{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":109,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":109,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"query_hash":"f495e7fae348","filters":{"venue":"Nature Reviews Molecular Cell Biology"}},"results":[{"id":"W1595083713","doi":"10.1038/35052055","title":"Rab proteins as membrane organizers","year":2001,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3360,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa","funders":"","keywords":"Rab; Organelle; Endocytic cycle; Vesicle; Cell biology; Vesicular transport protein; Biology; Compartment (ship); Membrane transport; Effector; Chemistry; Cell; Biochemistry; Membrane; Endocytosis; GTPase","retraction":null,"screen_n_in":null,"score":{"opus":0.01291264920215513,"gpt":0.2884233973637903,"spread":0.2755107481616352,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006425192,0.001176845,0.002747512,0.0002241743,0.000113633,0.00003481623,0.0009683037,0.004460448,0.0003902019],"category_scores_gemma":[0.0001869938,0.0009273896,0.001862187,0.0006785654,0.0001672403,0.000004092449,0.000182906,0.001668432,0.0006136976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006633427,"about_ca_system_score_gemma":0.0004367753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001229234,"about_ca_topic_score_gemma":0.00001162498,"domain_scores_codex":[0.9953828,0.000851129,0.001212107,0.001585088,0.0002070861,0.0007617179],"domain_scores_gemma":[0.9973385,0.00002062008,0.000768363,0.001477098,0.0001289896,0.0002663662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003313908,0.0001550073,0.000003805376,0.01342148,0.0003320419,0.0001978751,0.000009303166,4.547601e-7,0.1845244,0.000280306,0.0005787417,0.8004634],"study_design_scores_gemma":[0.0003402886,0.0002908271,8.099721e-8,0.001612184,0.0009130844,0.0001576945,0.000002172964,2.443519e-7,0.007424457,0.00003032983,0.9882745,0.0009541207],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003352231,0.9835913,0.002367201,0.00003019477,0.0005769139,0.003180729,0.00005499941,0.0000446839,0.01012043],"genre_scores_gemma":[0.00003694695,0.9665687,0.0006355802,0.0005466454,0.0005599433,0.0003148753,0.02911435,0.000200136,0.002022792],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9876958,"threshold_uncertainty_score":0.9993176,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3016840787","doi":"10.1038/s41580-020-0237-9","title":"Guidelines and definitions for research on epithelial–mesenchymal transition","year":2020,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":2301,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Environmental Health Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; Biotechnology and Biological Sciences Research Council; Wellcome Trust","keywords":"Terminology; Epithelial–mesenchymal transition; Conceptual framework; Biology; Data science; Computational biology; Bioinformatics; Computer science; Metastasis; Cancer; Sociology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.3261910674218622,"gpt":0.5012088399605845,"spread":0.1750177725387223,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.001374675,0.0005197277,0.002964626,0.000367995,0.0001188427,0.00001976067,0.00018254,0.001320773,0.00005666306],"category_scores_gemma":[0.0007892666,0.0003533572,0.00121651,0.000590139,0.000150774,0.00001405316,0.0000580265,0.001944702,0.0001024812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001044892,"about_ca_system_score_gemma":0.0004363924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005748958,"about_ca_topic_score_gemma":0.000002493837,"domain_scores_codex":[0.9965383,0.0008396588,0.0009788072,0.0009586274,0.0002060864,0.0004784823],"domain_scores_gemma":[0.9982108,0.0003771358,0.0002725974,0.0005206396,0.0003513162,0.0002674633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000378761,0.00005315535,2.647565e-8,0.02691736,0.00008931474,0.00004722627,0.00001009123,5.659019e-8,0.0003775183,0.001664142,0.007319516,0.9634837],"study_design_scores_gemma":[0.0005020283,0.0007270149,2.496269e-8,0.008664479,0.00181603,0.00008078849,0.000005080244,0.000001939419,0.0001547937,0.0002905552,0.9874811,0.000276175],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[9.804246e-7,0.9890036,0.0007817445,0.001828264,0.0003002478,0.004431098,0.0005749826,0.00002802358,0.003051073],"genre_scores_gemma":[0.00000468195,0.9869102,0.007142926,0.002556082,0.0007065504,0.0008658047,0.001614692,0.00008355441,0.0001154901],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9801615,"threshold_uncertainty_score":0.9999757,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2005496979","doi":"10.1038/nrm2820","title":"Sensors and regulators of intracellular pH","year":2009,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2286,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Hospital for Sick Children; University of Alberta","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Cytosol; Biophysics; Intracellular; Proton; Intracellular pH; Organelle; Function (biology); Chemistry; Proton transport; Cell biology; Biochemistry; Biology; Physics; Membrane","retraction":null,"screen_n_in":null,"score":{"opus":0.01653754734422223,"gpt":0.3383207085449296,"spread":0.3217831612007074,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006887928,0.0007418977,0.002524382,0.0002149998,0.00006699277,0.00001620065,0.0005748387,0.002709737,0.00002773169],"category_scores_gemma":[0.0003091676,0.0005577839,0.001005249,0.0003430201,0.0002851044,0.000002788844,0.0003027156,0.00109979,0.0000238742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000303123,"about_ca_system_score_gemma":0.0002140231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000299952,"about_ca_topic_score_gemma":9.790358e-7,"domain_scores_codex":[0.9961351,0.001059593,0.001012079,0.001078187,0.0001684522,0.0005466541],"domain_scores_gemma":[0.9978313,0.00005286945,0.000692417,0.001110953,0.0001065614,0.000205864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001078071,0.0000604021,0.000002389131,0.007672932,0.0001335042,0.00003394748,0.000003115485,2.936841e-7,0.04091557,0.0001684803,0.0008104919,0.9501881],"study_design_scores_gemma":[0.0001702049,0.000318628,2.569245e-7,0.00182951,0.0004232296,0.00003123254,0.000002018532,9.588297e-7,0.01851488,0.00004418374,0.9781705,0.0004944245],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007739717,0.9964516,0.0001179752,0.00003064287,0.0001202235,0.001269463,0.00005157102,0.00001106534,0.001173464],"genre_scores_gemma":[0.000358736,0.9971351,0.0008331148,0.0001285629,0.0002288845,0.0000519988,0.0007955887,0.00007913497,0.0003888778],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.97736,"threshold_uncertainty_score":0.9996874,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2017739035","doi":"10.1038/nrm3330","title":"The functions and regulation of the PTEN tumour suppressor","year":2012,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1920,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; Ontario Institute for Cancer Research","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"PTEN; Tensin; PI3K/AKT/mTOR pathway; Phosphatase; Biology; Suppressor; Protein kinase B; Cell biology; Function (biology); Cancer research; Mechanistic target of rapamycin; Signal transduction; Phosphorylation; Cancer; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.01856843515653857,"gpt":0.3026431238135093,"spread":0.2840746886569707,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008241642,0.0004763879,0.001036405,0.00004938352,0.0001817334,0.00001924855,0.0007279902,0.001471896,0.00001851481],"category_scores_gemma":[0.0002669467,0.0002445862,0.0007945447,0.0002424133,0.0003273047,0.000002934702,0.0003846309,0.0008566407,0.00001560133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003044559,"about_ca_system_score_gemma":0.0001937102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003442396,"about_ca_topic_score_gemma":0.000007113642,"domain_scores_codex":[0.9970123,0.001165487,0.0007346953,0.0005691152,0.0001325718,0.0003858615],"domain_scores_gemma":[0.9976104,0.00009772084,0.0009207737,0.001176427,0.00011629,0.00007832072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001300926,0.00003468479,0.00001388156,0.004208306,0.0002293871,5.473727e-7,0.000005571878,0.000001229282,0.08611269,0.000447214,0.004099631,0.9048339],"study_design_scores_gemma":[0.0001010976,0.00005897773,0.000005103749,0.0007829236,0.0008375257,0.00002630624,0.000001494747,8.114973e-7,0.00546852,0.00003923914,0.9924206,0.0002574326],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000351462,0.9957274,0.0001457677,0.00006170773,0.001017243,0.00125382,0.0000812143,0.000007149355,0.001670602],"genre_scores_gemma":[0.001517151,0.9961927,0.00012046,0.0001356289,0.0004329951,0.0002011419,0.0003307818,0.0000592487,0.001009883],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9883209,"threshold_uncertainty_score":0.9998244,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2734540391","doi":"10.1038/nrm.2017.60","title":"Genes and molecular pathways underpinning ciliopathies","year":2017,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1688,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Simon Fraser University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Michael Smith Health Research BC","keywords":"Ciliopathies; Cilium; Ciliopathy; Ciliogenesis; Intraflagellar transport; Biology; Cell biology; Motile cilium; Exocyst; Neuroscience; Phenotype; Genetics; Gene; Flagellum","retraction":null,"screen_n_in":0,"score":{"opus":0.03696051252122351,"gpt":0.3335075058825498,"spread":0.2965469933613263,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005911805,0.001187951,0.002734361,0.0002126705,0.0002546227,0.0001086408,0.001088582,0.002831816,0.00001971262],"category_scores_gemma":[0.000540356,0.0009436305,0.001310381,0.0001524629,0.0004081242,0.00000498633,0.0007872992,0.0009584571,0.00006939828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003007522,"about_ca_system_score_gemma":0.0005266331,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004431554,"about_ca_topic_score_gemma":0.000002130961,"domain_scores_codex":[0.9954966,0.0009553877,0.000970409,0.001664558,0.0001737573,0.0007393002],"domain_scores_gemma":[0.9965081,0.00003368487,0.001004639,0.001942559,0.0001167711,0.0003942488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000008645576,0.00005166479,0.000004656275,0.0108347,0.0002303447,0.0001076786,0.000005059819,3.069403e-7,0.03507955,0.0002184223,0.001107093,0.9523519],"study_design_scores_gemma":[0.0002549241,0.0002152522,7.95655e-7,0.002482019,0.001030238,0.00009911152,0.000004470704,7.180768e-7,0.003069835,0.0001763436,0.9916945,0.0009718082],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007353552,0.9933391,0.0006009104,0.00003157284,0.0004591802,0.001515796,0.0001676992,0.00002981687,0.003782447],"genre_scores_gemma":[0.000539834,0.9948935,0.001257501,0.0007071589,0.0002601572,0.0002985114,0.001636772,0.0001519122,0.0002546408],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9905874,"threshold_uncertainty_score":0.9993014,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1970661950","doi":"10.1038/nrm3565","title":"Signals from the lysosome: a control centre for cellular clearance and energy metabolism","year":2013,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":1676,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Institute of Genetics; National Institute of Neurological Disorders and Stroke","keywords":"TFEB; Autophagy; Lysosome; Cell biology; Biogenesis; Biology; Transcription factor; Regulator; Biochemistry; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.01483263211796034,"gpt":0.3007965551080002,"spread":0.2859639229900399,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003983993,0.0008062822,0.004128946,0.00008631287,0.00009708785,0.00003171966,0.000452528,0.001740395,0.0002349672],"category_scores_gemma":[0.0001839726,0.0004233679,0.001667825,0.0002237838,0.0001710818,0.00002641128,0.00006977486,0.001022291,0.00008427193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003383109,"about_ca_system_score_gemma":0.0001810702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001899172,"about_ca_topic_score_gemma":9.694213e-7,"domain_scores_codex":[0.9963382,0.001159985,0.0009209902,0.0009163519,0.0001483636,0.0005160408],"domain_scores_gemma":[0.9973413,0.000546051,0.0007512581,0.0009999368,0.0001267986,0.000234619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004301734,0.00006692344,6.054374e-7,0.004458187,0.0007746203,0.00003262705,0.00001036359,4.305818e-8,0.001589268,0.001315088,0.003733773,0.9879755],"study_design_scores_gemma":[0.001232658,0.00007190463,7.567109e-7,0.003264097,0.005346516,0.00001038996,0.000002117485,0.000007631996,0.0004627194,0.0005225339,0.9886937,0.0003849769],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001237639,0.9940136,0.0011672,0.0003336393,0.0003860506,0.003403341,0.0003422578,0.00003460344,0.0003069193],"genre_scores_gemma":[0.0001067943,0.9890776,0.0004950818,0.007035838,0.000748117,0.0007766368,0.001107026,0.0001083219,0.0005446027],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9875905,"threshold_uncertainty_score":0.9998218,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2087963453","doi":"10.1038/nrm1490","title":"Integrin signalling during tumour progression","year":2004,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":1462,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Hakai