{"meta":{"page":1,"per_page":50,"max_per_page":100,"total":81,"total_is_capped":false,"direct_labels_cover":0,"predictions_cover":81,"direct_label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline (scores rank; they never assert a category)","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"query_hash":"54dce2eeb2fa","filters":{"venue":"Signal Transduction and Targeted Therapy"}},"results":[{"id":"W3142080073","doi":"10.1038/s41392-021-00507-5","title":"Pyroptosis: mechanisms and diseases","year":2021,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2308,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SKiN Health","funders":"Project 211; Higher Education Discipline Innovation Project; National Natural Science Foundation of China","keywords":"Pyroptosis; Medicine; Immunology; Inflammasome; Inflammation","retraction":null,"screen_n_in":null,"score":{"opus":0.01677021942760649,"gpt":0.2687090103631539,"spread":0.2519387909355474,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006526936,0.0003127433,0.0005435246,0.00006620964,0.0001215297,0.0000465966,0.00007323386,0.0002691226,0.0002085533],"category_scores_gemma":[0.000004069535,0.0002612272,0.000268269,0.0001001774,0.00008041267,0.000005499046,0.00001657864,0.0001342731,0.000002366654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004357015,"about_ca_system_score_gemma":0.00008726412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003058346,"about_ca_topic_score_gemma":9.190243e-7,"domain_scores_codex":[0.9989192,0.0001360902,0.0002397673,0.0004350544,0.00008524099,0.0001846771],"domain_scores_gemma":[0.9996284,0.000007110664,0.00007702105,0.0001698301,0.00004197246,0.00007567386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000337092,0.00005509951,0.000001419934,0.0006689975,0.0004649835,0.000002689836,0.0000383243,4.947605e-7,0.008028551,0.0002044364,0.0001322799,0.990369],"study_design_scores_gemma":[0.0004567213,0.0002184348,0.000004204803,0.000398082,0.0001935424,0.00003284701,0.00009338863,7.466947e-7,0.004115161,0.0001377458,0.9940013,0.0003477739],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003070452,0.9984177,0.0006525572,0.00002917351,0.000176474,0.0002940682,0.00005470728,0.00001750627,0.00005073003],"genre_scores_gemma":[0.0005396699,0.997911,0.00009965737,0.00009266848,0.0001566734,0.00007047439,0.0008715385,0.00004529174,0.0002130002],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9938691,"threshold_uncertainty_score":0.999984,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3035408975","doi":"10.1038/s41392-020-0187-x","title":"The mechanisms of sorafenib resistance in hepatocellular carcinoma: theoretical basis and therapeutic aspects","year":2020,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":1132,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McMaster University","funders":"","keywords":"Sorafenib; Hepatocellular carcinoma; Resistance (ecology); Medicine; Oncology; Bioinformatics; Internal medicine; Cancer research; Computational biology; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.05311660016790334,"gpt":0.2674391736520976,"spread":0.2143225734841942,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004019548,0.0004861525,0.001438981,0.0001731324,0.0001492085,0.00003574887,0.0001113726,0.0003189012,0.0002017276],"category_scores_gemma":[0.00001006298,0.0003014674,0.000407952,0.0004836381,0.0004060756,0.00003571783,0.00001218003,0.0004901107,0.000003268657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005104807,"about_ca_system_score_gemma":0.0002035778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001208475,"about_ca_topic_score_gemma":0.000006079937,"domain_scores_codex":[0.9977271,0.0004676162,0.000636398,0.0005438469,0.0003098916,0.000315177],"domain_scores_gemma":[0.9990881,0.0002424416,0.0001763716,0.0002544208,0.0000596366,0.0001790383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001131135,0.0002758131,0.001406289,0.004965956,0.001032131,0.0002999823,0.0009018878,2.141599e-8,0.0008500286,0.09141394,0.00001029939,0.8977125],"study_design_scores_gemma":[0.008284951,0.002678805,0.0005172527,0.005433303,0.003787639,0.0003450739,0.000431391,0.000500362,0.01338042,0.07384063,0.8893759,0.001424256],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003159391,0.9937254,0.0002792071,0.00076883,0.00009018378,0.001699863,0.00002879729,0.00003821407,0.0002100668],"genre_scores_gemma":[0.3958434,0.6037465,0.0001171821,0.00003964747,0.0000546272,0.0000950509,0.00003142935,0.00004373865,0.00002836546],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8962883,"threshold_uncertainty_score":0.9999437,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4382601497","doi":"10.1038/s41392-023-01484-7","title":"Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future","year":2023,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":887,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"National Natural Science Foundation of China","keywords":"Senile plaques; Amyloid β; Disease; Clinical trial; Biochemistry of Alzheimer's disease; Alzheimer's disease; Medicine; Amyloid (mycology); Drug development; Neuroscience; Bioinformatics; Psychology; Amyloid precursor protein; Pathology; Psychiatry; Drug; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.1223737716968342,"gpt":0.3752099604563784,"spread":0.2528361887595442,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002214072,0.0006931585,0.001376092,0.0003754016,0.0002828756,0.00006809377,0.0001089974,0.0003242301,0.0003654784],"category_scores_gemma":[0.000005355038,0.0004821169,0.0006162263,0.0003376949,0.0001984196,0.000114013,0.000007454388,0.0003413776,0.00001483986],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003521844,"about_ca_system_score_gemma":0.0006203164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001313367,"about_ca_topic_score_gemma":0.000002709582,"domain_scores_codex":[0.9975507,0.0002085335,0.0004406171,0.0008573103,0.0004269681,0.0005158767],"domain_scores_gemma":[0.9984321,0.0001984577,0.0001473571,0.0003293277,0.0001499403,0.0007428098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001869496,0.0004981571,0.0000124415,0.0055365,0.01329945,0.00005867672,0.0000550408,1.732659e-7,0.000002910958,0.0001575441,0.0001845705,0.978325],"study_design_scores_gemma":[0.005120868,0.001102958,0.0002437647,0.001837808,0.002879475,0.00002418998,0.00005642274,0.00001226606,0.00004041191,0.0003174873,0.9878805,0.0004838847],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000580728,0.9929276,0.00002180898,0.001819311,0.0002398354,0.004017038,0.0006535024,0.0002323103,0.00003059885],"genre_scores_gemma":[0.0005342725,0.9946244,0.00008761034,0.0001160119,0.001307353,0.001293158,0.001812865,0.0001821577,0.00004217468],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9876959,"threshold_uncertainty_score":0.9997631,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4385828734","doi":"10.1038/s41392-023-01503-7","title":"The mitophagy pathway and its implications in human diseases","year":2023,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":768,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"Servier; Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"Mitophagy; Computational biology; Biology; Medicine; Genetics; Autophagy","retraction":null,"screen_n_in":null,"score":{"opus":0.07304080255075136,"gpt":0.3605082258097838,"spread":0.2874674232590324,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001589985,0.0003519104,0.0007982129,0.0002167987,0.0003758154,0.000051015,0.0001051026,0.0002049823,0.0001540323],"category_scores_gemma":[0.000008252869,0.0002242548,0.0002788161,0.0004521796,0.0001336611,0.00006717663,0.000009462329,0.0003506101,0.00001317017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003462124,"about_ca_system_score_gemma":0.0001581961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008396344,"about_ca_topic_score_gemma":0.000004966821,"domain_scores_codex":[0.9984521,0.0001792713,0.0004836645,0.0004405956,0.0001626637,0.0002817166],"domain_scores_gemma":[0.9992231,0.0001644134,0.0001239455,0.0002460967,0.0000467135,0.0001957452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009557101,0.0001925485,0.00002988743,0.001905371,0.000535818,0.00002581173,0.0001621851,2.665541e-7,0.0004828752,0.003386339,0.00008033674,0.993103],"study_design_scores_gemma":[0.001885329,0.0003019677,0.0025104,0.002051713,0.0003552568,0.0000781236,0.0000689521,0.000006596615,0.0002591334,0.003698578,0.9883745,0.0004095011],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002877596,0.9950284,0.000007558473,0.000292818,0.0001422365,0.001330239,0.0001363061,0.0001297741,0.00005506568],"genre_scores_gemma":[0.004991411,0.9931504,0.000003430833,0.00009572041,0.0003232475,0.0004336402,0.0002478945,0.00007356358,0.0006807316],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9926935,"threshold_uncertainty_score":0.9144846,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4392757206","doi":"10.1038/s41392-024-01769-5","title":"Ferroptosis in cancer: from molecular mechanisms to therapeutic strategies","year":2024,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Ferroptosis and cancer prognosis","field":"Medicine","cited_by":714,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SKiN Health","funders":"National Natural Science Foundation of China","keywords":"Cancer; Cancer research; Cancer cell; Tumor microenvironment; Immunotherapy; Biology; Immunology; Medicine; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.06071929866109995,"gpt":0.3572479687472279,"spread":0.2965286700861279,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001637887,0.0005969284,0.001552315,0.000468921,0.0000539502,0.0001189564,0.000125965,0.0003758182,0.001566104],"category_scores_gemma":[0.000001286063,0.0004333495,0.0004967786,0.0008244067,0.00005017851,0.00008717802,0.00001188771,0.0006098326,0.00003288794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001518417,"about_ca_system_score_gemma":0.0004167183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004644294,"about_ca_topic_score_gemma":0.00004164707,"domain_scores_codex":[0.9977535,0.0001635645,0.0005958783,0.0007952039,0.0003405647,0.0003512705],"domain_scores_gemma":[0.9993857,0.00002520856,0.00008820347,0.0002511511,0.00005371386,0.000196037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001499145,0.0001609258,0.000001815942,0.002621029,0.001031323,0.00003678013,0.000491256,0.000007108313,0.004159709,0.0007730231,0.00007185095,0.9904953],"study_design_scores_gemma":[0.001344996,0.001080421,0.00003047802,0.01513964,0.002668638,0.00003727245,0.0006082806,0.00003055346,0.00454801,0.003890999,0.9696568,0.0009638623],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007616188,0.9942846,0.001179581,0.0009937709,0.0005362791,0.001866745,0.0001423035,0.0001284681,0.0001066629],"genre_scores_gemma":[0.01286069,0.9844264,0.0003006043,0.0005909361,0.000249547,0.001237714,0.0001310181,0.0001285008,0.00007456715],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9895314,"threshold_uncertainty_score":0.9998118,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3182774911","doi":"10.1038/s41392-021-00679-0","title":"The signal pathways and treatment of cytokine storm in COVID-19","year":2021,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":608,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Infection and Immunity","funders":"Versus Arthritis; Servier; National Natural Science Foundation of China","keywords":"Cytokine storm; Immunology; Cytokine; Medicine; Cytokine release syndrome; Immune system; Neutrophilia; Disease; Population; Macrophage activation syndrome; Proinflammatory cytokine; ARDS; Pathogenesis; Inflammation; Infectious disease (medical specialty); Immunotherapy; Lung; Pathology; Coronavirus disease 2019 (COVID-19); Internal