{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":17,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":17,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"5ffc2250a2c6","filters":{"venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics"}},"results":[{"id":"W2396377009","doi":"10.3727/000000006783980937","title":"Increased Preclinical Efficacy of Irinotecan and Floxuridine Coencapsulated Inside Liposomes Is Associated With Tumor Delivery of Synergistic Drug Ratios","year":2006,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"Cancer therapeutics and mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Celator Pharmaceuticals (Canada)","funders":"","keywords":"Floxuridine; Irinotecan; In vivo; Pharmacology; Liposome; Chemistry; Antagonism; Drug; In vitro; Drug delivery; Chemotherapy; Medicine; Internal medicine; Cancer; Fluorouracil; Biochemistry; Biology; Colorectal cancer","authors":[{"name":"Troy O. Harasym","is_ca":true},{"name":"Paul Tardi","is_ca":true},{"name":"Natashia Harasym","is_ca":true},{"name":"Pierrot Harvie","is_ca":true},{"name":"Sharon A. Johnstone","is_ca":true},{"name":"Lawrence D. Mayer","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08306341216471885,"gpt":0.4170311847761984,"spread":0.3339677726114795,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002765417,0.0003044903,0.0009665588,0.0001044955,0.0001634279,0.00002827373,0.000344085,0.0005632362,0.00002886547],"category_scores_gemma":[0.0006439472,0.0002456256,0.0001941994,0.0003176755,0.001810902,0.00001158034,0.0003528005,0.0009232245,7.942591e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005711009,"about_ca_system_score_gemma":0.0009743323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005695212,"about_ca_topic_score_gemma":0.001322079,"domain_scores_codex":[0.9957756,0.00106351,0.001307612,0.0008311396,0.0004737802,0.0005484014],"domain_scores_gemma":[0.9949429,0.002931711,0.0005345404,0.000508212,0.0008241817,0.0002584365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0403712,0.01339561,0.2875898,0.0006547554,0.007263508,0.0001217729,0.0005018204,0.0002297109,0.4709755,0.001196404,0.001874293,0.1758256],"study_design_scores_gemma":[0.03087851,0.02950236,0.5110707,0.001162151,0.001918876,0.00004778014,0.000226822,0.001498345,0.3897626,0.003194243,0.02926505,0.001472632],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918693,0.005970476,0.00003272831,0.001030863,0.0001790361,0.0005749493,0.0001160354,0.00001961667,0.0002070477],"genre_scores_gemma":[0.9899868,0.0080874,0.0004091663,0.0006152107,0.0003730706,0.00004705228,0.00005857152,0.00004884816,0.0003738756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2234809,"threshold_uncertainty_score":0.9999996,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2033883294","doi":"10.3727/096504008786111356","title":"Synergistic Effect of 5-Aza-2′-Deoxycytidine and Genistein in Combination Against Leukemia","year":2008,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"Childhood Cancer Survivors' Quality of Life","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"","keywords":"Genistein; Deoxycytidine; Leukemia; Azacitidine; Decitabine; Cancer research; Myeloid leukemia; Pharmacology; Cytarabine; Cell culture; DNA methylation; Chemistry; Biology; Medicine; Immunology; Cancer; Internal medicine; Biochemistry; Genetics","authors":[{"name":"Noël J.‐M. Raynal","is_ca":true},{"name":"Michel Charbonneau","is_ca":false},{"name":"Louise F. Momparler","is_ca":false},{"name":"Richard L. Momparler","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2225252991633564,"gpt":0.5207685682122231,"spread":0.2982432690488667,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008191084,0.0002455103,0.001365819,0.0001942475,0.000178167,0.00001342298,0.0002088717,0.0006674781,0.00002251332],"category_scores_gemma":[0.002901052,0.000199916,0.0001711354,0.0004456353,0.002223504,0.00006909963,0.0002763313,0.002238651,0.00000491739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003693531,"about_ca_system_score_gemma":0.001067907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003715552,"about_ca_topic_score_gemma":0.0004941101,"domain_scores_codex":[0.9941652,0.002510873,0.001387766,0.0007092515,0.0006760897,0.0005508285],"domain_scores_gemma":[0.9855129,0.01309066,0.0002583366,0.000429789,0.0003162581,0.0003921008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008425267,0.001135716,0.8164917,0.0007761926,0.000446676,0.0001676787,0.0006549907,0.000008021655,0.001129193,0.0001656043,0.0002823907,0.1703165],"study_design_scores_gemma":[0.01738884,0.0139598,0.9560768,0.0008486768,0.0002498225,0.00005150187,0.000104636,0.0006951272,0.002435073,0.0005405563,0.007339783,0.0003093921],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985635,0.005927516,0.00001095895,0.006320569,0.0003202818,0.0008110405,0.00001163008,0.00003866991,0.0009243171],"genre_scores_gemma":[0.9665183,0.03129944,0.000282871,0.001000025,0.0003907946,0.00007404308,0.00001266578,0.00003401088,0.000387855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1700071,"threshold_uncertainty_score":0.972595,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2945780887","doi":"10.3727/096504019x15579146061957","title":"Profilin 