Institute; National Institutes of Health","keywords":"Integrin; Receptor tyrosine kinase; Metastasis; Biology; Cell biology; Receptor Protein-Tyrosine Kinases; Cancer research; Signalling; Tyrosine kinase; Signal transduction; Receptor; Cancer; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.03218577771305046,"gpt":0.3966335911253059,"spread":0.3644478134122555,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.001001341,0.001232866,0.005059551,0.0008149394,0.0001255253,0.00004380766,0.0008305485,0.003443199,0.0003640189],"category_scores_gemma":[0.0007104332,0.0008078947,0.002448938,0.001151914,0.0001839141,0.00003339789,0.0005536735,0.006982243,0.001217823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007169478,"about_ca_system_score_gemma":0.001056463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004023771,"about_ca_topic_score_gemma":7.569571e-7,"domain_scores_codex":[0.9936697,0.001299233,0.00173283,0.001662842,0.0005452987,0.001090044],"domain_scores_gemma":[0.9969997,0.0001387985,0.0009100513,0.001199365,0.0002201294,0.0005319183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002889031,0.0001853701,0.000001553904,0.1193801,0.0001232171,0.001453752,0.000007471343,3.37338e-7,0.02392165,0.0001007359,0.0001043425,0.8546926],"study_design_scores_gemma":[0.0005923928,0.0002971527,4.538958e-7,0.07080084,0.0009990368,0.0004574155,0.000001815403,0.000001182269,0.005455902,0.00003495461,0.9207367,0.0006221007],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002519095,0.9895132,0.000218257,0.00006257621,0.0002905491,0.005329633,0.00001471922,0.000119477,0.004426391],"genre_scores_gemma":[0.00008093533,0.993109,0.00403665,0.0001736321,0.0003131305,0.0004898578,0.0008238205,0.0002348339,0.0007380859],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9206324,"threshold_uncertainty_score":0.9995598,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2084459589","doi":"10.1038/nrm1618","title":"Translational control in stress and apoptosis","year":2005,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1388,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Children's Hospital of Eastern Ontario","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Internal ribosome entry site; Translation (biology); Translational regulation; Cell biology; Initiation factor; Integrated stress response; Ribosome; Eukaryotic initiation factor; Phosphorylation; Protein biosynthesis; EIF4E; Eukaryotic translation; Biology; Messenger RNA; Chemistry; Gene; Genetics; RNA","retraction":null,"screen_n_in":null,"score":{"opus":0.01344348124446622,"gpt":0.2989696831720907,"spread":0.2855262019276245,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005878811,0.0006449719,0.001859984,0.0001785826,0.00004248414,0.00002036066,0.0004154951,0.00251418,0.0000475813],"category_scores_gemma":[0.0001033338,0.0005051946,0.0006375128,0.0001789019,0.00008553505,0.000003069438,0.00007589332,0.0007430439,0.00002868125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001972716,"about_ca_system_score_gemma":0.0001346595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002623395,"about_ca_topic_score_gemma":0.000009983589,"domain_scores_codex":[0.9966281,0.001086181,0.0008218212,0.0009423401,0.0001019852,0.0004195913],"domain_scores_gemma":[0.9988433,0.00006064326,0.0003958454,0.0005481891,0.00003676266,0.0001153264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001053623,0.00004447665,0.000006404335,0.003240752,0.00006902128,0.000004021769,0.000002774479,7.017139e-7,0.008017013,0.0002329008,0.00007926104,0.9882922],"study_design_scores_gemma":[0.0003658226,0.00009558831,4.619955e-7,0.001847574,0.000285565,0.00001287913,8.066199e-7,0.000001104502,0.002348196,0.00005429275,0.9944932,0.0004945155],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001820377,0.995438,0.001287352,0.00005388936,0.0001683628,0.001705051,0.0001582239,0.000008484397,0.001162474],"genre_scores_gemma":[0.0004772241,0.9958178,0.001555789,0.0004832648,0.0002839251,0.0003734513,0.0008410232,0.00006700862,0.0001004475],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9944139,"threshold_uncertainty_score":0.9997399,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2082997857","doi":"10.1038/nrm2321","title":"Argonaute proteins: key players in RNA silencing","year":2007,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1362,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"Wellcome Trust","keywords":"Argonaute; RNA-induced silencing complex; Piwi-interacting RNA; RasiRNA; Gene silencing; Biology; Trans-acting siRNA; RNA silencing; microRNA; Non-coding RNA; RNA; Small RNA; RNA interference; Computational biology; Long non-coding RNA; Genetics; Cell biology; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.02523193568820789,"gpt":0.3238931074103224,"spread":0.2986611717221145,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.002049359,0.001190475,0.00295604,0.0004547684,0.00007886413,0.00003290334,0.001163583,0.004843379,0.00005692416],"category_scores_gemma":[0.000496988,0.0009453491,0.001431044,0.000595942,0.0001137981,0.000005245781,0.0003506072,0.001823598,0.0001982503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001152643,"about_ca_system_score_gemma":0.0003859338,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001184183,"about_ca_topic_score_gemma":0.00001592496,"domain_scores_codex":[0.9940789,0.001421468,0.001595895,0.001667464,0.0002197552,0.001016519],"domain_scores_gemma":[0.9972205,0.00007292348,0.0009987934,0.001411595,0.00007899968,0.0002172276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001709167,0.00005838554,5.426886e-7,0.006606506,0.00008324974,0.00008564302,0.000007644408,7.080878e-7,0.1150937,0.0003041617,0.0002425445,0.8774999],"study_design_scores_gemma":[0.0002401399,0.000223033,9.480645e-8,0.004971006,0.000217521,0.00004177755,0.000003483914,5.421821e-7,0.05763314,0.00007718959,0.9356813,0.0009107851],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005188265,0.9864057,0.002580968,0.00001216973,0.0005696839,0.003930097,0.00004406804,0.00002641909,0.006379056],"genre_scores_gemma":[0.0001010644,0.9912883,0.005493419,0.0006014855,0.000429439,0.0007140957,0.0007703975,0.0001677327,0.000434061],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9354388,"threshold_uncertainty_score":0.9992997,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2168448928","doi":"10.1038/nrm2346","title":"The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men","year":2008,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1214,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; American Heart Association","keywords":"Biology; HDAC4; Chromatin; Histone; Genetics; Histone deacetylase; Cell biology; Histone H4; Histone deacetylase 5; Histone deacetylase 2; Multiprotein complex; Epigenetics; DNA; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.01401483975906001,"gpt":0.3173181656081127,"spread":0.3033033258490527,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005370349,0.0007145992,0.002030779,0.0001474736,0.0001506501,0.00003275718,0.0006937952,0.00161548,0.000007333377],"category_scores_gemma":[0.0004605951,0.0004764285,0.0005213615,0.0003273354,0.0004460792,0.000003531772,0.0007002068,0.0008994603,0.00003870421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004619899,"about_ca_system_score_gemma":0.0002754078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004163321,"about_ca_topic_score_gemma":0.00001994296,"domain_scores_codex":[0.9958622,0.001255701,0.0009886165,0.001173403,0.0001903212,0.0005297563],"domain_scores_gemma":[0.9978042,0.0001396506,0.0005375944,0.001092173,0.0001561799,0.0002701628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004278549,0.00004432689,0.00000215106,0.002164473,0.000231085,0.00002302082,0.00001936221,7.75613e-8,0.3413995,0.00001853706,0.01095373,0.645101],"study_design_scores_gemma":[0.0002459821,0.0002424902,0.000003156093,0.001184869,0.0002229209,0.00005941547,0.000006693792,5.694439e-7,0.01228717,0.000005332074,0.9853051,0.0004362928],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003648868,0.9931446,0.00006494288,0.0000536638,0.0001866245,0.001705305,0.0003545477,0.000008426599,0.0008330297],"genre_scores_gemma":[0.0003163672,0.9964662,0.001235548,0.000215794,0.0002568392,0.0001825153,0.0009551687,0.00009049267,0.0002810505],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9743513,"threshold_uncertainty_score":0.9997687,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3036759197","doi":"10.1038/s41580-020-0255-7","title":"ERK signalling: a master regulator of cell behaviour, life and fate","year":2020,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1202,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Cell biology; MAPK/ERK pathway; Kinase; Biology; Cell growth; Cell fate determination; Extracellular; Cell; Signal transduction; Intracellular; Protein kinase A; Cell signaling; Regulator; Cell metabolism; Biochemistry; Transcription factor","retraction":null,"screen_n_in":null,"score":{"opus":0.02423147105711939,"gpt":0.280338448925497,"spread":0.2561069778683777,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0004151052,0.0008906986,0.002954596,0.000135216,0.00004848852,0.00001997868,0.0006430559,0.002651531,0.0000393802],"category_scores_gemma":[0.000166305,0.000685719,0.001127388,0.0002410203,0.0001656481,0.000002856562,0.0004643806,0.001031134,0.00004726786],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001723541,"about_ca_system_score_gemma":0.0003285641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000208982,"about_ca_topic_score_gemma":0.000001119882,"domain_scores_codex":[0.9960365,0.0008258116,0.001238013,0.001271387,0.0001426388,0.0004856866],"domain_scores_gemma":[0.9975317,0.00003593718,0.001111099,0.0008643043,0.00009764224,0.0003593235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005316558,0.0001867667,0.0000363835,0.04064915,0.0003573079,0.0001214218,0.00002547558,3.168288e-7,0.3102205,0.0002915961,0.003508069,0.6445498],"study_design_scores_gemma":[0.0003037116,0.000490658,5.262186e-7,0.001139284,0.0008313317,0.00003219335,0.000002465999,9.176763e-7,0.0163828,0.00001642982,0.9801877,0.0006120501],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002217076,0.9954433,0.0004956075,0.00002259957,0.0003000662,0.001535016,0.0001707343,0.00001501998,0.001795892],"genre_scores_gemma":[0.0009035242,0.9944055,0.002098944,0.0004859003,0.000306619,0.000126653,0.001275356,0.0001178796,0.0002796374],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9766796,"threshold_uncertainty_score":0.9995594,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2071497196","doi":"10.1038/nrm2717","title":"Proximal events in Wnt signal transduction","year":2009,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1112,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"LRP6; Wnt signaling pathway; LRP5; Frizzled; Cell biology; Biology; Signal transduction; Receptor; Progenitor cell; Stem cell; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.01653384104136349,"gpt":0.312151532276147,"spread":0.2956176912347835,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008185259,0.000866474,0.002047159,0.000257987,0.0000537291,0.00001221624,0.0007184017,0.002878003,0.0001124473],"category_scores_gemma":[0.00005829096,0.0006896975,0.001030504,0.0004779769,0.00007458145,0.000004525128,0.0001047239,0.001380835,0.00008014742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001142625,"about_ca_system_score_gemma":0.0004129051,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002728731,"about_ca_topic_score_gemma":0.000005397194,"domain_scores_codex":[0.9958174,0.0009238827,0.001170807,0.001267412,0.0001739632,0.0006465327],"domain_scores_gemma":[0.9986653,0.00001671364,0.0005643174,0.0005600039,0.00007340778,0.0001203106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002665182,0.0001171663,0.00001047,0.004021293,0.00009394974,0.00001907333,0.000006973245,0.000002101943,0.01058272,0.00004044371,0.001004616,0.9840745],"study_design_scores_gemma":[0.0003446137,0.0002294709,0.000001611421,0.002636956,0.0002727961,0.00003347135,0.00000106312,4.49106e-7,0.004534765,0.00008051197,0.9911268,0.0007374582],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008285075,0.9956449,0.0003993502,0.0000286044,0.0004855903,0.001927141,0.00001693915,0.00001892587,0.001395716],"genre_scores_gemma":[0.0004050996,0.9947357,0.001038131,0.0003550304,0.0004489554,0.0004037017,0.002026939,0.00008316963,0.0005032747],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9901222,"threshold_uncertainty_score":0.9995554,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2005441809","doi":"10.1038/nrm2434","title":"Cytochrome c: functions beyond respiration","year":2008,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1106,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Cytochrome c; Apoptosis; Apoptosome; Mitochondrion; Cytochrome; Cell biology; Cytochrome b; Biology; Cytosol; Programmed cell death; Mitochondrial apoptosis-induced channel; Intrinsic apoptosis; Biochemistry; Caspase; Mitochondrial