{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":13,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":13,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12","author_layer_release":"2026-06-26"},"query_hash":"ae2b6699c4a0","filters":{"venue":"Pharmacogenomics and Personalized Medicine"}},"results":[{"id":"W2792357848","doi":"10.2147/pgpm.s107710","title":"CYP3A5 polymorphisms in renal transplant recipients: influence on tacrolimus treatment","year":2018,"lang":"en","type":"review","venue":"Pharmacogenomics and Personalized Medicine","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Tacrolimus; CYP3A5; Medicine; Dosing; Pharmacogenetics; Pharmacokinetics; Pharmacology; Genotype; Nephrotoxicity; Therapeutic index; Transplantation; Kidney transplantation; Therapeutic drug monitoring; Toxicity; Internal medicine; Biology; Drug; Genetics","authors":[{"name":"Lucy Chen","is_ca":true},{"name":"G. V. Ramesh Prasad","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09235587715868478,"gpt":0.4006920713580662,"spread":0.3083361941993815,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002694128,0.000829734,0.002514396,0.0005640367,0.0001077806,0.00001723703,0.0001387046,0.0002433181,0.0004565584],"category_scores_gemma":[0.00001461819,0.0005145775,0.0004081205,0.0003152726,0.0003088412,0.00004952734,0.00001383659,0.0003621331,0.00008345702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004781881,"about_ca_system_score_gemma":0.0002626682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002338281,"about_ca_topic_score_gemma":0.00001472003,"domain_scores_codex":[0.9971921,0.0001376108,0.0009553269,0.0008159181,0.0003885668,0.0005104953],"domain_scores_gemma":[0.9985828,0.0002674914,0.0003017253,0.0003031562,0.00005335254,0.0004914452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.004437703,0.001280676,0.002411965,0.009719348,0.004121009,0.005637711,0.004239223,0.00000315732,0.0002336427,0.0003070065,0.0002447518,0.9673638],"study_design_scores_gemma":[0.01562784,0.002117479,0.0004444773,0.04418517,0.005691123,0.001702671,0.00001216423,0.00002047522,0.00003170506,0.00001889895,0.9296547,0.000493352],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009191417,0.986927,0.000006471731,0.0003207286,0.0003395623,0.001567241,0.0005138315,0.00003666799,0.001097095],"genre_scores_gemma":[0.001515558,0.9942669,0.0001036387,0.0008545641,0.0005574931,0.0001979407,0.001032612,0.00008996714,0.001381389],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9668704,"threshold_uncertainty_score":0.9997306,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3019172665","doi":"10.2147/pgpm.s198225","title":"<p>Challenges and Future Prospects of Precision Medicine in Psychiatry</p>","year":2020,"lang":"en","type":"review","venue":"Pharmacogenomics and Personalized Medicine","topic":"Treatment of Major Depression","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Dalhousie University","funders":"","keywords":"Medicine; Precision medicine; Psychiatry; Pathology","authors":[{"name":"Mirko Manchia","is_ca":true},{"name":"Claudia Pisanu","is_ca":false},{"name":"Alessio Squassina","is_ca":true},{"name":"Bernardo Carpiniello","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.05824669392619478,"gpt":0.3612625721149344,"spread":0.3030158781887396,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008039258,0.001011164,0.004778821,0.0006567721,0.00007650098,0.000007800685,0.0002422177,0.0004833852,0.000448952],"category_scores_gemma":[0.0001423135,0.0006515909,0.0002731298,0.0004208772,0.0005499527,0.0000729211,0.0001759377,0.0007489633,0.000007253607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001673666,"about_ca_system_score_gemma":0.0003547502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001221258,"about_ca_topic_score_gemma":0.00001538387,"domain_scores_codex":[0.9958556,0.0002450178,0.001431246,0.001204365,0.0007923602,0.0004713662],"domain_scores_gemma":[0.9975213,0.000383729,0.0008046336,0.0004546183,0.000118568,0.000717092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