medicine; Arthritis","retraction":null,"screen_n_in":null,"score":{"opus":0.1434936055571709,"gpt":0.4293561333629024,"spread":0.2858625278057315,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006647761,0.0003859857,0.001745223,0.0002141183,0.0001936799,0.00002928586,0.00007794844,0.0002275796,0.0003135541],"category_scores_gemma":[0.0003974733,0.0002168849,0.0004328184,0.0004581002,0.0004569487,0.00004265603,0.00001661773,0.0003803578,0.000001344959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002782976,"about_ca_system_score_gemma":0.001115886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001796995,"about_ca_topic_score_gemma":0.00007563313,"domain_scores_codex":[0.9975756,0.0004618004,0.0007370654,0.0005212814,0.0003883853,0.0003158622],"domain_scores_gemma":[0.9958439,0.003324703,0.0001703013,0.0002494948,0.0001025567,0.0003090053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004453096,0.0003772118,0.00007265886,0.003051722,0.000694434,0.00006479336,0.0006028954,0.000002555971,0.0001589647,0.0001128298,0.00002256805,0.9943941],"study_design_scores_gemma":[0.003326813,0.001930964,0.00009604899,0.001659544,0.0002620068,0.00001961993,0.0001761306,0.00001322763,0.00008467244,0.0001482301,0.9920971,0.0001856677],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005740519,0.9963071,0.0001457861,0.001370268,0.00008504786,0.001381201,0.0000915565,0.0000271177,0.00001781792],"genre_scores_gemma":[0.003931444,0.9952245,0.00003797694,0.00016495,0.0002059989,0.0002028007,0.00008556978,0.00003291837,0.000113796],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9942084,"threshold_uncertainty_score":0.8844308,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3160668788","doi":"10.1038/s41392-021-00569-5","title":"Targeting circular RNAs as a therapeutic approach: current strategies and challenges","year":2021,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Circular RNAs in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":561,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto; Sunnybrook Hospital","funders":"Canadian Institutes of Health Research","keywords":"Circular RNA; Gene knockdown; Computational biology; Biology; RNA interference; Microvesicles; Function (biology); Exosome; Bioinformatics; microRNA; RNA; Cell biology; Gene; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.08003431253310524,"gpt":0.321686253947653,"spread":0.2416519414145478,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000235864,0.0005670142,0.0008494873,0.0001108502,0.0001710881,0.0001647431,0.0001687527,0.0003753547,0.00009551996],"category_scores_gemma":[0.00001120174,0.0004935506,0.0004173646,0.0001388673,0.0001955271,0.00001814838,0.00003231318,0.0003359677,0.00000230518],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001551423,"about_ca_system_score_gemma":0.0003186771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004426808,"about_ca_topic_score_gemma":5.332939e-7,"domain_scores_codex":[0.9976745,0.0004555244,0.0004011454,0.0009232612,0.000221754,0.0003237916],"domain_scores_gemma":[0.999253,0.00002117841,0.0001674997,0.0003180292,0.00008335686,0.0001569838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002500425,0.0001701281,0.00000123591,0.004083822,0.0007614483,0.000006629874,0.0001462228,0.000006274257,0.002950126,0.0007156838,0.00001667182,0.9911168],"study_design_scores_gemma":[0.0004819782,0.0001655664,0.000004922996,0.000692191,0.0003060303,0.0001757058,0.0007004122,0.000006565899,0.0003518449,0.0003064518,0.9962234,0.0005848518],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002311452,0.9969308,0.001715346,0.00003397586,0.0002561095,0.00062459,0.00003469272,0.00003984481,0.000133519],"genre_scores_gemma":[0.004493141,0.9938065,0.00009189415,0.0000378039,0.0005602947,0.0001508065,0.0007520013,0.00009133499,0.00001616837],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9962068,"threshold_uncertainty_score":0.9997516,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3213709497","doi":"10.1038/s41392-021-00779-x","title":"Roles and mechanisms of exosomal non-coding RNAs in human health and diseases","year":2021,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":397,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Aging","funders":"Fundamental Research Funds for the Central Universities; Central South University; National Natural Science Foundation of China","keywords":"Microvesicles; microRNA; Exosome; Biology; Computational biology; Circular RNA; Biomarker; Diagnostic biomarker; Long non-coding RNA; Non-coding RNA; Bioinformatics; RNA; Gene; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.02292044452079976,"gpt":0.3076912217555403,"spread":0.2847707772347405,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001373864,0.0002625938,0.0006583648,0.0001029759,0.00008330281,0.0000239354,0.00006762151,0.0001818236,0.00003084179],"category_scores_gemma":[0.000005415164,0.0002419544,0.0001396378,0.00009825617,0.0001180429,0.000006552671,0.00002227553,0.0001352527,8.898687e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009079494,"about_ca_system_score_gemma":0.0001351935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009119687,"about_ca_topic_score_gemma":0.000007479462,"domain_scores_codex":[0.9986996,0.0002082324,0.0003684303,0.0004481166,0.00009882759,0.0001767845],"domain_scores_gemma":[0.9994947,0.00001244835,0.0001508566,0.0001506018,0.00002560555,0.0001657853],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009863234,0.0002635822,0.00006011758,0.005534383,0.0003104166,0.00001695205,0.0002148957,0.000001901625,0.1399001,0.001184112,0.00002537022,0.8523895],"study_design_scores_gemma":[0.01331422,0.006071926,0.0008319741,0.02433811,0.001203037,0.0005828531,0.002570772,0.00008085599,0.268141,0.009651211,0.6685654,0.00464866],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007579722,0.9895207,0.00236448,0.00002435404,0.00004950598,0.0003677109,0.00007769449,0.000006916715,0.000008877536],"genre_scores_gemma":[0.05945655,0.9397557,0.0001851194,0.00004389862,0.00008673078,0.00002791246,0.0003854337,0.0000340186,0.00002460647],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8477408,"threshold_uncertainty_score":0.9866616,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4389030365","doi":"10.1038/s41392-023-01655-6","title":"Signaling pathways and targeted therapies for psoriasis","year":2023,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":360,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SKiN Health","funders":"National Natural Science Foundation of China","keywords":"Psoriasis; Disease; Mechanism (biology); Medicine; Epigenetics; Pathogenesis; Bioinformatics; Intensive care medicine; Immunology; Biology; Pathology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.08059675380004618,"gpt":0.2949508710315138,"spread":0.2143541172314676,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004376452,0.0007512346,0.001606299,0.0003974921,0.0005447296,0.00006113546,0.0001668327,0.0008607189,0.0005852537],"category_scores_gemma":[0.00001248631,0.0005718656,0.000611955,0.0003608765,0.0002056277,0.0001146538,0.00001424713,0.0003296603,0.0000591766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003288289,"about_ca_system_score_gemma":0.0001098161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002033281,"about_ca_topic_score_gemma":0.000004688184,"domain_scores_codex":[0.9974711,0.0004722618,0.0006534433,0.0008084232,0.00006550502,0.0005292721],"domain_scores_gemma":[0.9988667,0.0004869914,0.0002731386,0.0002276214,0.00008097284,0.00006457816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002891113,0.00009509156,0.000003339513,0.001462067,0.003335635,0.000003865139,0.0009189153,4.808255e-7,0.008507605,0.000308572,0.000181611,0.9848937],"study_design_scores_gemma":[0.003168486,0.0005914898,0.00001735193,0.001029265,0.001291043,0.00006718508,0.0003257493,0.000001218066,0.005220546,0.001101248,0.986412,0.0007743478],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001617176,0.9938353,0.0002684576,0.0000516827,0.001424317,0.001637997,0.0008185497,0.0003264332,0.00002009333],"genre_scores_gemma":[0.001147259,0.9950963,0.0002008604,0.00003945047,0.0003287697,0.0006802619,0.001646847,0.0001412686,0.0007189457],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9862304,"threshold_uncertainty_score":0.9996733,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2760019720","doi":"10.1038/sigtrans.2017.40","title":"Targeting cellular pathways in glioblastoma multiforme","year":2017,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":350,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"John and Lucille Van Geest Foundation; Trent University; Headcase Cancer Trust; Nottingham Trent University","keywords":"Glioblastoma; Medicine; Computational biology; Pathology; Cancer research; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.07417124488464162,"gpt":0.3214597366623669,"spread":0.2472884917777253,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002662496,0.0005531759,0.001647502,0.0004425839,0.0002058032,0.00006550941,0.0001093748,0.0003981845,0.0005461983],"category_scores_gemma":[0.00001206142,0.000401326,0.000515527,0.0002036012,0.0000972713,0.000116353,0.00001002507,0.000476947,0.00004026879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009805083,"about_ca_system_score_gemma":0.0001437269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005142303,"about_ca_topic_score_gemma":0.000007906471,"domain_scores_codex":[0.9980048,0.0001268706,0.0006330768,0.0005922794,0.0002517028,0.0003912664],"domain_scores_gemma":[0.9990999,0.000057434,0.0002746346,0.0003209042,0.00005508168,0.0001920607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001376688,0.0004921198,0.00005243465,0.002139248,0.0003548343,0.0002933243,0.000222048,0.000001633422,0.001137603,0.00004697858,0.00004490721,0.9950772],"study_design_scores_gemma":[0.003593811,0.0006670594,0.00004562673,0.004947271,0.0003726161,0.0001435496,0.00005501215,0.00003959401,0.001875573,0.00007439522,0.9877309,0.0004546074],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002371962,0.9954958,0.00003137065,0.00007264435,0.0003042599,0.001471051,0.00005110462,0.00007567905,0.0001261535],"genre_scores_gemma":[0.01701812,0.9818946,0.0001483817,0.00003125279,0.0003249254,0.0002429008,0.0002059137,0.0000813943,0.00005249705],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9946226,"threshold_uncertainty_score":0.9998438,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4386446579","doi":"10.1038/s41392-023-01589-z","title":"Recent advances in targeting the “undruggable” proteins: from drug discovery to clinical trials","year":2023,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Protein Degradation and Inhibitors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":344,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Chengdu University; Jiangxi University of Traditional Chinese Medicine; Chengdu University of Traditional Chinese Medicine; National Natural Science Foundation of China","keywords":"Drug discovery; Computational biology; Drug development; Biology; Drug; Bioinformatics; Pharmacology","retraction":null,"screen_n_in":null,"score":{"opus":0.1058780823456495,"gpt":0.4042721095420451,"spread":0.2983940271963956,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003462764,0.0004035546,0.001169192,0.00012845,0.0001422626,0.0001069969,0.0002697709,0.0003338964,0.0001300716],"category_scores_gemma":[0.0003795857,0.0002532422,0.0004913758,0.0004277682,0.000099648,0.00002735953,0.00003575553,0.0004697359,0.00002015305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002274095,"about_ca_system_score_gemma":0.0001967732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002792546,"about_ca_topic_score_gemma":0.00005115883,"domain_scores_codex":[0.9949706,0.002329527,0.001430953,0.0007601105,0.0002219983,0.0002868465],"domain_scores_gemma":[0.9988737,0.0002463426,0.0004089482,0.0002988608,0.00005662762,0.0001155595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002006468,0.0000707702,0.000007046134,0.0002132594,0.0001695532,0.000001598282,0.00006577692,0.000009281376,0.001106953,0.00001792252,0.00108181,0.9970554],"study_design_scores_gemma":[0.000630416,0.0001506779,0.000004887767,0.0008850107,0.00005232401,0.000001571676,0.0001198146,0.00000270283,0.002741704,0.0001979872,0.9948865,0.0003263964],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006150981,0.9942813,0.0007180621,0.0005121008,0.001081301,0.002552894,0.0001726607,0.00003610934,0.00003049336],"genre_scores_gemma":[0.0001142518,0.9957568,0.0001794005,0.0002418838,0.00178765,0.00057369,0.0008670054,0.00006570142,0.0004136088],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.996729,"threshold_uncertainty_score":0.999992,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2890296921","doi":"10.1038/s41392-018-0022-9","title":"The intracellular signalosome of PD-L1 in cancer