DNA; Gene; Enzyme","retraction":null,"screen_n_in":null,"score":{"opus":0.01762449773476279,"gpt":0.3074600017338097,"spread":0.289835503999047,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003452467,0.0008372423,0.001830974,0.0002605196,0.0001955107,0.00002706195,0.0004897907,0.003640136,0.00007657733],"category_scores_gemma":[0.0001324686,0.0006438987,0.00151489,0.0004344522,0.0001229832,0.000004796955,0.0002253502,0.001032141,0.0003200732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006954232,"about_ca_system_score_gemma":0.000306142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000315036,"about_ca_topic_score_gemma":0.0000052581,"domain_scores_codex":[0.9962232,0.0008020357,0.00104277,0.00126752,0.0001631035,0.0005013905],"domain_scores_gemma":[0.9976674,0.00002504231,0.0007841875,0.001231136,0.00012938,0.0001628965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007164916,0.00006224476,2.797802e-7,0.002291793,0.0001077474,0.00001890397,0.000002775124,0.000002476587,0.02246849,0.000305155,0.006291986,0.968441],"study_design_scores_gemma":[0.0002011069,0.0002997525,3.053254e-7,0.0006595625,0.000396906,0.0001546519,7.691008e-7,0.000001826984,0.0006464474,0.00005258102,0.9969347,0.0006514438],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000006439209,0.986652,0.004048245,0.00001587236,0.0008115185,0.00191379,0.00007942855,0.00003249456,0.006440276],"genre_scores_gemma":[0.00001875728,0.9869059,0.001148992,0.0003958399,0.0007863162,0.0003361099,0.007909631,0.000120811,0.002377674],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9906427,"threshold_uncertainty_score":0.9996012,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2079139546","doi":"10.1038/nrm1492","title":"Pathways of chaperone-mediated protein folding in the cytosol","year":2004,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1105,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"","keywords":"Chaperone (clinical); Cytosol; Co-chaperone; Protein folding; Ribosome; Cell biology; Folding (DSP implementation); Chemistry; Chaperonin; Biochemistry; Biophysics; Biology; Computational biology; Hsp90; Enzyme; RNA; Heat shock protein; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.03152017049737355,"gpt":0.3430252240341532,"spread":0.3115050535367797,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00215558,0.0008017888,0.002367468,0.0003245994,0.00006493345,0.00002075687,0.001753514,0.003095196,0.00002740614],"category_scores_gemma":[0.001160272,0.0005041413,0.001077124,0.0008818161,0.0002278371,0.000003837467,0.0004428049,0.002300118,0.00007591584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001089366,"about_ca_system_score_gemma":0.000927164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001825938,"about_ca_topic_score_gemma":0.00001305581,"domain_scores_codex":[0.9935554,0.002752356,0.001417171,0.001133563,0.0003146008,0.0008269209],"domain_scores_gemma":[0.9974048,0.00008403482,0.000663434,0.001609425,0.0001155472,0.0001227443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000022676,0.0002652917,0.000002463618,0.03516515,0.0001266976,0.0001166616,0.00003834151,0.0000012846,0.2760212,0.0007475908,0.0001083877,0.6873842],"study_design_scores_gemma":[0.0003531493,0.0004820285,2.135113e-7,0.00618345,0.0001036638,0.00003397425,0.000005687646,5.493175e-7,0.01297939,0.00005549863,0.9793378,0.0004646068],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002190042,0.9914959,0.0001988123,0.00004007218,0.00009163844,0.006364232,0.00009507324,0.00001059472,0.001484654],"genre_scores_gemma":[0.002475108,0.9935015,0.000682534,0.0001798666,0.0001490292,0.001492543,0.001371575,0.0001011382,0.00004675051],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9792294,"threshold_uncertainty_score":0.999741,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2792980560","doi":"10.1038/nrm1151","title":"Phospholamban: a crucial regulator of cardiac contractility","year":2003,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":1076,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Phospholamban; Contractility; Heart failure; Dilated cardiomyopathy; Endoplasmic reticulum; Internal medicine; Cardiomyopathy; Regulator; Cardiology; Medicine; Endocrinology; Chemistry; Biology; Cell biology; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.01316749003212946,"gpt":0.3244175617857238,"spread":0.3112500717535943,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0009109117,0.0008743933,0.008560503,0.0002034428,0.00005788997,0.000005703471,0.0002572519,0.003842144,0.0001274094],"category_scores_gemma":[0.0005121598,0.0006224649,0.004708464,0.0005928669,0.0003049865,0.00002332298,0.00008725985,0.003177172,0.0001176095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001515738,"about_ca_system_score_gemma":0.0007743755,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003862523,"about_ca_topic_score_gemma":2.573849e-7,"domain_scores_codex":[0.9946845,0.001970551,0.001482302,0.001070569,0.0001775734,0.0006145571],"domain_scores_gemma":[0.9967515,0.0002152512,0.001203681,0.001425138,0.0001943319,0.0002100215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006371039,0.0001110284,0.000002616697,0.02176802,0.0006235091,0.0001331705,0.000004169095,3.128361e-8,0.002291232,0.0008949311,0.001582629,0.9725249],"study_design_scores_gemma":[0.0002813916,0.0002648028,0.00000332095,0.003823788,0.004158564,0.0001969664,6.569017e-7,9.340489e-8,0.001106051,0.00006083271,0.9896702,0.0004333328],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005200542,0.9872597,0.00001296557,0.00002081702,0.001182593,0.003254965,0.0001098718,0.0000319447,0.008075085],"genre_scores_gemma":[0.00009318478,0.9971677,0.0005591037,0.0004561289,0.0003931305,0.0002133001,0.0005929538,0.00008419371,0.0004402901],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9880876,"threshold_uncertainty_score":0.9996226,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2126920991","doi":"10.1038/nrm1527","title":"AKAP signalling complexes: focal points in space and time","year":2004,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1075,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institutes of Health; Heart and Stroke Foundation of Canada","keywords":"Kinase; Phosphorylation; Phosphatase; Cell biology; Second messenger system; Signalling; Signal transduction; Enzyme; Intracellular; Protein kinase A; Biology; Chemistry; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.01490486060901404,"gpt":0.2999336621695693,"spread":0.2850288015605553,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008166603,0.0007887313,0.002123541,0.0002586934,0.00006674034,0.00003284198,0.0004124147,0.002324593,0.00004959267],"category_scores_gemma":[0.00020725,0.0006536756,0.0006768013,0.0003465288,0.0001645891,0.000004049342,0.0002846592,0.001122902,0.0001025338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008421153,"about_ca_system_score_gemma":0.0002891021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006340975,"about_ca_topic_score_gemma":0.000002795964,"domain_scores_codex":[0.9962485,0.0009420592,0.0009590674,0.001172802,0.0001280341,0.0005494929],"domain_scores_gemma":[0.9985665,0.00004230406,0.0005565382,0.000595224,0.00005955737,0.000179878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003454112,0.0001579629,0.000004111621,0.024146,0.0001727475,0.000150152,0.00001670638,0.00001739725,0.09783895,0.003373857,0.000270916,0.8738167],"study_design_scores_gemma":[0.0004236707,0.0001471553,2.183455e-7,0.006860215,0.0001988238,0.0000638581,0.000001103491,0.000007974798,0.00344875,0.000441143,0.987748,0.0006591413],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003395998,0.9952667,0.001550067,0.00004048507,0.0001009836,0.001761749,0.00003909552,0.000018542,0.001188405],"genre_scores_gemma":[0.0002733267,0.9940706,0.003403197,0.0003305073,0.0001690625,0.000133628,0.001394756,0.00009051627,0.0001343658],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.987477,"threshold_uncertainty_score":0.9995915,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2004250476","doi":"10.1038/nrm2690","title":"Physiological functions of the HECT family of ubiquitin ligases","year":2009,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1074,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Ubiquitin ligase; Ubiquitin; NEDD4; Ubiquitin-Protein Ligases; Cell biology; Biology; Proteasome; Enzyme; Ubiquitin-conjugating enzyme; Biochemistry; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.03233432371193184,"gpt":0.3147243350992998,"spread":0.282390011387368,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005670142,0.0006663314,0.002464269,0.0001018556,0.00006883548,0.000006424691,0.001055953,0.002256313,0.00003040393],"category_scores_gemma":[0.0004487387,0.0003853835,0.002333763,0.0004608037,0.0003230509,0.000001839052,0.0003772588,0.001073062,0.00002371766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002049864,"about_ca_system_score_gemma":0.0003135917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003672332,"about_ca_topic_score_gemma":0.000001563667,"domain_scores_codex":[0.9958414,0.001588203,0.001207371,0.0008013065,0.0001503614,0.0004113232],"domain_scores_gemma":[0.9970145,0.00005847766,0.001351943,0.001339759,0.0001487998,0.00008649341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001469763,0.0001741427,0.000002434863,0.007414239,0.0001474208,0.000003089553,0.000003473105,0.0000010381,0.2505719,0.000295745,0.003213222,0.7381586],"study_design_scores_gemma":[0.0001383915,0.0005302437,0.000003169014,0.002467614,0.000484756,0.00001689417,0.000002474531,1.760416e-7,0.04340891,0.00007053943,0.9525313,0.0003455127],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00035178,0.9927151,0.0001056372,0.0000158581,0.0003394676,0.001677717,0.0002613212,0.00001105638,0.004522089],"genre_scores_gemma":[0.001643164,0.9960833,0.0003909353,0.0004565071,0.0002432993,0.0001406334,0.0007513091,0.00004558918,0.0002452321],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9493181,"threshold_uncertainty_score":0.9998598,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2041677910","doi":"10.1038/nrm2927","title":"Adherens junctions: from molecules to morphogenesis","year":2010,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":978,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Adherens junction; Morphogenesis; Cell biology; Cilium; Endocytic cycle; Biology; Cadherin; Microtubule; Actin; Cell; Endocytosis; Gene; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.01917185007673264,"gpt":0.3177447238776193,"spread":0.2985728738008867,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004710387,0.001180458,0.002415121,0.0002584875,0.0001299853,0.00005413362,0.001283702,0.004169284,0.0003283226],"category_scores_gemma":[0.0003197356,0.0009384452,0.001455002,0.0005529548,0.0001280865,0.000003465227,0.0005056664,0.001575568,0.0009135695],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000672188,"about_ca_system_score_gemma":0.0004839252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001822202,"about_ca_topic_score_gemma":0.00002596576,"domain_scores_codex":[0.995415,0.0006634817,0.001174711,0.001815141,0.0002078988,0.0007238154],"domain_scores_gemma":[0.9972326,0.00004787252,0.0006563701,0.001550981,0.0001843715,0.0003278498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001469611,0.00005975052,0.000004843273,0.001331822,0.0002700434,0.00002032477,0.000005294942,9.459447e-7,0.09693661,0.00004164733,0.02167124,0.8796428],"study_design_scores_gemma":[0.0001879874,0.0001347483,5.861273e-7,0.001420465,0.0007728044,0.00001652515,0.00000181383,2.304843e-7,0.01397513,0.00004020963,0.9823858,0.001063659],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007492549,0.9911892,0.00175229,0.00003802962,0.002216934,0.001948993,0.0002783862,0.00004395813,0.002457332],"genre_scores_gemma":[0.00001690103,0.9788834,0.01057436,0.001527498,0.0009709327,0.001070087,0.005414312,0.0001922167,0.001350254],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9607146,"threshold_uncertainty_score":0.9998643,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2012080977","doi":"10.1038/nrm2821","title":"Regulation of cell signalling by uPAR","year":2009,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":968,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Urokinase receptor; Vitronectin; Cell biology; Integrin; Receptor; Plasminogen activator; Signal transduction; Extracellular matrix; Chemistry; Intracellular; Extracellular; Cell migration; SuPAR; Urokinase; Biology; Cell; Biochemistry; Endocrinology","retraction":null,"screen_n_in":null,"score":{"opus":0.01178546432210058,"gpt":0.2878824870949926,"spread":0.276097022772892,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006200198,0.0007631583,0.002205664,0.0001423797,0.00005360657,0.00001347244,0.0006591457,0.003145522,0.0000419538],"category_scores_gemma":[0.00009766091,0.0006133729,0.001307246,0.0002847927,0.00007206717,0.000003802521,0.0001532523,0.0008957729,0.00005182672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003567355,"about_ca_system_score_gemma":0.0001981503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001804703,"about_ca_topic_score_gemma":3.744038e-7,"domain_scores_codex":[0.9962794,0.0008665927,0.001208515,0.001021772,0.0001591006,0.0004645857],"domain_scores_gemma":[0.9975231,0.00002283313,0.001280212,0.0009224729,0.0001152031,0.0001361269],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000006401339,0.00006878913,5.630087e-8,0.004303907,0.00004014371,0.000002519651,0.000001137332,3.876251e-7,0.652221,0.00008262994,0.004018025,0.339255],"study_design_scores_gemma":[0.0001252892,0.0002726041,6.629501e-9,0.001279896,0.0003141234,0.000005809039,3.378361e-7,8.00678e-7,0.354114,0.000093658,0.6434254,0.0003680858],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001307595,0.9918275,0.002531442,0.000007828566,0.000250542,0.001630497,0.0001024634,0.00001511915,0.003621495],"genre_scores_gemma":[0.0003756509,0.9922054,0.002194358,0.0002979783,0.0002917888,0.0001039766,0.004002466,0.00008242814,0.0004459675],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6394074,"threshold_uncertainty_score":0.9996318,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4307715807","doi":"10.1038/s41580-022-00547-x","title":"New