008189678,0.0002420855,0.00004754035,0.03151802,0.0006487881,0.0002378295,0.002349124,3.345234e-8,0.001044467,0.001545919,0.003122918,0.9584243],"study_design_scores_gemma":[0.0137696,0.001322037,0.0002399588,0.03391382,0.004969982,0.0007449812,0.0001667254,0.00003219432,0.000008100636,0.0002456244,0.9441518,0.0004351468],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006055367,0.9805018,0.000002995701,0.0120701,0.001116698,0.002529054,0.00007919775,0.00005781419,0.003036827],"genre_scores_gemma":[0.0002812928,0.9939302,0.000629833,0.0003615222,0.003966075,0.0001209218,0.0002763987,0.0001513644,0.0002824065],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9579892,"threshold_uncertainty_score":0.9995936,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2610516495","doi":"10.2147/pgpm.s108123","title":"Thiopurine S-methyltransferase polymorphisms in acute lymphoblastic leukemia, inflammatory bowel disease and autoimmune disorders: influence on treatment response","year":2017,"lang":"en","type":"review","venue":"Pharmacogenomics and Personalized Medicine","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Thiopurine methyltransferase; Pharmacogenetics; Medicine; Pharmacogenomics; Mercaptopurine; Azathioprine; Inflammatory bowel disease; Dosing; Disease; Pharmacology; Bioinformatics; Genotype; Internal medicine; Gene; Genetics; Biology","authors":[{"name":"Rachid Abaji","is_ca":false},{"name":"Maja Krajinović","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.04623696960721095,"gpt":0.3692977215010061,"spread":0.3230607518937952,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001225573,0.001392567,0.003394525,0.001122372,0.000361452,0.00007703167,0.0004433448,0.0004063459,0.0002040902],"category_scores_gemma":[0.0006410374,0.0009768723,0.0004335457,0.0002553733,0.001525105,0.0001547423,0.0002068683,0.0008872412,0.00004128115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003750081,"about_ca_system_score_gemma":0.004981507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004689107,"about_ca_topic_score_gemma":0.00001638986,"domain_scores_codex":[0.995024,0.000541571,0.001283132,0.001404722,0.0007670156,0.0009795668],"domain_scores_gemma":[0.9953106,0.001665349,0.0004611225,0.001023441,0.00009137004,0.001448124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.03534193,0.0005989448,0.0005910182,0.01677122,0.003737328,0.00885446,0.002529191,0.00001301846,0.001793163,0.0001701808,0.0003000128,0.9292995],"study_design_scores_gemma":[0.03771251,0.002350939,0.004004032,0.02835235,0.01003366,0.001113457,0.00005841271,0.001266251,0.00001738999,0.00007557112,0.9137487,0.001266666],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.09124564,0.9034633,0.00001110837,0.001587111,0.0002216518,0.002849081,0.0004165938,0.00006824599,0.0001372586],"genre_scores_gemma":[0.006199784,0.9894177,0.00005186351,0.0006288093,0.0004132084,0.0005861017,0.0003226326,0.000211777,0.002168105],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9280329,"threshold_uncertainty_score":0.9998825,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2149270596","doi":"10.2147/pgpm.s55339","title":"Toward precision medicine with next-generation EGFR inhibitors in non-small-cell lung cancer","year":2014,"lang":"en","type":"review","venue":"Pharmacogenomics and Personalized Medicine","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Cancer Research","funders":"Academy of Medical Sciences; National Institute for Health and Care Research; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research","keywords":"Afatinib; Medicine; Epidermal growth factor receptor; T790M; Lung cancer; Adenocarcinoma; EGFR inhibitors; Precision medicine; Drug resistance; Oncology; Targeted therapy; Osimertinib; Cancer research; Gefitinib; Cancer; Erlotinib; Internal medicine; Pathology; Biology","authors":[{"name":"Sanjay Popat","is_ca":false},{"name":"Timothy