2 Promotes Proliferation and Metastasis of Head and Neck Cancer Cells by Regulating PI3K/AKT/β-Catenin Signaling Pathway","year":2019,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"","keywords":"Protein kinase B; Downregulation and upregulation; Gene knockdown; Cancer research; PI3K/AKT/mTOR pathway; Metastasis; Cell growth; Catenin; Biology; Signal transduction; Cancer; Cell culture; Wnt signaling pathway; Cell biology; Gene","authors":[{"name":"Kecheng Zhou","is_ca":false},{"name":"Jie Chen","is_ca":false},{"name":"Jiayu Wu","is_ca":false},{"name":"Yangxinzi Xu","is_ca":true},{"name":"Qiaoyun Wu","is_ca":false},{"name":"Jingjing Yue","is_ca":false},{"name":"Yu Song","is_ca":false},{"name":"Shengcun Li","is_ca":false},{"name":"Peng Zhou","is_ca":false},{"name":"Wenzhan Tu","is_ca":false},{"name":"Guanhu Yang","is_ca":false},{"name":"Songhe Jiang","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1209927072582436,"gpt":0.4556264656787377,"spread":0.3346337584204941,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002183382,0.0001870089,0.0004703487,0.00004829596,0.0001648713,0.00005020709,0.0001481213,0.0004741362,0.00004339466],"category_scores_gemma":[0.0002097702,0.0001550962,0.00009364423,0.000122275,0.0003604521,0.00001684802,0.0002944407,0.0007656393,0.000001507754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002865728,"about_ca_system_score_gemma":0.0002999878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000945679,"about_ca_topic_score_gemma":0.0001574128,"domain_scores_codex":[0.9973747,0.0006433284,0.0006874984,0.0006898002,0.0002302899,0.0003744071],"domain_scores_gemma":[0.9983621,0.0006212218,0.0002326665,0.0002481543,0.0003528296,0.0001830325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009733263,0.0003672687,0.03842421,0.0001515646,0.0003625574,0.000001058024,0.0001051929,0.000009258309,0.8396711,0.00008784186,0.0001298932,0.1197168],"study_design_scores_gemma":[0.003007083,0.006375747,0.004567831,0.000257634,0.0001588786,0.00001043908,0.0001907813,0.00192162,0.9485481,0.0005307097,0.03406132,0.000369821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885258,0.008845445,0.00004683122,0.001475375,0.0002524088,0.0006632525,0.00006438392,0.000009482592,0.0001170371],"genre_scores_gemma":[0.9854376,0.01178224,0.001082474,0.0002638292,0.0002619134,0.00009374502,0.00003356328,0.00003028635,0.001014372],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1193469,"threshold_uncertainty_score":0.6324639,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2029216847","doi":"10.3727/096504011x13021877989874","title":"A Conjugate of Gemcitabine With Bisphosphonate (Gem/BP) Shows Potential as a Targeted Bone-Specific Therapeutic Agent in an Animal Model of Human Breast Cancer Bone Metastases","year":2011,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Alberta Cancer Foundation","funders":"","keywords":"Gemcitabine; Medicine; Bisphosphonate; Breast cancer; Bone metastasis; Medullary cavity; Metastatic breast cancer; Cancer; Periosteum; Metastasis; Pathology; Internal medicine; Oncology; Osteoporosis","authors":[{"name":"Amal El-Mabhouh","is_ca":true},{"name":"P. N. Nation","is_ca":false},{"name":"Jonathan Abele","is_ca":false},{"name":"Terence Riauka","is_ca":false},{"name":"Ernst J. Postema","is_ca":false},{"name":"A. J. B. McEwan","is_ca":false},{"name":"John R. Mercer","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.3272237031578544,"gpt":0.5101515712237648,"spread":0.1829278680659103,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002358,0.0003190901,0.001275979,0.0001337474,0.0001513264,0.00001709538,0.000341635,0.0005007881,0.0005171546],"category_scores_gemma":[0.00004893389,0.0002379017,0.000223324,0.0005057037,0.002448767,0.0001167504,0.0001837663,0.001899814,0.000002638322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001320608,"about_ca_system_score_gemma":0.0007758071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003520142,"about_ca_topic_score_gemma":0.0002987237,"domain_scores_codex":[0.9958014,0.0005820337,0.001456943,0.0008483638,0.000616452,0.0006948136],"domain_scores_gemma":[0.9971096,0.0006687253,0.0003634466,0.0005800048,0.0007167289,0.0005614865],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.09325733,0.01865722,0.1912182,0.0008550349,0.002456798,0.0003496978,0.001270701,0.0002226776,0.55687,0.002411721,0.00009918659,0.1323314],"study_design_scores_gemma":[0.04168541,0.02787589,0.6928246,0.001343523,0.003365531,0.0003777025,0.001202063,0.01448736,0.2043544,0.007115458,0.003794207,0.00157383],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901667,0.005797155,0.00003614829,0.002413743,0.00006093782,0.0008615124,0.0002174422,0.00003632163,0.0004100533],"genre_scores_gemma":[0.9867795,0.0108304,0.001044445,0.0005901575,0.0001407039,0.0002527675,0.00002296417,0.00005043365,0.0002886716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5016063,"threshold_uncertainty_score":0.9701349,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2000121640","doi":"10.3727/096504010x12704916124828","title":"The