99971,0.000008342156,0.00002923527,0.0001563678,0.00002805331,0.00006797114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00001037637,0.00005813057,0.01092767,0.000006967561,0.00000572099,0.000008629557,0.00008448119,0.00001458343,0.9875586,0.00005479413,0.0003052742,0.0009647621],"study_design_scores_gemma":[0.001634008,0.0004134716,0.6249948,0.000008235247,0.00001617044,0.00007410656,0.00008940182,0.000121149,0.3637024,0.0004217948,0.008089249,0.0004351514],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930775,0.0003275105,0.0048797,0.000377557,0.00004954551,0.0001040833,0.000006969502,0.000006244192,0.001170947],"genre_scores_gemma":[0.9946602,0.00009197646,0.003462688,0.001527441,0.0000340749,0.00001452537,0.00003758977,0.0000214729,0.0001500099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6238561,"threshold_uncertainty_score":0.4861483,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2144098186","doi":"10.1186/1756-6606-5-25","title":"Alzheimer’s disease Aβ assemblies mediating rapid disruption of synaptic plasticity and memory","year":2012,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":97,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Trinity College","funders":"Science Foundation Ireland; European Commission; Health Research Board","keywords":"Neuroscience; Synaptic plasticity; Neurodegeneration; Dementia; Long-term potentiation; Protein aggregation; Metaplasticity; Amyloid (mycology); Psychology; Disease; Chemistry; Biology; Medicine; Cell biology; Biochemistry; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.0667675837392589,"gpt":0.365229307335339,"spread":0.2984617235960801,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003125249,0.0004910838,0.00143292,0.0003049339,0.00008092767,0.00002640378,0.0001266632,0.0002107063,0.00009537477],"category_scores_gemma":[0.0005983151,0.0003837332,0.000498889,0.0002508397,0.0002170997,0.00009356602,0.0001709195,0.0003298433,0.00005558852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007398543,"about_ca_system_score_gemma":0.0005195956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001582136,"about_ca_topic_score_gemma":9.448553e-7,"domain_scores_codex":[0.9973618,0.0004103406,0.0005447129,0.0004853379,0.0006749029,0.0005228519],"domain_scores_gemma":[0.9976943,0.0004820909,0.0003170893,0.0004346853,0.0000879096,0.0009839365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0001099136,0.0006395304,0.0002482297,0.01994853,0.02299098,0.001042574,0.00005656579,5.394576e-7,0.00005786345,0.0001498837,0.0001223596,0.9546331],"study_design_scores_gemma":[0.02130152,0.004548461,0.01571655,0.1288207,0.6425064,0.00175937,0.0005125889,0.001519544,0.001896401,0.0008901328,0.1717742,0.008754056],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001926556,0.9959186,0.0001029364,0.0000949812,0.00006389429,0.00140728,0.0002103578,0.00004763226,0.0002277052],"genre_scores_gemma":[0.05079174,0.9475893,0.0001945445,0.00006670028,0.000153357,0.0002210173,0.0008665502,0.0001053478,0.000011482],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.945879,"threshold_uncertainty_score":0.9998615,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2594459623","doi":"10.1186/s13041-017-0289-8","title":"Molecules in pain and sex: a developing story","year":2017,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; St. Michael's Hospital; Hospital for Sick Children; University of Toronto","funders":"Medical Research Council; Canadian Institutes of Health Research; Fondation Brain Canada","keywords":"Microglia; Neuropathic pain; Neuroscience; Disinhibition; Chronic pain; Medicine; Nociception; Spinal cord; Psychology; Inflammation; Immunology; Internal medicine; Receptor","retraction":null,"screen_n_in":null,"score":{"opus":0.06940482021035363,"gpt":0.3651876145583559,"spread":0.2957827943480023,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00120591,0.0003899175,0.001369387,0.0002773094,0.00008432595,0.00003807574,0.0001398894,0.0003049553,0.000009682865],"category_scores_gemma":[0.00059013,0.0003293535,0.0002216522,0.00008969924,0.00004902693,0.00002418966,0.0001024415,0.0003637978,0.0000172701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001849814,"about_ca_system_score_gemma":0.0003929485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000023682,"about_ca_topic_score_gemma":0.00001169184,"domain_scores_codex":[0.9981307,0.0005870092,0.0002898624,0.0004922916,0.0001926259,0.0003075128],"domain_scores_gemma":[0.9990017,0.0001512191,0.0001776663,0.0005321192,0.00001483963,0.0001224687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000157364,0.00003075852,0.00001752582,0.005329888,0.0001743016,0.002975512,0.00003923668,3.46925e-8,0.00001498307,0.0004483211,0.0001279995,0.9908398],"study_design_scores_gemma":[0.0006351193,0.00009210817,0.00003088198,0.01454672,0.0002822648,0.0001647343,0.00001249978,0.00001137444,0.00001935815,0.0002900437,0.983584,0.0003308957],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007222677,0.9947686,0.00325711,0.0002966828,0.00004228997,0.0008716455,0.000008311324,0.00003155761,0.0006516298],"genre_scores_gemma":[0.00005318367,0.9914758,0.006152893,0.000961169,0.00003327164,0.0001657813,0.0001157135,0.00008683724,0.0009553888],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.990509,"threshold_uncertainty_score":0.9999158,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2113812139","doi":"10.1186/1756-6606-3-25","title":"Schizophrenia, amphetamine-induced sensitized state and acute amphetamine exposure all show a common alteration: increased dopamine D2 receptor dimerization","year":2010,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":88,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Amphetamine; Striatum; Dopamine; Dopamine receptor D2; Neuroscience; Psychosis; Receptor; Pharmacology; Schizophrenia (object-oriented programming); Chemistry; Biology; Internal medicine; Psychology; Medicine; Psychiatry","retraction":null,"screen_n_in":null,"score":{"opus":0.01360984630870901,"gpt":0.2638453725475866,"spread":0.2502355262388776,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003308177,0.0005573839,0.0005118223,0.000252409,0.0002356398,0.0003888333,0.0004138462,0.0001960494,0.000218159],"category_scores_gemma":[0.0003893405,0.00057154,0.0001400943,0.0005490219,0.0002569195,0.0005387387,0.0001414322,0.0006614713,0.000129843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003414823,"about_ca_system_score_gemma":0.00007112936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005510748,"about_ca_topic_score_gemma":0.00006434871,"domain_scores_codex":[0.9963212,0.0006313109,0.0006256934,0.001122546,0.0006822585,0.0006169638],"domain_scores_gemma":[0.9981408,0.000225228,0.0002613605,0.0008684162,0.0001053993,0.0003988421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001992561,0.0001383857,0.0006963675,0.00001850777,0.00002092943,0.0003858061,0.0002318195,0.000008991477,0.9896532,0.000138164,0.00009648296,0.008412074],"study_design_scores_gemma":[0.003028474,0.0002883563,0.002788838,0.00002654504,0.00007004228,0.0002834197,0.00000888315,0.0006370096,0.991435,0.00006782312,0.0007710411,0.0005945489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938167,0.00001394346,0.001552591,0.002502049,0.0005252874,0.001141959,0.0001280965,0.0002566937,0.00006270005],"genre_scores_gemma":[0.9922533,0.0000134308,0.001963879,0.005018352,0.00009825418,0.0001297694,0.0001434182,0.0001231561,0.0002564189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007817525,"threshold_uncertainty_score":0.9996736,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2148097152","doi":"10.1186/1756-6606-4-6","title":"Neurabin in the anterior cingulate cortex regulates anxiety-like behavior in adult mice","year":2011,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":88,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; Ministry of Education, Science and Technology; Korea Science and Engineering Foundation","keywords":"Anxiety; Anterior cingulate cortex; Psychopharmacology; Prefrontal cortex; Neuroscience; Psychology; Glutamate receptor; Depression (economics); Cingulate cortex; Psychiatry; Internal medicine; Medicine; Cognition; Central nervous system; Receptor","retraction":null,"screen_n_in":null,"score":{"opus":0.03345966891449199,"gpt":0.3097156127666123,"spread":0.2762559438521203,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005680628,0.000231867,0.0002184033,0.0003348449,0.000133415,0.00007144434,0.001143143,0.00008820616,0.00006938513],"category_scores_gemma":[0.0005452062,0.0001867137,0.00009668765,0.001239855,0.0004140197,0.0002097278,0.0002040031,0.0006082112,0.00007149512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002605671,"about_ca_system_score_gemma":0.00005556884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000110838,"about_ca_topic_score_gemma":0.000064559,"domain_scores_codex":[0.9965543,0.001044734,0.0003657182,0.0008319857,0.0004640553,0.0007391837],"domain_scores_gemma":[0.9990866,0.0002062501,0.00008176964,0.0004971806,0.0000300201,0.00009818131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007569529,0.000279397,0.00515488,0.000007774668,5.662583e-7,0.004317064,0.0007725517,0.000003108293,0.9883221,0.0001361,0.0001261624,0.0008046189],"study_design_scores_gemma":[0.0007256954,0.0001900964,0.09902599,0.0000167969,0.000005816539,0.0003221297,0.0000608033,0.0003992217,0.8988298,0.0001112977,0.0001198093,0.0001925917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970409,0.00002699968,0.000007407759,0.001259767,0.0002650381,0.0007559129,0.000005996324,0.00004624661,0.0005917326],"genre_scores_gemma":[0.9826856,0.00006087749,0.00002157886,0.01680495,0.00001413561,0.0001399179,4.764588e-7,0.00003331206,0.0002391135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09387112,"threshold_uncertainty_score":0.7613963,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1973320429","doi":"10.1186/s13041-015-0117-y","title":"Characterization of Aldh2 -/- mice as an age-related model of cognitive impairment and Alzheimer’s