A. Yap","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.09332858321314516,"gpt":0.4054736549770533,"spread":0.3121450717639082,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005608544,0.0007819833,0.002735317,0.0005639833,0.000132036,0.00002539714,0.0001471085,0.0002650924,0.0006455089],"category_scores_gemma":[0.00003425345,0.0004700743,0.0001828276,0.0004917136,0.0002600049,0.00008463065,0.00005080537,0.0005769214,0.000006734272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007088275,"about_ca_system_score_gemma":0.0007426176,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001043009,"about_ca_topic_score_gemma":0.00009416018,"domain_scores_codex":[0.9970759,0.0001318284,0.001005405,0.0008754138,0.0004520108,0.0004594219],"domain_scores_gemma":[0.9983047,0.0002147039,0.0005284856,0.0002970976,0.0001674518,0.0004876225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002941176,0.0002021499,0.0004209508,0.02922068,0.001144237,0.0001933652,0.005254408,0.000009559293,0.000863763,0.000044988,0.01046736,0.9518844],"study_design_scores_gemma":[0.01359743,0.000621336,0.00001570605,0.03054632,0.01261391,0.0001909336,0.0002292529,0.001318252,0.0000255058,0.000005465076,0.9403378,0.0004980691],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001973112,0.990154,0.0002374644,0.001778681,0.0007847234,0.003086221,0.00006203818,0.00003413952,0.00188961],"genre_scores_gemma":[0.001640731,0.9899992,0.0003062099,0.001078929,0.003446484,0.0006886195,0.001039807,0.0001403217,0.001659739],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9513863,"threshold_uncertainty_score":0.9997751,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4285744210","doi":"10.2147/pgpm.s350205","title":"The Impact of Pharmacogenetics on Pharmacokinetics and Pharmacodynamics in Neonates and Infants: A Systematic Review","year":2022,"lang":"en","type":"review","venue":"Pharmacogenomics and Personalized Medicine","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"Türkiye Bilimsel ve Teknolojik Araştırma Kurumu; Erasmus Medisch Centrum","keywords":"Medicine; Pharmacogenetics; Pharmacokinetics; Pharmacodynamics; Pharmacology; Intensive care medicine; Genotype; Genetics","authors":[{"name":"Nadir Yalçın","is_ca":false},{"name":"Robert B. Flint","is_ca":false},{"name":"Ron HN van Schaik","is_ca":false},{"name":"Sinno H. P. Simons","is_ca":false},{"name":"Karel Allegaert","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.1050325271801629,"gpt":0.4671641786844816,"spread":0.3621316515043186,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00239929,0.0008906125,0.004261525,0.0002943937,0.0003120362,0.00003131835,0.0002829233,0.0001205591,0.0004782538],"category_scores_gemma":[0.0005600171,0.0005034261,0.0004045188,0.0005748653,0.0007765843,0.00005804197,0.000355648,0.001336698,0.00000177677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000229016,"about_ca_system_score_gemma":0.0002389537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008530723,"about_ca_topic_score_gemma":0.000001467621,"domain_scores_codex":[0.9957242,0.0007319907,0.001709618,0.0006889159,0.0005667217,0.0005785687],"domain_scores_gemma":[0.9941103,0.003898192,0.001067084,0.0003065974,0.0000933754,0.0005244459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006715718,0.000217428,0.00003821467,0.6771211,0.003315432,0.0001420147,0.0004320267,0.000001304061,0.0000730145,0.00007268706,0.0008384876,0.3170767],"study_design_scores_gemma":[0.005473226,0.0006978671,0.000008187769,0.1416068,0.01990267,0.001119093,0.0001350484,0.001602518,0.000003334909,0.00002799478,0.8288961,0.0005271994],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006819268,0.9930029,0.000001136196,0.001012369,0.0002142738,0.004246849,0.0002789943,0.00001971049,0.0005418733],"genre_scores_gemma":[0.0003362896,0.9970314,0.00002014566,0.001711826,0.0001983513,0.0003892899,0.00008902469,0.00009946126,0.000124245],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8280576,"threshold_uncertainty_score":0.9997417,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2068587561","doi":"10.2147/pgpm.s6969","title":"The molecular mechanisms and pharmacotherapy of