cells","year":2018,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":290,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Infection and Immunity","funders":"Fundación Española para la Ciencia y la Tecnología; Universidad Pública de Navarra; Instituto de Salud Carlos III; Ministerio de Economía y Competitividad","keywords":"Intracellular; Cancer; Biology; Chemistry; Cell biology; Computational biology; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.04542014459269217,"gpt":0.3225375459027454,"spread":0.2771174013100532,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004912562,0.0003772,0.00109621,0.0002256344,0.0001146392,0.00002364158,0.000143321,0.000319789,0.001211798],"category_scores_gemma":[0.000002727587,0.0002268415,0.0004796241,0.0005578509,0.0004239629,0.00005404322,0.000005687662,0.0004185377,0.000005738385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009130037,"about_ca_system_score_gemma":0.0003184809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001506402,"about_ca_topic_score_gemma":0.0000278457,"domain_scores_codex":[0.9980649,0.0002193036,0.0007692205,0.0003822014,0.0002670579,0.0002972539],"domain_scores_gemma":[0.9991742,0.0001115896,0.0002848911,0.0002600385,0.00008786702,0.00008141842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001537191,0.0001536701,0.000005035927,0.0024288,0.0007756828,0.000006873665,0.0003003623,5.181984e-7,0.01643017,0.00002203695,0.0002659798,0.9780737],"study_design_scores_gemma":[0.001695847,0.0005530561,0.00002047946,0.003693008,0.0002446477,0.00002943292,0.0000594306,0.000005735393,0.013486,0.00006927241,0.9798928,0.0002503262],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001160994,0.9967057,0.0000366571,0.0001865867,0.000606217,0.001142976,0.00005172061,0.00002552103,0.00008361922],"genre_scores_gemma":[0.0012796,0.9975415,0.0000331356,0.00007866143,0.0004227154,0.0001251353,0.00003876756,0.00005482028,0.0004256938],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9796268,"threshold_uncertainty_score":0.9997012,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4200414711","doi":"10.1038/s41392-021-00852-5","title":"SARS-CoV-2 Omicron strain exhibits potent capabilities for immune evasion and viral entrance","year":2021,"lang":"en","type":"letter","venue":"Signal Transduction and Targeted Therapy","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":288,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Infection and Immunity","funders":"Fundamental Research Funds for the Central Universities; National Key Research and Development Program of China; Sun Yat-sen University; National Natural Science Foundation of China","keywords":"Evasion (ethics); Virology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Strain (injury); Coronavirus disease 2019 (COVID-19); Immune system; 2019-20 coronavirus outbreak; Immune escape; Biology; Immunology; Medicine; Pathology; Infectious disease (medical specialty)","retraction":null,"screen_n_in":null,"score":{"opus":0.04435947455376119,"gpt":0.3068261158400545,"spread":0.2624666412862933,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003775577,0.0005246616,0.0007989287,0.0002680592,0.000227163,0.0001109962,0.000114925,0.0007319301,0.00007053956],"category_scores_gemma":[0.00001736068,0.000457976,0.0003689155,0.0001748299,0.0003425582,0.0001456523,0.00001252506,0.001240185,0.000003057203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001101758,"about_ca_system_score_gemma":0.0002657058,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001348571,"about_ca_topic_score_gemma":0.00001063262,"domain_scores_codex":[0.9972755,0.0002006304,0.0005220953,0.0008677578,0.0005057566,0.000628253],"domain_scores_gemma":[0.999162,0.000131251,0.0001067989,0.0003143465,0.0002444135,0.00004119023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001499428,0.0001272568,0.00005128627,0.0008653171,0.0003288075,0.00008225472,0.0009571569,2.586409e-7,0.9665509,0.0000229361,0.006944996,0.02256933],"study_design_scores_gemma":[0.003570109,0.0007038736,0.00014734,0.0001939799,0.00006693212,0.0001216348,0.0001656526,0.00004669292,0.5811682,0.0004641943,0.4130428,0.0003086726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.8316427,0.04092908,0.001707887,0.1215964,0.000764898,0.002641819,0.0004325227,0.0001566207,0.0001280671],"genre_scores_gemma":[0.242743,0.003314312,0.0005907733,0.7475029,0.004081771,0.0003974103,0.0008036834,0.000226923,0.0003392849],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.6259064,"threshold_uncertainty_score":0.9997872,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3206218751","doi":"10.1038/s41392-021-00765-3","title":"Mesenchymal stem cell-derived small extracellular vesicles mitigate oxidative stress-induced senescence in endothelial cells via regulation of miR-146a/Src","year":2021,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":269,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University Health Centre","funders":"National Key Research and Development Program of China; Higher Education Discipline Innovation Project; National Natural Science Foundation of China","keywords":"Senescence; Mesenchymal stem cell; Angiogenesis; Cell biology; Stem cell; Biology; Oxidative stress; Endothelial stem cell; Cancer research; In vitro; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.01431841512841141,"gpt":0.2215373473830019,"spread":0.2072189322545905,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001931089,0.000264977,0.0002570662,0.00008093973,0.00008117886,0.00002506623,0.0001289613,0.0002151537,0.0001514078],"category_scores_gemma":[0.000004733341,0.0002800298,0.0001402969,0.0002090618,0.0001435804,0.00002075042,0.00001983415,0.0001594503,0.000002450197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001646727,"about_ca_system_score_gemma":0.0001151957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002598618,"about_ca_topic_score_gemma":0.00002406341,"domain_scores_codex":[0.9981547,0.0003678178,0.000429657,0.0005662133,0.0002016269,0.0002799576],"domain_scores_gemma":[0.9992371,0.00002530782,0.0001677591,0.0002821047,0.0001608686,0.0001269259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005231981,0.0003566229,0.0004524598,0.00006136564,0.00006708401,0.000022495,0.0006104364,0.0003121819,0.9913979,0.00002904193,0.000004341722,0.006162909],"study_design_scores_gemma":[0.001964632,0.0002377174,0.00235659,0.00003884879,0.00002236622,0.00001147053,0.0006184971,0.0003627443,0.9937114,0.0002008491,0.0001858119,0.0002891495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986051,0.005576699,0.00764088,0.00007539281,0.0001660174,0.0003307854,0.00009348208,0.00001899222,0.00004671633],"genre_scores_gemma":[0.9970963,0.001074877,0.001214153,0.00003564284,0.0001272227,0.0000194084,0.0001917206,0.00003772313,0.0002029599],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01104526,"threshold_uncertainty_score":0.9999652,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4390599722","doi":"10.1038/s41392-023-01687-y","title":"The role of inflammasomes in human diseases and their potential as therapeutic targets","year":2024,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":218,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"National Natural Science Foundation of China","keywords":"Inflammasome; Innate immune system; AIM2; Pyroptosis; Effector; Disease; Inflammation; Biology; Caspase 1; Medicine; Immunology; Cancer research; Immune system; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.003864738860871687,"gpt":0.218801009814542,"spread":0.2149362709536703,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001023083,0.0001332052,0.0001058991,0.00005699683,0.000132047,0.00004295596,0.00006678764,0.00007368931,0.00005741102],"category_scores_gemma":[0.000001853059,0.0000876156,0.0000749302,0.00008213234,0.0001735363,0.00001156127,0.000009520862,0.00008599241,6.436812e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002836312,"about_ca_system_score_gemma":0.0000298471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002089948,"about_ca_topic_score_gemma":0.00001058763,"domain_scores_codex":[0.9993496,0.0000696067,0.0001665377,0.0002002525,0.00006243354,0.0001515593],"domain_scores_gemma":[0.9998114,0.00001182209,0.00002445159,0.00009725443,0.00002496054,0.0000300722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002050089,0.00002983882,0.000656932,0.0000114489,0.000120664,9.07668e-7,0.0006011669,0.00001633725,0.922105,0.0009396927,0.000007814292,0.07530526],"study_design_scores_gemma":[0.0008405349,0.0004746253,0.007585194,0.00001910075,0.00001517412,0.00001227783,0.002145366,0.0001726891,0.9186866,0.01495724,0.05489512,0.0001961031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8421691,0.157161,0.00009438652,0.000183116,0.00009427297,0.000148637,0.000009274605,0.00001254961,0.000127684],"genre_scores_gemma":[0.9847467,0.01494541,0.000003764841,0.00004378658,0.00008590877,0.00001908772,0.00004465111,0.00001622823,0.00009444858],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1425776,"threshold_uncertainty_score":0.357286,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2950457484","doi":"10.1038/s41392-018-0034-5","title":"Predicting responses to platin chemotherapy agents with biochemically-inspired machine learning","year":2019,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":204,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Compute Canada","keywords":"ERCC1; Carboplatin; Cisplatin; Bladder cancer; Oxaliplatin; Gene signature; Oncology; Cancer research; Medicine; Prostate cancer; Colorectal cancer; Internal medicine; Cancer; Biology; Chemotherapy; Gene; Gene expression; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.009670040946013501,"gpt":0.2343365067016757,"spread":0.2246664657556622,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001571635,0.0002016318,0.0001872639,0.00007263202,0.0001038792,0.00002860312,0.00008426275,0.0001155958,0.0004702159],"category_scores_gemma":[0.000008120263,0.000169221,0.00006592937,0.0001411685,0.00004657399,0.000008846617,0.000008705299,0.0001428062,0.000006004283],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008696289,"about_ca_system_score_gemma":0.00004470577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005452366,"about_ca_topic_score_gemma":0.00001017865,"domain_scores_codex":[0.9989415,0.00007771135,0.0001729169,0.0004165712,0.0001557708,0.0002354989],"domain_scores_gemma":[0.9995927,0.00001105199,0.0000584239,0.0001539521,0.00005946857,0.0001244616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003500619,0.00004883685,0.01486903,0.000010865,0.0001061806,8.965525e-8,0.0005531351,0.0001328823,0.9715559,0.000004870607,0.0003445878,0.008872984],"study_design_scores_gemma":[0.003900686,0.001321805,0.01077935,0.0000271535,0.00001401343,0.00002094632,0.0002273115,0.0002756759,0.6645053,0.00001300458,0.3185731,0.0003417037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953303,0.001909761,0.001047397,0.0002776488,0.000757774,0.000389806,0.00002161586,0.00004944788,0.0002162897],"genre_scores_gemma":[0.9935867,0.0017727,0.0006414853,0.0007002082,0.001859189,0.000026761,0.00009920105,0.00004345279,0.001270333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3182285,"threshold_uncertainty_score":0.6900634,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4293537593","doi":"10.1038/s41392-022-01152-2","title":"The RING finger protein family in health and disease","year":2022,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":183,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Calgary","funders":"Qinghai Provincial Department of Science and Technology; Natural Science Foundation of Fujian Province; National Natural Science Foundation of China","keywords":"Ring finger; Disease; Computational biology; Ring (chemistry); Biology; Genetics; Medicine; Pathology; Chemistry; Gene","retraction":null,"screen_n_in":null,"score":{"opus":0.04467298119070677,"gpt":0.2947246820252592,"spread":0.2500517008345524,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000431998,0.0002418808,0.0003423343,0.00006217624,0.0003170106,0.00004276129,0.0001064543,0.000100217,0.00007059591],"category_scores_gemma":[0.00001506614,0.0001738035,0.000127957,0.0001213382,0.00008186069,0.000003628046,0.00002320382,0.0002963167,7.441074e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001750228,"about_ca_system_score_gemma":0.0003072633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001844865,"about_ca_topic_score_gemma":0.00000411842,"domain_scores_codex":[0.9985117,0.000435452,0.0003091425,0.0003919498,0.0001143618,0.0002373501],"domain_scores_gemma":[0.9995045,0.00002159554,0.0001159157,0.0001650206,0.000009811961,0.0001831565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001316313,0.00003437484,0.000002997426,0.001164306,0.00005718868,0.000002454635,0.00009123319,0.000001020677,0.001273304,0.0001389588,0.00004457018,0.997058],"study_design_scores_gemma":[0.0003440686,0.0002509592,0.000006172395,0.0003900732,0.000009146313,0.00000805677,0.00006110726,0.00000351214,0.0001690642,0.000206222,0.9983542,0.0001974506],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001231965,0.9972432,0.00005151727,0.0001861745,0.00009627426,0.001075045,0.00004594871,0.00001279116,0.00005713862],"genre_scores_gemma":[0.0008703217,0.9978886,0.0000371441,0.0001864557,0.0001507747,0.0004301606,0.0001818367,0.00003560919,0.0002190842],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9983096,"threshold_uncertainty_score":0.7087502,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4212787271","doi":"10.1038/s41392-021-00870-3","title":"Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia","year":2022,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":181,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Cancer Institute; U.S. Department of Health and Human Services; National Institutes of Health; Université de Paris; University of Texas MD Anderson Cancer Center; AbbVie","keywords":"Venetoclax; Myeloid leukemia; Cancer research; Leukemia; MAPK/ERK pathway; Medicine; Myeloid; Apoptosis; Biology; Immunology; Signal transduction; Cell biology; Genetics; Chronic lymphocytic leukemia","retraction":null,"screen_n_in":null,"score":{"opus":0.01875768575998418,"gpt":0.2636010988375339,"spread":0.2448434130775497,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005567478,0.0002366181,0.0004534387,0.0005422921,0.000175429,0.00001501017,0.0001389213,0.0001277143,0.001095775],"category_scores_gemma":[0.00003341131,0.0002299121,0.0001002919,0.001131345,0.000128978,0.000159664,0.0000244007,0.0004342287,0.000005708739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001174546,"about_ca_system_score_gemma":0.0009593483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001558329,"about_ca_topic_score_gemma":0.00002636874,"domain_scores_codex":[0.9976924,0.000292651,0.0004964367,0.0004723167,0.0006601911,0.0003859894],"domain_scores_gemma":[0.9991568,0.0001167541,0.0001161124,0.0002402552,0.0001590275,0.0002110001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008841748,0.0001072384,0.0004998117,0.00005333159,0.0001712338,0.00002679991,0.002585521,0.0003237266,0.9822518,0.0001386358,0.0006385708,0.004361568],"study_design_scores_gemma":[0.01037862,0.001405254,0.008857058,0.0001000396,0.00002745325,0.00002672698,0.001549126,0.0005426992,0.9432774,0.0002453406,0.03326109,0.0003291797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944087,0.0006160213,0.0005322457,0.002590525,0.0001972334,0.001247935,0.0001091248,0.00008136872,0.0002168321],"genre_scores_gemma":[0.9968868,0.0006694731,0.000362217,0.000717368,0.0001221377,0.0002287013,0.000271931,0.0000498487,0.0006915195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0389744,"threshold_uncertainty_score":0.9998174,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3112301923","doi":"10.1038/s41392-020-00360-y","title":"Fulminant myocarditis: a comprehensive review from etiology to treatments and outcomes","year":2020,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":164,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"Tongji University; National Natural Science Foundation of China","keywords":"Fulminant; Myocarditis; Medicine; Etiology; Pathophysiology; Intensive care medicine; Cytokine storm; Clinical trial; Acute myocarditis; Mechanism (biology); Cardiology; Bioinformatics; Internal medicine; Pathology; Disease; Coronavirus disease 2019 (COVID-19)","retraction":null,"screen_n_in":null,"score":{"opus":0.08089916316962174,"gpt":0.3864668701877197,"spread":0.305567707018098,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007497439,0.0004045741,0.0022136,0.0001873822,0.0001361401,0.00001866661,0.00005838247,0.0002661521,0.0007461162],"category_scores_gemma":[0.00001325556,0.0002749696,0.0003819189,0.0003115771,0.0001518953,0.00004941355,0.00001793757,0.0004911728,0.00007310363],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004683688,"about_ca_system_score_gemma":0.0001066893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000807477,"about_ca_topic_score_gemma":0.000001146029,"domain_scores_codex":[0.9982689,0.0003538863,0.0004433485,0.0005553034,0.0001330338,0.0002455537],"domain_scores_gemma":[0.9993089,0.0001009523,0.00009037573,0.0002006554,0.00008645598,0.0002125984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001009591,0.00008508353,0.00004277363,0.002688771,0.002111395,0.00003952289,0.00007732288,1.930138e-8,0.0001842083,0.00001023075,0.0004012234,0.9942585],"study_design_scores_gemma":[0.001158166,0.001477825,0.001040626,0.005779078,0.001028991,0.0002255671,0.00003016021,5.188552e-7,0.00002495711,0.00003483217,0.9889722,0.0002271098],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00040919,0.995038,0.00007158978,0.001992101,0.000210717,0.001987321,0.000178686,0.00006010572,0.00005228375],"genre_scores_gemma":[0.00009280177,0.9974356,0.0001488769,0.001312936,0.000136082,0.0003063409,0.0004013197,0.00004104834,0.0001250426],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9940314,"threshold_uncertainty_score":0.9999703,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4212932622","doi":"10.1038/s41392-021-00865-0","title":"Nuclear genome-derived circular RNA circPUM1 localizes in mitochondria and regulates oxidative phosphorylation in esophageal squamous cell carcinoma","year":2022,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Circular RNAs in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":130,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Basic and Applied Basic Research Foundation of Guangdong Province; Shenzhen Bay Laboratory; National Natural Science Foundation of China; Baidu; Sunnybrook Research Institute","keywords":"Mitochondrion; Cell biology; Oxidative phosphorylation; Biology; Intracellular; Cell; Cell culture; Biochemistry; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.007417147852447031,"gpt":0.205951035620951,"spread":0.198533887768504,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000143484,0.0001868535,0.000176775,0.0001375712,0.0001554304,0.00002580168,0.00009750363,0.00009394626,0.0003972467],"category_scores_gemma":[0.000006201009,0.0002149492,0.00006750881,0.0002044801,0.0001146361,0.0000143113,0.00002857402,0.0001721206,9.517854e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004336048,"about_ca_system_score_gemma":0.00004221777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008192586,"about_ca_topic_score_gemma":0.00001263494,"domain_scores_codex":[0.9986898,0.0002340856,0.0002316086,0.0004719133,0.0001557692,0.0002168639],"domain_scores_gemma":[0.9996604,0.00001175748,0.00006405574,0.0001586565,0.000028864,0.00007627443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005567078,0.0001798136,0.004327309,0.00001975891,0.0000200113,0.00002002362,0.000915185,0.001147136,0.9919108,0.00002192464,0.00001260351,0.0008687928],"study_design_scores_gemma":[0.004770007,0.0006065663,0.1249919,0.000004603339,0.00001773186,0.00003330417,0.001480764,0.0006428927,0.8646083,0.0005509674,0.00188197,0.0004109092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837313,0.01542117,0.0001886153,0.00007173896,0.00009509858,0.0003917549,0.0000390848,0.00001645517,0.00004476622],"genre_scores_gemma":[0.998792,0.0005830992,0.00009785,0.0001391642,0.00006135499,0.0000518341,0.0002116173,0.00003706179,0.00002603185],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1273024,"threshold_uncertainty_score":0.8765374,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3014732242","doi":"10.1038/s41392-020-0145-7","title":"NLRP3 inflammasome as a novel therapeutic target for Alzheimer’s disease","year":2020,"lang":"en","type":"letter","venue":"Signal Transduction and Targeted Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia Hospital; University of British Columbia","funders":"National Natural Science Foundation of China; Michael Smith Health Research BC","keywords":"Inflammasome; Disease; Alzheimer's disease; Medicine; Computational biology; Biology; Immunology; Pathology; Inflammation","retraction":null,"screen_n_in":null,"score":{"opus":0.06325197781661109,"gpt":0.3137072060230861,"spread":0.250455228206475,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009918111,0.0007246971,0.0007972004,0.0002791073,0.0003033888,0.00009411258,0.0001612293,0.0004440417,0.001706946],"category_scores_gemma":[0.00001305125,0.0005891455,0.0006439642,0.0002799239,0.0002710033,0.0001721604,0.00001268059,0.001117362,0.00007988697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005849231,"about_ca_system_score_gemma":0.0006799751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002349399,"about_ca_topic_score_gemma":3.422631e-7,"domain_scores_codex":[0.9969364,0.0001184833,0.000449985,0.0009726391,0.0007626037,0.0007598637],"domain_scores_gemma":[0.9983031,0.0001234241,0.0001443844,0.0003679268,0.0002335694,0.0008275566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.06839229,0.004892875,0.002211412,0.002868199,0.2073592,0.006075256,0.001848122,0.00002835426,0.02102635,0.0009068292,0.6176696,0.06672154],"study_design_scores_gemma":[0.01420131,0.003430367,0.0008679953,0.0001692597,0.003683428,0.00009881943,0.00005450308,0.000317205,0.005313846,0.007024872,0.9638512,0.000987209],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002606354,0.1263918,0.001853768,0.8596147,0.0005763667,0.006424691,0.001755719,0.0004746813,0.0003018855],"genre_scores_gemma":[0.2679781,0.0102097,0.001522002,0.6944497,0.01027651,0.002097784,0.01209483,0.0005802381,0.0007911782],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.3461816,"threshold_uncertainty_score":0.999656,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2992050936","doi":"10.1038/s41392-019-0091-4","title":"MKP-1 reduces Aβ generation and alleviates cognitive impairments in Alzheimer’s disease models","year":2019,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":117,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"National Key Research and Development Program of China; Chongqing Municipal Education Commission; National Natural Science Foundation of China","keywords":"Downregulation and upregulation; MAPK/ERK pathway; Neuroprotection; Signal transduction; Protein tyrosine phosphatase; Alzheimer's disease; Kinase; Amyloid precursor protein; Phosphatase; Biology; Protein kinase A; Cell biology; Long-term potentiation; Phosphorylation; Neuroscience; Internal medicine; Medicine; Biochemistry; Gene; Receptor; Disease","retraction":null,"screen_n_in":null,"score":{"opus":0.05220915398323118,"gpt":0.3087245410883813,"spread":0.2565153871051501,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001015811,0.0001827014,0.0002139244,0.0001476265,0.00007882054,0.000030683,0.00002309906,0.00005882632,0.0003845072],"category_scores_gemma":[0.000002316273,0.0001472045,0.0000609981,0.0001290843,0.00007923254,0.0003731326,0.000005333309,0.0001186941,0.00001385851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000184943,"about_ca_system_score_gemma":0.0000783275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006864801,"about_ca_topic_score_gemma":0.000002764506,"domain_scores_codex":[0.9988862,0.00009571169,0.0001753811,0.000361951,0.0002430296,0.0002377551],"domain_scores_gemma":[0.9994636,0.000023356,0.00003412535,0.00007870884,0.00007356649,0.0003267127],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03938391,0.009151139,0.4750659,0.0002898735,0.02865678,0.0009068752,0.01130218,0.0002865186,0.1016312,0.0006594122,0.0002609157,0.3324053],"study_design_scores_gemma":[0.06224864,0.006596789,0.7888927,0.0007695803,0.002001442,0.0001814594,0.002740223,0.04883802,0.0779619,0.007941268,0.0002615749,0.001566357],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9454777,0.05251449,0.00003203222,0.0005365791,0.00005899091,0.001210979,0.00004488439,0.00003491398,0.00008947385],"genre_scores_gemma":[0.9894266,0.009761577,0.00005647817,0.0002160344,0.0001082587,0.000118398,0.0002695811,0.0000217684,0.00002133361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.330839,"threshold_uncertainty_score":0.6002826,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4410198207","doi":"10.1038/s41392-025-02192-0","title":"The