disease","year":2015,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Queen's University","funders":"University of Occupational and Environmental Health","keywords":"ALDH2; Oxidative stress; Morris water navigation task; Endocrinology; Internal medicine; Atrophy; Lipid peroxidation; Presenilin; Psychology; Neuroscience; Amyloid beta; Hippocampal formation; Alzheimer's disease; Medicine; Chemistry; Disease; Aldehyde dehydrogenase; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.03241799620181508,"gpt":0.3177022928389723,"spread":0.2852842966371573,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001358061,0.0001310854,0.0002239908,0.0001008747,0.0000202704,0.000007539529,0.00004424339,0.00005038312,0.00002113197],"category_scores_gemma":[0.0001196704,0.0001182697,0.00006522739,0.0001190191,0.0001434185,0.00009224417,0.000045131,0.00006034269,0.000008619264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002020095,"about_ca_system_score_gemma":0.0003171826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005461022,"about_ca_topic_score_gemma":0.000001215347,"domain_scores_codex":[0.9989108,0.0001076223,0.0002066415,0.0002287669,0.0003694667,0.0001766879],"domain_scores_gemma":[0.9988325,0.00002160474,0.00009104298,0.0001835344,0.0002049345,0.0006663894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009722767,0.009276315,0.02292318,0.0003536603,0.02065142,0.003658531,0.005087195,0.0001508896,0.9184802,0.002097927,0.0001754965,0.00742247],"study_design_scores_gemma":[0.03611003,0.007240141,0.1849697,0.001323891,0.009943131,0.00008637007,0.0009423816,0.07246029,0.6774424,0.008526993,0.00001569081,0.0009390084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996654,0.001424372,0.0002878045,0.0004566118,0.000009565579,0.0007144866,0.0001922844,0.00001882706,0.000242008],"genre_scores_gemma":[0.9983239,0.00002369742,0.0001223935,0.0002651442,0.000006720642,0.00003034676,0.001173011,0.00002436406,0.00003040406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2410378,"threshold_uncertainty_score":0.4822899,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2103714201","doi":"10.1186/1756-6606-7-47","title":"Effects of NB001 and gabapentin on irritable bowel syndrome-induced behavioral anxiety and spontaneous pain","year":2014,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"China Scholarship Council; Canadian Institutes of Health Research; Azrieli Foundation; National Natural Science Foundation of China; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada","keywords":"Gabapentin; Irritable bowel syndrome; Anxiety; Elevated plus maze; Medicine; Open field; Abdominal pain; Anesthesia; Hyperalgesia; Psychology; Internal medicine; Psychiatry; Nociception","retraction":null,"screen_n_in":null,"score":{"opus":0.005020154964872765,"gpt":0.226312905560192,"spread":0.2212927505953192,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000475303,0.0001575832,0.0002768442,0.00007226363,0.00004073151,0.00001426835,0.00004551317,0.00007148161,0.00001278915],"category_scores_gemma":[0.0007852312,0.0001523822,0.00006047515,0.00007748364,0.00007608296,0.00002477569,0.00004056422,0.0001561809,0.000003937804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001390126,"about_ca_system_score_gemma":0.00001712138,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001332686,"about_ca_topic_score_gemma":0.00002011809,"domain_scores_codex":[0.9989324,0.0001985926,0.0001608468,0.0002865332,0.0001860712,0.0002355254],"domain_scores_gemma":[0.9993434,0.0002245428,0.00004865586,0.0001908358,0.00002970925,0.0001628521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003497888,0.0007838501,0.02183033,0.0009364662,0.00003711342,0.003540745,0.0002081678,0.000004049558,0.9498677,0.0003554558,0.000285186,0.02180116],"study_design_scores_gemma":[0.01507551,0.01731221,0.7868857,0.002354851,0.0005937049,0.02237747,0.0004212825,0.002984597,0.1488227,0.001687336,0.0005991639,0.0008854428],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973328,0.0001000785,0.001057068,0.0006379926,0.00002603728,0.0004036592,0.000002064531,0.00003126512,0.0004090336],"genre_scores_gemma":[0.9979787,0.000002537541,0.0009680212,0.0009024121,0.000006593971,0.00001004551,0.00001076501,0.00002094109,0.0001000253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8010449,"threshold_uncertainty_score":0.6213967,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3034916355","doi":"10.1186/s13041-020-00627-z","title":"Ketamine and its metabolite, (2R,6R)-HNK, restore hippocampal LTP and long-term spatial memory in the Wistar-Kyoto rat model of depression","year":2020,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Treatment of Major Depression","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia Hospital; University of British Columbia; Vancouver Coastal Health","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of British Columbia and Yukon; University of British Columbia; Heart and Stroke Foundation of Canada","keywords":"Long-term potentiation; Hippocampal formation; Synaptic plasticity; Neuroscience; Behavioural despair test; Antidepressant; Ketamine; NMDA receptor; Hippocampus; Psychology; Chemistry; Internal medicine; Medicine; Receptor","retraction":null,"screen_n_in":null,"score":{"opus":0.02223105735739344,"gpt":0.2669319294074277,"spread":0.2447008720500342,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002480281,0.0002401998,0.0004095042,0.00009425607,0.00004567968,0.00002071609,0.00013631,0.0001245347,0.00001450685],"category_scores_gemma":[0.0003266918,0.0001667007,0.00007084579,0.0001543147,0.00008656651,0.00008647452,0.0001541502,0.0002328181,0.000002043707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001948802,"about_ca_system_score_gemma":0.00006083168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003006933,"about_ca_topic_score_gemma":0.00002626384,"domain_scores_codex":[0.9983528,0.0002222187,0.0002972042,0.0004500443,0.0004489792,0.0002287788],"domain_scores_gemma":[0.9992167,0.00009428654,0.0001029527,0.0003574368,0.00004371804,0.0001848836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006845442,0.000211067,0.05728459,0.0002942826,0.00005934282,0.000679487,0.00162415,0.0001657303,0.9291883,0.00006759992,0.0002651649,0.009475739],"study_design_scores_gemma":[0.01214735,0.0006751007,0.5764024,0.0005170773,0.000507372,0.0001479547,0.0001517134,0.02417516,0.3844823,0.0002007456,0.0001384511,0.000454421],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872522,0.006192476,0.001377792,0.00402016,0.00003269398,0.0008193621,0.00001876405,0.00003077104,0.0002558005],"genre_scores_gemma":[0.9973878,0.00008363759,0.0005513307,0.001682218,0.00005555985,0.00003431303,0.00006403067,0.00003612028,0.000104964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.544706,"threshold_uncertainty_score":0.6797857,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2479769265","doi":"10.1186/s13041-016-0256-9","title":"Astrocyte-secreted thrombospondin-1 modulates synapse and spine defects in the fragile X mouse model","year":2016,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University","funders":"McMaster University; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada","keywords":"Astrocyte; Fragile X syndrome; Dendritic spine; Synaptogenesis; FMR1; Neuroscience; Neuroligin; Synapse; Biology; Thrombospondin; Thrombospondins; Cell biology; Knockout mouse; Scaffold protein; Excitatory postsynaptic potential; Signal transduction; Hippocampal formation; Fragile x; Central nervous system; Genetics; Inhibitory postsynaptic potential; Receptor","retraction":null,"screen_n_in":null,"score":{"opus":0.00656058563102102,"gpt":0.2188985734855178,"spread":0.2123379878544968,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001588444,0.0001923695,0.0001512633,0.0000581237,0.00005297622,0.00002514441,0.0002016208,0.0001030767,0.000005245436],"category_scores_gemma":[0.00008979801,0.0001248423,0.00006845822,0.00009730372,0.0000872189,0.000003847739,0.0001387997,0.00006308676,0.000005548285],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000864264,"about_ca_system_score_gemma":0.00003392544,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003830043,"about_ca_topic_score_gemma":0.00001740201,"domain_scores_codex":[0.9989419,0.00009411805,0.0001718869,0.0003887786,0.000122508,0.0002808014],"domain_scores_gemma":[0.999545,0.00001498684,0.00004241559,0.0003205708,0.00001706974,0.0000599731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001227481,0.00003326683,0.0002718167,0.00001282721,0.00001686382,0.000008034292,0.00005196853,0.0001813366,0.9971409,0.0002461864,0.0000968616,0.001927659],"study_design_scores_gemma":[0.001560362,0.0002988376,0.008400551,0.00004895101,0.00002037495,0.00002524916,0.0000651325,0.0007420052,0.985161,0.0007037529,0.002498613,0.0004751484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886525,0.004488968,0.006020245,0.0004402941,0.00001326389,0.0002505417,0.00001299633,0.00001012469,0.0001110268],"genre_scores_gemma":[0.9961201,0.002046851,0.000617367,0.0009631327,0.000004946698,0.00003878124,0.00002842877,0.00003132643,0.0001490564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01197988,"threshold_uncertainty_score":0.5090922,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2015822507","doi":"10.1186/s13041-014-0076-8","title":"Postsynaptic insertion of AMPA receptor onto cortical pyramidal neurons in the anterior cingulate cortex after peripheral nerve injury","year":2014,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"National Institute for Physiological Sciences; Canadian Institutes of Health Research; National Institute of Neurological Disorders and Stroke; Kitasato University; Fourth Military Medical University; National Natural Science Foundation of China; King's College London; University of Toronto; Johns Hopkins University; Howard Hughes Medical Institute","keywords":"Postsynaptic potential; AMPA receptor; Neuroscience; Long-term potentiation; Peripheral nerve injury; Nerve injury; Excitatory postsynaptic potential; Anterior cingulate cortex; Inhibitory postsynaptic potential; Medicine; Glutamate