ATP-sensitive potassium channel gene mutations underlying neonatal diabetes","year":2010,"lang":"en","type":"article","venue":"Pharmacogenomics and Personalized Medicine","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"","keywords":"Sulfonylurea receptor; Kir6.2; Potassium channel; Medicine; Insulin; Congenital hyperinsulinism; Adenosine triphosphate; Diabetes mellitus; Endocrinology; Internal medicine; Hyperinsulinism; Pharmacology; Mutation; Gene; Biology; Biochemistry; Insulin resistance; Glibenclamide; Protein subunit","authors":[{"name":"Peter E. Light","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02423750078510637,"gpt":0.3027909313417508,"spread":0.2785534305566444,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004415651,0.0002051443,0.0003798122,0.0001024243,0.0002367957,0.00001545055,0.00005610313,0.00006199052,0.0001352836],"category_scores_gemma":[0.00008822345,0.000139512,0.0000669505,0.0001251736,0.0005962765,0.00004352871,0.00002837085,0.0002546571,0.000001745208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000152778,"about_ca_system_score_gemma":0.00006593611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003126257,"about_ca_topic_score_gemma":0.000001421905,"domain_scores_codex":[0.9989209,0.00004567051,0.0002799867,0.0002596088,0.0002260966,0.0002677969],"domain_scores_gemma":[0.9989485,0.000362054,0.0001330535,0.0001294489,0.0001439793,0.0002830254],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002168343,0.00003427325,0.0001850609,0.0000583159,0.0003090081,0.00001503227,0.001652276,0.000001638111,0.9874793,0.002618407,0.00008259251,0.007347288],"study_design_scores_gemma":[0.01458388,0.000505951,0.001341374,0.0001058219,0.001214272,0.0002194689,0.002354037,0.01753139,0.944262,0.003084767,0.01445726,0.0003398191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840438,0.00684566,0.001413572,0.006330212,0.0004401636,0.0004153694,0.00005208177,0.00003032184,0.0004287904],"genre_scores_gemma":[0.9925116,0.002379234,0.001126072,0.003450983,0.000192968,0.00002939184,0.00006438977,0.00003252339,0.0002128657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04321731,"threshold_uncertainty_score":0.5689136,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4285684482","doi":"10.2147/pgpm.s348851","title":"The Efficacy of a Didactic and Case-Based Pharmacogenomics Education Program on Improving the Knowledge and Confidence of Alberta Pharmacists","year":2022,"lang":"en","type":"article","venue":"Pharmacogenomics and Personalized Medicine","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"Saskatchewan Health; University of Alberta","funders":"","keywords":"Pharmacogenomics; Likert scale; Medicine; Pharmacy; Medical education; Scale (ratio); Family medicine; Pharmacology; Psychology","authors":[{"name":"Meagan Hayashi","is_ca":true},{"name":"Sherif Hanafy Mahmoud","is_ca":true},{"name":"Dalia A. Hamdy","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.08072898205224215,"gpt":0.4376568478287824,"spread":0.3569278657765403,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002370441,0.0003968576,0.0005331884,0.0001752361,0.001259005,0.00002728111,0.0003841408,0.00007924081,0.0003437551],"category_scores_gemma":[0.0001654819,0.0002752679,0.0001047747,0.0003192223,0.001578051,0.00005245514,0.0002890963,0.0008870778,0.000001300432],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006119118,"about_ca_system_score_gemma":0.0004071706,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000234179,"about_ca_topic_score_gemma":0.00001153372,"domain_scores_codex":[0.997137,0.0008730436,0.0007309678,0.0005181761,0.0002778805,0.0004630029],"domain_scores_gemma":[0.9950182,0.003576531,0.000592043,0.0002550832,0.0001781761,0.0003799526],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00408289,0.001373815,0.0008585209,0.0004438395,0.000616707,0.00005629409,0.01009996,0.0001872511,0.3474207,0.00359111,0.001539578,0.6297294],"study_design_scores_gemma":[0.02201132,0.001059417,0.0005768792,0.00005910696,0.003084749,0.002165228,0.002483107,0.06785382,0.05654042,0.0004760492,0.8429847,0.0007051391],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9329267,0.05995601,0.00001650567,0.002672395,0.001328125,0.002011263,0.0001371161,0.00002231052,0.0009295808],"genre_scores_gemma":[0.983382,0.01288929,0.00007625932,0.002428173,0.0003747967,0.0004488482,0.00002667573,0.00004780169,0.0003261443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8414452,"threshold_uncertainty_score":0.99997,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4360862235","doi":"10.2147/pgpm.s383221","title":"Current