molecular mechanism and therapeutic landscape of copper and cuproptosis in cancer","year":2025,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Trace Elements in Health","field":"Nursing","cited_by":115,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SKiN Health","funders":"Xiangya Hospital, Central South University; National Natural Science Foundation of China","keywords":"Cancer; Cancer cell; Cancer therapy; Mechanism (biology); Biology; Cancer treatment; Metastasis; Computational biology; Bioinformatics; Cancer research; Medicine; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.03211555070330996,"gpt":0.3427461272712188,"spread":0.3106305765679089,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003642467,0.000305193,0.0007279861,0.0002073817,0.0001642854,0.00003792392,0.00009669806,0.0002145102,0.00006279998],"category_scores_gemma":[0.000004202945,0.0002031059,0.00009536482,0.0003148901,0.0001210682,0.00004330029,0.000008622033,0.0003700064,2.032276e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003495022,"about_ca_system_score_gemma":0.00008565881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009454601,"about_ca_topic_score_gemma":0.00003919837,"domain_scores_codex":[0.9983366,0.0003940164,0.0004676117,0.0003755309,0.0001709811,0.0002552985],"domain_scores_gemma":[0.999386,0.0002040075,0.0001609678,0.000155605,0.00003791047,0.00005552857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001346636,0.0000427317,0.00004458022,0.003359034,0.0001693971,6.928517e-7,0.0003922829,0.000001231733,0.0004817579,0.001089806,0.00001058375,0.9942732],"study_design_scores_gemma":[0.004417156,0.001180058,0.0003129486,0.01228484,0.001038965,0.00003778416,0.000631092,0.00009280609,0.005254569,0.01047122,0.963218,0.001060591],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002853989,0.9948322,0.00005577895,0.0005799151,0.0004623213,0.001122778,0.00004134539,0.00002428966,0.00002740564],"genre_scores_gemma":[0.01967744,0.9798353,0.00006922093,0.0001438616,0.0000461737,0.0001541065,0.00001012389,0.00003457304,0.00002921616],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9932126,"threshold_uncertainty_score":0.8282419,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3183386301","doi":"10.1038/s41392-021-00704-2","title":"N501Y mutation imparts cross-species transmission of SARS-CoV-2 to mice by enhancing receptor binding","year":2021,"lang":"en","type":"letter","venue":"Signal Transduction and Targeted Therapy","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Biotechnology Research Institute","funders":"Beijing Municipal Administration of Hospitals","keywords":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Virology; Mutation; Transmission (telecommunications); Sars virus; Receptor; Betacoronavirus; Biology; Molecular biology; Medicine; Genetics; Pathology; Gene; Disease","retraction":null,"screen_n_in":null,"score":{"opus":0.05250129707126622,"gpt":0.3420590178349025,"spread":0.2895577207636363,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003947207,0.0004754241,0.000781531,0.0005324556,0.000206828,0.0001149666,0.0001485763,0.0007271497,0.000519603],"category_scores_gemma":[0.00002001064,0.0004265664,0.0003336048,0.0006988838,0.0001783163,0.0001914845,0.000009504956,0.001207437,0.00003232968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001319798,"about_ca_system_score_gemma":0.0002712357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001000932,"about_ca_topic_score_gemma":0.000006092515,"domain_scores_codex":[0.9968852,0.000221975,0.0006972165,0.0007941202,0.0008561581,0.000545327],"domain_scores_gemma":[0.9989985,0.0001345041,0.0001677769,0.0002413238,0.0003931374,0.00006477709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001017048,0.000113352,0.0001025298,0.000480056,0.0002526809,0.00006749141,0.001508732,7.279623e-7,0.9319164,0.000001421114,0.05830688,0.006232733],"study_design_scores_gemma":[0.001219556,0.0003903527,0.00003343972,0.0002462756,0.00003250064,0.00003695998,0.0001109231,0.00001036931,0.541604,0.00001224342,0.4560844,0.0002189836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.9334791,0.006265024,0.006757122,0.05087589,0.0006644907,0.001268288,0.0002087318,0.0001406838,0.0003406074],"genre_scores_gemma":[0.2083439,0.001430477,0.001348682,0.7818149,0.003658391,0.0002102345,0.001539176,0.0003137777,0.001340445],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.730939,"threshold_uncertainty_score":0.9998186,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4285009772","doi":"10.1038/s41392-022-01082-z","title":"Nanoparticles in the diagnosis and treatment of vascular aging and related diseases","year":2022,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Advanced Nanomaterials in Catalysis","field":"Materials Science","cited_by":103,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Aging","funders":"National Natural Science Foundation of China","keywords":"Medicine; Oxidative stress; Inflammation; Senescence; Epigenetics; Bioinformatics; Pathology; Biology; Immunology; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.04824542583588769,"gpt":0.3046032158332589,"spread":0.2563577899973712,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027146,0.0002449166,0.0007423165,0.0001362475,0.0001535859,0.00004341739,0.000089189,0.00006605371,0.000821603],"category_scores_gemma":[0.000007312046,0.0001533262,0.0001286586,0.0002799069,0.0001876058,0.0001150859,0.0000113691,0.00005780395,7.014859e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003315756,"about_ca_system_score_gemma":0.00002660561,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003443671,"about_ca_topic_score_gemma":0.000002508738,"domain_scores_codex":[0.9983656,0.0005334599,0.0004118909,0.0003708393,0.0001635316,0.0001546337],"domain_scores_gemma":[0.9993494,0.0002622948,0.0001619858,0.0001747448,0.000009103349,0.00004243669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003824692,0.0002292658,0.00007524336,0.0007230647,0.0001343426,0.00001259692,0.001706651,0.00001398882,0.0116578,0.00005785202,0.000001252043,0.9853497],"study_design_scores_gemma":[0.002887882,0.001137036,0.0004666894,0.001202791,0.001722501,0.0001336563,0.0009525646,0.00001292007,0.03856784,0.00180824,0.950256,0.0008518246],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1716706,0.8275484,0.000003540115,0.00002687437,0.0001117438,0.0005152504,0.0001005051,0.00002080177,0.000002253679],"genre_scores_gemma":[0.02917427,0.970251,0.00006027587,0.000008305647,0.00003255438,0.0003951297,0.00005341549,0.00002111818,0.000003963172],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9844978,"threshold_uncertainty_score":0.8995976,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4394060597","doi":"10.1038/s41392-024-01801-8","title":"The gasdermin family: emerging therapeutic targets in diseases","year":2024,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Infection and Immunity","funders":"National Natural Science Foundation of China","keywords":"Pyroptosis; Effector; Disease; Inflammasome; Medicine; Computational biology; Biology; Bioinformatics; Immunology; Inflammation; Pathology","retraction":null,"screen_n_in":null,"score":{"opus":0.02081046558491485,"gpt":0.2979293698823327,"spread":0.2771189042974178,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001965466,0.0004125503,0.0004874131,0.0001286242,0.0001926709,0.00008282423,0.0001924697,0.0002465018,0.00004944867],"category_scores_gemma":[0.000004364045,0.0002619018,0.0004026234,0.0002484911,0.0001347929,0.000007030508,0.00001922808,0.0003163472,0.00001303545],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001472412,"about_ca_system_score_gemma":0.0001439794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007143534,"about_ca_topic_score_gemma":0.000009441165,"domain_scores_codex":[0.998414,0.0002301817,0.0004154291,0.0004757002,0.0001274792,0.0003371939],"domain_scores_gemma":[0.9995698,0.00002174895,0.00008366309,0.0002440557,0.00002834291,0.00005242622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006887299,0.00004002382,0.000002816386,0.0005667816,0.0003685113,0.000004819106,0.0001341777,0.000002383823,0.002105631,0.00007948956,0.0002960067,0.9963305],"study_design_scores_gemma":[0.000336339,0.0001265403,0.00001150055,0.0003849503,0.0001630536,0.00001265024,0.0002483391,0.000007309115,0.0003465191,0.0002853423,0.9977443,0.0003332065],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000227849,0.998362,0.00009384729,0.00007873317,0.0005246628,0.0005397121,0.00003316751,0.00002612768,0.0001139027],"genre_scores_gemma":[0.002002758,0.9965878,0.000006938063,0.0001024436,0.0002596883,0.0001667452,0.0003530787,0.00007260157,0.0004479997],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9974483,"threshold_uncertainty_score":0.9999833,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4224437039","doi":"10.1038/s41392-022-00972-6","title":"Signaling cascades in the failing heart and emerging therapeutic strategies","year":2022,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Basic and Applied Basic Research Foundation of Guangdong Province; Terry Fox Foundation; National Natural Science Foundation of China","keywords":"Heart failure; Medicine; Computational biology; Neuroscience; Bioinformatics; Biology; Internal medicine","retraction":null,"screen_n_in":null,"score":{"opus":0.0535648126579077,"gpt":0.3248037155696785,"spread":0.2712389029117708,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006489484,0.0003924245,0.0005119744,0.0001245651,0.0002794031,0.0001230634,0.0002158252,0.0002080291,0.0002372457],"category_scores_gemma":[0.000008180643,0.0002912422,0.0002423876,0.0002627102,0.0001349417,0.00001276612,0.00002191301,0.0004615443,7.313836e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001537154,"about_ca_system_score_gemma":0.0001632971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001875406,"about_ca_topic_score_gemma":0.000004214322,"domain_scores_codex":[0.9978693,0.0006733997,0.0003896482,0.000566348,0.0002165436,0.0002847476],"domain_scores_gemma":[0.9994749,0.00009653833,0.000113904,0.0002357274,0.00001825055,0.00006060914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001831715,0.0001768855,0.00003770219,0.001958537,0.0005133034,0.00002052045,0.002021591,0.0002296341,0.05597067,0.0002834274,0.00005578948,0.9385488],"study_design_scores_gemma":[0.0004830137,0.0002570238,0.0000082719,0.0003052178,0.0001360042,0.0001315172,0.002100123,0.00001219138,0.002002667,0.0003831081,0.9937369,0.0004439497],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01174872,0.9871548,0.0001921181,0.00007350254,0.0001545073,0.0005844251,0.00002911542,0.00002351205,0.00003924722],"genre_scores_gemma":[0.082658,0.9164005,0.00006206876,0.0002066707,0.0002556438,0.0001725911,0.0001738349,0.00005467439,0.00001602529],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9936811,"threshold_uncertainty_score":0.999954,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4289856259","doi":"10.1038/s41392-022-01059-y","title":"Human umbilical cord mesenchymal stem cells for psoriasis: a phase 1/2a, single-arm study","year":2022,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":83,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SKiN Health","funders":"National Natural Science Foundation of China","keywords":"Psoriasis; Medicine; Umbilical cord; Mesenchymal stem cell; Peripheral blood mononuclear cell; Adverse effect; Immune system; Immunology; Transplantation; Interleukin 17; Internal medicine; Psoriasis Area and Severity Index; Biomarker; Gastroenterology; Pathology; In