receptor; Anesthesia; Biology; Receptor; Internal medicine; Sciatic nerve","retraction":null,"screen_n_in":null,"score":{"opus":0.005094896745128546,"gpt":0.2483357014813984,"spread":0.2432408047362698,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000385827,0.0001674328,0.000294504,0.00008075453,0.00003385885,0.00001791236,0.00009064151,0.00009133778,0.00009364704],"category_scores_gemma":[0.000246121,0.0001210034,0.0001333533,0.0001489888,0.00007885396,0.00003855347,0.00003591845,0.0001960578,0.00001711117],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005551304,"about_ca_system_score_gemma":0.00003554612,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001307951,"about_ca_topic_score_gemma":0.0000514057,"domain_scores_codex":[0.9985546,0.0003492028,0.0003120819,0.0002568145,0.0002653797,0.0002619169],"domain_scores_gemma":[0.9993832,0.00005710288,0.00006966418,0.0003664872,0.00003868086,0.00008491096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005646287,0.0003451236,0.01356655,0.00003737783,0.00004793125,0.0002504292,0.0005504891,0.000003689659,0.9814544,0.0004340578,0.0000400684,0.002705309],"study_design_scores_gemma":[0.002450355,0.00195124,0.9661409,0.0002185839,0.0001088305,0.00007928052,0.0001221303,0.00384411,0.02431514,0.0003584633,0.0002102619,0.0002007351],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962041,0.00007527035,0.001503337,0.001569225,0.00009190141,0.000405369,0.000007062528,0.00002263772,0.0001210861],"genre_scores_gemma":[0.9956723,0.000003231504,0.0005591506,0.003562212,0.00003252365,0.00004570413,0.00002186428,0.00002770414,0.00007534475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9571392,"threshold_uncertainty_score":0.4934374,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2365630593","doi":"10.1186/s13041-016-0232-4","title":"rAAV-compatible MiniPromoters for restricted expression in the brain and eye","year":2016,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Simon Fraser University; Child and Family Research Institute; University of British Columbia","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Department of Psychiatry, Faculty of Medicine, University of British Columbia; University of North Carolina at Chapel Hill; Child and Family Research Institute; BC Cancer Agency; Simon Fraser University; Genome Canada; National Institute of General Medical Sciences; Canada's Michael Smith Genome Sciences Centre; Genome British Columbia; Fondation Brain Canada; GlaxoSmithKline","keywords":"Biology; Genetic enhancement; Promoter; Gene expression; Gene delivery; Neuroscience; Gene; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.01493948295629108,"gpt":0.3049038852342251,"spread":0.289964402277934,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005809082,0.0001541141,0.0001235535,0.00008450617,0.00007070375,0.00003256483,0.0003186346,0.0001253271,0.00001088779],"category_scores_gemma":[0.0004349524,0.00009667486,0.00006948598,0.0001410436,0.000105486,0.000004631757,0.00008857703,0.00006960604,0.000003782069],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001502759,"about_ca_system_score_gemma":0.00006173537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007301873,"about_ca_topic_score_gemma":0.00005130767,"domain_scores_codex":[0.9985495,0.0003455964,0.0001738532,0.0004040561,0.0001831176,0.0003439394],"domain_scores_gemma":[0.9992308,0.0001282931,0.00004621296,0.0004856068,0.00004176651,0.00006730627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005847248,0.00004416051,0.0003364901,0.00001010338,0.00001371007,0.00001059564,0.00008147257,0.000004527275,0.9813464,0.00002682272,0.009267644,0.008273291],"study_design_scores_gemma":[0.002066753,0.001244064,0.001171907,0.00003367299,0.000003110913,0.000004909898,0.00004744608,0.00003736663,0.9771271,0.0003360691,0.01775879,0.0001687507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97692,0.0005189769,0.006223388,0.01551292,0.0000277577,0.0006332177,0.00002334577,0.000009566907,0.0001308212],"genre_scores_gemma":[0.9948862,0.00003837352,0.000733383,0.003387285,0.00006118609,0.0001638437,0.00005255778,0.00003623757,0.000640967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01796616,"threshold_uncertainty_score":0.3942286,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2101371013","doi":"10.1186/1756-6606-5-11","title":"Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons","year":2012,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":83,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Banting Research Foundation; University of Washington","keywords":"TRPM2; Glutathione; Transient receptor potential channel; Cell biology; Oxidative stress; Hippocampal formation; Chemistry; Intracellular; Patch clamp; Neuroscience; Biology; Biophysics; Biochemistry; Receptor","retraction":null,"screen_n_in":null,"score":{"opus":0.02094538085885514,"gpt":0.2461600232802983,"spread":0.2252146424214432,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002879605,0.0002457112,0.0002690111,0.0001740794,0.00009950973,0.00002547356,0.0002109826,0.0001272884,0.00002509355],"category_scores_gemma":[0.001138173,0.0002039129,0.00008868692,0.0008001194,0.0002375426,0.0002879082,0.0000659508,0.000267497,0.00001049951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006250373,"about_ca_system_score_gemma":0.00004837313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002989381,"about_ca_topic_score_gemma":0.00000548643,"domain_scores_codex":[0.9978467,0.0004028828,0.000293326,0.0003958129,0.0005093263,0.0005519556],"domain_scores_gemma":[0.9992375,0.0002234097,0.0001781171,0.0001598229,0.00006045367,0.0001407274],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007069488,0.0003543422,0.0007283204,0.00002078095,0.00000823541,0.00002197128,0.002019232,0.001059311,0.9949218,0.0002169771,0.00005491733,0.0005233873],"study_design_scores_gemma":[0.0008574229,0.0001618278,0.01057931,0.00006500427,0.000008348821,0.00001360812,0.0002616384,0.0008632062,0.9867368,0.0001348189,0.0000506607,0.0002673223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955666,0.00003692792,0.002313323,0.001357571,0.000222334,0.00031427,0.00005190306,0.00005993767,0.00007714668],"genre_scores_gemma":[0.9990399,0.000008950497,0.00006354594,0.0006722013,0.00003588232,0.00002358723,0.00002786177,0.00003306179,0.00009501405],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009850985,"threshold_uncertainty_score":0.8315326,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1992276619","doi":"10.1186/1756-6606-4-20","title":"GPCR oligomers in pharmacology and signaling","year":2011,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institutes of Health; National Institute of Mental Health; University of Toronto; Centre for Addiction and Mental Health","keywords":"G protein-coupled receptor; Heterotrimeric G protein; Internalization; Receptor; Signal transduction; Function (biology); G protein; Effector; Intracellular; Neuroscience; Computational biology; Cell biology; Biology; Chemistry; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.02269878161442701,"gpt":0.30789688824977,"spread":0.285198106635343,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004204763,0.000429839,0.0008247224,0.0001997758,0.00004232582,0.00002520527,0.0002812923,0.0005651301,0.0001447614],"category_scores_gemma":[0.00004715725,0.000414256,0.0002872947,0.0001644667,0.00006765208,0.000002449689,0.0002051127,0.0003003796,0.00001658268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002416702,"about_ca_system_score_gemma":0.0001356146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001438006,"about_ca_topic_score_gemma":0.000005442464,"domain_scores_codex":[0.9980206,0.000333041,0.0004469518,0.0006926653,0.00009164622,0.0004151062],"domain_scores_gemma":[0.9993755,0.00002729123,0.0001755309,0.0002694062,0.00002481492,0.0001274828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001696756,0.00006511434,0.00000392334,0.002676866,0.0003236986,0.0001729163,0.00007311525,0.00000894188,0.388939,0.0004042657,0.0009403033,0.6063749],"study_design_scores_gemma":[0.0003280552,0.0001146742,2.315977e-7,0.0007927102,0.0001610901,0.00006418157,0.00001431596,0.000003527409,0.03681469,0.00009225509,0.9611034,0.0005108144],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002349359,0.9953019,0.001132167,0.00001890942,0.0002431061,0.0004792552,0.00001202261,0.00001237722,0.0004508741],"genre_scores_gemma":[0.0005238854,0.9975344,0.0007153663,0.000443434,0.0001640978,0.0001091476,0.0001706039,0.0001005944,0.000238453],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9601632,"threshold_uncertainty_score":0.9998309,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4225287980","doi":"10.1186/s13041-022-00923-w","title":"Central and peripheral contributions of T-type calcium channels in pain","year":2022,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Hotchkiss Brain Institute, University of Calgary; University of Calgary","keywords":"Neuroscience; Chronic pain; T-type calcium channel; Voltage-dependent calcium channel; Medicine; Psychology; Calcium; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.03653586066384145,"gpt":0.339633528184242,"spread":0.3030976675204005,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006137249,0.000250648,0.001123168,0.0001512536,0.00003816225,0.000008127439,0.00007359366,0.0001677932,0.0002289626],"category_scores_gemma":[0.0004591932,0.0002191103,0.0002443829,0.0002870809,0.00003706801,0.00001257362,0.00006981444,0.0002895932,0.000001177657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002343473,"about_ca_system_score_gemma":0.0002691785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006488402,"about_ca_topic_score_gemma":0.000002153577,"domain_scores_codex":[0.9982358,0.0005903154,0.0003539796,0.0003005112,0.0001965421,0.0003229017],"domain_scores_gemma":[0.9993493,0.0001364743,0.0001155347,0.0002462814,0.00002314449,0.0001292568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005139748,0.0007184527,0.00006780631,0.01087714,0.0009251723,0.003503257,0.0002438026,0.00001847133,0.0003716834,0.004742849,0.0007802274,0.9776998],"study_design_scores_gemma":[0.00152125,0.0005101928,0.00001401882,0.003200512,0.0005755581,0.0001322532,0.00002900186,0.0002418381,0.00007071159,0.0002268572,0.9932075,0.0002703454],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002455254,0.9961599,0.001995236,0.0001849748,0.0001364364,0.00100481,0.000105427,0.00001651349,0.000151243],"genre_scores_gemma":[0.002249376,0.9955968,0.0002211906,0.0004582088,0.00004296418,0.0001452769,0.0008195057,0.00005414322,0.0004125042],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9924272,"threshold_uncertainty_score":0.893506,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3013825907","doi":"10.1186/s13041-020-00586-5","title":"Ascending