Understanding of Inherited Modifiers of FVIII Pharmacokinetic Variation","year":2023,"lang":"en","type":"review","venue":"Pharmacogenomics and Personalized Medicine","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Queen's University","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Medicine; Von Willebrand factor; Coagulation; Pharmacokinetics; ABO blood group system; Immunology; Dosing; Internal medicine; Pharmacology; Platelet","authors":[{"name":"Laura L. Swystun","is_ca":true},{"name":"David Lillicrap","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.3865463992255132,"gpt":0.4805211672046102,"spread":0.09397476797909704,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007481439,0.0004204192,0.002373212,0.0007729777,0.00006641632,0.00000518894,0.0001336982,0.0001663493,0.0003601822],"category_scores_gemma":[0.00008484469,0.0002949043,0.0003536052,0.000735414,0.0004597641,0.00002908836,0.00007543894,0.0004613981,0.0000075274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002684033,"about_ca_system_score_gemma":0.000420448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004419125,"about_ca_topic_score_gemma":4.222165e-7,"domain_scores_codex":[0.9975566,0.0001545884,0.000993522,0.000422862,0.0005386163,0.0003338563],"domain_scores_gemma":[0.9984221,0.0004016083,0.0005178989,0.0002010064,0.0001351648,0.0003222384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006782275,0.0003773509,0.00005938912,0.1611608,0.004182913,0.0001022104,0.002627196,0.000001562703,0.004371292,0.001145332,0.00178517,0.8235086],"study_design_scores_gemma":[0.01073584,0.0005126052,0.00002016226,0.03534027,0.01332328,0.0001201345,0.0002703046,0.001201652,0.00006255302,0.0003120119,0.9376755,0.0004257391],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000605072,0.9964148,0.00012845,0.0002631888,0.0004565658,0.001521809,0.0001721089,0.00003278504,0.0004051768],"genre_scores_gemma":[0.001059996,0.997409,0.00005355942,0.00002905723,0.0004608794,0.00005550406,0.0004350014,0.00008548614,0.0004115526],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9358903,"threshold_uncertainty_score":0.9999503,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2936175924","doi":"10.2147/pgpm.s192924","title":"<p>Identification of genetic variants associated with skeletal muscle function deficit in childhood acute lymphoblastic leukemia survivors</p>","year":2019,"lang":"en","type":"article","venue":"Pharmacogenomics and Personalized Medicine","topic":"Childhood Cancer Survivors' Quality of Life","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true},"ca_institutions":"Shriners Hospitals for Children - Canada; Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; C17 Council; Cancer Research Society; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Medicine; Lymphoblastic Leukemia; Identification (biology); Skeletal muscle; Internal medicine; Pediatrics; Leukemia","authors":[{"name":"Geneviève Nadeau","is_ca":true},{"name":"Erika Ouimet-Grennan","is_ca":true},{"name":"Michelle Aaron","is_ca":true},{"name":"Simon Drouin","is_ca":true},{"name":"Laurence Bertout","is_ca":true},{"name":"Albert Shalmiev","is_ca":true},{"name":"Patrick Beaulieu","is_ca":true},{"name":"Pascal St-Onge","is_ca":true},{"name":"Louis‐Nicolas Veilleux","is_ca":true},{"name":"Frank Rauch","is_ca":true},{"name":"Kateryna Petrykey","is_ca":true},{"name":"Caroline Laverdière","is_ca":true},{"name":"Daniel Sinnett","is_ca":true},{"name":"Nathalie