vitro","retraction":null,"screen_n_in":null,"score":{"opus":0.0487887199434547,"gpt":0.2857586974476647,"spread":0.23696997750421,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003559982,0.0002819907,0.0003797147,0.0001555115,0.001033757,0.00002589084,0.000151352,0.0001218759,0.003438395],"category_scores_gemma":[0.000001150726,0.0002584921,0.0002058777,0.0002095783,0.0001029415,0.00008321343,0.00001645029,0.0002252294,0.00001254397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005025236,"about_ca_system_score_gemma":0.00003409898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003558248,"about_ca_topic_score_gemma":0.00001046374,"domain_scores_codex":[0.9981269,0.000531434,0.0003567775,0.0005354399,0.00008481933,0.0003646917],"domain_scores_gemma":[0.9995201,0.00008055465,0.0001036578,0.0001930398,0.00005363755,0.00004899608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005158063,0.007988072,0.0001734289,0.000008523435,0.0008462526,0.000008014965,0.002553153,0.0000121422,0.8520115,0.0001473755,0.0004180105,0.1306755],"study_design_scores_gemma":[0.05046697,0.04451916,0.0007407421,0.000007729232,0.0004717362,0.0001068375,0.01064824,0.0000152141,0.8134506,0.0005721435,0.07823739,0.0007632588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928268,0.003436649,0.000255952,0.0001375624,0.001419561,0.001449721,0.0002728039,0.0001422109,0.00005877341],"genre_scores_gemma":[0.9975167,0.00007063749,0.00004108333,0.00009709893,0.00013105,0.0006208295,0.0001824764,0.00003553718,0.001304599],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1299122,"threshold_uncertainty_score":0.9999867,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4385904643","doi":"10.1038/s41392-023-01539-9","title":"VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway","year":2023,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Sunnybrook Health Science Centre","funders":"State Key Laboratory of Ophthalmology; Novo Nordisk Fonden; National Natural Science Foundation of China-Yunnan Joint Fund; Sun Yat-sen University; National Natural Science Foundation of China","keywords":"Angiogenesis; Fibroblast growth factor receptor 1; Cancer research; MAPK/ERK pathway; In vivo; Fibroblast growth factor; Function (biology); VEGF receptors; Vascular endothelial growth factor; Biology; Medicine; Pharmacology; Chemistry; Cell biology; Signal transduction; Internal medicine; Receptor; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.01602937425335377,"gpt":0.258292156353639,"spread":0.2422627821002852,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001907646,0.0001748954,0.0001296076,0.00009850186,0.0001640101,0.00003515245,0.0001027315,0.0001462282,0.0001956031],"category_scores_gemma":[0.000009309777,0.0001641591,0.0001002181,0.0003011043,0.00008570936,0.00001197944,0.00002143446,0.000103971,0.00002029944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008972316,"about_ca_system_score_gemma":0.00004086633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001578872,"about_ca_topic_score_gemma":0.000002189778,"domain_scores_codex":[0.9987555,0.0001295796,0.000174987,0.0003981073,0.000209361,0.0003325218],"domain_scores_gemma":[0.999645,0.00001412383,0.00004635322,0.0001192025,0.00005796868,0.0001173538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001617347,0.00004278048,0.0009986139,0.00001913329,0.00008336321,0.000003057299,0.0001563927,0.00001809739,0.9860592,0.000007993459,0.001200444,0.01124916],"study_design_scores_gemma":[0.000880904,0.0003422108,0.001588454,0.00001579753,0.000003853267,0.000007372707,0.0001297663,0.00003769754,0.9843395,0.0001132322,0.01234712,0.0001940549],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965304,0.002041945,0.000624141,0.000212256,0.0001023593,0.000246514,0.00008614935,0.00006533012,0.0000909126],"genre_scores_gemma":[0.9970441,0.001432209,0.0000587468,0.00007961557,0.0001949405,0.00004606202,0.0004250478,0.00003980952,0.0006795081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01114668,"threshold_uncertainty_score":0.6694214,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2774630092","doi":"10.1038/sigtrans.2017.59","title":"Prohibitin: a potential therapeutic target in tyrosine kinase signaling","year":2017,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Research Manitoba; Health Sciences Centre Foundation","keywords":"Prohibitin; Cell biology; Biology; Signal transduction; Phosphorylation; Signal transducing adaptor protein; Tyrosine phosphorylation; Mitochondrion","retraction":null,"screen_n_in":null,"score":{"opus":0.06145277093559601,"gpt":0.3319872582345312,"spread":0.2705344872989352,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002576403,0.000398304,0.0006440705,0.0001518552,0.0002119282,0.00009496696,0.0002222622,0.0003890053,0.0002433627],"category_scores_gemma":[0.000004224783,0.0003333484,0.0003190649,0.0001186894,0.000134144,0.00001167557,0.00001378316,0.0002885364,0.000006414714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002231907,"about_ca_system_score_gemma":0.0002052358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001749187,"about_ca_topic_score_gemma":0.000004561924,"domain_scores_codex":[0.9983258,0.0001922128,0.0004335204,0.0006142784,0.0001415731,0.0002926333],"domain_scores_gemma":[0.9992328,0.000006454489,0.0002357857,0.0003754444,0.00006373785,0.00008583691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000120594,0.0001411194,0.00000523789,0.0006247816,0.0002010976,0.000008201127,0.00004409035,0.00002736588,0.05199414,0.00006173563,0.00004824279,0.9467234],"study_design_scores_gemma":[0.0008420908,0.0002184651,0.00001750139,0.0005836064,0.00008247689,0.00003986521,0.00001932421,0.00001602338,0.00688868,0.0001496574,0.9906964,0.0004458709],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007247133,0.9964404,0.00159974,0.00006728819,0.0002422746,0.0007400569,0.00006874953,0.0000184137,0.00009843276],"genre_scores_gemma":[0.02243044,0.9755651,0.0001835978,0.0000520832,0.0005585813,0.0002197269,0.000521111,0.00006699227,0.0004023804],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9906482,"threshold_uncertainty_score":0.9999118,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4214633714","doi":"10.1038/s41392-022-00906-2","title":"Asymmetric, amphiphilic RGD conjugated phthalocyanine for targeted photodynamic therapy of triple negative breast cancer","year":2022,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Photodynamic Therapy Research Studies","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Peking University; National Natural Science Foundation of China","keywords":"Photodynamic therapy; Triple-negative breast cancer; Photosensitizer; Cancer research; Phototoxicity; Chemistry; Targeted therapy; Phthalocyanine; Cytotoxicity; Biophysics; Cancer; Medicine; In vitro; Breast cancer; Biochemistry; Photochemistry; Biology; Internal medicine; Organic chemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.02304300181852613,"gpt":0.2983303512829871,"spread":0.275287349464461,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005368938,0.0003906636,0.0007879759,0.0005874874,0.0005088475,0.00001835581,0.0001758133,0.00009857215,0.003417668],"category_scores_gemma":[0.0000208952,0.0003329381,0.0003116401,0.001384556,0.0003400407,0.0001342032,0.00002192307,0.0004666906,8.76988e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002077049,"about_ca_system_score_gemma":0.0002542517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007066235,"about_ca_topic_score_gemma":0.00002751259,"domain_scores_codex":[0.9974387,0.0002822263,0.0005375073,0.0005852152,0.000628862,0.0005274887],"domain_scores_gemma":[0.9987364,0.0001822682,0.0002282842,0.0002489625,0.0004107022,0.0001934289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01935969,0.000841911,0.0003401453,0.00006146003,0.001536172,0.000007646081,0.001429581,0.00009338,0.9439585,0.00008203815,0.0003717132,0.03191772],"study_design_scores_gemma":[0.04255369,0.007133846,0.03287305,0.00006215624,0.0001142631,0.0002510514,0.001863565,0.002935501,0.899636,0.001693082,0.01013688,0.0007469155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9785975,0.01267732,0.0002736933,0.002540743,0.0004225594,0.003256735,0.002016489,0.0001470997,0.00006786323],"genre_scores_gemma":[0.9797119,0.01761035,0.0001379486,0.0004932834,0.0001508007,0.001145618,0.0002742306,0.00008212212,0.0003937653],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04432254,"threshold_uncertainty_score":0.9999123,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4321166935","doi":"10.1038/s41392-022-01268-5","title":"B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin","year":2023,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Alberta","funders":"Wuhan Science and Technology Project; Hubei University; Hubei University of Technology; National Natural Science Foundation of China","keywords":"Wnt signaling pathway; Phosphorylation; Pancreatic cancer; Catenin; Cancer research; Receptor tyrosine kinase; Tyrosine; Tyrosine kinase; Signal transduction; Tyrosine phosphorylation; Biology; Cell biology; Chemistry; Cancer; Biochemistry; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.0127864949625567,"gpt":0.2378651535204363,"spread":0.2250786585578796,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001389449,0.0002239226,0.000177449,0.0000912006,0.000176631,0.00003723901,0.00006228314,0.0001374383,0.0001373994],"category_scores_gemma":[0.00001292653,0.0001951291,0.00006625736,0.0004961321,0.00007901643,0.00002688939,0.000007647809,0.00009131283,0.00001459396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002969532,"about_ca_system_score_gemma":0.00005801996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008921987,"about_ca_topic_score_gemma":0.00002254514,"domain_scores_codex":[0.9988468,0.00007584401,0.0002403611,0.0004120892,0.0001695758,0.0002553659],"domain_scores_gemma":[0.9995496,0.00003111167,0.0001100929,0.0001422969,0.0001051329,0.00006171784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008838365,0.00003888077,0.00233474,0.00001544873,0.0001542992,0.000002035754,0.000351799,0.001882499,0.9876679,0.00001476659,0.0001727503,0.006481038],"study_design_scores_gemma":[0.001804806,0.0005195956,0.009290982,0.00004404944,0.000035488,0.00003426669,0.000312708,0.001736574,0.9796337,0.0001071091,0.006184996,0.0002957351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931856,0.0029634,0.002744197,0.0003252559,0.0002690835,0.0003159731,0.00002282532,0.0001200121,0.00005359407],"genre_scores_gemma":[0.9935883,0.004323114,0.0003170359,0.00007121138,0.000275453,0.00005625398,0.001043955,0.00005009315,0.0002745574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008034217,"threshold_uncertainty_score":0.7957135,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4296796569","doi":"10.1038/s41392-022-01157-x","title":"Clusterin transduces Alzheimer-risk signals to amyloidogenesis","year":2022,"lang":"en","type":"letter","venue":"Signal Transduction and Targeted Therapy","topic":"Clusterin in disease pathology","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"Zhengzhou University; National Natural Science Foundation of China; First Affiliated Hospital of Zhengzhou University; Guangdong Provincial People's Hospital; University of British Columbia; Capital Medical University","keywords":"Clusterin; Alzheimer's disease; Biology; Neuroscience; Cell biology; Medicine; Disease; Genetics; Pathology; Apoptosis","retraction":null,"screen_n_in":null,"score":{"opus":0.04420614918602479,"gpt":0.2879817266671192,"spread":0.2437755774810945,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003910749,0.0007623784,0.00107687,0.0006983112,0.0003672775,0.00005886527,0.0002678905,0.0007132373,0.0293881],"category_scores_gemma":[0.00001294216,0.0007298756,0.0005419536,0.000543248,0.0002049427,0.00009057004,0.00003665685,0.001878245,0.00007938192],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008977334,"about_ca_system_score_gemma":0.0001651467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008200428,"about_ca_topic_score_gemma":0.000005893872,"domain_scores_codex":[0.9958968,0.0006973758,0.0007126101,0.001235432,0.0007504607,0.0007073546],"domain_scores_gemma":[0.9985778,0.0001620017,0.0002070262,0.0005706238,0.0001275068,0.0003550456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01160525,0.0007424506,0.0005231199,0.0006388095,0.005183594,0.002483435,0.005255818,0.0004933598,0.2043731,0.000006478003,0.6514031,0.1172916],"study_design_scores_gemma":[0.002986552,0.002434893,0.0008999332,0.00006614073,0.001016786,0.000672068,0.0001573729,0.00004223834,0.01633333,0.0002001462,0.9743178,0.0008726998],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.2357321,0.02535299,0.002470145,0.7239204,0.003220174,0.005212493,0.00224703,0.0008326526,0.001012014],"genre_scores_gemma":[0.1471255,0.009864674,0.00157744,0.826809,0.00757855,0.001441015,0.002383336,0.000555028,0.002665439],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.3229148,"threshold_uncertainty_score":0.9995152,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4299878889","doi":"10.1038/s41392-022-01148-y","title":"Glutamate