noradrenergic excitation from the locus coeruleus to the anterior cingulate cortex","year":2020,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":77,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Japan Society for the Promotion of Science; Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Locus coeruleus; Neuroscience; Psychopharmacology; Anterior cingulate cortex; Psychology; Central nervous system; Psychiatry; Cognition","retraction":null,"screen_n_in":null,"score":{"opus":0.04270505159007684,"gpt":0.3231204986530449,"spread":0.2804154470629681,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002595206,0.0001645032,0.0001428272,0.00004552663,0.0004708971,0.0002073641,0.001058319,0.0000356848,0.0000840811],"category_scores_gemma":[0.00167661,0.0001041263,0.00008577209,0.0009062508,0.0002155983,0.00009998033,0.0003292315,0.0003413078,0.0003945958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001768552,"about_ca_system_score_gemma":0.00005352325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002956642,"about_ca_topic_score_gemma":0.000006331544,"domain_scores_codex":[0.99748,0.0007007665,0.0002032991,0.0006576974,0.0005224747,0.0004357783],"domain_scores_gemma":[0.9987206,0.0006345739,0.0000665914,0.0003577727,0.00002692138,0.0001935058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004718616,0.00001515003,0.00007209243,0.000002056491,0.000002834629,0.0004855964,0.0006033326,0.000243124,0.9942116,0.0001488076,0.002743103,0.001425146],"study_design_scores_gemma":[0.0003731668,0.0001519629,0.002514082,0.00000982349,0.00001017379,0.0000202376,0.00005128465,0.00426371,0.985324,0.0001177003,0.007017691,0.0001461391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9142421,0.00005656224,0.001905707,0.08276274,0.0003499149,0.0004452425,0.00002527318,0.00007115553,0.0001413148],"genre_scores_gemma":[0.8852637,0.00001629501,0.00001720463,0.1144098,0.0001319618,0.00002953891,9.753498e-7,0.00002584325,0.0001046632],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03164708,"threshold_uncertainty_score":0.5071862,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2157482215","doi":"10.1186/s13041-014-0054-1","title":"The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid","year":2014,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research","keywords":"Endosome; Amyloid precursor protein; Alpha secretase; Cell biology; Golgi apparatus; Lysosome; Amyloid precursor protein secretase; Intracellular; Green fluorescent protein; P3 peptide; Brefeldin A; Amyloid beta; Biology; Chemistry; Biochemistry; Alzheimer's disease; Endoplasmic reticulum; Peptide","retraction":null,"screen_n_in":null,"score":{"opus":0.01226174961193721,"gpt":0.2748565524693246,"spread":0.2625948028573874,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005102631,0.0003378516,0.0003409454,0.00004216721,0.0004921932,0.0001936014,0.0004456351,0.0001138005,0.0001550251],"category_scores_gemma":[0.0001790369,0.0001612551,0.0001934839,0.0003802226,0.000250559,0.00008027983,0.0000757874,0.0003259877,0.0002016245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004157698,"about_ca_system_score_gemma":0.0002198787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003760878,"about_ca_topic_score_gemma":0.0002691233,"domain_scores_codex":[0.997422,0.0003282435,0.0003082062,0.0005874052,0.0007919322,0.0005622274],"domain_scores_gemma":[0.998081,0.0002380752,0.00008923296,0.001008385,0.0001500436,0.000433282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.007797732,0.002611535,0.01301584,0.0009259987,0.0491082,0.0008653063,0.04111091,0.00001855468,0.3561423,0.002343883,0.3983864,0.1276733],"study_design_scores_gemma":[0.01382903,0.002718277,0.03421972,0.0009075817,0.003592128,0.00004393182,0.002663368,0.001008034,0.3954001,0.007833564,0.536434,0.001350268],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.724369,0.02133632,0.0006742332,0.2481017,0.00003116932,0.00412505,0.0001456186,0.00006632502,0.001150565],"genre_scores_gemma":[0.9842338,0.000114929,0.0002134454,0.0137332,0.0001129738,0.000776735,0.0000880931,0.00006131914,0.0006655299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2598647,"threshold_uncertainty_score":0.6575793,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2132797631","doi":"10.1186/1756-6606-3-11","title":"Rapid and Direct Transport of Cell Surface APP to the Lysosome defines a novel selective pathway","year":2010,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Lysosome; Endosome; Cell biology; Amyloid precursor protein; Endocytosis; Transfection; Cell; Cell culture; Biology; Chemistry; Intracellular; Biochemistry; Alzheimer's disease; Enzyme","retraction":null,"screen_n_in":null,"score":{"opus":0.01064030309627483,"gpt":0.2524098839804583,"spread":0.2417695808841835,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001872532,0.0001371993,0.0002154482,0.00005130844,0.00005408707,0.000007334712,0.00007824916,0.00005431965,0.00003037438],"category_scores_gemma":[0.00007322692,0.00009118739,0.00009293235,0.0002357631,0.00008172897,0.00002302596,0.00002442464,0.0001518011,0.00001517872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001024985,"about_ca_system_score_gemma":0.0001530695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001075411,"about_ca_topic_score_gemma":0.00004737882,"domain_scores_codex":[0.9990577,0.0000379433,0.0001257914,0.0002493496,0.0002848843,0.0002443985],"domain_scores_gemma":[0.9992607,0.00007784733,0.00003097063,0.0002889531,0.00009179215,0.0002497984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002131229,0.0004617017,0.008185446,0.00004848518,0.0009912637,0.0001396167,0.0003433168,0.000006339308,0.9882125,0.0001093035,0.0002274187,0.001061524],"study_design_scores_gemma":[0.002355071,0.000479446,0.06462309,0.00003089381,0.0002507993,0.00003400704,0.00005931415,0.00006699622,0.9303204,0.00005461416,0.001572438,0.0001529102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920165,0.001892905,0.0002610224,0.001928683,0.0000239776,0.0006552119,0.0000897202,0.00002575368,0.003106232],"genre_scores_gemma":[0.9980745,0.00001748853,0.001235817,0.0004512922,0.0000197557,0.00002867702,0.00002941559,0.0000245653,0.0001184693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05789204,"threshold_uncertainty_score":0.3718514,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2164558765","doi":"10.1186/1756-6606-4-44","title":"Dependence of NMDA/GSK-3β Mediated Metaplasticity on TRPM2 Channels at Hippocampal CA3-CA1 Synapses","year":2011,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":69,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Toronto Western Hospital; Western University","funders":"Robarts Research Institute; Canadian Institutes of Health Research","keywords":"TRPM2; Neuroscience; NMDA receptor; Synaptic plasticity; Long-term potentiation; Neurotransmission; Hippocampal formation; Transient receptor potential channel; Hippocampus; Metaplasticity; Biology; Chemistry; Cell biology; Receptor; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.0456075879039291,"gpt":0.2505257032921979,"spread":0.2049181153882688,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003033983,0.0002984857,0.0003666807,0.0001873595,0.0001500673,0.00001904084,0.0005036745,0.0001798755,0.0006264491],"category_scores_gemma":[0.001868179,0.0002477029,0.0001891006,0.0004194994,0.0002681691,0.00009351777,0.0001932186,0.0002300774,0.0002903911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005479141,"about_ca_system_score_gemma":0.00005327266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008334382,"about_ca_topic_score_gemma":0.00002177602,"domain_scores_codex":[0.9974963,0.0003645936,0.0003732611,0.000639447,0.0006174049,0.0005089602],"domain_scores_gemma":[0.9987492,0.0004415744,0.0002135219,0.0003214688,0.00006113615,0.0002131276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001088746,0.0001921291,0.00004910301,0.00002548385,0.00002031597,0.0001446443,0.000704131,0.0001908131,0.9962131,0.001489843,0.000545553,0.0003160149],"study_design_scores_gemma":[0.0004621993,0.0003330751,0.0001519085,0.00004199398,0.00001825563,0.00002454439,0.00004643059,0.0006995958,0.9971316,0.0005664531,0.0002484808,0.0002754572],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994325,0.00005311473,0.001819336,0.0002940215,0.0009709342,0.000314735,0.00005545612,0.00009742955,0.002069929],"genre_scores_gemma":[0.9980059,0.00001938067,0.0001247703,0.001250333,0.00005272849,0.00002739873,0.000008181386,0.00004301642,0.0004683186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003680829,"threshold_uncertainty_score":0.9999975,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2169763883","doi":"10.1186/s13041-015-0107-0","title":"Glutamate receptors function as scaffolds for the regulation of β-amyloid and cellular prion protein signaling complexes","year":2015,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Robarts Clinical Trials; University of Calgary; Western University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Glutamate receptor; Ionotropic effect; Metabotropic glutamate receptor 5; Neuroscience; Metabotropic glutamate receptor; Metabotropic glutamate receptor 8; Metabotropic glutamate receptor 1; Biology; Neurodegeneration; Cell biology; Glutamatergic; Metabotropic glutamate receptor 6; Metabotropic glutamate receptor 7; Receptor; Signal