Inhibitor of Growth 1 (ING1) Is Involved in Trichostatin A-Induced Apoptosis and Caspase 3 Signaling in p53-Deficient Glioblastoma Cells","year":2009,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Trichostatin A; Cancer research; Apoptosis; Biology; Gene knockdown; Glioma; Histone; Histone deacetylase; Histone deacetylase inhibitor; Death domain; DNA damage; Molecular biology; Programmed cell death; DNA; Genetics","authors":[{"name":"Mona Tamannai","is_ca":false},{"name":"Sonja Farhangi","is_ca":false},{"name":"Matthias Truß","is_ca":false},{"name":"Brigitte Sinn","is_ca":false},{"name":"Reinhard Würm","is_ca":false},{"name":"Pinaki Bose","is_ca":true},{"name":"Guenter Henze","is_ca":false},{"name":"Karl Riabowol","is_ca":true},{"name":"Andreas von Deimling","is_ca":false},{"name":"Gesche Tallen","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1066155865699579,"gpt":0.4595628890268401,"spread":0.3529473024568821,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006536738,0.0002277862,0.0005621588,0.00019318,0.0002178967,0.00005152828,0.000401571,0.0006856105,0.000006403773],"category_scores_gemma":[0.001363629,0.0001760108,0.0001292307,0.0006043764,0.0009635882,0.00001157531,0.0003438276,0.001762966,0.000002164675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001347077,"about_ca_system_score_gemma":0.0006221851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002237694,"about_ca_topic_score_gemma":0.00114236,"domain_scores_codex":[0.9949786,0.001752466,0.001180721,0.0008023742,0.0005107156,0.0007751295],"domain_scores_gemma":[0.9957973,0.002914419,0.0002022939,0.0004012738,0.000420021,0.0002646541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009516953,0.002149325,0.04118517,0.0001200665,0.0001761536,0.00003984664,0.0009969448,0.00002200015,0.7524427,0.00007552116,0.0008519625,0.1924233],"study_design_scores_gemma":[0.006834549,0.01277145,0.02713965,0.0003115974,0.00004710777,0.000006065885,0.0007525689,0.0003829508,0.9426008,0.000710592,0.007977076,0.0004656277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902206,0.004144449,0.000003487571,0.004707556,0.0001934692,0.0005848103,0.00001614178,0.000007497884,0.0001219713],"genre_scores_gemma":[0.984931,0.01381387,0.0001682971,0.0005750631,0.0002577584,0.00006512412,0.000003509582,0.00002375544,0.0001616328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1919577,"threshold_uncertainty_score":0.7659308,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2015557135","doi":"10.3727/096504009789954645","title":"The Inhibitor of Growth 1 (ING1) Proteins Suppress Angiogenesis and Differentially Regulate Angiopoietin Expression in Glioblastoma Cells","year":2009,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Angiogenesis; Cancer research; Biology; Gene knockdown; Neovascularization; Angiopoietin; Cell growth; Glioma; Cell biology; Cell culture; Vascular endothelial growth factor; Genetics","authors":[{"name":"Gesche Tallen","is_ca":false},{"name":"Sonja Farhangi","is_ca":false},{"name":"Mona Tamannai","is_ca":false},{"name":"Nikola Holtkamp","is_ca":false},{"name":"Dorothea Mangoldt","is_ca":false},{"name":"Sitar Shah","is_ca":true},{"name":"Keiko Suzuki","is_ca":true},{"name":"Matthias Truß","is_ca":false},{"name":"Guenter Henze","is_ca":false},{"name":"Karl Riabowol","is_ca":true},{"name":"Andreas von Deimling","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05617818447681536,"gpt":0.418285662855758,"spread":0.3621074783789426,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003414314,0.0002329223,0.00047755,0.0001101878,0.0002659477,0.00006286321,0.0004961377,0.0008017818,0.0000108904],"category_scores_gemma":[0.0005587015,0.0001701972,0.000181581,0.0003055093,0.001043098,0.00001043049,0.0005860575,0.001086977,9.961541e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007322275,"about_ca_system_score_gemma":0.0004279768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005116204,"about_ca_topic_score_gemma":0.0004635567,"domain_scores_codex":[0.9955495,0.001617696,0.0008325311,0.00078451,0.0005080515,0.000707696],"domain_scores_gemma":[0.9976487,0.0009660102,0.0001919485,0.0005112053,0.0004179327,0.00026423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006739276,0.0005546305,0.002192313,0.00006315614,0.0001820782,0.00001717861,0.0001012471,0.00002064884,0.8797602,0.00007102716,0.0003660837,0.1099321],"study_design_scores_gemma":[0.003830665,0.008718671,0.03661047,0.0002788357,0.00007119999,0.00001205589,0.00009094815,0.0002541805,0.9342862,0.001379979,0.0141252,0.0003415817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861941,0.009307998,0.0001458971,0.003069961,0.0002514218,0.0008837055,0.00002009553,0.00001377693,0.0001130349],"genre_scores_gemma":[0.9664248,0.03197196,0.0004371493,0.000211716,0.0004045986,0.0000959521,0.000005318299,0.00003262729,0.0004158982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1095905,"threshold_uncertainty_score":0.6940441,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4388712457","doi":"10.32604/or.2023.030401","title":"Biological, pathological, and