insights into activation and function of the AMPK","year":2022,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":955,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University; McMaster University Medical Centre","funders":"Canadian Institutes of Health Research; Cancer Research UK; Wellcome Trust","keywords":"AMPK; AMP-activated protein kinase; Protein kinase A; Energy homeostasis; Adenosine triphosphate; Cell biology; Catabolism; Glycogen; Phosphorylation; Biochemistry; Chemistry; Biology; Metabolism","retraction":null,"screen_n_in":null,"score":{"opus":0.01411527989096833,"gpt":0.2846837607482887,"spread":0.2705684808573204,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002959131,0.0004406464,0.001250269,0.00009498477,0.00009249558,0.00001037079,0.0004732367,0.001148405,0.0001004373],"category_scores_gemma":[0.0001743042,0.0002787811,0.0006677037,0.0003579091,0.00008614067,0.000003368135,0.0003585675,0.0008102212,0.000004882112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003590821,"about_ca_system_score_gemma":0.0003417888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001159904,"about_ca_topic_score_gemma":0.000007019542,"domain_scores_codex":[0.9974167,0.0009534562,0.0006033463,0.0006760453,0.0001316629,0.0002187985],"domain_scores_gemma":[0.9982553,0.00002813795,0.0007776885,0.0008159004,0.00004449022,0.0000785318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000716125,0.00001527612,9.276824e-7,0.003057474,0.00008756062,2.48183e-7,0.000009334296,2.094241e-7,0.005249897,0.0002857779,0.001971736,0.9893144],"study_design_scores_gemma":[0.0001666092,0.0001183793,9.151921e-7,0.0005188858,0.0005152795,0.000002191954,0.000002558418,1.523917e-7,0.004834678,0.0002330429,0.9933342,0.0002730665],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005533018,0.9965886,0.0005095536,0.000006867805,0.000922689,0.001072959,0.000009406968,0.000005732574,0.0008288042],"genre_scores_gemma":[0.00005101648,0.9978515,0.0002196175,0.0006007774,0.0003220343,0.000143774,0.0005539993,0.00004757106,0.0002097146],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9913625,"threshold_uncertainty_score":0.9999664,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2032189193","doi":"10.1038/nrm3522","title":"Amino acid signalling upstream of mTOR","year":2013,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":884,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; National Cancer Institute; National Institute for Health and Care Research","keywords":"mTORC1; PI3K/AKT/mTOR pathway; Autophagy; Lysosome; Mechanistic target of rapamycin; Amino acid; Cell biology; GTPase; Biology; Effector; RPTOR; mTORC2; P70-S6 Kinase 1; Small GTPase; Biochemistry; Kinase; Chemistry; Signal transduction; Enzyme; Apoptosis","retraction":null,"screen_n_in":null,"score":{"opus":0.02267983367522887,"gpt":0.3258171304857511,"spread":0.3031372968105223,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.000719843,0.001173508,0.003501036,0.000231146,0.00006136635,0.00002558177,0.001457197,0.00401041,0.0002036214],"category_scores_gemma":[0.0003472752,0.0008973028,0.002042736,0.0004070669,0.0002648265,0.000004622846,0.0004164049,0.001500594,0.0002215354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008412693,"about_ca_system_score_gemma":0.0004561851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008052707,"about_ca_topic_score_gemma":0.00000196001,"domain_scores_codex":[0.9947603,0.001125248,0.001667559,0.001472988,0.0002241046,0.000749792],"domain_scores_gemma":[0.9961338,0.0000745882,0.00174603,0.001583184,0.0002487291,0.0002136733],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000009274722,0.00008454941,0.000004546303,0.01291647,0.0003509565,0.00001180853,0.000004658558,0.00000193568,0.1601773,0.00008693632,0.003050378,0.8233012],"study_design_scores_gemma":[0.0002001892,0.0003622134,5.338636e-8,0.00328397,0.0007670922,0.00002641198,0.000001438982,8.89872e-7,0.07486726,0.00003277851,0.9197002,0.0007575199],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006624257,0.9931399,0.000927342,0.000009966238,0.0008095112,0.002072784,0.0001498737,0.00002496454,0.002799413],"genre_scores_gemma":[0.0004154183,0.992443,0.003280077,0.000307613,0.0006644236,0.0004751438,0.001775891,0.0001837822,0.000454693],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9166498,"threshold_uncertainty_score":0.9993477,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1968323673","doi":"10.1038/nrm1571","title":"Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling","year":2005,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":861,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Cancer Institute; Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Endocytic cycle; Clathrin; Cell biology; Internalization; Signalling; Endocytosis; Lipid raft; Cell signaling; Signal transducing adaptor protein; Clathrin adaptor proteins; Signal transduction; Cell; Chemistry; Biology; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.01244852792397367,"gpt":0.2744265079985634,"spread":0.2619779800745897,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005895418,0.0008172223,0.002273401,0.0002347755,0.00006330557,0.00001594518,0.0004242136,0.002834539,0.00005437615],"category_scores_gemma":[0.00006661296,0.0006844215,0.001020975,0.0003090684,0.0001697257,0.000005730793,0.0001331198,0.001019177,0.0000380415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004259485,"about_ca_system_score_gemma":0.0002200203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003552028,"about_ca_topic_score_gemma":0.000006299822,"domain_scores_codex":[0.9964395,0.0004476254,0.001364592,0.001098774,0.0001657588,0.0004837389],"domain_scores_gemma":[0.9978181,0.00005542628,0.0010755,0.0007635979,0.0001194812,0.0001678824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002288688,0.0000860162,0.00000897752,0.0110934,0.0001107833,0.00001327462,0.00001463333,0.00000445297,0.6387764,0.00004640144,0.00004004478,0.3497827],"study_design_scores_gemma":[0.000445817,0.0002349159,0.000002238627,0.001633826,0.0007536288,0.00002075679,0.000002186106,0.00001751333,0.01521858,0.00001671914,0.9810475,0.0006063455],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005906264,0.9914227,0.004302396,0.00000599411,0.0002168369,0.001605882,0.00006489453,0.00001518032,0.001775514],"genre_scores_gemma":[0.006286772,0.9767454,0.001461352,0.00009485515,0.0003101232,0.00008122798,0.01471759,0.0001030757,0.0001996671],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9810075,"threshold_uncertainty_score":0.9995607,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3088092039","doi":"10.1038/s41580-020-00288-9","title":"Applications of CRISPR–Cas in agriculture and plant biotechnology","year":2020,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":835,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Genetics","funders":"","keywords":"CRISPR; Genome editing; Biotechnology; Computational biology; Biology; Gene; Computer science; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.0070462557609037,"gpt":0.329453782659948,"spread":0.3224075268990443,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.000191236,0.0005147418,0.001756483,0.0001847526,0.00002131288,0.000006551385,0.0004509267,0.002525938,0.000004799394],"category_scores_gemma":[0.0001009441,0.0003879909,0.0004040071,0.0004629469,0.0001080904,0.000001160333,0.0002878963,0.000973344,0.000009788302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001968702,"about_ca_system_score_gemma":0.00008200845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004666236,"about_ca_topic_score_gemma":0.00001298919,"domain_scores_codex":[0.9978549,0.0002101475,0.0007594459,0.000811665,0.00005990608,0.0003039608],"domain_scores_gemma":[0.998917,0.00002539403,0.0003635397,0.0005684576,0.00003241669,0.00009315421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000003992922,0.00004005599,0.000004762033,0.009234491,0.00007434702,0.00001527033,0.000007334437,0.000001116032,0.03448324,0.0004444012,0.0004827747,0.9552082],"study_design_scores_gemma":[0.0001377409,0.0001218554,6.066694e-7,0.0007610326,0.0002148601,0.00006199673,0.000004081402,0.000001061925,0.01564497,0.00002200877,0.982676,0.0003538406],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000005595448,0.9893827,0.008483029,0.00005160053,0.0000853182,0.001478425,0.0001404586,0.00001351166,0.0003593487],"genre_scores_gemma":[0.0002358215,0.9964582,0.001645661,0.0001081494,0.000110617,0.0003042397,0.001069189,0.00004323902,0.00002493587],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9821932,"threshold_uncertainty_score":0.9998572,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2069508712","doi":"10.1038/nrm858","title":"Protease degradomics: A new challenge for proteomics","year":2002,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Advanced Biosensing Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":755,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"","keywords":"Proteases; Protease; Computational biology; Proteomics; Organism; Biology; Identification (biology); Substrate specificity; Bioinformatics; Biochemistry; Genetics; Enzyme; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.03778487514687382,"gpt":0.3559616989226723,"spread":0.3181768237757984,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003160335,0.0008862463,0.001949558,0.0001255606,0.0001107833,0.0000257694,0.0007714896,0.002961049,0.000009478758],"category_scores_gemma":[0.0002626462,0.000698035,0.001520217,0.0002368896,0.0001074689,0.000002666428,0.000237778,0.0009680327,0.00004432489],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006367287,"about_ca_system_score_gemma":0.0002641265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001968773,"about_ca_topic_score_gemma":0.000002190836,"domain_scores_codex":[0.9967672,0.0002747758,0.0009299258,0.001359972,0.0000786477,0.0005894402],"domain_scores_gemma":[0.9973267,0.00003106555,0.00088265,0.001424052,0.000109899,0.000225581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001040278,0.00008758757,4.213054e-8,0.004969717,0.00006955774,0.000003168924,0.00000184018,1.895183e-7,0.005675895,0.0007354039,0.006956689,0.9814895],"study_design_scores_gemma":[0.0002876702,0.000338942,2.857541e-9,0.001436335,0.0004384786,0.00003061787,4.929916e-7,0.000003567566,0.003172019,0.0006281338,0.9929231,0.0007406247],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[6.120007e-7,0.930259,0.05893738,0.0001069878,0.000143462,0.009557863,0.0001651171,0.00005614985,0.0007734173],"genre_scores_gemma":[0.00000219864,0.8540713,0.1398226,0.0003498902,0.0006022442,0.002189517,0.001975143,0.000147699,0.0008393322],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9859664,"threshold_uncertainty_score":0.9995471,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2071221374","doi":"10.1038/nrm1660","title":"Autophagy in metazoans: cell survival in the land of plenty","year":2005,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":750,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Autophagy; Extracellular; Cell biology; Nutrient; Biology; Cytoplasm; Intracellular; Signal transduction; Essential nutrient; Cell; Catabolism; Biochemistry; Ecology; Metabolism; Apoptosis","retraction":null,"screen_n_in":null,"score":{"opus":0.02999083822462944,"gpt":0.3694382933148463,"spread":0.3394474550902168,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00154908,0.0006328842,0.004098989,0.0003871059,0.00001791869,0.000006538841,0.0006523518,0.001590239,0.0001756038],"category_scores_gemma":[0.0001318044,0.0003505738,0.001283668,0.0008343249,0.000107243,0.00002093355,0.00007342729,0.002186762,0.00007549637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009166788,"about_ca_system_score_gemma":0.0003320848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001982344,"about_ca_topic_score_gemma":0.00001882419,"domain_scores_codex":[0.9950309,0.002205105,0.001422961,0.0006543579,0.0002262421,0.0004604689],"domain_scores_gemma":[0.9978667,0.0002797657,0.0006847858,0.001039177,0.00004240153,0.00008711412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002923468,0.0005951379,0.00005826456,0.0202387,0.0001198694,0.0003738619,0.00004922169,5.396139e-7,0.0001250384,0.0003000962,0.0002005474,0.9779095],"study_design_scores_gemma":[0.0008518058,0.0001385405,0.00003088899,0.003825136,0.0009223655,0.00002668737,0.000004018142,0.000001427671,0.0001355842,0.00005619385,0.9937366,0.0002707999],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001734593,0.9898712,0.0000123614,0.00004652414,0.00023921,0.002719712,0.00005147397,0.0000128851,0.00687319],"genre_scores_gemma":[0.000702171,0.9970789,0.0002267954,0.0009003123,0.0001736487,0.0002225826,0.0005288405,0.00005380937,0.000112956],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.993536,"threshold_uncertainty_score":0.9998946,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2054946171","doi":"10.1038/nrm3979","title":"Regulation of RAF protein kinases in ERK signalling","year":2015,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":702,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université