transduction; Chemistry; Biochemistry; Medicine; Disease; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.04737271488943582,"gpt":0.3386620584580872,"spread":0.2912893435686514,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006568713,0.0003080035,0.0008352152,0.0001604363,0.0001129697,0.00003405411,0.00009621039,0.0002019218,0.00004655338],"category_scores_gemma":[0.0001212192,0.0002017127,0.0003470515,0.0002337185,0.0001187235,0.00004597746,0.00006008173,0.0001089738,0.00001800827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001062558,"about_ca_system_score_gemma":0.000418562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002906686,"about_ca_topic_score_gemma":8.638721e-7,"domain_scores_codex":[0.9981672,0.0002674992,0.0004104074,0.0003743119,0.0005139266,0.0002666446],"domain_scores_gemma":[0.9987718,0.0001399496,0.0002905313,0.0003883744,0.0002073103,0.0002019708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004764925,0.0002469365,0.000007570874,0.01737997,0.009226672,0.0000339964,0.00006615764,0.000004192797,0.01501499,0.0009914013,0.0008503763,0.9557012],"study_design_scores_gemma":[0.003979447,0.002367195,0.00002635813,0.01842208,0.0132331,0.00007244745,0.00008668809,0.0002606079,0.02059926,0.0029332,0.9373348,0.0006848261],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00374009,0.9896551,0.0009866386,0.0001663115,0.00005086627,0.005250732,0.00004497343,0.00003254065,0.00007274938],"genre_scores_gemma":[0.03205042,0.9595603,0.00140417,0.000125558,0.0003565539,0.001951589,0.003642005,0.0002986857,0.0006107297],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9550164,"threshold_uncertainty_score":0.8225606,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2937095482","doi":"10.1186/s13041-019-0456-1","title":"Modulation of mTOR and CREB pathways following mGluR5 blockade contribute to improved Huntington’s pathology in zQ175 mice","year":2019,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":68,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; Alberta Innovates; Institute of Neurosciences, Mental Health and Addiction; Alexandria University; Huntington Society of Canada","keywords":"Huntingtin; PI3K/AKT/mTOR pathway; CREB; Autophagy; Biology; Neurodegeneration; Cell biology; Huntingtin Protein; Huntington's disease; Neuroscience; Cancer research; Signal transduction; Genetics; Transcription factor; Medicine; Apoptosis; Mutant; Internal medicine; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.009596880573705157,"gpt":0.2366029468395587,"spread":0.2270060662658535,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002309367,0.0001689217,0.0002645133,0.0001598103,0.00003602343,0.00002805038,0.0001777688,0.0000686061,0.00001018653],"category_scores_gemma":[0.001576707,0.0001841673,0.00007994926,0.0002758089,0.0000362512,0.00006002049,0.0001475808,0.00009629157,0.00001439228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002407081,"about_ca_system_score_gemma":0.00004342187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002062096,"about_ca_topic_score_gemma":0.00001206806,"domain_scores_codex":[0.9982612,0.0003312143,0.0002909951,0.0005972573,0.0002009303,0.0003184141],"domain_scores_gemma":[0.9992636,0.0001923836,0.00009956443,0.0003104571,0.00003423633,0.00009975945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002604802,0.00004644017,0.003911439,0.00001735684,0.000003072018,0.00004433511,0.0002402395,0.0008936759,0.9941058,0.0002164865,0.00001143341,0.0004836474],"study_design_scores_gemma":[0.0009769209,0.0001276018,0.02551426,0.00002078274,0.000008169145,0.000004355906,0.00002951717,0.004209122,0.9687011,0.0001998128,0.00003952923,0.0001688367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968832,0.00004714505,0.001401575,0.0006115605,0.0002056845,0.0007011306,0.00003916823,0.00002632674,0.00008422184],"genre_scores_gemma":[0.9973325,0.000001408464,0.000516547,0.001993804,0.00001343997,0.00003040493,0.000005613067,0.0000282165,0.0000781002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02540473,"threshold_uncertainty_score":0.7510125,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2144106732","doi":"10.1186/1756-6606-7-20","title":"Disruption of the nuclear p53-GAPDH complex protects against ischemia-induced neuronal damage","year":2014,"lang":"en","type":"article","venue":"Molecular Brain","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Heart and Stroke Foundation of Canada","keywords":"Glyceraldehyde 3-phosphate dehydrogenase; Excitotoxicity; Cell biology; Programmed cell death; Glutamate receptor; Biology; Apoptosis; Biochemistry; Dehydrogenase; Enzyme","retraction":null,"screen_n_in":null,"score":{"opus":0.01140709530763613,"gpt":0.2338279750179285,"spread":0.2224208797102924,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001783226,0.0001646425,0.0001405024,0.00002840785,0.0000803994,0.00002319309,0.0003971831,0.0001342511,0.00002649744],"category_scores_gemma":[0.0001969732,0.0001345532,0.0001705084,0.00009236804,0.00008986899,0.000004210322,0.0002303371,0.0001361413,0.00002374431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008393562,"about_ca_system_score_gemma":0.00003329131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001171362,"about_ca_topic_score_gemma":0.000008692663,"domain_scores_codex":[0.9988957,0.0001778492,0.0002012792,0.0003214363,0.0001885612,0.0002151401],"domain_scores_gemma":[0.9991546,0.000009620067,0.0001164328,0.0005880219,0.00007383759,0.00005749388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000281461,0.00004076294,0.0001274999,0.00001770184,0.0000260838,0.000001801381,0.00002964904,0.00007884712,0.9952092,0.0001701953,0.002264183,0.002005948],"study_design_scores_gemma":[0.0003735207,0.0002182864,0.004427854,0.00002331705,0.000008224252,0.000004855167,0.00002290248,0.0007949987,0.9845496,0.00005932454,0.009350732,0.0001664167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944931,0.00002001183,0.001144135,0.0007615323,0.00008738306,0.0002430607,0.0000106731,0.00001250035,0.003227578],"genre_scores_gemma":[0.9965926,0.000003758929,0.0001922259,0.00280916,0.00008775765,0.0000121595,0.00005860151,0.00003152758,0.0002122459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01065961,"threshold_uncertainty_score":0.548692,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2155640973","doi":"10.1186/1756-6606-3-3","title":"DREAM (Downstream Regulatory Element Antagonist Modulator) contributes to synaptic depression and contextual fear memory","year":2010,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":64,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Consejo Superior de Investigaciones Científicas; Canadian Institutes of Health Research; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas; Ministerio de Economía y Competitividad","keywords":"Psychopharmacology; Neuroscience; Psychology; Antagonist; Dream; Psychiatry; Medicine; Receptor; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.01283720546685836,"gpt":0.2976565241941343,"spread":0.2848193187272759,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005273255,0.0002639961,0.0002720512,0.0002475248,0.0004567612,0.000167066,0.0005516056,0.0001222873,0.00006846114],"category_scores_gemma":[0.001457591,0.0002444525,0.00007261355,0.0004186234,0.0006857702,0.0001552305,0.0004726461,0.0005681653,0.0000917277],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002889589,"about_ca_system_score_gemma":0.0001053999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001307063,"about_ca_topic_score_gemma":0.000009217173,"domain_scores_codex":[0.9970999,0.0003363569,0.0002860695,0.001028598,0.0005418864,0.0007071517],"domain_scores_gemma":[0.9985033,0.0003714062,0.00007172333,0.0005769783,0.00005749998,0.0004191176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007810224,0.0001180622,0.001013012,0.00000918427,0.00000696874,0.0004756104,0.00004592378,0.00001981101,0.9919065,0.00103337,0.00176318,0.003530255],"study_design_scores_gemma":[0.001016813,0.0001898846,0.00328521,0.00001236284,0.00001225151,0.0001312634,0.00002188668,0.0007417015,0.9919044,0.000178297,0.002271569,0.0002343276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994019,0.00005998036,0.0002675593,0.003809076,0.0005185328,0.0007956724,0.00002539209,0.0001136971,0.0003910623],"genre_scores_gemma":[0.9872125,0.0000114083,0.00005242519,0.01209041,0.00004829618,0.00007031026,0.000001365618,0.00003910065,0.0004741255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008281333,"threshold_uncertainty_score":0.9968484,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2106085507","doi":"10.1186/1756-6606-6-13","title":"Delay-dependent impairment of spatial working memory with inhibition of NR2B-containing NMDA receptors in hippocampal CA1 region of rats","year":2013,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":63,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Program for Changjiang Scholars and Innovative Research Team in University; Ministry of Education of the People's Republic of China; National Natural Science Foundation of China","keywords":"Hippocampal formation; Spatial memory; Working memory; Neuroscience; NMDA receptor; Ifenprodil; Hippocampus; Psychology; Task (project