multifaceted therapeutic functions of exosomes to target cancer","year":2023,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Durham College","funders":"Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education","keywords":"Microvesicles; Exosome; Intracellular; Cell biology; Function (biology); microRNA; Biology; Biochemistry; Gene","authors":[{"name":"Vignesh Balaji E","is_ca":false},{"name":"Divya Ramesh","is_ca":false},{"name":"MANISHA CHUNGAN SHAJU","is_ca":true},{"name":"Ajith Kumar","is_ca":false},{"name":"SAMYAK PANDEY","is_ca":false},{"name":"RAKSHA NAYAK","is_ca":false},{"name":"V. ALKA","is_ca":false},{"name":"SRISHTI MUNJAL","is_ca":false},{"name":"AMIR SALIMI","is_ca":false},{"name":"K. Sreedhara Ranganath Pai","is_ca":false},{"name":"Shankar M Bakkannavar","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2954338355755112,"gpt":0.527769437303063,"spread":0.2323356017275518,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003039503,0.0002387681,0.0005575037,0.0001144737,0.0002634159,0.00003391212,0.0004027885,0.0007619532,0.00007351513],"category_scores_gemma":[0.001153,0.0001818308,0.0001692405,0.0005182418,0.001712889,0.000007970638,0.0008168713,0.0008546048,0.00002175152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003212693,"about_ca_system_score_gemma":0.0003204474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003027727,"about_ca_topic_score_gemma":0.00005373476,"domain_scores_codex":[0.9960318,0.001326244,0.0007432763,0.0009434227,0.0002921437,0.000663122],"domain_scores_gemma":[0.996855,0.001683235,0.000148278,0.0004941938,0.000373661,0.0004456593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002854554,0.001088064,0.4756633,0.0000937997,0.0007191665,0.00004567717,0.0002045105,0.0001090122,0.1598597,0.0001223661,0.00179217,0.3574477],"study_design_scores_gemma":[0.002973445,0.006879481,0.7330332,0.0001085027,0.0001731007,0.00001636257,0.0006031456,0.0004058536,0.008858944,0.002387059,0.2439901,0.0005707915],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9773803,0.01530847,0.00009357814,0.005862336,0.0003852551,0.0005967766,0.0001371996,0.00005772595,0.000178298],"genre_scores_gemma":[0.9375533,0.05773491,0.0009578191,0.001537004,0.0004589538,0.0002921778,0.00003920928,0.00003602838,0.00139062],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3568769,"threshold_uncertainty_score":0.7414843,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2314201732","doi":"10.3727/096504011x13021877989793","title":"Evaluation of an <SUP>18</SUP>F-Labeled Oligonucleotide Probe Targeting <I>p21<SUP>WAF1</SUP></I> Transcriptional Changes in Human Tumor Cells","year":2011,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Transfection; Molecular biology; Oligonucleotide; Biology; Liposome; Intracellular; Cytoplasm; Cell culture; Cell biology; Biochemistry; Gene","authors":[{"name":"Ingrid L. Koslowsky","is_ca":true},{"name":"Soraya Shahhosseini","is_ca":false},{"name":"Razmik Mirzayans","is_ca":false},{"name":"David Murray","is_ca":false},{"name":"John R. Mercer","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1806787531270636,"gpt":0.4567955468700063,"spread":0.2761167937429427,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.01658676,0.000923028,0.001888698,0.0004511972,0.0006877072,0.0001148962,0.001322272,0.001999962,0.0002087875],"category_scores_gemma":[0.001466129,0.0008135656,0.0006951038,0.000846672,0.002678506,0.0000875515,0.000687428,0.002236543,0.00001320735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004038603,"about_ca_system_score_gemma":0.001237575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005241559,"about_ca_topic_score_gemma":0.003093818,"domain_scores_codex":[0.9857785,0.005236544,0.002756392,0.002452076,0.00192588,0.001850659],"domain_scores_gemma":[0.9934051,0.001212927,0.0009351957,0.001344804,0.002351579,0.0007504055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003642517,0.003481201,0.002842932,0.0002071383,0.001122181,0.00005720475,0.0005220543,0.0001457207,0.9219051,0.0002800427,0.001010451,0.06478346],"study_design_scores_gemma":[0.02075362,0.02686923,0.0517455,0.001385781,0.003575062,0.0001053066,0.0004613796,0.01757545,0.6166031,0.008108954,0.2487225,0.004094086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868306,0.007056685,0.000147415,0.001746928,0.0003547453,0.001834003,0.0002429055,0.0001501329,0.001636619],"genre_scores_gemma":[0.9724534,0.01395533,0.009219821,0.001013899,0.001552141,0.0003456374,0.000359852,0.0001583283,0.0009416271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.305302,"threshold_uncertainty_score":0.9994315,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4405265943","doi":"10.32604/or.2024.055155","title":"Biomarkers for predicting bladder cancer therapy response","year":2024,"lang":"en","type":"review","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Bladder cancer; Cancer therapy; Medicine; Oncology; Cancer; Internal medicine","authors":[{"name":"Ioana Maria Mihai","is_ca":true},{"name":"Gang