du Québec à Montréal; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Kinase; Allosteric regulation; MAPK/ERK pathway; Signalling; Cell biology; Function (biology); Suppressor; Phosphorylation; Chemistry; Biology; Biochemistry; Enzyme; Cancer; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.02828340218594011,"gpt":0.317174288496513,"spread":0.2888908863105729,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00109836,0.0006258423,0.00234116,0.0002493307,0.00002323381,0.00000914787,0.0005600764,0.002498543,0.00002233143],"category_scores_gemma":[0.0003332285,0.0004897008,0.0007593574,0.0003922363,0.00009632801,0.000003031423,0.0002078424,0.0007894658,0.00003364235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000507836,"about_ca_system_score_gemma":0.0004192099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008360352,"about_ca_topic_score_gemma":0.000009614839,"domain_scores_codex":[0.9961216,0.001217004,0.001228489,0.0008756322,0.000149826,0.0004074149],"domain_scores_gemma":[0.9978906,0.00002519943,0.001005719,0.000815851,0.0001468934,0.0001157641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002417453,0.000102682,0.000003128303,0.01461717,0.00006693138,0.00002095577,0.000006726089,0.000003219084,0.2511881,0.0004406501,0.0007114283,0.7328148],"study_design_scores_gemma":[0.0002625528,0.0002896339,3.909991e-7,0.003937528,0.0001914929,0.00001111371,0.00000148841,0.000001332055,0.01847644,0.0001416935,0.97624,0.0004462765],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002136944,0.9937434,0.000327297,0.000006064539,0.0002116143,0.002365679,0.00006223233,0.000009802789,0.003060278],"genre_scores_gemma":[0.0009561759,0.9942365,0.001407898,0.00005752017,0.0002185183,0.0002891647,0.002499426,0.00007125144,0.0002634893],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9755286,"threshold_uncertainty_score":0.9997554,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2048839385","doi":"10.1038/nrm2208","title":"Analysis of protein complexes using mass spectrometry","year":2007,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":698,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University Health Network; University of Toronto; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute","funders":"National Heart, Lung, and Blood Institute","keywords":"Mass spectrometry; Chemistry; Proteomics; Supramolecular chemistry; Fractionation; Protein–protein interaction; Characterization (materials science); Chromatography; Computational biology; Biochemistry; Nanotechnology; Molecule; Biology; Materials science; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.03775440111769055,"gpt":0.3855465297747507,"spread":0.3477921286570602,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0004475604,0.000621183,0.003973683,0.0006865535,0.00005340901,0.00001020088,0.0007857505,0.002010878,0.0003082422],"category_scores_gemma":[0.0000772988,0.0004957434,0.002088466,0.002294114,0.0001361395,0.00001649699,0.0001511425,0.001690642,0.00001101308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000179859,"about_ca_system_score_gemma":0.00009425603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007106391,"about_ca_topic_score_gemma":0.000001031868,"domain_scores_codex":[0.9970936,0.0001581828,0.001391691,0.0008091615,0.0001322969,0.0004150394],"domain_scores_gemma":[0.9966944,0.0000867909,0.001768493,0.001267606,0.00009172554,0.00009094222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000003160454,0.00007933591,0.000003896047,0.02622585,0.001035936,0.00001282284,0.000001770422,0.000002494728,0.2463427,0.003794282,0.00001046472,0.7224873],"study_design_scores_gemma":[0.00004211666,0.00001326607,1.410053e-8,0.002449919,0.004617583,0.000004622545,7.230665e-7,0.0000137857,0.02469283,0.0004079,0.967338,0.0004192721],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001062592,0.9024621,0.09132912,0.000002332241,0.00001694898,0.001120076,0.0002205475,0.00004961207,0.004788643],"genre_scores_gemma":[0.00001674086,0.8215581,0.1770129,0.00002848347,0.00005538241,0.0001838169,0.001003747,0.00005772318,0.00008305991],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9673275,"threshold_uncertainty_score":0.9997494,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2269834552","doi":"10.1038/nrm.2015.16","title":"Mechanisms of ephrin–Eph signalling in development, physiology and disease","year":2016,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":686,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Erythropoietin-producing hepatocellular (Eph) receptor; Ephrin; Cell biology; Signalling; Biology; EPH receptor A2; Neuroscience; Morphogenesis; Signal transduction; Receptor tyrosine kinase; Genetics; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.03986926506445417,"gpt":0.3246717064312903,"spread":0.2848024413668361,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005167199,0.0006317407,0.002467686,0.0003180604,0.00005804621,0.000008271961,0.0006277485,0.0008610938,0.00006080115],"category_scores_gemma":[0.0007876941,0.0004138555,0.0004449984,0.000416919,0.0001687874,0.00004474014,0.0003024593,0.0009985339,0.00007878769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005159152,"about_ca_system_score_gemma":0.0003340484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":4.562338e-7,"about_ca_topic_score_gemma":3.954247e-7,"domain_scores_codex":[0.9954457,0.001441509,0.001231178,0.001208815,0.0001459618,0.0005268225],"domain_scores_gemma":[0.9978815,0.0005102884,0.0009480897,0.0004243337,0.0000284885,0.0002073298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001483211,0.00004828597,6.937539e-7,0.01191038,0.00001107593,0.00009286163,0.000005368561,2.703829e-7,0.3547634,0.00369942,0.00001126314,0.6294422],"study_design_scores_gemma":[0.000174053,0.00004723581,5.737206e-7,0.008224038,0.00009247362,0.00001126698,2.999556e-7,0.000001012504,0.0303216,0.002157551,0.958544,0.0004258911],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008068878,0.9969915,0.001127954,0.00001564477,0.0002010439,0.001182868,0.00002861475,0.00001988043,0.000351863],"genre_scores_gemma":[0.001955067,0.9963896,0.0005442402,0.0007866065,0.00003906383,0.0001597493,0.00002521151,0.0000568767,0.0000436076],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9585328,"threshold_uncertainty_score":0.9998313,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1988805210","doi":"10.1038/nrm1960","title":"Reading protein modifications with interaction domains","year":2006,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":666,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Posttranslational modification; Proteome; Computational biology; Protein–protein interaction; Reading (process); Cell biology; Computer science; Biology; Chemistry; Bioinformatics; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.02166225441878624,"gpt":0.3182832856933068,"spread":0.2966210312745206,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0004683392,0.0008063841,0.001603632,0.0002027098,0.000127123,0.00004374601,0.0005928305,0.002105053,0.0000259259],"category_scores_gemma":[0.0001122588,0.0005732894,0.0007733078,0.0003858023,0.0001267356,0.000004977631,0.0001577629,0.001357052,0.0001326617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007885701,"about_ca_system_score_gemma":0.0002558503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008801355,"about_ca_topic_score_gemma":0.000007730365,"domain_scores_codex":[0.9963844,0.0009613103,0.0008422371,0.001168708,0.0001276974,0.0005156275],"domain_scores_gemma":[0.9976504,0.00002610575,0.0009102055,0.001171222,0.000114075,0.0001280338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002554294,0.0001479488,0.000001286751,0.01072292,0.0001987631,0.00002958764,0.00000550691,0.000002303469,0.06014893,0.001555992,0.002151033,0.9250102],"study_design_scores_gemma":[0.0001848819,0.0002677742,6.812487e-8,0.003007951,0.0003952756,0.00007425428,0.000001780239,8.991875e-7,0.01041923,0.00003682988,0.9849629,0.0006481636],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002988729,0.9738802,0.002295049,0.00002026169,0.0001726133,0.003281608,0.0001022339,0.00003630529,0.02018181],"genre_scores_gemma":[0.0002012121,0.9882472,0.003809103,0.0001590801,0.0004075021,0.001402109,0.004472259,0.0001271395,0.001174416],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9828119,"threshold_uncertainty_score":0.9996719,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2964804212","doi":"10.1038/s41580-019-0155-x","title":"The regulation, functions and clinical relevance of arginine methylation","year":2019,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":642,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Protein arginine methyltransferase 5; Methylation; Methyltransferase; Arginine; Biology; DNA methylation; Signal transduction; DNA damage; Biochemistry; Gene expression; Cell biology; DNA; Computational biology; Gene; Amino acid","retraction":null,"screen_n_in":null,"score":{"opus":0.02251786880701185,"gpt":0.3554834264855082,"spread":0.3329655576784963,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.001344587,0.0004627515,0.00153202,0.00009986653,0.0001026605,0.00001601478,0.0003452034,0.00227151,0.00001013655],"category_scores_gemma":[0.0007783404,0.0003105247,0.0008777718,0.0003592051,0.0002708971,0.000004176939,0.0001812269,0.0008832983,0.00003349595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003931876,"about_ca_system_score_gemma":0.0002701055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002239587,"about_ca_topic_score_gemma":0.00001146342,"domain_scores_codex":[0.9959733,0.001303426,0.001463314,0.0008533147,0.0001277138,0.000278931],"domain_scores_gemma":[0.996734,0.0002659598,0.001545273,0.001167525,0.0002117822,0.00007549528],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001836159,0.00002065458,0.000009164675,0.002090664,0.0001978558,2.153623e-7,0.000001203452,0.000008275773,0.002478221,0.000270707,0.001893485,0.9930112],"study_design_scores_gemma":[0.0002315042,0.0002221535,0.0000103839,0.0009049035,0.0009154788,0.00001265927,0.000001155271,0.00001481136,0.000307808,0.00006553526,0.9970223,0.0002912868],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003979265,0.9945899,0.001470395,0.00006373127,0.001087931,0.001735458,0.00004096958,0.000009969515,0.00096185],"genre_scores_gemma":[0.0001673028,0.9956232,0.0004472961,0.00004970495,0.0004017411,0.00008206319,0.001476746,0.00006087312,0.001691085],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9951288,"threshold_uncertainty_score":0.9999347,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2065547075","doi":"10.1038/35096067","title":"PKB/AKT: functional insights from genetic models","year":2001,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":611,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Cancer Institute; Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Protein kinase B; Computational biology; Proto-Oncogene Proteins c-akt; Relevance (law); Biology; PI3K/AKT/mTOR pathway; Cell biology; Signal transduction; Political science","retraction":null,"screen_n_in":null,"score":{"opus":0.03115802875329576,"gpt":0.307269794107975,"spread":0.2761117653546792,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0002921177,0.001450155,0.003054506,0.0002565745,0.0001328592,0.00005013778,0.001302143,0.005036816,0.0002428398],"category_scores_gemma":[0.0001580393,0.001161117,0.001985383,0.0005712639,0.0002271187,0.000007340529,0.0004888383,0.001985644,0.0003715116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001632893,"about_ca_system_score_gemma":0.0006376298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001839866,"about_ca_topic_score_gemma":0.00001235166,"domain_scores_codex":[0.9937052,0.001336301,0.001535287,0.002304386,0.0003147594,0.0008041099],"domain_scores_gemma":[0.9962862,0.00008804461,0.001093802,0.002017842,0.0002090693,0.0003050356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003495978,0.0001465646,0.000003438312,0.00369417,0.0006800339,0.0001113466,0.000006272356,0.0001209735,0.01627423,0.0003306488,0.007653303,0.970944],"study_design_scores_gemma":[0.000370206,0.0002169289,4.366239e-7,0.001933653,0.001059438,0.00004954638,7.69215e-7,0.00001885018,0.001213662,0.0006831664,0.9932699,0.001183436],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006220357,0.9820491,0.008733717,0.00001497839,0.001792989,0.001676941,0.0002445296,0.00004716827,0.005378344],"genre_scores_gemma":[0.0001989307,0.9853035,0.002862474,0.001223499,0.001948279,0.0005350777,0.006975044,0.0002373761,0.0007158677],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9856166,"threshold_uncertainty_score":0.9998248,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2279554517","doi":"10.1038/nrm.2015.27","title":"Pluripotent stem cells in disease modelling and drug discovery","year":2016,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":596,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; Rosetrees Trust; New York Stem Cell Foundation","keywords":"Induced pluripotent stem cell; Drug discovery; Embryonic stem cell; Stem cell; Biology; Epigenetics; Disease; Computational biology; Neuroscience; Drug development; Human disease; Human Induced Pluripotent Stem Cells; Drug; Bioinformatics; Medicine; Cell