management); Medicine; Cognition; Receptor; Engineering; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.02692890996786558,"gpt":0.2804097019210211,"spread":0.2534807919531555,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004270985,0.0001607195,0.0002937926,0.0003553022,0.00005061624,0.00001454611,0.0002655757,0.00006941968,0.00004562958],"category_scores_gemma":[0.0002849565,0.0001445258,0.00006823181,0.0005902429,0.000387279,0.0001571923,0.000146027,0.0002766725,0.000004409536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004929212,"about_ca_system_score_gemma":0.000130003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003261045,"about_ca_topic_score_gemma":0.00003186831,"domain_scores_codex":[0.9974576,0.0006163698,0.0004551173,0.0004648323,0.0006232384,0.0003828198],"domain_scores_gemma":[0.9990371,0.0002402419,0.0002935763,0.000264237,0.00007408219,0.0000907256],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002466884,0.0001979529,0.004041474,0.00003748928,0.000003304008,0.0003064766,0.0004102659,0.0004678568,0.9913751,0.00003981218,0.00003310106,0.002840475],"study_design_scores_gemma":[0.001106699,0.001011092,0.001438098,0.0001207532,0.000005284573,0.00004094169,0.0001329885,0.0005509723,0.9953797,0.00009148744,0.000004309095,0.0001176868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979652,0.00001585346,0.0006173291,0.0003596685,0.0001305802,0.0007087165,0.000001862489,0.00001502141,0.0001858274],"genre_scores_gemma":[0.9993204,0.00001483499,0.00005465649,0.0004779669,0.00001365444,0.00005075131,7.571928e-7,0.00002269736,0.00004424792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004004583,"threshold_uncertainty_score":0.589359,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1944550035","doi":"10.1186/s13041-015-0162-6","title":"Ubiquilin-2 drives NF-κB activity and cytosolic TDP-43 aggregation in neuronal cells","year":2015,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec","funders":"Canadian Institutes of Health Research","keywords":"Cytosol; Psychopharmacology; Chemistry; Cell biology; Neuroscience; NF-κB; Biology; Biochemistry; Apoptosis; Pharmacology; Enzyme","retraction":null,"screen_n_in":null,"score":{"opus":0.02704508126173463,"gpt":0.2992719176710449,"spread":0.2722268364093103,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000349867,0.0001429094,0.0002234451,0.0001383725,0.00002746971,0.00003244539,0.00008911486,0.0001098906,0.00003454382],"category_scores_gemma":[0.0003021819,0.000129617,0.00004623962,0.0002400382,0.0001161865,0.0001026497,0.0001248985,0.0003035429,0.00004506522],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000107209,"about_ca_system_score_gemma":0.0001375175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002087788,"about_ca_topic_score_gemma":0.00004326954,"domain_scores_codex":[0.9985001,0.0002286688,0.0001572755,0.0003374561,0.0004534641,0.0003230214],"domain_scores_gemma":[0.9992844,0.00006166949,0.00004210039,0.0002625251,0.00006549918,0.0002838273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001352348,0.00009570456,0.003880226,0.00002697034,0.00001354509,0.0001986397,0.0002791274,0.00003865387,0.9848896,0.00006418573,0.0004347752,0.009943306],"study_design_scores_gemma":[0.003682951,0.00053941,0.2995654,0.0001152669,0.0000169681,0.00004726596,0.00003535304,0.005161637,0.6887833,0.0006246606,0.001179148,0.0002486085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904333,0.0001437651,0.0003975597,0.007936784,0.00004421197,0.0003717814,0.000003444927,0.00003375355,0.0006353966],"genre_scores_gemma":[0.9979399,0.00002458117,0.0004529184,0.001046237,0.00006073884,0.0000188913,0.00001006897,0.0000278559,0.0004187665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2961063,"threshold_uncertainty_score":0.528563,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2768560702","doi":"10.1186/s13041-017-0332-9","title":"Tanshinone I alleviates motor and cognitive impairments via suppressing oxidative stress in the neonatal rats after hypoxic-ischemic brain damage","year":2017,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Neonatal and fetal brain pathology","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Chongqing Medical University; Chongqing University; University of British Columbia; National Key Research and Development Program of China; Chongqing Science and Technology Commission; National Natural Science Foundation of China","keywords":"Neuroprotection; Oxidative stress; Brain damage; Nitric oxide synthase; Hypoxia (environmental); Pharmacology; Superoxide dismutase; Ischemia; Nitric oxide; Glutathione; Catalase; Medicine; Chemistry; Anesthesia; Endocrinology; Internal medicine; Biochemistry; Enzyme; Oxygen","retraction":null,"screen_n_in":null,"score":{"opus":0.008888638253593933,"gpt":0.2696605183500807,"spread":0.2607718800964868,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004535571,0.0003041903,0.0003684403,0.0001068033,0.0002154791,0.000126528,0.0003045826,0.0001615088,0.00005411606],"category_scores_gemma":[0.000787262,0.000228201,0.0001033914,0.00007614897,0.0005275502,0.0002526886,0.000312506,0.0004363944,0.00001940786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000247295,"about_ca_system_score_gemma":0.00004002742,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005190489,"about_ca_topic_score_gemma":0.00003950238,"domain_scores_codex":[0.9981927,0.0002662011,0.0002641463,0.0005305896,0.0003074475,0.0004389457],"domain_scores_gemma":[0.9987813,0.0003438088,0.0001466065,0.0005314717,0.00005742739,0.0001393521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006442281,0.0001984859,0.01221978,0.0001088815,0.0001064211,0.0106792,0.003795366,2.588883e-7,0.9568442,0.00002689264,0.0002501872,0.0151261],"study_design_scores_gemma":[0.006963657,0.0008228155,0.4238699,0.000737607,0.000163335,0.001258175,0.002047508,0.0004933216,0.5615171,0.000978603,0.0005066932,0.000641265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889196,0.001142816,0.001261906,0.006641076,0.00005947022,0.0008411494,0.0001619491,0.00002486663,0.0009472081],"genre_scores_gemma":[0.993585,0.000008670435,0.0004094045,0.005198477,0.00006715605,0.0001143066,0.0001390037,0.00003817987,0.000439814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4116501,"threshold_uncertainty_score":0.9305768,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2264280914","doi":"10.1186/s13041-016-0197-3","title":"Maternal sleep deprivation at different stages of pregnancy impairs the emotional and cognitive functions, and suppresses hippocampal long-term potentiation in the offspring rats","year":2016,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":61,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; University of British Columbia Hospital","funders":"National Key Research and Development Program of China; Natural Science Foundation of Chongqing; China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"Long-term potentiation; Hippocampal formation; Offspring; Sleep deprivation; Hippocampus; Psychology; Neuroscience; Pregnancy; Endocrinology; Excitatory postsynaptic potential; Internal medicine; Effects of sleep deprivation on cognitive performance; Medicine; Cognition; Biology; Inhibitory postsynaptic potential","retraction":null,"screen_n_in":null,"score":{"opus":0.01928571674711222,"gpt":0.2662734839842574,"spread":0.2469877672371452,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000171008,0.00009661842,0.00008240751,0.00007895842,0.0001478618,0.00005978221,0.0001268613,0.00003046469,0.00003306684],"category_scores_gemma":[0.0004580447,0.00004969296,0.00002760712,0.0001052316,0.0001775377,0.000126785,0.0001323049,0.00007574158,0.000002220513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001906874,"about_ca_system_score_gemma":0.000008322942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001110283,"about_ca_topic_score_gemma":0.00003026971,"domain_scores_codex":[0.998693,0.0004014648,0.0001484843,0.0002403894,0.00034898,0.0001676574],"domain_scores_gemma":[0.9991705,0.0005645047,0.00006692722,0.0001364497,0.00003228975,0.00002927745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004140754,0.00004141515,0.4483888,0.00002534068,0.000008684742,0.00002106162,0.0001631162,0.000003959799,0.5251969,0.000255602,0.000004370813,0.02584938],"study_design_scores_gemma":[0.000379206,0.00003060895,0.5853494,0.0001064168,0.000006876079,0.00001713174,0.00002922664,0.00005849744,0.4137552,0.0002269023,5.041402e-7,0.00003993809],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920686,0.0001933141,0.005856848,0.001421952,0.0000416427,0.0003554236,0.00002889401,0.000008827074,0.0000245107],"genre_scores_gemma":[0.9997228,0.00004010347,0.000002462342,0.00009899196,0.00001318459,0.00005001927,0.000005424704,0.000008716103,0.00005832915],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1369607,"threshold_uncertainty_score":0.202642,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2160069145","doi":"10.1186/s13041-014-0085-7","title":"Statin treatment affects cytokine release and phagocytic activity in primary cultured microglia through two separable mechanisms","year":2014,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":57,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Microglia; Psychopharmacology; Cytokine; Statin; Primary (astronomy); Immunology; Neuroinflammation; Medicine; Neuroscience; Chemistry; Psychology; Pharmacology; Inflammation; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.01485867738268854,"gpt":0.2629039318486452,"spread":0.2480452544659567,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002077837,0.0002906043,0.0002843504,0.000101362,0.0001450019,0.0001063041,0.0001333037,0.00006468331,0.00002726358],"category_scores_gemma":[0.0003045301,0.0002706321,0.00006666577,0.0002783983,0.00004944661,0.0002348684,0.00006383019,0.000145908,0.00004078389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001148622,"about_ca_system_score_gemma":0.00005252991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002473434,"about_ca_topic_score_gemma":0.00003153416,"domain_scores_codex":[0.9976498,0.0007777255,0.0002080943,0.0007182451,0.0002902923,0.0003557878],"domain_scores_gemma":[0.9991624,0.0002087953,0.0001214288,0.0003668657,0.00001633015,0.0001241292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005578436,0.0001449628,0.000003699863,0.00002052648,0.000002806859,0.0001721534,0.0001778364,0.0004442244,0.9813693,0.01555021,0.0001077551,0.001950785],"study_design_scores_gemma":[0.002666613,0.0003061193,0.0000630545,0.00001381053,0.00001080972,0.00004815414,0.000005127259,0.006980551,0.9846174,0.004119164,0.0009214646,0.0002477533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9513209,0.0000183574,0.04543732,0.001333834,0.0001193972,0.0006579951,0.00001954843,0.0001310215,0.000961596],"genre_scores_gemma":[0.9893226,0.00002760971,0.003378688,0.006251786,0.00002383855,0.00007636908,0.00001266406,0.00004418372,0.0008622407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04205863,"threshold_uncertainty_score":0.9999746,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2151299849","doi":"10.1186/1756-6606-7-42","title":"Inorganic