Wang","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.5279350147086131,"gpt":0.6319476790168104,"spread":0.1040126643081972,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.008848933,0.000880071,0.00396153,0.0004181816,0.000443833,0.0001546686,0.0005578901,0.002635841,0.0001921614],"category_scores_gemma":[0.001052358,0.0005702676,0.001728554,0.0008705477,0.00159291,0.00007753664,0.0004286784,0.004861719,0.00005125542],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00091805,"about_ca_system_score_gemma":0.008190857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001598972,"about_ca_topic_score_gemma":0.0001291609,"domain_scores_codex":[0.9905689,0.002989735,0.002229927,0.002031493,0.000806066,0.001373841],"domain_scores_gemma":[0.9816214,0.01555184,0.0004400772,0.0008818255,0.0006946952,0.0008101391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01260768,0.0008786729,0.001001922,0.005682375,0.01250065,0.00008819428,0.0001255067,7.782926e-8,0.000002383742,0.00001424681,0.0057483,0.96135],"study_design_scores_gemma":[0.004761606,0.007224567,0.000625638,0.01118146,0.009187144,0.00006916222,0.0000533317,0.00002624217,0.000005668796,0.000297696,0.9660689,0.0004985796],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006539993,0.9825537,0.000004250906,0.007692981,0.002659711,0.005070936,0.0006237628,0.0001943386,0.0005462705],"genre_scores_gemma":[0.0001129579,0.9815434,0.0003977949,0.001433063,0.00384574,0.004319231,0.00006800645,0.0002905028,0.007989359],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9608514,"threshold_uncertainty_score":0.9996749,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4285823231","doi":"10.32604/or.2022.03529","title":"cGAS regulates the DNA damage response to maintain proliferative signaling in gastric cancer cells","year":2021,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University","funders":"National Key Research and Development Program of China; Zhengzhou University","keywords":"Cancer; Genome instability; Cancer research; DNA damage; Cancer cell; Biology; Gene silencing; Ectopic expression; Cell growth; Downregulation and upregulation; Metastasis; Tumor progression; Cell biology; Cell culture; DNA; Genetics; Gene","authors":[{"name":"Bin Liu","is_ca":false},{"name":"HAIPENG LIU","is_ca":false},{"name":"Feifei Ren","is_ca":false},{"name":"Hangfan Liu","is_ca":false},{"name":"Ihtisham Bukhari","is_ca":false},{"name":"YUMING FU","is_ca":false},{"name":"WANQING WU","is_ca":false},{"name":"MINGHAI ZHAO","is_ca":false},{"name":"SHAOGONG ZHU","is_ca":false},{"name":"Hui Mo","is_ca":false},{"name":"Fazhan Li","is_ca":false},{"name":"MICHAEL B. ZHENG","is_ca":true},{"name":"Youcai Tang","is_ca":false},{"name":"Pengyuan Zheng","is_ca":false},{"name":"Yang Mi","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1582064670932602,"gpt":0.497036857738369,"spread":0.3388303906451088,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006125211,0.0002118747,0.0004164057,0.00007855303,0.0003256618,0.00009160247,0.000463646,0.0004906195,0.00007908728],"category_scores_gemma":[0.0009755974,0.0001559937,0.0001415739,0.0006112932,0.0006953903,0.0000093747,0.0004889334,0.001265276,0.000008947981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001585356,"about_ca_system_score_gemma":0.001664393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007225312,"about_ca_topic_score_gemma":0.001227146,"domain_scores_codex":[0.9938972,0.003477573,0.0007304703,0.0008923304,0.0003315274,0.0006709138],"domain_scores_gemma":[0.9962065,0.002182438,0.000123655,0.0006272329,0.0005862006,0.0002740131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01266317,0.001188233,0.05443404,0.00004965047,0.000600893,0.00008200933,0.000624872,0.001047154,0.7895679,0.0002487857,0.002193008,0.1373003],"study_design_scores_gemma":[0.005165553,0.004707967,0.3318929,0.0003193748,0.0001821354,0.00002783479,0.001694241,0.0004341157,0.2943833,0.001860186,0.3585407,0.0007916705],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9673483,0.005418802,0.00006165976,0.02602029,0.0003270895,0.0005778919,0.00004111485,0.00001138801,0.000193509],"genre_scores_gemma":[0.9765344,0.01495883,0.0007941928,0.003480206,0.0008127808,0.0004995718,0.00001311141,0.00003747679,0.002869435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4951846,"threshold_uncertainty_score":0.636124,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2418845263","doi":"10.3727/000000006783981279","title":"Are CYP17 Genotypes a Biomarker for Ovarian Cancer in Patients With Cancer History in Their Family?","year":2006,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"","keywords":"Ovarian cancer; Genotype; Breast cancer; Oncology; Allele; Internal medicine; Family history; Medicine; Cancer; Allele frequency; Gene; Biology; Genetics","authors":[{"name":"Hülya Yazıcı","is_ca":false},{"name":"Hulya Tigli","is_ca":false},{"name":"Z. Kadehci","is_ca":false},{"name":"Seden Küçücük","is_ca":false},{"name":"Pınar Saip","is_ca":false},{"name":"Halim İşsever","is_ca":false},{"name":"Hilmi Özçelik","is_ca":true},{"name":"Nejat