and GABAA receptor crosstalk mediates homeostatic regulation of neuronal excitation in the mammalian brain","year":2022,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":41,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Coastal Health","funders":"Canadian Institutes of Health Research; Natural Science Foundation of Chongqing; Ministry of Science and Technology, Taiwan; Chongqing Medical University; National Science Council; Chongqing Municipal Education Commission; Heart and Stroke Foundation of British Columbia and Yukon; National Natural Science Foundation of China; Government of Canada; China Medical University; Heart and Stroke Foundation of Canada","keywords":"Glutamate receptor; Long-term potentiation; Inhibitory postsynaptic potential; Excitatory postsynaptic potential; GABAA receptor; Neuroscience; NMDA receptor; Chemistry; Biology; Pharmacology; Receptor; Biochemistry","retraction":null,"screen_n_in":null,"score":{"opus":0.03829312165082265,"gpt":0.3007580992405501,"spread":0.2624649775897275,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005594474,0.0001055349,0.0001151322,0.0002054897,0.0003938281,0.00004142467,0.0001490554,0.00002256378,0.0005945075],"category_scores_gemma":[0.00004467166,0.0000842309,0.00002996644,0.0006430866,0.0003721525,0.0002294834,0.00001621143,0.0002666278,0.000001348841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000100141,"about_ca_system_score_gemma":0.00003255186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001132323,"about_ca_topic_score_gemma":0.000001741164,"domain_scores_codex":[0.9978525,0.0009896526,0.0002147127,0.0003320275,0.0004049158,0.0002061584],"domain_scores_gemma":[0.9993572,0.0004258586,0.00007471831,0.0000788807,0.0000188116,0.00004450549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004329759,0.00009782713,0.0004319999,0.0000116126,0.000001496192,0.000006569166,0.002483674,0.00009313459,0.9931002,0.0003538286,0.00006528282,0.002921419],"study_design_scores_gemma":[0.002057376,0.00120507,0.06431385,0.000003933091,0.000004080269,0.00008041373,0.000872644,0.001339873,0.9245563,0.002948917,0.002463935,0.0001535792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944746,0.0001450872,0.00002798351,0.004678096,0.0002027163,0.0003941223,0.00003872261,0.00001912189,0.00001957271],"genre_scores_gemma":[0.9979101,0.0005298149,0.000009882415,0.001371861,0.00002769467,0.00005932901,0.000004888218,0.00001132605,0.00007509415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06854385,"threshold_uncertainty_score":0.650944,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3128681620","doi":"10.1038/s41392-020-00410-5","title":"Inhibition of cystathionine β-synthase promotes apoptosis and reduces cell proliferation in chronic myeloid leukemia","year":2021,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia Hospital; University of British Columbia","funders":"Chongqing Medical University","keywords":"Cystathionine beta synthase; Myeloid leukemia; Apoptosis; K562 cells; Cancer research; Cell growth; Leukemia; Bone marrow; Chronic myelogenous leukemia; Biology; Myeloid; Chemistry; Molecular biology; Immunology; Biochemistry; Enzyme","retraction":null,"screen_n_in":null,"score":{"opus":0.01584642555147811,"gpt":0.2492557133127846,"spread":0.2334092877613065,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001563524,0.0001866231,0.0003123124,0.000165486,0.0000698298,0.0000188149,0.00001711236,0.0001277274,0.0004278795],"category_scores_gemma":[0.00001054662,0.0001683485,0.00005743302,0.0003220662,0.00009941251,0.0001717609,0.00000544935,0.0001913415,0.000001543914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004165989,"about_ca_system_score_gemma":0.0006451341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006237951,"about_ca_topic_score_gemma":0.00001530763,"domain_scores_codex":[0.9987993,0.0001017526,0.0003496898,0.0003604986,0.0002011611,0.0001875914],"domain_scores_gemma":[0.9995597,0.00003095845,0.00008985979,0.0001170403,0.0001098297,0.00009258373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004907323,0.0002446832,0.0005549446,0.0002024112,0.00006129243,0.00001579579,0.001504822,0.0000389363,0.9754901,0.00002884098,0.00001472927,0.02135272],"study_design_scores_gemma":[0.007686269,0.0008083283,0.002462153,0.0002027599,0.00004654894,0.00007780414,0.0003507791,0.0006044744,0.9872781,0.0001836362,0.0001611808,0.0001379353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926218,0.005721964,0.0001921576,0.000646779,0.0000621053,0.0005551219,0.00001700455,0.00003844005,0.0001446146],"genre_scores_gemma":[0.9926895,0.006007595,0.0006915557,0.00006420746,0.0001146904,0.00005743605,0.0001898217,0.00002256594,0.0001625523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02121479,"threshold_uncertainty_score":0.6865054,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4408082142","doi":"10.1038/s41392-025-02158-2","title":"Neoleukin-2/15-armored CAR-NK cells sustain superior therapeutic efficacy in solid tumors via c-Myc/NRF1 activation","year":2025,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":37,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Infection and Immunity","funders":"National Natural Science Foundation of China","keywords":"Cancer research; Tumor microenvironment; Chimeric antigen receptor; Adoptive cell transfer; Immunology; Biology; Immune system; Immunotherapy; T cell","retraction":null,"screen_n_in":null,"score":{"opus":0.00986634598711917,"gpt":0.2418641921948026,"spread":0.2319978462076834,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002515628,0.0003137136,0.0003793629,0.0004864303,0.0002903883,0.0000447524,0.000124046,0.0003077515,0.003103202],"category_scores_gemma":[0.000008667812,0.0002897502,0.0001492864,0.0004873135,0.0001718952,0.0002731536,0.00001021489,0.0005637237,0.00006596946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001245156,"about_ca_system_score_gemma":0.0001018966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002893099,"about_ca_topic_score_gemma":0.00001500383,"domain_scores_codex":[0.9981875,0.0003902542,0.0005025761,0.0004554089,0.00005992398,0.0004043085],"domain_scores_gemma":[0.9994453,0.0001111324,0.0001038345,0.0001997207,0.0001114211,0.00002862342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001980041,0.0003640455,0.0001963264,0.00002218727,0.0001993296,0.000002013654,0.001280978,0.0001580747,0.957332,0.000226765,0.0004043576,0.0378339],"study_design_scores_gemma":[0.004687833,0.0003523623,0.007459149,0.00006329528,0.00002671958,0.00001868264,0.001327446,0.0001564651,0.9501045,0.0002897767,0.03522601,0.0002877521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836301,0.003817975,0.007132051,0.001017072,0.002928421,0.000793743,0.000004622395,0.0001820543,0.0004939431],"genre_scores_gemma":[0.9938294,0.0006773591,0.00001887939,0.0008750588,0.00005433686,0.00005250329,0.0001514286,0.00002792451,0.00431309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03754615,"threshold_uncertainty_score":0.9999555,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4404580565","doi":"10.1038/s41392-024-02028-3","title":"Remolding the tumor microenvironment by bacteria augments adoptive T cell therapy in advanced-stage solid tumors","year":2024,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"Zhejiang University; Tianjin University; East China Normal University; National Natural Science Foundation of China","keywords":"Stage (stratigraphy); Tumor microenvironment; Solid tumor; Cancer research; Bacteria; Pathology; Biology; Medicine; Tumor cells; Cancer; Internal medicine; Genetics","retraction":null,"screen_n_in":null,"score":{"opus":0.009941144038593787,"gpt":0.2591646144530536,"spread":0.2492234704144598,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001227016,0.0001914312,0.0001251953,0.00005055777,0.000105864,0.00006073544,0.00009448155,0.00004970566,0.0004004683],"category_scores_gemma":[8.034413e-7,0.0001363153,0.00007693204,0.0001085532,0.00009255557,0.00001495493,0.00001163327,0.0001445314,0.000005916762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004372688,"about_ca_system_score_gemma":0.00004368204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007303787,"about_ca_topic_score_gemma":0.00001504661,"domain_scores_codex":[0.9989269,0.00009128783,0.0001663157,0.0003994293,0.000135916,0.0002801841],"domain_scores_gemma":[0.9997377,0.000008158874,0.00002967427,0.0001378242,0.00001158033,0.00007509222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006821354,0.0001267298,0.0002992595,0.00001079009,0.00009000919,0.00001409666,0.000272769,0.00005174004,0.9783002,0.000004279391,0.0002570014,0.01989095],"study_design_scores_gemma":[0.001687714,0.0007736812,0.001176741,0.00002203421,0.000003838318,0.00001009223,0.0002262714,0.00004669534,0.9228497,0.00004429654,0.07300283,0.0001560665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9763753,0.02236526,0.0002268033,0.0002408314,0.0001263706,0.000458375,0.0001082003,0.00001600326,0.00008280921],"genre_scores_gemma":[0.9809996,0.01773195,0.00008537145,0.0001951665,0.00008297908,0.00008950574,0.0001769002,0.00003032333,0.0006081913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07274583,"threshold_uncertainty_score":0.5558775,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4291019935","doi":"10.1038/s41392-022-01067-y","title":"Multi-omics characterization and therapeutic liability of ferroptosis in melanoma","year":2022,"lang":"en","type":"letter","venue":"Signal Transduction and Targeted Therapy","topic":"Ferroptosis and cancer prognosis","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SKiN Health","funders":"National Key Research and Development Program of China; China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"Omics; Melanoma; Computational biology; Medicine; Biology; Bioinformatics; Cancer research","retraction":null,"screen_n_in":null,"score":{"opus":0.03277231402929782,"gpt":0.2626254889972294,"spread":0.2298531749679316,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002280471,0.0002962339,0.0006136947,0.0002729604,0.00007853003,0.00001813069,0.00006541466,0.0003796994,0.001661503],"category_scores_gemma":[0.000003273189,0.0002644116,0.0001358781,0.0002849113,0.000148429,0.00006336534,0.00001000117,0.0008983611,4.963463e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007194219,"about_ca_system_score_gemma":0.00007617778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008170172,"about_ca_topic_score_gemma":0.000003377723,"domain_scores_codex":[0.9983371,0.000217397,0.000453638,0.000490638,0.0002750855,0.0002261047],"domain_scores_gemma":[0.9994786,0.00003792965,0.0001645852,0.0001934366,0.0000722421,0.00005314721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00378767,0.001204347,0.05339238,0.001583578,0.0009501977,0.00003745554,0.00481164,0.00001141885,0.772017,0.00002515352,0.00107478,0.1611044],"study_design_scores_gemma":[0.01214796,0.00426756,0.2724961,0.0002874739,0.0004582751,0.0001033537,0.0005530014,0.001343047,0.08922748,0.0001430629,0.6177955,0.001177187],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8873698,0.004378212,0.0003668435,0.106077,0.0003259289,0.001199382,0.0002039873,0.00005424452,0.00002460298],"genre_scores_gemma":[0.9147867,0.01384819,0.000291281,0.06892639,0.0004616364,0.0002413764,0.001093834,0.00008788535,0.0002627252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6827895,"threshold_uncertainty_score":0.9999808,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4405877673","doi":"10.1038/s41392-024-02076-9","title":"Malate initiates a proton-sensing pathway essential for pH regulation of inflammation","year":2024,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Neurological Disorders and Stroke; Army Medical University; Centre Scientifique et Technique du Bâtiment; National Institutes of Health; York University; Southwest Hospital; Fudan University; School of Pharmacy, Fudan University; National Natural Science Foundation of China; Chongqing Medical University; Wuhan University; NYU Langone