polyphosphate regulates neuronal excitability through modulation of voltage-gated channels","year":2014,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Dalhousie University; Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Polyphosphate; Neuroscience; Psychopharmacology; Modulation (music); Chemistry; Psychology; Biology; Pharmacology; Biochemistry; Phosphate; Physics","retraction":null,"screen_n_in":null,"score":{"opus":0.01123226186744096,"gpt":0.2476375440358745,"spread":0.2364052821684335,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004413855,0.000289168,0.0005200558,0.0001082413,0.00009389827,0.00002567822,0.0001528359,0.0001778882,0.0002470527],"category_scores_gemma":[0.0005859395,0.0002844806,0.0002368964,0.0004717102,0.0001784039,0.0001703971,0.00007738046,0.0001549852,0.00002822075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005098448,"about_ca_system_score_gemma":0.00008204996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001910467,"about_ca_topic_score_gemma":0.000009311212,"domain_scores_codex":[0.997896,0.0001420469,0.0005862552,0.0005167225,0.0004660866,0.00039286],"domain_scores_gemma":[0.9986041,0.0001488477,0.0002304695,0.0006545787,0.0002090439,0.0001529117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001883974,0.0002792637,0.01858643,0.0002044195,0.000126368,0.0000160462,0.0008685311,0.0009048075,0.961322,0.008302748,0.0005560987,0.008644908],"study_design_scores_gemma":[0.00233901,0.0003954299,0.393012,0.00012731,0.0001022236,0.00003093687,0.00003660785,0.02083779,0.5692423,0.01180165,0.001714588,0.0003601249],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738235,0.0005136525,0.02201771,0.002210824,0.0002677695,0.0004845334,0.000009672646,0.000150143,0.0005221823],"genre_scores_gemma":[0.9966704,0.000008279887,0.0008062055,0.0015352,0.0001512169,0.000009572896,0.0001518792,0.0000640741,0.0006032158],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3920797,"threshold_uncertainty_score":0.9999607,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3014784124","doi":"10.1186/s13041-020-00567-8","title":"Donald O. Hebb and the Organization of Behavior: 17 years in the writing","year":2020,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Neural dynamics and brain function","field":"Neuroscience","cited_by":56,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Dalhousie University","funders":"","keywords":"Cognitive science; Phrase; Hebbian theory; TRACE (psycholinguistics); Connectionism; Kinship; Sequence (biology); Psychology; Computer science; Artificial intelligence; Sociology; Artificial neural network; Linguistics; Philosophy","retraction":null,"screen_n_in":null,"score":{"opus":0.02558325478095305,"gpt":0.2840270434243874,"spread":0.2584437886434344,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003836537,0.0001471642,0.0003887881,0.0000606696,0.00005385913,0.00006984353,0.0003253071,0.00008099705,0.000007875245],"category_scores_gemma":[0.0008303498,0.00008708329,0.0001083908,0.0007033552,0.0001211867,0.00003043406,0.0001145537,0.0003018051,0.000004764668],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001553721,"about_ca_system_score_gemma":0.00003974816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001077048,"about_ca_topic_score_gemma":0.000002891555,"domain_scores_codex":[0.998448,0.0006131242,0.0003013941,0.0002853986,0.0002368976,0.0001151993],"domain_scores_gemma":[0.9990535,0.0005056136,0.0001849721,0.0002228411,0.00001389376,0.00001914742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000569232,0.00005839048,0.0000188716,0.001422031,0.00001287769,0.0004307636,0.0004235205,0.000006583854,0.010218,0.02053566,0.0008247051,0.9660429],"study_design_scores_gemma":[0.001273814,0.0001052294,0.000306735,0.002472187,0.0005064688,0.0006298645,0.00009789255,0.0004000337,0.0007788538,0.000736587,0.9920394,0.0006529164],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009593329,0.9815884,0.0003352732,0.005265059,0.0001972435,0.002409048,0.00005919651,0.00004364206,0.0005088263],"genre_scores_gemma":[0.01700636,0.9780332,0.00002716302,0.004634658,0.00005901208,0.00007005741,0.000043291,0.00005993943,0.00006626202],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9912147,"threshold_uncertainty_score":0.3551153,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2101766473","doi":"10.1186/1756-6606-2-36","title":"Action potential evoked transmitter release in central synapses: insights from the developing calyx of Held","year":2009,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Neural dynamics and brain function","field":"Neuroscience","cited_by":56,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Neuroscience; Postsynaptic potential; Neurotransmission; Synapse; Context (archaeology); Biology; Synaptic plasticity; Receptor","retraction":null,"screen_n_in":null,"score":{"opus":0.03321785897913086,"gpt":0.2841554689588401,"spread":0.2509376099797092,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001100505,0.0003721509,0.0007499692,0.0001765612,0.00008919019,0.00005677513,0.0004443759,0.0002865201,0.00001810857],"category_scores_gemma":[0.000312508,0.0002616017,0.0004352917,0.0006144018,0.00007669644,0.00009772393,0.00005204352,0.0005713425,0.000012844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001401226,"about_ca_system_score_gemma":0.000191265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001321259,"about_ca_topic_score_gemma":0.00007134612,"domain_scores_codex":[0.9973283,0.0006554957,0.0006326943,0.0006557254,0.0003789908,0.0003488197],"domain_scores_gemma":[0.9988686,0.0003426592,0.0002967591,0.0004061912,0.00002083913,0.00006497136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004612872,0.0001213643,0.000001268745,0.001321672,0.0000499965,0.0006884389,0.0001590346,0.0001366804,0.09528216,0.001846541,0.0002889359,0.9000578],"study_design_scores_gemma":[0.002507586,0.0004094126,0.0006527154,0.02264841,0.001065065,0.000280383,0.00006791879,0.003989941,0.04426356,0.01138004,0.9097917,0.002943261],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07125295,0.9092568,0.01328776,0.002154712,0.001324073,0.002309136,0.0001306586,0.00009596866,0.0001879879],"genre_scores_gemma":[0.04335659,0.9518969,0.0001223703,0.004037476,0.0001745056,0.00005212607,0.0001506752,0.00007922958,0.0001301259],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9095027,"threshold_uncertainty_score":0.9999836,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2132532899","doi":"10.1186/1756-6606-4-29","title":"Fetal alcohol exposure leads to abnormal olfactory bulb development and impaired odor discrimination in adult mice","year":2011,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Prenatal Substance Exposure Effects","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression","keywords":"Olfactory bulb; Neurogenesis; Odor; Olfactory system; Fetus; Neuroscience; Offspring; Fetal alcohol syndrome; Biology; Internal medicine; Endocrinology; Central nervous system; Medicine; Pregnancy; Ethanol; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.0222865807530974,"gpt":0.2427880138697574,"spread":0.22050143311666,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003136637,0.0002195557,0.0002566429,0.0001990755,0.00004000153,0.00001398043,0.0001060358,0.0001225943,0.00002790466],"category_scores_gemma":[0.0003200337,0.000210279,0.00004838433,0.0002097561,0.00004421748,0.0001276318,0.00008327658,0.0001882413,0.00004046228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001391305,"about_ca_system_score_gemma":0.00008266694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006970272,"about_ca_topic_score_gemma":0.0002989383,"domain_scores_codex":[0.9985734,0.00009860712,0.000287716,0.0003781275,0.000306233,0.0003559705],"domain_scores_gemma":[0.9993786,0.00003757537,0.00005445059,0.0002348255,0.00006724821,0.0002272736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003969307,0.0002213897,0.04359449,0.0001822483,0.00004946137,0.001089007,0.01324318,0.00000275507,0.9099376,0.0002100442,0.0003162334,0.03075669],"study_design_scores_gemma":[0.001703473,0.000275763,0.457483,0.0001714702,0.00001772063,0.00005765201,0.0001775547,0.00003266613,0.5397584,0.00001526532,0.00009375659,0.000213272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956674,0.0002695169,0.001884703,0.0004892517,0.00009805673,0.0007092963,0.000003788161,0.00006580233,0.0008121655],"genre_scores_gemma":[0.9907614,0.000001821007,0.007451008,0.001409441,0.00002742415,0.00008628579,0.00004235646,0.00003697741,0.0001832723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4138885,"threshold_uncertainty_score":0.8574928,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2176291309","doi":"10.1186/s13041-015-0169-z","title":"Long-term upregulation of cortical glutamatergic AMPA receptors in a mouse model of chronic visceral pain","year":2015,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Canada Research Chairs","funders":"Azrieli Foundation; Canadian Institutes of Health Research; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada","keywords":"AMPA receptor; Neuroscience; Long-term potentiation; Visceral pain; Glutamatergic; Medicine; Glutamate receptor; Receptor; Chronic pain; Anterior cingulate cortex; Endocrinology; Internal