Dalay","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1575068503135432,"gpt":0.4542479661299715,"spread":0.2967411158164283,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001841825,0.0002622365,0.0005432262,0.0001420783,0.0001063727,0.00002341427,0.0003658929,0.0007259135,0.00004576849],"category_scores_gemma":[0.0001816735,0.0002084954,0.0001166989,0.0002781292,0.0008553392,0.00001301985,0.0001953468,0.0008698531,0.000001127839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008903918,"about_ca_system_score_gemma":0.001615405,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001294205,"about_ca_topic_score_gemma":0.03164469,"domain_scores_codex":[0.996819,0.0005139908,0.0007589314,0.0009353291,0.0002731701,0.0006996423],"domain_scores_gemma":[0.9978932,0.0007867551,0.0002771917,0.0004042637,0.0005071916,0.000131396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00474818,0.0008530647,0.8649178,0.00005286483,0.0002336765,0.000003924975,0.00007789053,0.0001760009,0.0006016594,0.00001994462,0.002106329,0.1262087],"study_design_scores_gemma":[0.005313962,0.0007528195,0.8073901,0.0001100027,0.00004441119,4.007531e-7,0.00006202416,0.0001140198,0.0001737418,0.0002765033,0.1855124,0.0002495845],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9683998,0.02584603,0.00003184285,0.003411356,0.0007322805,0.001001449,0.0002182116,0.00001384904,0.0003451451],"genre_scores_gemma":[0.9849132,0.009804691,0.0005875835,0.001820316,0.0007381913,0.001307787,0.00005431264,0.00006566843,0.0007082185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1834061,"threshold_uncertainty_score":0.9860253,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4407381812","doi":"10.32604/or.2025.060601","title":"Current innovations in head and neck cancer: From diagnostics to therapeutics","year":2025,"lang":"en","type":"review","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Head and neck cancer; Medicine; Head and neck; Current (fluid); Cancer; Medical physics; Internal medicine; Engineering; Surgery","authors":[{"name":"Tayyaba Sattar","is_ca":false},{"name":"M. A. Jabbar","is_ca":false},{"name":"Saba Afzal","is_ca":false},{"name":"Sana Hanif","is_ca":false},{"name":"Seyed Ali Mosaddad","is_ca":false},{"name":"Hamid Tebyanian","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.4949985518384427,"gpt":0.636912791138424,"spread":0.1419142392999814,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.002830646,0.0006368875,0.004365904,0.0005166199,0.0003068697,0.00007593817,0.0004518378,0.001457654,0.00004588323],"category_scores_gemma":[0.001871625,0.0004840495,0.0003664152,0.001735915,0.001039758,0.00005256315,0.0009938598,0.006177397,0.00001456948],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007013201,"about_ca_system_score_gemma":0.005207159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005065011,"about_ca_topic_score_gemma":0.003587871,"domain_scores_codex":[0.9929926,0.001520422,0.002317302,0.001524314,0.0006013749,0.00104396],"domain_scores_gemma":[0.9773992,0.02032588,0.0003126203,0.0007145727,0.0006819736,0.0005657953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005274043,0.0009706221,0.03896319,0.004361314,0.001000453,0.0000334103,0.0001765264,2.163959e-7,2.735284e-7,0.00007614868,0.001022221,0.9528682],"study_design_scores_gemma":[0.002374681,0.001891863,0.04083999,0.03530863,0.001753886,0.000004406287,0.00003618473,0.00001027792,5.881963e-7,0.0003953247,0.9169855,0.0003987336],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005344463,0.9774841,0.00000477537,0.01220625,0.001655997,0.002417975,0.0003726369,0.00005628752,0.000457487],"genre_scores_gemma":[0.0001948387,0.9927272,0.0004670225,0.003111051,0.001450939,0.001348755,0.00006083322,0.00007190403,0.0005674219],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9524695,"threshold_uncertainty_score":0.9998387,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4395470287","doi":"10.32604/or.2024.049235","title":"MicroRNAs in thyroid cancer with focus on medullary thyroid carcinoma: potential therapeutic targets and diagnostic/prognostic markers and web based tools","year":2024,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Vancouver General Hospital","funders":"","keywords":"microRNA; Thyroid carcinoma; Computational biology; Bioinformatics; Thyroid cancer; Cancer; Biology; Cancer research; Medicine; Thyroid; Internal medicine; Gene; Genetics","authors":[{"name":"Elham Shakiba","is_ca":false},{"name":"Seti Boroomand","is_ca":true},{"name":"Sima Kheradmand Kia","is_ca":false},{"name":"Mehdi