Alos","is_ca":true},{"name":"Maja Krajinović","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.0144881469483887,"gpt":0.2659002123683694,"spread":0.2514120654199807,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001243985,0.0004228133,0.001051328,0.0003728177,0.00008941187,0.00001919127,0.0001680811,0.0001708925,0.0005521806],"category_scores_gemma":[0.0001821986,0.0003700635,0.0001247544,0.0006007905,0.0002665533,0.0001249547,0.00005536856,0.0002865715,0.00002660731],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004202974,"about_ca_system_score_gemma":0.0004815188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003704714,"about_ca_topic_score_gemma":0.0003139963,"domain_scores_codex":[0.9967173,0.0002135696,0.001076309,0.000723725,0.0007826464,0.0004864202],"domain_scores_gemma":[0.9980961,0.0003391404,0.0006307409,0.0003820419,0.0002384635,0.0003134951],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003116688,0.001078286,0.07804389,0.000921829,0.00247625,0.0001037449,0.01262217,0.0002926529,0.8911545,0.0005910206,0.0004791815,0.00911981],"study_design_scores_gemma":[0.02778059,0.001279294,0.9578983,0.0009163549,0.001972004,0.000144285,0.0003968168,0.006036563,0.0007656143,0.0001583462,0.002124642,0.000527174],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925309,0.003876455,0.000498882,0.000725096,0.0005619819,0.001065923,0.0001242072,0.00005921075,0.0005572858],"genre_scores_gemma":[0.9958903,0.001877219,0.0001194012,0.0008734533,0.0003104122,0.00003649651,0.000337005,0.00008370036,0.0004719964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8903888,"threshold_uncertainty_score":0.9998751,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3068359420","doi":"10.2147/pgpm.s261208","title":"<p>IL-6 −572C>G and CARD8 304T>A Genetic Polymorphisms are Associated with the Absolute Neutrophil Count in Patients with Hematological Malignancies Under Chemotherapy: An Application of Multilevel Models to a Preliminary Pharmacogenetic Study</p>","year":2020,"lang":"en","type":"article","venue":"Pharmacogenomics and Personalized Medicine","topic":"Inflammatory Biomarkers in Disease Prognosis","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Impact; McMaster University; Population Health Research Institute","funders":"Universidad de Chile","keywords":"Medicine; Internal medicine; Gastroenterology; Chemotherapy; Absolute neutrophil count; Genotype; Neutropenia; Oncology; Acute leukemia; Leukemia; Gene","authors":[{"name":"Matías F. Martínez","is_ca":false},{"name":"Enzo Alveal","is_ca":false},{"name":"Tomas G. Soto","is_ca":false},{"name":"Eva Bustamante","is_ca":false},{"name":"Fernanda Gobbi de Ávila","is_ca":false},{"name":"Shrikant I. Bangdiwala","is_ca":true},{"name":"Ivonne I. Flores","is_ca":false},{"name":"Claudia Benavides","is_ca":false},{"name":"Ricardo Morales","is_ca":false},{"name":"Nelson Varela","is_ca":false},{"name":"Luis A. Quiñones","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.03032901294697899,"gpt":0.2638131900072627,"spread":0.2334841770602837,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004112449,0.0005177158,0.0009425462,0.00015444,0.0001614209,0.00002101464,0.0002411139,0.0001138227,0.00005399168],"category_scores_gemma":[0.00002411322,0.0003385606,0.00006618007,0.0003625559,0.0005310863,0.0000825215,0.0001037558,0.0002144947,0.000001290363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001292127,"about_ca_system_score_gemma":0.000138467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002208817,"about_ca_topic_score_gemma":0.00001839131,"domain_scores_codex":[0.9971894,0.0001945329,0.0006001617,0.0008040635,0.0007429469,0.0004688977],"domain_scores_gemma":[0.9982734,0.0001311238,0.0003955484,0.0003008815,0.0003131441,0.0005859506],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.06864996,0.004802083,0.4837293,0.00121642,0.003991921,0.0004661737,0.03865047,0.002093137,0.3842098,0.0001620165,0.001215432,0.01081323],"study_design_scores_gemma":[0.03862967,0.004356605,0.8971392,0.0004198802,0.002295043,0.00005334454,0.001170549,0.05324709,0.001246064,0.00003898353,0.0007127658,0.0006908114],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874573,0.004237855,0.0005650597,0.003936405,0.00003605727,0.003489806,0.0002016251,0.00005198072,0.00002393975],"genre_scores_gemma":[0.9934799,0.0005660822,0.0004510179,0.00480902,0.0001182487,0.0003828334,0.00008975634,0.00008992483,0.00001322907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4134099,"threshold_uncertainty_score":0.9999067,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4406928370","doi":"10.2147/pgpm.s490135","title":"Pharmacogenomics