medicine; Biology; Nociception","retraction":null,"screen_n_in":null,"score":{"opus":0.01999508291968383,"gpt":0.2761397462841946,"spread":0.2561446633645107,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000562356,0.0001245094,0.0002963839,0.000116285,0.000008863204,0.00000381613,0.00005891183,0.00009620301,0.00002491672],"category_scores_gemma":[0.000172541,0.0001124392,0.00008101442,0.0001216854,0.0000484851,0.00003520882,0.00003062159,0.00008283518,0.00000409456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001699691,"about_ca_system_score_gemma":0.0001377484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004618189,"about_ca_topic_score_gemma":0.00002369292,"domain_scores_codex":[0.9988438,0.0001906581,0.0003105796,0.0001853167,0.0002791966,0.0001903771],"domain_scores_gemma":[0.9994541,0.00002808862,0.00008679362,0.0002517973,0.00005741121,0.0001217971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002252274,0.0006118694,0.02471436,0.0001539822,0.00007546491,0.00007424581,0.0004279087,0.004001105,0.9656799,0.0008240826,0.00005296003,0.003158927],"study_design_scores_gemma":[0.006188294,0.00117533,0.01191081,0.0002833812,0.00007084686,0.00001031636,0.00004106551,0.2341585,0.744641,0.001333642,0.000003257363,0.0001835761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9519564,0.000116706,0.04729268,0.0001935354,0.00002645476,0.0003207426,0.000006432378,0.00001777835,0.00006929369],"genre_scores_gemma":[0.99741,0.00000355524,0.002020172,0.0001390641,0.00001167904,0.00001697183,0.00005750398,0.00002345099,0.000317604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2301574,"threshold_uncertainty_score":0.4585136,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2129224838","doi":"10.1186/1756-6606-1-9","title":"Induction- and conditioning-protocol dependent involvement of NR2B-containing NMDA receptors in synaptic potentiation and contextual fear memory in the hippocampal CA1 region of rats","year":2008,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":53,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Program for Changjiang Scholars and Innovative Research Team in University; Canadian Institutes of Health Research; Ministry of Education of the People's Republic of China; National Natural Science Foundation of China","keywords":"Long-term potentiation; NMDA receptor; Psychopharmacology; Neuroscience; Fear conditioning; Hippocampal formation; Psychology; Hippocampus; Conditioning; Synaptic plasticity; Receptor; Medicine; Psychiatry; Amygdala; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.050905043609654,"gpt":0.319550963996859,"spread":0.268645920387205,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006142462,0.0001097861,0.0001732283,0.0002753108,0.000120922,0.00001678914,0.0001789515,0.00005702608,0.000007769656],"category_scores_gemma":[0.0006017162,0.00009504606,0.00002565396,0.0004149142,0.0005334404,0.0001655409,0.00008723535,0.0002673131,7.625417e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002857705,"about_ca_system_score_gemma":0.00007870876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008445622,"about_ca_topic_score_gemma":0.00002970364,"domain_scores_codex":[0.997843,0.0008731132,0.0003187711,0.000366962,0.0003755028,0.0002227032],"domain_scores_gemma":[0.9993201,0.0003037382,0.0001483516,0.0001488863,0.00003359858,0.00004536053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001225589,0.000105692,0.005312589,0.0000290386,0.000002454195,0.0003239464,0.001460693,0.00008854616,0.9918179,0.0001870355,0.00003590823,0.0005136301],"study_design_scores_gemma":[0.001760256,0.0005210176,0.01137663,0.00003911645,0.000003667624,0.0001788667,0.0006806909,0.0003863208,0.9847531,0.0001906464,0.00001342328,0.00009628591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925994,0.00001319732,0.00005942843,0.0005766865,0.00005588338,0.00664713,0.000001806356,0.00000692738,0.00003949934],"genre_scores_gemma":[0.9972914,0.00001781996,0.000008618664,0.0009425845,0.000007963924,0.001702266,7.304326e-7,0.000009029668,0.00001955779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007064831,"threshold_uncertainty_score":0.3875866,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2641847409","doi":"10.1186/s13041-017-0308-9","title":"Synaptoimmunology - roles in health and disease","year":2017,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":52,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Medical Research Council","keywords":"Neuroscience; Immune system; Synaptic plasticity; Disease; Neurology; Neuroplasticity; Biology; Neuroimmunology; Nervous system; Central nervous system; Psychology; Immunology; Medicine; Receptor","retraction":null,"screen_n_in":null,"score":{"opus":0.0982621808646301,"gpt":0.3773973636297496,"spread":0.2791351827651195,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002645721,0.0003101647,0.0008012009,0.0003128072,0.0001864891,0.0001371824,0.0004014544,0.0001147055,0.00001949043],"category_scores_gemma":[0.002737991,0.0002929498,0.0001462779,0.0001234776,0.0001029032,0.00008129679,0.0001812919,0.0003422474,0.00007104059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003664721,"about_ca_system_score_gemma":0.0004966352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002316542,"about_ca_topic_score_gemma":0.000003050438,"domain_scores_codex":[0.9971061,0.001170663,0.0005166184,0.0007223138,0.000180997,0.0003033345],"domain_scores_gemma":[0.9984306,0.0001708832,0.0004209451,0.0006846708,0.000007530825,0.0002853874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000006883954,0.00004091637,3.117744e-7,0.003401597,0.000004838346,0.0008389608,0.00002948348,0.000003121638,0.006500745,0.04137227,0.0003173372,0.9474835],"study_design_scores_gemma":[0.0001982249,0.00004327982,8.141678e-7,0.001546923,0.00001145819,0.00008064906,0.000001161871,0.00005171288,0.0009131772,0.0008294789,0.9960622,0.0002609203],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001841854,0.9961709,0.000226016,0.002254038,0.0001585173,0.0007680731,0.00002914135,0.00007033495,0.0001387402],"genre_scores_gemma":[0.00009769991,0.9948133,0.00003642426,0.004168819,0.00002111085,0.0000904704,0.00002518445,0.00005514795,0.0006918857],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9957449,"threshold_uncertainty_score":0.9999523,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2135162718","doi":"10.1186/1756-6606-5-6","title":"Rapid synaptic potentiation within the anterior cingulate cortex mediates trace fear learning","year":2012,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":52,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Fear conditioning; Memory consolidation; AMPA receptor; Neuroscience; Anterior cingulate cortex; Long-term potentiation; Synaptic plasticity; Fear processing in the brain; NMDA receptor; Psychology; Extinction (optical mineralogy); Glutamate receptor; Hippocampus; Chemistry; Amygdala; Receptor; Cognition","retraction":null,"screen_n_in":null,"score":{"opus":0.02329469791319722,"gpt":0.3024680960174242,"spread":0.279173398104227,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001055869,0.0001766643,0.0001574872,0.0001300751,0.0005261689,0.0001166425,0.0004992076,0.00006359143,0.0001432828],"category_scores_gemma":[0.00215118,0.0001317156,0.00009259018,0.0005514147,0.0003550632,0.0003058611,0.0001712877,0.0005692875,0.0002310605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002220651,"about_ca_system_score_gemma":0.00004700059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004490906,"about_ca_topic_score_gemma":5.458155e-7,"domain_scores_codex":[0.9969871,0.001148675,0.0002413666,0.0004371607,0.0005314137,0.0006542967],"domain_scores_gemma":[0.9989126,0.0004731544,0.0001398144,0.000272563,0.00002820894,0.0001737103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002380672,0.00005663216,0.0005002133,0.000007591285,0.000005096609,0.0001027391,0.0004211558,0.0001115088,0.9974722,0.0001886868,0.0001452967,0.0009651036],"study_design_scores_gemma":[0.00032566,0.0001349253,0.005404413,0.000009656442,0.00001586384,0.0001730945,0.00005312324,0.004500905,0.9882377,0.00004968511,0.0009393382,0.0001556679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943129,0.0003297512,0.0003200304,0.003673801,0.0006228421,0.0003545708,0.000001985617,0.0001088647,0.0002752811],"genre_scores_gemma":[0.9949376,0.00005747792,0.00001474697,0.003893564,0.00008388119,0.00002716355,5.611074e-7,0.00003613574,0.0009489002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009234502,"threshold_uncertainty_score":0.5371205,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3010770968","doi":"10.1186/s13041-020-0563-z","title":"Tripartite signalling by NMDA receptors","year":2020,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":52,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Ionotropic effect; NMDA receptor; Biology; AMPA receptor; Cell biology; Glutamate receptor; Neuroscience; Receptor; Ionotropic glutamate receptor; Glutamatergic; Silent synapse; Class C GPCR; Biochemistry; Metabotropic glutamate receptor","retraction":null,"screen_n_in":null,"score":{"opus":0.09281259478187436,"gpt":0.3972536930044068,"spread":0.3044410982225324,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003684764,0.0005727124,0.001238122,0.0002602341,0.0002495004,0.0001817122,0.001516245,0.0002610181,0.000274241],"category_scores_gemma":[0.001501611,0.0005114164,0.0005841457,0.001719228,0.000343808,0.0001271294,0.0004200018,0.001363895,0.001525133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007082856,"about_ca_system_score_gemma":0.0003597955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001614035,"about_ca_topic_score_gemma":1.053963e-7,"domain_scores_codex":[0.9942567,0.001911516,0.0005965846,0.001608036,0.0007631952,0.0008639891],"domain_scores_gemma":[0.9978971,0.0009479342,0.0002633087,0.000425864,0.00002134022,0.0004444792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005622334,0.00005423768,4.53843e-8,0.0008396176,0.000009411841,0.0007790962,0.00001525423,8.660502e-7,0.6230665,0.00005940357,0.03067556,0.3444944],"study_design_scores_gemma":[0.000137232,0.00009459481,2.010539e-9,0.0003152861,0.00004685997,0.00003347942,8.855304e-7,0.00001794667,0.2712649,0.00001410133,0.7277599,0.0003147748],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001362307,0.9954651,0.0002667701,0.001168032,0.0007810625,0.001276845,0.00008347417,0.0002151131,0.0006073435],"genre_scores_gemma":[0.00004091336,0.9903147,0.00001421599,0.006947917,0.0001110462,0.0001767563,0.000009797389,0.0001426855,0.002241981],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6970844,"threshold_uncertainty_score":0.9997337,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}