Hedayati","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.06583264843647783,"gpt":0.4085500561666831,"spread":0.3427174077302052,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00203659,0.0003327496,0.0004880149,0.0001413816,0.0001833397,0.0001514183,0.0002349633,0.000669035,0.00003623111],"category_scores_gemma":[0.0005025057,0.0002565724,0.0001078233,0.0002497781,0.001200132,0.00002044533,0.0002634051,0.00125447,0.000003042656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001083019,"about_ca_system_score_gemma":0.001070786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007597861,"about_ca_topic_score_gemma":0.0005972225,"domain_scores_codex":[0.9961693,0.001114776,0.0005958243,0.001141086,0.0003183632,0.0006606494],"domain_scores_gemma":[0.9952691,0.003803134,0.00009785899,0.000355211,0.0001814228,0.0002932639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.01060966,0.00109536,0.452969,0.0005251863,0.001192039,0.0003460603,0.0001236752,0.0001316413,0.06116049,0.000134302,0.00106739,0.4706452],"study_design_scores_gemma":[0.007856376,0.008699281,0.943233,0.0007629095,0.0005545418,0.00006199504,0.000114101,0.002557652,0.006997989,0.0008526922,0.02753281,0.0007766949],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8645009,0.128279,0.00003844877,0.00583321,0.0003068722,0.000778612,0.0000895386,0.0000278302,0.0001455606],"genre_scores_gemma":[0.9589312,0.03909951,0.0002068469,0.000798822,0.000446096,0.0002551242,0.00003826872,0.00006171627,0.0001623885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4902639,"threshold_uncertainty_score":0.9999887,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2346075312","doi":"10.3727/000000003772505371","title":"Synthesis and In Vitro Cytotoxicity Studies of Novel L-Tryptophan–Polyamide Conjugates and L-Tryptophan Dimers Linked With Aliphatic Chains and Polyamides","year":2003,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":6,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Tryptophan; Pyrrole; Chemistry; Imidazole; Stereochemistry; Cytotoxicity; Biochemistry; In vitro; Organic chemistry; Amino acid","authors":[{"name":"Rohtash Kumar","is_ca":true},{"name":"Dinesh Rai","is_ca":true},{"name":"J. William Lown","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2667580644189042,"gpt":0.473662627546131,"spread":0.2069045631272269,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.003487552,0.0003265677,0.00129997,0.00008676998,0.0002369431,0.00004561237,0.0001855923,0.0006672173,0.00002816424],"category_scores_gemma":[0.003587787,0.0002153667,0.000082851,0.0002090136,0.004288397,0.00009079362,0.0003120907,0.001240915,2.954912e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007610935,"about_ca_system_score_gemma":0.0001834264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001350397,"about_ca_topic_score_gemma":0.0003266746,"domain_scores_codex":[0.9964551,0.0008737064,0.0008599944,0.0008814287,0.0003082733,0.0006214858],"domain_scores_gemma":[0.9759066,0.02305257,0.0002641316,0.000274502,0.0001923782,0.000309797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007986339,0.002571458,0.5719513,0.0008748824,0.001573007,0.00003809253,0.0004850394,0.000002103636,0.2183134,0.000394144,0.000006492525,0.1958037],"study_design_scores_gemma":[0.01071096,0.003606542,0.4542668,0.001573258,0.0006791737,0.0000997052,0.003799862,0.0007259575,0.5180978,0.003304695,0.001920538,0.001214718],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833277,0.01428046,0.000004846399,0.001697088,0.00005374831,0.0002713293,0.000049413,0.00002564064,0.0002898072],"genre_scores_gemma":[0.9468831,0.05147943,0.001033067,0.000271265,0.0001050058,0.0001020279,0.00000145935,0.00002312585,0.0001014973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2997844,"threshold_uncertainty_score":0.9984214,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4415688853","doi":"10.32604/or.2025.069408","title":"CXCR1 and CXCR2 Antagonism with G31P Attenuates Chemotherapy-Induced Lung Inflammation and Augments the Gefitinib Therapeutic Response in Lung Cancer","year":2025,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Royal University Hospital","funders":"","keywords":"Gefitinib; Antagonism; Lung cancer; Epidermal growth factor receptor; Inflammation; Tyrosine kinase; Adjuvant; Tyrosine-kinase inhibitor","authors":[{"name":"Muhammad Noman Khan","is_ca":false},{"name":"Kang Tian","is_ca":false},{"name":"John Gordon","is_ca":true},{"name":"Fang Li","is_ca":false},{"name":"Song-Ze Ding","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.11750412329387,"gpt":0.5081047822025929,"spread":0.3906006589087229,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005629255,0.0002926078,0.000806792,0.0001767782,0.0003722532,0.00009938255,0.0001994507,0.0005658157,0.00004282579],"category_scores_gemma":[0.0003642055,0.0001819279,0.00008836891,0.0005041838,0.001049343,0.0000936701,0.0002292051,0.002171455,6.702434e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002649402,"about_ca_system_score_gemma":0.0009335958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002219367,"about_ca_topic_score_gemma":0.0002714247,"domain_scores_codex":[0.9960256,0.001311145,0.0008555655,0.0007579664,0.0004220051,0.0006276726],"domain_scores_gemma":[0.9920044,0.006923045,0.0001794538,0.0003575551,0.0003101853,0.000225349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02126904,0.0003258651,0.6303958,0.0002785648,0.0008796555,0.00002453822,0.0007793226,0.000005146784,0.008151217,0.00009551015,0.00009026731,0.3377051],"study_design_scores_gemma":[0.01512517,0.002731996,0.9524155,0.001420614,0.000647596,0.0000343579,0.0005924001,0.005525903,0.006685754,0.0006921394,0.01374241,0.000386191],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9244886,0.0148653,0.00001908407,0.0590449,0.0002157845,0.001126057,0.000007757759,0.00003451239,0.0001979831],"genre_scores_gemma":[0.9545139,0.04127136,0.0001268584,0.002619395,0.0003889553,0.0002384375,0.000004977552,0.0000358879,0.0008002283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3373189,"threshold_uncertainty_score":0.9434015,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4405590313","doi":"10.32604/or.2024.055508","title":"Assessing