Tools for Precision Public Health and Lessons for Low- and Middle-Income Countries: A Scoping Review","year":2025,"lang":"en","type":"review","venue":"Pharmacogenomics and Personalized Medicine","topic":"Computational Drug Discovery Methods","field":"Computer Science","cited_by":5,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true},"ca_institutions":"","funders":"","keywords":"Medicine; Pharmacogenomics; Low and middle income countries; Public health; Precision medicine; Developing country; Pharmacology; Economic growth; Nursing; Pathology","authors":[{"name":"Angélica Borbón","is_ca":false},{"name":"Juan Carlos Briceño Triana","is_ca":false},{"name":"Augusto Valderrama-Aguirre","is_ca":false}],"retraction":null,"screen_n_in":null,"score":{"opus":0.2597879676768023,"gpt":0.4950694151345046,"spread":0.2352814474577023,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00480564,0.0007143872,0.003061011,0.0004286376,0.0004956432,0.0003492346,0.0006791973,0.0001399255,0.00001475463],"category_scores_gemma":[0.001051854,0.0006023297,0.0003064726,0.0004327013,0.0002619014,0.0004593499,0.0005241735,0.0002968667,7.780564e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002470185,"about_ca_system_score_gemma":0.003065309,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007410696,"about_ca_topic_score_gemma":0.000001906676,"domain_scores_codex":[0.9957905,0.0004866733,0.001428954,0.001298503,0.0003306727,0.000664707],"domain_scores_gemma":[0.9890522,0.008732161,0.000892372,0.0003605057,0.0002825089,0.0006802342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002979583,0.0000173897,2.43598e-7,0.3310927,0.0001854532,0.000001771762,0.0003749306,0.000001002942,8.51317e-7,0.006028471,0.0003324929,0.6619349],"study_design_scores_gemma":[0.002335916,0.0001323402,1.833501e-7,0.3050263,0.0005950424,0.00009821336,0.00001787237,0.004841038,7.574888e-7,0.0006093294,0.6859084,0.0004346701],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000006547384,0.8438909,0.138627,0.009431005,0.0006074818,0.006717786,0.0006487627,0.00004768189,0.00002287868],"genre_scores_gemma":[0.000001174349,0.9651345,0.02664615,0.006252013,0.0004162682,0.001070253,0.0003212809,0.0000550431,0.0001033418],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6855759,"threshold_uncertainty_score":0.9996428,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4403836480","doi":"10.2147/pgpm.s481068","title":"Pharmacogenomic Study of Selected Genes Affecting Amlodipine Blood Pressure Response in Patients with Hypertension","year":2024,"lang":"en","type":"article","venue":"Pharmacogenomics and Personalized Medicine","topic":"Renin-Angiotensin System Studies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto; Université de Moncton; Centre for Addiction and Mental Health","funders":"King Saud University","keywords":"Medicine; Amlodipine; Pharmacogenomics; Blood pressure; Internal medicine; Pharmacology; Cardiology","authors":[{"name":"Asif Jan","is_ca":false},{"name":"Abdullah R. Alanzi","is_ca":false},{"name":"Ramzi A. Mothana","is_ca":false},{"name":"Jun-Ya Kaimori","is_ca":false},{"name":"Syed Shaukat Ali","is_ca":false},{"name":"Tahir Muhammad","is_ca":true},{"name":"Muhammad Saeed","is_ca":false},{"name":"Rani Akbar","is_ca":false},{"name":"Mehtab