biology; Genetics; Pharmacology; Gene; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.01983649628657849,"gpt":0.3013654564288228,"spread":0.2815289601422443,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.001116655,0.001097391,0.002475669,0.0003796568,0.0000769111,0.00007180681,0.0009734753,0.001689536,0.00001210584],"category_scores_gemma":[0.00005568134,0.0007504747,0.001057279,0.0003287313,0.0002308645,0.00001288789,0.0008978323,0.00139962,0.0001206571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001239896,"about_ca_system_score_gemma":0.0004255804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006667579,"about_ca_topic_score_gemma":0.000005238849,"domain_scores_codex":[0.9935514,0.001859092,0.001271275,0.002053653,0.0002629881,0.00100153],"domain_scores_gemma":[0.9973637,0.000100027,0.0005958233,0.001440488,0.00007476499,0.0004252065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007031648,0.0001779396,0.00001192818,0.02796742,0.0001801137,0.0002789451,0.00001011458,0.00004048318,0.01264295,0.0001696612,0.0007955153,0.9576546],"study_design_scores_gemma":[0.0003679358,0.00006670584,1.310208e-7,0.006466691,0.0002264361,0.00001396436,0.000001768848,0.00001759054,0.001276104,0.00005155373,0.9906806,0.000830468],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002007142,0.9937247,0.002215101,0.00005225819,0.0003895991,0.002675292,0.0002867356,0.00001535261,0.0004402192],"genre_scores_gemma":[0.0003401428,0.9955832,0.000307208,0.0001896888,0.0002434934,0.0003744812,0.0005706375,0.0001542218,0.002236906],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9898852,"threshold_uncertainty_score":0.9996065,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2799809717","doi":"10.1038/s41580-018-0009-y","title":"Microtubule dynamics: an interplay of biochemistry and mechanics","year":2018,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":581,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences","keywords":"Microtubule; Tubulin; Biophysics; Organelle; Dimer; Chemistry; Biology; Cell biology","retraction":null,"screen_n_in":null,"score":{"opus":0.007950142012270397,"gpt":0.3029865981971508,"spread":0.2950364561848804,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005999586,0.0009018568,0.0023104,0.0001646271,0.00005846815,0.00002429709,0.0009455928,0.003650314,0.0000264399],"category_scores_gemma":[0.0001632432,0.0007409746,0.0008780889,0.0001860702,0.0002427407,0.000004408035,0.000597535,0.0009272122,0.00002081359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006027601,"about_ca_system_score_gemma":0.0002627621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008024242,"about_ca_topic_score_gemma":0.00003628764,"domain_scores_codex":[0.9962861,0.0005822276,0.001149628,0.001383277,0.00009581185,0.0005029631],"domain_scores_gemma":[0.997093,0.00002625722,0.00101383,0.001499476,0.0001668206,0.0002006284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002496394,0.0001896128,0.000002900196,0.02424229,0.0003621225,0.00001158423,0.00001129163,1.12183e-7,0.1991084,0.0005045432,0.001410537,0.7741317],"study_design_scores_gemma":[0.0001911621,0.0004653734,2.190824e-8,0.002310083,0.0006355137,0.00009792979,0.000005112332,0.00001648117,0.02327528,0.00005737653,0.9722629,0.0006827384],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002466444,0.9953082,0.001917339,0.000006541778,0.0003520904,0.001148679,0.000384631,0.00001473619,0.0006211037],"genre_scores_gemma":[0.0002246919,0.9907762,0.002877386,0.0002277557,0.0002724246,0.00009979671,0.005176317,0.0001268883,0.0002185426],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9708524,"threshold_uncertainty_score":0.9995041,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1986960362","doi":"10.1038/nrm3567","title":"Molecular mechanisms underlying RB protein function","year":2013,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":561,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Children’s Health Research Institute; Western University","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Suppressor; Cell cycle; Biology; Cell biology; E2F; Transcription factor; Apoptosis; Function (biology); Cancer cell; E2F1; Cancer; Computational biology; Gene; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.04209877753200075,"gpt":0.3362592901221411,"spread":0.2941605125901403,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.000943662,0.001778179,0.005766131,0.0007705942,0.0001308125,0.00006405675,0.0006902005,0.006678458,0.0004489121],"category_scores_gemma":[0.0004402371,0.001369881,0.003175128,0.001314039,0.0001571101,0.00006661755,0.0003218422,0.006031299,0.001961327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006729938,"about_ca_system_score_gemma":0.0008767716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001399085,"about_ca_topic_score_gemma":0.000001792204,"domain_scores_codex":[0.9924459,0.001759257,0.00198848,0.002114864,0.000512376,0.001179143],"domain_scores_gemma":[0.9952899,0.00007166086,0.001544789,0.002287024,0.0002887855,0.0005179066],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001721707,0.0001596878,2.762683e-8,0.0298153,0.00053081,0.0003443392,0.000004701481,7.70654e-7,0.07271535,0.005550785,0.0006775676,0.8901834],"study_design_scores_gemma":[0.0006926045,0.0007865963,4.988516e-8,0.01814672,0.00483738,0.0002972155,0.000003062264,0.000006627544,0.00236859,0.001210348,0.9705455,0.001105302],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000006090556,0.9410636,0.03738217,0.00008126005,0.001129565,0.01309427,0.00003336351,0.0002366894,0.006972963],"genre_scores_gemma":[0.00007926782,0.9861584,0.006831232,0.001394065,0.0001495051,0.002630592,0.001771243,0.0004167681,0.0005688799],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9698679,"threshold_uncertainty_score":0.9994964,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4394581121","doi":"10.1038/s41580-024-00716-0","title":"Fibroblast and myofibroblast activation in normal tissue repair and fibrosis","year":2024,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":561,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; University of Toronto; St. Michael's Hospital","funders":"","keywords":"Myofibroblast; Cell biology; Fibroblast; Extracellular matrix; Fibrosis; Mesenchymal stem cell; Stromal cell; Progenitor cell; Biology; Cancer research; Stem cell; Pathology; Medicine; Cell culture; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.02535454827364192,"gpt":0.3722945857590068,"spread":0.3469400374853649,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0009287603,0.0007765593,0.003128199,0.0007091222,0.00004847249,0.00004412702,0.0001939926,0.002305271,0.00009647541],"category_scores_gemma":[0.0004244876,0.0005321063,0.0005014967,0.0009538109,0.000189443,0.00005718442,0.0004408557,0.002916128,0.0001810782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000183696,"about_ca_system_score_gemma":0.0002587778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002370439,"about_ca_topic_score_gemma":0.000008331178,"domain_scores_codex":[0.9958624,0.0008765706,0.001099804,0.001303782,0.0002433795,0.0006140521],"domain_scores_gemma":[0.9984139,0.0002488812,0.0003077901,0.0006676098,0.00006725,0.0002946353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002557224,0.00004134707,0.0000121906,0.1589345,0.000096604,0.0001578773,0.0000204507,3.369925e-8,0.006105423,0.0002006772,0.00138131,0.833024],"study_design_scores_gemma":[0.0002516832,0.0004496989,0.000004969587,0.04998674,0.0005478081,0.0001736155,0.00000299498,0.000006979456,0.0005516765,0.00002435536,0.9476137,0.0003857366],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008654125,0.9913263,0.000032461,0.0001065437,0.00008940513,0.003378012,0.00002265062,0.00006561098,0.004892469],"genre_scores_gemma":[0.0001271064,0.9959663,0.001598427,0.0001429454,0.0001651256,0.0002372658,0.0004077842,0.0001058037,0.001249289],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9462324,"threshold_uncertainty_score":0.9997131,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1998068719","doi":"10.1038/nrm3249","title":"Canonical and non-canonical autophagy: variations on a common theme of self-eating?","year":2011,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":532,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Institut National Du Cancer; Institute of Cancer Research; Institut National de la Santé et de la Recherche Médicale; Université Paris-Sud; Agence Nationale de la Recherche","keywords":"Non canonical; Autophagy; Canonical correspondence analysis; Canonical correlation; Canonical analysis; Theme (computing); Chemistry; Biology; Psychology; Mathematics; Biochemistry; Cell biology; Ecology; Computer science; Statistics; World Wide Web","retraction":null,"screen_n_in":null,"score":{"opus":0.02222160157914055,"gpt":0.3488216784045386,"spread":0.3266000768253981,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005294441,0.0006821314,0.004018491,0.0002180346,0.00006139375,0.000007733292,0.00036547,0.002124712,0.0001860279],"category_scores_gemma":[0.0001619445,0.00044733,0.001139846,0.0003540205,0.0001641927,0.00001594873,0.0001369445,0.001917932,0.00008058457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009826946,"about_ca_system_score_gemma":0.0007874173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001478351,"about_ca_topic_score_gemma":0.000002117076,"domain_scores_codex":[0.9966298,0.000829923,0.00121617,0.0007711545,0.0001505857,0.0004023954],"domain_scores_gemma":[0.9974164,0.0002751066,0.0008723587,0.001091025,0.00008048583,0.0002645637],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005680971,0.0009377152,0.0000321246,0.02601543,0.0009738605,0.0001632037,0.00006352033,2.890908e-8,0.0002632112,0.01279758,0.0004994517,0.9581971],"study_design_scores_gemma":[0.0006080724,0.0007130282,0.00002941854,0.007167243,0.002809529,0.00006866934,6.558896e-7,0.000004320258,0.000138302,0.0002305758,0.9878895,0.0003406418],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001256004,0.9847876,0.00004854754,0.0000247065,0.0002144292,0.002328388,0.0000645508,0.00004681462,0.01235935],"genre_scores_gemma":[0.001417627,0.994862,0.001758811,0.001036399,0.000155779,0.0002184017,0.0003601938,0.00008033119,0.0001104467],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9873901,"threshold_uncertainty_score":0.9997978,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2019101092","doi":"10.1038/nrm3265","title":"Satellite cells, the engines of muscle repair","year":2011,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":503,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Myogenesis; Satellite; PAX3; Cell biology; Progenitor cell; Embryonic stem cell; Regeneration (biology); Skeletal muscle; Biology; Population; Stem cell; Progenitor; Myocyte; Transcription factor; Anatomy; Genetics; Gene; Engineering; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.01674645662765726,"gpt":0.2896464249075797,"spread":0.2728999682799225,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006635871,0.0007544766,0.001988138,0.0001104221,0.00007730856,0.000005676091,0.001047863,0.002485786,0.00006343218],"category_scores_gemma":[0.0001713999,0.0004553446,0.002150099,0.0003115259,0.0003670062,0.000002377614,0.0003534322,0.001059495,0.00008748157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001197181,"about_ca_system_score_gemma":0.0001888518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008507714,"about_ca_topic_score_gemma":0.000006082392,"domain_scores_codex":[0.9961275,0.001324678,0.0010163,0.0009627446,0.00007665592,0.0004920727],"domain_scores_gemma":[0.9971375,0.00007099177,0.0008791922,0.001715478,0.0001009916,0.00009579691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002080175,0.0001213995,0.000001836597,0.01008672,0.0002923236,0.000004788443,0.00001660514,5.550228e-7,0.01674469,0.000881998,0.00290687,0.9689214],"study_design_scores_gemma":[0.0001247787,0.0002263763,0.000001379124,0.0007109195,0.0006074334,0.000006758336,0.000002940583,2.698436e-7,0.002479851,0.0001169659,0.9952682,0.0004541308],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003236371,0.9919019,0.00009186634,0.000009071961,0.0005854756,0.001335826,0.00005594708,0.00002459067,0.005962955],"genre_scores_gemma":[0.0001998702,0.9972263,0.0005423884,0.0004420082,0.0002134042,0.000188749,0.0008519623,0.00008102265,0.000254326],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9923613,"threshold_uncertainty_score":0.9997898,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1575878259","doi":"10.1038/35040042","title":"Cadherins in embryonic and neural morphogenesis","year":2000,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":490,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Toronto Zoo; Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"Cadherin; Morphogenesis; Neurite; Cell biology; Biology; Neuroscience; Embryonic stem cell; Neural cell; Cell; Protocadherin; Nervous system; Genetics; Gene; In