the impact of CD73 inhibition on overcoming anti-EGFR resistance in glioma cells","year":2024,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval","funders":"","keywords":"Glioma; Resistance (ecology); Cancer research; Chemistry; Biology; Ecology","authors":[{"name":"Luiz Fernando Lopes Silva","is_ca":false},{"name":"Juliete Nathali Scholl","is_ca":false},{"name":"Augusto Ferreira Weber","is_ca":false},{"name":"Camila Kehl Dias","is_ca":false},{"name":"Pauline Rafaela Pizzato","is_ca":false},{"name":"Vinícius Pierdoná Lima","is_ca":false},{"name":"Jean Sévigny","is_ca":true},{"name":"Ana Maria Battastini","is_ca":false},{"name":"Fabrício Figueiró","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1777359199495316,"gpt":0.546116203060754,"spread":0.3683802831112224,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00402962,0.0001721226,0.0003725575,0.00009956572,0.0001375903,0.00009443941,0.0002343456,0.0004780377,0.00002287577],"category_scores_gemma":[0.0003202622,0.000111253,0.0002274405,0.0003892202,0.0006472507,0.00001661491,0.0002092754,0.001305011,0.000003344249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009114304,"about_ca_system_score_gemma":0.0005838424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001004704,"about_ca_topic_score_gemma":0.0000762217,"domain_scores_codex":[0.9969601,0.001106634,0.0006776862,0.0005633376,0.0002711452,0.0004211118],"domain_scores_gemma":[0.9965701,0.002734417,0.0001100088,0.000324609,0.0001570733,0.0001037624],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.006995734,0.003477917,0.2496455,0.0007369268,0.002414358,0.0005388231,0.001007852,0.001718799,0.534672,0.001414387,0.01805768,0.1793201],"study_design_scores_gemma":[0.008322073,0.01365269,0.6798646,0.004130356,0.0003791458,0.00007082518,0.0008270256,0.002839834,0.1658083,0.009903259,0.1127607,0.001441178],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.979094,0.0173379,0.00003736372,0.001849001,0.0002926009,0.0002391897,0.00001431764,0.00001227134,0.0011233],"genre_scores_gemma":[0.9899478,0.008593858,0.0001613136,0.0002057816,0.0007341963,0.00002721112,0.000008591368,0.00002634075,0.0002948985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4302191,"threshold_uncertainty_score":0.5669694,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4415986091","doi":"10.32604/or.2025.069230","title":"ETS Family Transcription Factors in Gastric Cancer and the Role of ELF3 in the Core Metaplasia Transcription Factor Network","year":2025,"lang":"en","type":"article","venue":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","topic":"Liver physiology and pathology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"NOSM University","funders":"","keywords":"Transcription factor; ETS transcription factor family; Transcription (linguistics); Cancer; TAF2; General transcription factor; Sp1 transcription factor; Sp3 transcription factor","authors":[{"name":"Ioannis A. Voutsadakis","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2383217852629389,"gpt":0.4978148790049809,"spread":0.259493093742042,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.004518155,0.0001811001,0.0008700074,0.0001318921,0.000153716,0.00001260845,0.0002711927,0.000662059,0.0000209004],"category_scores_gemma":[0.0002748227,0.00009755892,0.0001674462,0.0006159151,0.002059245,0.00005199635,0.00006997714,0.002692474,6.41046e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007815628,"about_ca_system_score_gemma":0.00045438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005153905,"about_ca_topic_score_gemma":0.001922878,"domain_scores_codex":[0.995304,0.002649105,0.0008540715,0.0004643797,0.0002468218,0.0004816536],"domain_scores_gemma":[0.9917186,0.007652801,0.000124642,0.0002767355,0.0001466116,0.00008058945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.010501,0.0006018946,0.8732038,0.0001020436,0.0003540462,0.00001044646,0.002041799,0.00002114408,0.002854587,0.001518928,0.00005055785,0.1087398],"study_design_scores_gemma":[0.006291904,0.001217807,0.9769934,0.0002009914,0.0002859941,0.000005212826,0.0008323661,0.0002866737,0.0001029096,0.008935034,0.004765448,0.00008224877],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9644966,0.02601499,0.000007240004,0.007619917,0.0003952755,0.0009164902,0.0000190767,0.00001068221,0.0005197176],"genre_scores_gemma":[0.9485909,0.04904035,0.00005281155,0.001821361,0.0001873161,0.0001517821,0.000006932332,0.000009753779,0.0001388172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1086575,"threshold_uncertainty_score":0.9996083,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}