Khan","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02188692059917152,"gpt":0.2905835502866367,"spread":0.2686966296874652,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007822019,0.0003809815,0.001013489,0.0005001936,0.00009508331,0.00001448018,0.00008402421,0.00006963131,0.00008199018],"category_scores_gemma":[0.000121987,0.000260755,0.00006097415,0.0007095501,0.0001764039,0.00006765777,0.00007112609,0.000303147,0.000002442684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004771824,"about_ca_system_score_gemma":0.0001261864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001776696,"about_ca_topic_score_gemma":0.000006988121,"domain_scores_codex":[0.9976858,0.0002765097,0.0005975519,0.0006227558,0.0004631749,0.0003541412],"domain_scores_gemma":[0.9986876,0.0004060112,0.0001491102,0.0002072978,0.0003574615,0.0001924698],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.02751495,0.001252537,0.4128321,0.0006503748,0.004291666,0.0005701099,0.01440537,0.000034178,0.5340486,0.000002975964,0.0003810502,0.004016135],"study_design_scores_gemma":[0.08360522,0.01132649,0.8677944,0.002497665,0.01467373,0.0005694922,0.002161792,0.003408787,0.008183851,0.000003219272,0.005060135,0.0007152155],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9576344,0.03955998,0.000005790238,0.0005685032,0.0002693383,0.001811386,0.00002880608,0.000075573,0.00004618549],"genre_scores_gemma":[0.9980171,0.00109289,0.000124441,0.0001537829,0.000285887,0.00003444583,0.00003042087,0.00007839745,0.0001826892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5258648,"threshold_uncertainty_score":0.9999844,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4308454158","doi":"10.2147/pgpm.s385272","title":"Utilizing Pharmacogenomics Results to Determine Opioid Appropriateness and Improve Pain Management in a Patient with Osteoarthritis","year":2022,"lang":"en","type":"article","venue":"Pharmacogenomics and Personalized Medicine","topic":"Pain Management and Opioid Use","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"","keywords":"Medicine; Pharmacogenomics; Opioid; Pharmacogenetics; Adverse effect; Celecoxib; Intensive care medicine; Osteoarthritis; Pharmacotherapy; Physical therapy; Alternative medicine; Pharmacology; Internal medicine","authors":[{"name":"Katie Pizzolato","is_ca":false},{"name":"David Thacker","is_ca":false},{"name":"Nicole Marie Del Toro-Pagán","is_ca":false},{"name":"Nishita Shah Amin","is_ca":false},{"name":"Abeer Hanna","is_ca":false},{"name":"Jacques Turgeon","is_ca":true},{"name":"Véronique Michaud","is_ca":true}],"retraction":null,"screen_n_in":null,"score":{"opus":0.02345495770120698,"gpt":0.2745070678679702,"spread":0.2510521101667633,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001539178,0.0003464346,0.0005527447,0.000439841,0.0002449856,0.00002479944,0.000132577,0.00003186881,0.0001355855],"category_scores_gemma":[0.00003623665,0.0003012225,0.0000451797,0.0003892877,0.0001389736,0.00005530149,0.0003476238,0.0003160166,0.000001825262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001808311,"about_ca_system_score_gemma":0.00004735134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001226481,"about_ca_topic_score_gemma":0.00001430921,"domain_scores_codex":[0.9976413,0.000173611,0.000537064,0.0007290532,0.0004206937,0.0004982863],"domain_scores_gemma":[0.9990423,0.0001238778,0.0001484156,0.0002299126,0.00004696135,0.0004085243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.02589104,0.0005072387,0.007282886,0.001171086,0.000596976,0.004846456,0.02125262,0.0001079383,0.1054574,0.0004000784,0.001877463,0.8306088],"study_design_scores_gemma":[0.1245339,0.009828236,0.006729393,0.000842986,0.001767721,0.0006819691,0.02970196,0.02541515,0.002589317,0.0002970992,0.79576,0.001852283],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879685,0.004035166,0.0001593251,0.003597312,0.0002314572,0.002345816,0.00009934113,0.00004643788,0.001516631],"genre_scores_gemma":[0.9824515,0.0036923,0.002138508,0.01021916,0.0002190857,0.0005134658,0.000153677,0.00006748089,0.000544819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8287566,"threshold_uncertainty_score":0.999944,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}