vitro","retraction":null,"screen_n_in":null,"score":{"opus":0.04586658588132207,"gpt":0.3410036509987014,"spread":0.2951370651173793,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003393839,0.0007427962,0.002541613,0.0002959824,0.00007362113,0.00002941361,0.0006686742,0.001331424,0.000109067],"category_scores_gemma":[0.0002209637,0.0005543923,0.0006452498,0.0007870407,0.0001494213,0.0000493667,0.0001788231,0.001970736,0.0001671442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006661033,"about_ca_system_score_gemma":0.0001202579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004938767,"about_ca_topic_score_gemma":0.000003617817,"domain_scores_codex":[0.9952274,0.001722693,0.0008952773,0.001378527,0.0001411691,0.0006349537],"domain_scores_gemma":[0.9985396,0.0002780186,0.0004510928,0.0005794368,0.00001066343,0.0001411994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005707311,0.00002943389,0.000001438616,0.004311406,0.000004753663,0.0003128187,0.000003026135,0.000001132604,0.007266772,0.0001017617,0.00007500047,0.9878867],"study_design_scores_gemma":[0.0001348498,0.00008690276,3.570054e-7,0.001990536,0.0001469778,0.0001488642,2.762474e-7,0.000007554599,0.0008690404,0.00002601904,0.9961054,0.0004831801],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002590693,0.9961941,0.000005656967,0.00003371048,0.0002626848,0.00134837,0.00003277445,0.00003523672,0.001828445],"genre_scores_gemma":[0.0002539921,0.9973305,0.00005760455,0.00177642,0.00009261527,0.0001700595,0.00002911275,0.00007935431,0.0002103657],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9960304,"threshold_uncertainty_score":0.9999651,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2037215281","doi":"10.1038/nrm3915","title":"Non-histone protein methylation as a regulator of cellular signalling and function","year":2014,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":475,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Histone methylation; Cell biology; Biology; Histone methyltransferase; Histone code; Histone; Epigenomics; Chromatin remodeling; Crosstalk; DNA methylation; Genetics; Nucleosome; Gene expression; DNA; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.009136434105716098,"gpt":0.295227837572184,"spread":0.2860914034664679,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0009654162,0.0007238982,0.002188266,0.000266797,0.00007238046,0.00001559709,0.0003121578,0.003166368,0.00002520141],"category_scores_gemma":[0.0001784406,0.000622533,0.0008463263,0.0003831662,0.0001622983,0.000005287735,0.000168847,0.0008039041,0.00003003341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007555394,"about_ca_system_score_gemma":0.000261636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009773105,"about_ca_topic_score_gemma":0.000003571956,"domain_scores_codex":[0.9962756,0.0007997526,0.001243152,0.001137851,0.0001799495,0.0003636768],"domain_scores_gemma":[0.9972131,0.00002884631,0.001588183,0.0008580675,0.0001809703,0.000130785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002747594,0.00002447747,3.79181e-7,0.008560771,0.0001412731,0.000001206318,0.000003484722,0.000007606759,0.461497,0.000159391,0.0001235022,0.5294534],"study_design_scores_gemma":[0.0002892882,0.0004854128,3.141923e-7,0.002771531,0.0009491578,0.00001276525,8.897187e-7,0.00002350877,0.08029555,0.0001253086,0.9145336,0.0005126579],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005834545,0.980742,0.01491618,0.00001237621,0.0003421048,0.002727037,0.00001716554,0.00001543073,0.000644224],"genre_scores_gemma":[0.003691084,0.9921191,0.001062767,0.00006442091,0.0004139552,0.0002587293,0.001849818,0.0001148931,0.0004252548],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9144101,"threshold_uncertainty_score":0.9996226,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2070582215","doi":"10.1038/nrm2651","title":"The emerging role of nuclear architecture in DNA repair and genome maintenance","year":2009,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":463,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Institute of Genetics; National Cancer Institute; National Institutes of Health; Centre National de la Recherche Scientifique","keywords":"Chromatin; DNA repair; Genome; Biology; Computational biology; DNA damage; DNA; Genome instability; Genetics; Cell biology; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.005714917650166134,"gpt":0.2625691240664471,"spread":0.2568542064162809,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0009978701,0.0006526161,0.001814206,0.0001485477,0.0000757396,0.00001498922,0.0007624684,0.001705237,0.000005861116],"category_scores_gemma":[0.0003059878,0.0004206483,0.000987442,0.0003138703,0.0001837925,0.000002091095,0.0003761279,0.001206259,0.000009186531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003819389,"about_ca_system_score_gemma":0.0001142704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003205127,"about_ca_topic_score_gemma":0.00001390898,"domain_scores_codex":[0.9962869,0.001010336,0.001016268,0.0009997975,0.0001163984,0.0005702522],"domain_scores_gemma":[0.9978498,0.00004689418,0.0007421157,0.001201969,0.00005904291,0.0001002385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000177104,0.00003708077,7.749929e-7,0.003032889,0.0000941282,0.00001940417,0.00001523017,0.000001392507,0.06810838,0.0009798913,0.0001199733,0.9275731],"study_design_scores_gemma":[0.0001482656,0.0002317446,0.00000113516,0.001439318,0.0001792091,0.00006114633,0.000007608937,0.000002366998,0.0005919593,0.0003605196,0.9965773,0.0003994357],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001380949,0.9963144,0.0000527045,0.00004047664,0.000121255,0.001411651,0.00002632896,0.00002084234,0.001874226],"genre_scores_gemma":[0.0001909451,0.9968284,0.002081222,0.0003243596,0.0001041033,0.00007449863,0.0001934323,0.00008202739,0.0001209898],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9964573,"threshold_uncertainty_score":0.9998245,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2962922400","doi":"10.1038/s41580-019-0158-7","title":"Extracellular vesicles: a new communication paradigm?","year":2019,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":455,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Ligue Contre le Cancer; Fondation pour la Recherche Médicale; Institut national de la recherche scientifique","keywords":"Extracellular vesicles; Extracellular; Vesicle; Cell biology; Extracellular vesicle; Signalling; Microvesicles; Biology; Chemistry; Biochemistry; microRNA; Membrane","retraction":null,"screen_n_in":null,"score":{"opus":0.02751543604100611,"gpt":0.3344127050852124,"spread":0.3068972690442063,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0009432478,0.001307026,0.002941814,0.0002268133,0.0001123408,0.00007257819,0.002331561,0.003933106,0.0001204923],"category_scores_gemma":[0.0003988731,0.001122236,0.002215626,0.0004765321,0.0002299664,0.000008786315,0.0007361007,0.002022879,0.001235185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001051794,"about_ca_system_score_gemma":0.0008874533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006232495,"about_ca_topic_score_gemma":0.000002811,"domain_scores_codex":[0.993355,0.002168737,0.00163277,0.001760268,0.0002335729,0.0008496831],"domain_scores_gemma":[0.993678,0.0001005956,0.00141306,0.004290545,0.0000807531,0.0004370168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001831848,0.0001626909,0.000002692639,0.01162881,0.000282246,0.00003599042,0.000009859104,0.000002249711,0.01228652,0.002106954,0.01103743,0.9624262],"study_design_scores_gemma":[0.0004081607,0.0001738866,1.436684e-7,0.002952065,0.001486675,0.00005354145,0.000002319917,0.000002548767,0.001190792,0.000305555,0.9923125,0.001111801],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001221196,0.990946,0.002185215,0.00004869997,0.0005059862,0.003264552,0.0000788536,0.00004900591,0.002909507],"genre_scores_gemma":[0.00006367856,0.9854112,0.003926149,0.0003972072,0.0004414085,0.0002312093,0.005474342,0.0002615699,0.003793252],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9812751,"threshold_uncertainty_score":0.9999681,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2587723625","doi":"10.1038/nrm.2016.162","title":"Mitotic spindle assembly in animal cells: a fine balancing act","year":2017,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":450,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Sinai Health System; Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Centrosome; Spindle apparatus; Cell biology; Spindle pole body; Mitosis; Microtubule organizing center; Biology; Microtubule nucleation; Microtubule; Kinetochore; Multipolar spindles; Chromosome segregation; Chromatin; Spindle checkpoint; Astral microtubules; Cell division; Cell cycle; Genetics; Cell; Chromosome; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.02205888712570176,"gpt":0.3346968738136168,"spread":0.312637986687915,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008676274,0.001111817,0.003231958,0.000280844,0.0001107428,0.00006691098,0.001482634,0.00389571,0.00002413916],"category_scores_gemma":[0.0003537025,0.000907619,0.001534793,0.0002391427,0.0001249685,0.000006346033,0.0005733626,0.001931467,0.0001637112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001050602,"about_ca_system_score_gemma":0.0005018129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002049241,"about_ca_topic_score_gemma":0.0001139305,"domain_scores_codex":[0.9951913,0.0009081477,0.001285891,0.001580611,0.0001333025,0.0009007666],"domain_scores_gemma":[0.9965555,0.00004029521,0.001204914,0.001938312,0.00007994629,0.0001810327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000199959,0.0001626029,0.00001603826,0.01218234,0.0001638048,0.0001327562,0.000005191829,0.000001005336,0.1427505,0.00005630358,0.001774251,0.8427352],"study_design_scores_gemma":[0.0003479444,0.000292308,0.000001502319,0.003936625,0.0004207011,0.00005608529,9.526589e-7,0.000004489775,0.005436364,0.000006404675,0.9886157,0.000880945],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002629477,0.9940633,0.0001561854,0.00002130999,0.0007123643,0.001877833,0.00008395551,0.00001623714,0.002805865],"genre_scores_gemma":[0.0006263522,0.9949968,0.001035802,0.0002691316,0.0004942248,0.0002213301,0.001759643,0.0001467305,0.0004499437],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9868414,"threshold_uncertainty_score":0.9993374,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3205354997","doi":"10.1038/s41580-021-00421-2","title":"Control of satellite cell function in muscle regeneration and its disruption in ageing","year":2021,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":448,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Regeneration (biology); Cell biology; Stem cell; Biology; Skeletal muscle; Myocyte; Population; Satellite; Cell; Cellular differentiation; Neuroscience; Anatomy; Genetics; Medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.01235735639270097,"gpt":0.291972402620737,"spread":0.279615046228036,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005633928,0.0004221546,0.001541594,0.000199287,0.00002613741,0.000007444091,0.0001681653,0.001846118,0.00001210373],"category_scores_gemma":[0.0001576208,0.0003679573,0.0003841739,0.0003193917,0.00005548655,0.000005558446,0.00009223642,0.0006907525,0.00000534565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002576391,"about_ca_system_score_gemma":0.0001158299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007985546,"about_ca_topic_score_gemma":0.00005193643,"domain_scores_codex":[0.9965541,0.001429149,0.0008593944,0.0008026593,0.00005981976,0.0002948677],"domain_scores_gemma":[0.9989246,0.00004256874,0.0005212397,0.0003999408,0.00005966352,0.00005200189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003409002,0.0001190894,0.00002846611,0.008013722,0.00003540079,0.00001648541,0.000008818871,0.00001343491,0.1916302,0.0002741094,0.00002135394,0.7998049],"study_design_scores_gemma":[0.0006258046,0.0002008568,0.00003841112,0.001565067,0.0001945851,0.000003754184,0.000004483553,0.00001144102,0.002351632,0.00004379058,0.9946073,0.0003528651],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002376452,0.9954518,0.0004252712,0.00001194047,0.0002001103,0.001057164,0.00002141368,0.000003955139,0.0004518725],"genre_scores_gemma":[0.05217365,0.9456698,0.00007270106,0.0001901326,0.00007342236,0.0001346795,0.001623675,0.00003266663,0.00002926793],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9945859,"threshold_uncertainty_score":0.9998772,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2037606715","doi":"10.1038/nrm2854","title":"Repeat instability as the basis for human diseases and as a potential target for therapy","year":2010,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":431,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"National Institute of Neurological Disorders and Stroke; Muscular Dystrophy Canada; National Institutes of Health; University of Rochester; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Pathogenesis; Epigenetics; Disease; Biology; Genome instability; DNA; Trinucleotide repeat expansion; Transcription (linguistics); DNA methylation; Genetics; Bioinformatics; Neuroscience; Medicine; DNA damage; Gene; Immunology; Gene expression; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.03504752321665539,"gpt":0.3596660601247794,"spread":0.324618536908124,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005394148,0.0008705938,0.002127479,0.0001238287,0.0004628214,0.000094407,0.001030889,0.001013417,0.00007043927],"category_scores_gemma":[0.004227568,0.0004995547,0.001770938,0.0002706216,0.0005167085,0.00003464366,0.0002190636,0.001032316,0.00001916543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003492569,"about_ca_system_score_gemma":0.0003313062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003198076,"about_ca_topic_score_gemma":0.000001668969,"domain_scores_codex":[0.9942462,0.002259663,0.0008746668,0.001861227,0.0001810177,0.000577167],"domain_scores_gemma":[0.9965714,0.0009244295,0.0007535284,0.001390042,0.0001371088,0.0002234545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005052516,0.0002201901,0.00000245813,0.006825396,0.00003921992,0.00001177238,0.00001099976,2.812872e-7,0.08204351,0.002585021,0.0004310159,0.9077796],"study_design_scores_gemma":[0.0003357687,0.0004907379,0.000001162002,0.0003499723,0.0006268702,0.00002301487,0.00000124495,0.000001266263,0.02224859,0.002784949,0.9726593,0.0004771389],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001012583,0.9856548,0.0002581378,0.0001685585,0.0007047103,0.01081481,0.001123383,0.00004110941,0.000221881],"genre_scores_gemma":[0.000879468,0.9911596,0.0005238499,0.002846733,0.0003010667,0.003694206,0.0003566357,0.0001113662,0.0001270358],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9722283,"threshold_uncertainty_score":0.9997456,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2012502527","doi":"10.1038/nrm879","title":"Life at the edge: the nuclear envelope and human disease","year":2002,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":423,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Lamin; Nuclear lamina; Biology; Envelope (radar); Housekeeping gene; Gene; Genetics; Nuclear protein; Nucleus; Cell biology; Computational biology; Gene expression; Transcription factor","retraction":null,"screen_n_in":null,"score":{"opus":0.01475756050491338,"gpt":0.2818952250427664,"spread":0.267137664537853,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003989402,0.0006502659,0.001066356,0.00005198366,0.0004393285,0.00005005477,0.0007151546,0.001327677,0.0002276985],"category_scores_gemma":[0.0003050593,0.0003181707,0.0007897901,0.000188401,0.0003769469,0.000002467457,0.0006410796,0.001163265,0.0002072848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003206414,"about_ca_system_score_gemma":0.0000863015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002841848,"about_ca_topic_score_gemma":0.000004572618,"domain_scores_codex":[0.9970172,0.0009953724,0.0005727015,0.000900254,0.0001179233,0.0003965453],"domain_scores_gemma":[0.9978166,0.00003700796,0.0004777521,0.001366539,0.00004804038,0.0002540713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001937107,0.00003439106,0.000007319794,0.003713598,0.0002463117,0.00001719555,0.0000129787,2.055181e-7,0.002372672,0.001020605,0.09029238,0.902263],"study_design_scores_gemma":[0.0001207821,0.00009477737,0.000004661454,0.0003335002,0.000772742,0.00003644747,0.000002008993,3.713118e-7,0.00002085926,0.00003192356,0.998198,0.0003839086],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006070839,0.9939421,0.00001015923,0.0003033741,0.0004484389,0.001342432,0.00004699175,0.00001506365,0.003830774],"genre_scores_gemma":[0.0001945738,0.9928969,0.00004758984,0.003852362,0.0006374772,0.00008907683,0.0006833146,0.0001028977,0.001495826],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9079056,"threshold_uncertainty_score":0.9999688,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2044025778","doi":"10.1038/nrm2466","title":"The promise of human induced pluripotent stem cells for research and therapy","year":2008,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":419,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Juvenile Diabetes Research Foundation","funders":"","keywords":"Induced pluripotent stem cell; Reprogramming; Embryonic stem cell; Regenerative medicine; Somatic cell; Human Induced Pluripotent Stem Cells; Stem cell; Biology; Cell therapy; Cell potency; Cell biology; Cell; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.109004600548994,"gpt":0.4171959208418612,"spread":0.3081913202928672,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.002302787,0.0007596422,0.00216702,0.0002662314,0.0004694619,0.0000438526,0.001516055,0.002501108,0.000003647646],"category_scores_gemma":[0.0001518323,0.0004606314,0.001053402,0.0004553314,0.0006845725,0.000003273269,0.0006539342,0.001814316,0.00001458355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006048164,"about_ca_system_score_gemma":0.0005034209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007449711,"about_ca_topic_score_gemma":0.000005133768,"domain_scores_codex":[0.9934129,0.00248229,0.001308367,0.001391272,0.0003812048,0.001023966],"domain_scores_gemma":[0.996442,0.0003339484,0.0007919748,0.001664856,0.0005473724,0.0002199072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004722966,0.0001088081,8.558733e-7,0.005534609,0.0001925944,0.000008141907,0.000007149598,5.175187e-8,0.2823434,0.0001176012,0.001942269,0.7096974],"study_design_scores_gemma":[0.0005001536,0.001402577,1.089271e-7,0.0009804603,0.00006645174,0.00002772514,0.000005871378,5.438685e-7,0.08268777,0.00005421328,0.9138911,0.0003829737],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007075252,0.9906872,0.00002519211,0.00003581676,0.0002268998,0.00768332,0.0000840452,0.000008995811,0.0005409993],"genre_scores_gemma":[0.0002848818,0.9963359,0.0001703201,0.0000481474,0.0002330837,0.001351,0.0003850782,0.0001338153,0.00105777],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9119489,"threshold_uncertainty_score":0.9997845,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4396515574","doi":"10.1038/s41580-024-00730-2","title":"Fundamentals of redox regulation in biology","year":2024,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":417,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"National Institute on Aging; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Deutsche Forschungsgemeinschaft","keywords":"Redox; Computational biology; Biology; Cell biology; Chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.01822597686525396,"gpt":0.3751872539870407,"spread":0.3569612771217867,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.000887117,0.0008390846,0.002792448,0.0004498814,0.00003334334,0.00001109916,0.0007468008,0.00421951,0.00005814098],"category_scores_gemma":[0.0002490027,0.0006018777,0.001201184,0.0006061855,0.0003921178,0.000003611347,0.0004241763,0.001339027,0.0001092237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006888501,"about_ca_system_score_gemma":0.0002387059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000765496,"about_ca_topic_score_gemma":0.0000150712,"domain_scores_codex":[0.994722,0.001740775,0.001544944,0.001380624,0.00007709423,0.0005345818],"domain_scores_gemma":[0.9978647,0.00005838205,0.0008930913,0.001017907,0.00007714758,0.00008880404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003244528,0.00011565,0.00004646296,0.0151705,0.0003282091,0.0000219692,0.00001039054,6.646794e-7,0.07100403,0.00249427,0.001936918,0.9088385],"study_design_scores_gemma":[0.0002103098,0.000323938,0.00000239677,0.003356018,0.000493528,0.0000233821,0.000002805928,6.309273e-7,0.006421986,0.000543255,0.9881052,0.0005165116],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001043441,0.9927641,0.0002022069,0.00002106095,0.0007562864,0.00157127,0.0002358078,0.00001486044,0.004330028],"genre_scores_gemma":[0.001324438,0.9919535,0.0005679747,0.0001363222,0.0002300103,0.0002296364,0.005060171,0.0000799591,0.0004179701],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9861683,"threshold_uncertainty_score":0.9996433,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W1516410466","doi":"10.1038/35067005","title":"Tie receptors: new modulators of angiogenic and lymphangiogenic responses","year":2001,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Lymphatic System and Diseases","field":"Medicine","cited_by":411,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Angiogenesis; Receptor; Biology; Neovascularization; Cell biology; Lymphangiogenesis; Neuroscience; Cancer; Cancer research; Metastasis; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.03129550288080033,"gpt":0.3486571619389767,"spread":0.3173616590581764,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005540274,0.0008126587,0.004768992,0.0005609936,0.00003785943,0.0000116821,0.0003199831,0.001942452,0.0001220868],"category_scores_gemma":[0.0007039107,0.0005479289,0.002314764,0.0009305298,0.0001557825,0.00002817265,0.0001457054,0.0001562206,0.000131413],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000150446,"about_ca_system_score_gemma":0.0008720901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001871172,"about_ca_topic_score_gemma":9.019582e-7,"domain_scores_codex":[0.9958133,0.001100698,0.001481929,0.0009029455,0.0002222117,0.0004789614],"domain_scores_gemma":[0.9970351,0.0002678652,0.001024738,0.001093923,0.0001017044,0.0004767087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004666498,0.00008507974,0.00007296968,0.02835739,0.0004453696,0.00008520622,0.00001108137,1.331654e-8,0.0001760457,0.00006669013,0.005851588,0.9648019],"study_design_scores_gemma":[0.0006879587,0.0002443959,0.000002846018,0.01368514,0.00522706,0.0004265338,0.000003385745,2.918576e-7,0.0001011436,0.00004484903,0.979156,0.0004204537],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006504075,0.995415,0.00007194733,0.00004704465,0.0004986578,0.002551667,0.00005150964,0.00004471822,0.001254453],"genre_scores_gemma":[0.00008830505,0.996446,0.0008053368,0.0004433031,0.0003521197,0.00009271714,0.0004826855,0.0001002746,0.001189324],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9733043,"threshold_uncertainty_score":0.9996972,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3152172570","doi":"10.1038/s41580-021-00356-8","title":"Intracellular mRNA transport and localized translation","year":2021,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":390,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Intellectual and Developmental Disabilities Research Center; National Institutes of Health","keywords":"Translation (biology); Messenger RNA; Cell biology; Ribonucleoprotein; P-bodies; Gene expression; Biology; Messenger RNP; RNA; Protein biosynthesis; Protein subcellular localization prediction; Multicellular organism; Gene; Molecular biology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.02251424285189532,"gpt":0.333219087987531,"spread":0.3107048451356357,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008179466,0.00073532,0.002374511,0.0001576284,0.00008750905,0.00002942005,0.0004418313,0.002648617,0.00005126537],"category_scores_gemma":[0.0001369827,0.0005790883,0.001090161,0.0003425126,0.000162165,0.000003984162,0.0001071281,0.001382456,0.00002441103],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000287705,"about_ca_system_score_gemma":0.0003097106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006689329,"about_ca_topic_score_gemma":0.000008863194,"domain_scores_codex":[0.9959184,0.001142589,0.0009345701,0.001236796,0.0001661567,0.0006014835],"domain_scores_gemma":[0.9984037,0.0000444101,0.0003587708,0.0008438061,0.00009405915,0.0002552245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001015446,0.0000403144,0.00000357977,0.007181468,0.0001551624,0.00008226392,0.000003785831,3.511574e-7,0.0396189,0.00009601755,0.0002485899,0.9525594],"study_design_scores_gemma":[0.0003337355,0.0001549178,1.256769e-7,0.002004597,0.0004980132,0.00007706905,0.000002147251,0.000004460944,0.002630398,0.00001120515,0.9937291,0.0005542852],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000104301,0.994287,0.002801193,0.00003348774,0.0001825415,0.001469803,0.0000518058,0.00001543137,0.001054404],"genre_scores_gemma":[0.00006881093,0.9926996,0.002057729,0.0002408581,0.0002144595,0.0001601416,0.00393948,0.00009607321,0.0005228273],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9934804,"threshold_uncertainty_score":0.999666,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2020018374","doi":"10.1038/nrm1711","title":"Proteomics of organelles and large cellular structures","year":2005,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":390,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University","funders":"","keywords":"Proteomics; Organelle; Computational biology; Identification (biology); Biology; Systems biology; Cell biology; Chemistry; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.01424334515701929,"gpt":0.3313732263286726,"spread":0.3171298811716532,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0002345277,0.0006547724,0.002386791,0.00010855,0.00006717626,0.00001225486,0.0006100714,0.002314074,0.0002005069],"category_scores_gemma":[0.00008299726,0.0004933588,0.0004889239,0.0002250974,0.0001346108,0.00002019952,0.0002902286,0.001707488,0.00001299218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005660511,"about_ca_system_score_gemma":0.0001014032,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001407476,"about_ca_topic_score_gemma":6.811919e-7,"domain_scores_codex":[0.9976276,0.000128709,0.001015472,0.0007673139,0.00008556282,0.0003754078],"domain_scores_gemma":[0.9976573,0.00006387415,0.001155627,0.0009588164,0.00006497248,0.00009942381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000002064908,0.00004410133,7.193377e-7,0.02301011,0.00005244084,0.00000489953,0.000005760078,9.920508e-8,0.03596435,0.008179003,0.000107075,0.9326293],"study_design_scores_gemma":[0.0001009577,0.00001836987,4.966552e-9,0.001787909,0.0003924635,0.00001738497,0.000001335168,0.000001241965,0.03368184,0.001446939,0.962135,0.000416611],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001162663,0.9889448,0.006840052,0.00001219258,0.00002917739,0.001466367,0.0002763485,0.00005623938,0.002363235],"genre_scores_gemma":[0.00003136507,0.933271,0.06514243,0.00006379744,0.0001387027,0.0003882014,0.000732997,0.00008946019,0.0001420738],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9620278,"threshold_uncertainty_score":0.9997518,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}