Medical Center","keywords":"Cytosol; Biochemistry; Malate dehydrogenase; Chemistry; Signal transduction; Inflammation; Metabolite; In vitro; Downregulation and upregulation; Cell biology; Biology; Enzyme","retraction":null,"screen_n_in":null,"score":{"opus":0.01253303796872893,"gpt":0.2486844915583173,"spread":0.2361514535895884,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002038123,0.0001076551,0.0001112992,0.00007741251,0.00006819163,0.00003461354,0.00002874512,0.00009769407,0.00004434231],"category_scores_gemma":[0.000006557188,0.00009697486,0.00008705536,0.00009223898,0.00004580302,0.00001660363,0.000003358296,0.00004719367,4.721087e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002902226,"about_ca_system_score_gemma":0.00003985086,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000543277,"about_ca_topic_score_gemma":0.000001090979,"domain_scores_codex":[0.9993416,0.00004205437,0.000207506,0.0002156563,0.00008133425,0.0001118602],"domain_scores_gemma":[0.9997594,0.00001238281,0.00004749758,0.00006937041,0.00008184479,0.00002950586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003120085,0.00001110365,0.00002205995,0.00009742846,0.00006900489,2.517671e-7,0.0003537588,0.0001612541,0.9597953,0.0004361432,0.00000859721,0.03873312],"study_design_scores_gemma":[0.0007184566,0.00015443,0.0002359727,0.00004026606,0.00001627226,0.000007967681,0.00005509528,0.003064734,0.9846506,0.001346887,0.009597972,0.0001114152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.932431,0.003143915,0.06343932,0.0001013468,0.0002862988,0.000511857,0.00002029306,0.00002968281,0.0000362945],"genre_scores_gemma":[0.9975245,0.0006424663,0.0008455998,0.00002028744,0.0006951522,0.00002851669,0.000180379,0.00002088749,0.00004219254],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06509353,"threshold_uncertainty_score":0.395452,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2266260677","doi":"10.1038/sigtrans.2015.2","title":"Intravenous immune globulin suppresses angiogenesis in mice and humans","year":2016,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"","funders":"National Center for Research Resources; National Institute of General Medical Sciences; National Eye Institute; National Heart, Lung, and Blood Institute; Institute of Genetics; National Institutes of Health; Ellison Medical Foundation; American Heart Association; Associazione Italiana per la Ricerca sul Cancro; Arnold and Mabel Beckman Initiative for Macular Research; Fundação Champalimaud; Alcon Japan; Ministério da Saúde; Research to Prevent Blindness; John Templeton Foundation; International Retinal Research Foundation; U.S. Department of Defense","keywords":"Medicine; Antibody; Immunology; Neovascularization; Angiogenesis; Immune system; Polyclonal antibodies; Potency; Pharmacology; Drug; Cancer research; In vitro; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.02124309413872232,"gpt":0.2723522101251205,"spread":0.2511091159863982,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001498711,0.0001430902,0.0002368345,0.0001438231,0.00008532924,0.00001456507,0.00004334582,0.00007961392,0.001206367],"category_scores_gemma":[0.000005694685,0.0000893643,0.00006364492,0.0001468747,0.000180652,0.00008317371,0.000007371991,0.00009887503,0.00000871872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001538946,"about_ca_system_score_gemma":0.00003165701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002577212,"about_ca_topic_score_gemma":0.00002894997,"domain_scores_codex":[0.999056,0.00006827494,0.0002065405,0.0002543283,0.0001692776,0.0002455383],"domain_scores_gemma":[0.9996637,0.00006757214,0.00002387058,0.00007554076,0.00004976935,0.0001196028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001676396,0.0001579838,0.008966109,0.00004445107,0.00008882142,0.00003156535,0.000539516,5.779609e-7,0.8889102,0.000304342,0.00003703628,0.09924294],"study_design_scores_gemma":[0.005779574,0.001276503,0.3241727,0.0001687718,0.00003024034,0.0002304032,0.0002419127,0.00002521248,0.6410404,0.001379636,0.02534617,0.0003084631],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825851,0.01179351,0.000185558,0.004841845,0.00006333726,0.0002476517,0.00002706356,0.00003007007,0.0002258679],"genre_scores_gemma":[0.9790717,0.01945163,0.0001905149,0.0001578201,0.0001411223,0.00001460248,0.00001314741,0.00001545238,0.0009439933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3152066,"threshold_uncertainty_score":0.9997067,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4399711928","doi":"10.1038/s41392-024-01862-9","title":"Targeted therapy for capillary-venous malformations","year":2024,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Vascular Malformations and Hemangiomas","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"Agence Nationale de la Recherche","keywords":"Medicine; Venous malformation; Vascular malformation; Magnetic resonance imaging; Venous thrombosis; Pathology; Internal medicine; Radiology; Surgery; Thrombosis","retraction":null,"screen_n_in":null,"score":{"opus":0.02318276090772895,"gpt":0.2715170917828398,"spread":0.2483343308751108,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002222614,0.000205275,0.000257388,0.000294391,0.0002789259,0.00008473721,0.000047023,0.0001288279,0.001335501],"category_scores_gemma":[0.000003258048,0.0001604018,0.0002825598,0.000355032,0.00006595511,0.0003049471,0.000002652999,0.0001656992,0.00002950338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003041954,"about_ca_system_score_gemma":0.00009434766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001663166,"about_ca_topic_score_gemma":0.000002401858,"domain_scores_codex":[0.9989516,0.00003090762,0.0003049001,0.0002540562,0.0001946767,0.0002638959],"domain_scores_gemma":[0.999528,0.00003346812,0.00003210255,0.000157047,0.0001222111,0.0001271757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00240506,0.001444846,0.0002645066,0.0009487538,0.003112304,0.00004500686,0.02056774,0.0001901629,0.4494748,0.02715558,0.00951078,0.4848805],"study_design_scores_gemma":[0.008099304,0.00300908,0.004434829,0.0001712024,0.0002049059,0.000657362,0.001300678,0.01059391,0.1222345,0.005378074,0.8432544,0.0006617584],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8381273,0.08624684,0.06175546,0.007991399,0.0009421518,0.002789004,0.0001371162,0.0008160297,0.001194773],"genre_scores_gemma":[0.9863918,0.009554682,0.001874047,0.0005735986,0.0003804362,0.0001806217,0.0004085827,0.00004854529,0.000587659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8337436,"threshold_uncertainty_score":0.9995774,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4313251504","doi":"10.1038/s41392-022-01239-w","title":"SARS-CoV-2 hijacks cellular kinase CDK2 to promote viral RNA synthesis","year":2022,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"McGill University; Jewish General Hospital","funders":"Fundamental Research Funds for the Central Universities; National Medical Research Council; National Natural Science Foundation of China","keywords":"Biology; RNA; Kinase; Cyclin-dependent kinase 2; Virology; Coronaviridae; Viral replication; RNA-dependent RNA polymerase; Cell biology; Subgenomic mRNA; Coronavirus disease 2019 (COVID-19); Genetics; Virus; Protein kinase A; Gene; Disease","retraction":null,"screen_n_in":null,"score":{"opus":0.03699022197621208,"gpt":0.3044330731505513,"spread":0.2674428511743392,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004895875,0.0002703797,0.0003690264,0.0003672624,0.0004068163,0.00004750899,0.000165487,0.00009335119,0.0006354766],"category_scores_gemma":[0.00001855191,0.0002472193,0.0001984238,0.0005967396,0.0000981876,0.0001096369,0.00002777674,0.0005012248,0.00004348503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001187598,"about_ca_system_score_gemma":0.0001498344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001571231,"about_ca_topic_score_gemma":0.000004638448,"domain_scores_codex":[0.9977896,0.0002124526,0.0003056447,0.0005580303,0.000666306,0.0004680185],"domain_scores_gemma":[0.9994288,0.00004476259,0.00004840528,0.0002974431,0.0000938533,0.00008672612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002310249,0.0003901565,0.0002284338,0.00003995966,0.0001469134,0.0001130846,0.001099512,0.000003687356,0.9402556,0.00008260131,0.0002980724,0.05503176],"study_design_scores_gemma":[0.00148793,0.001008775,0.0001328517,0.00001615131,0.00003193699,0.00004379787,0.0002178994,0.0001912344,0.7452354,0.0003101489,0.2511139,0.0002099428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926679,0.00196611,0.001110377,0.002166844,0.000271919,0.0009481671,0.00003937018,0.0001676149,0.0006617477],"genre_scores_gemma":[0.9807324,0.00004792276,0.0002901861,0.01819383,0.0002816401,0.0003012009,0.0000119794,0.00006011494,0.00008075844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2508158,"threshold_uncertainty_score":0.999998,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4379364758","doi":"10.1038/s41392-023-01431-6","title":"CNTNAP2 intracellular domain (CICD) generated by γ-secretase cleavage improves autism-related behaviors","year":2023,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Autism Spectrum Disorder Research","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of British Columbia","funders":"National Natural Science Foundation of China-Yunnan Joint Fund; National Natural Science Foundation of China","keywords":"Transmembrane domain; Amyloid precursor protein; Transmembrane protein; Neuroscience; Biology; Prefrontal cortex; Cell biology; Gene; Genetics; Receptor; Medicine; Internal medicine; Alzheimer's disease","retraction":null,"screen_n_in":null,"score":{"opus":0.02091473214823582,"gpt":0.2650233299637968,"spread":0.244108597815561,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000417337,0.0003502569,0.0002938721,0.0003550854,0.0005579629,0.0001442755,0.0002722722,0.0002338218,0.001847949],"category_scores_gemma":[0.00001401635,0.0003282579,0.0001248931,0.001624555,0.0004007328,0.0003373226,0.00002501984,0.0005957327,0.0001966549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004036774,"about_ca_system_score_gemma":0.00006108563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008615171,"about_ca_topic_score_gemma":0.000005196262,"domain_scores_codex":[0.9969373,0.0004813116,0.0004307253,0.0008552198,0.0005469412,0.0007484435],"domain_scores_gemma":[0.999263,0.00007559454,0.00009412774,0.0002810252,0.0000129656,0.0002732869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001912729,0.0001708968,0.00006315536,0.00001008166,0.00002857094,0.00006900629,0.001020717,0.00002538406,0.9857491,0.003076907,0.000602293,0.008992586],"study_design_scores_gemma":[0.002264169,0.0004544395,0.001093708,0.000008289076,0.00001233169,0.00003627961,0.0001812158,0.001628797,0.9775051,0.01043595,0.005959447,0.0004202031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913651,0.00152388,0.0007498192,0.004147048,0.0003484249,0.0007706226,0.0001531167,0.0007512869,0.0001906949],"genre_scores_gemma":[0.9950007,0.003426195,0.00005585869,0.000213167,0.0000394153,0.00008064122,0.000177356,0.00008514028,0.0009215443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008572383,"threshold_uncertainty_score":0.999917,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4407778494","doi":"10.1038/s41392-025-02133-x","title":"Precise targeting of transcriptional co-activators YAP/TAZ annihilates chemoresistant brCSCs by alteration of their mitochondrial homeostasis","year":2025,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Natural Sciences and Engineering Research Council of Canada; All-India Institute of Medical Sciences; University of Calcutta; Department of Science and Technology, Ministry of Science and Technology, India","keywords":"Homeostasis; Cancer research; Mitochondrion; Medicine; Cell biology; Chemistry; Biology","retraction":null,"screen_n_in":null,"score":{"opus":0.009128353143895129,"gpt":0.2422732122414935,"spread":0.2331448590975983,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001962755,0.0002237343,0.0002894673,0.0001100215,0.0001269292,0.00001891958,0.0001052579,0.0001948154,0.000147345],"category_scores_gemma":[0.00001171712,0.0001991803,0.000174915,0.000191478,0.0001690015,0.00001647326,0.00000486726,0.0001180961,3.356839e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000103178,"about_ca_system_score_gemma":0.00009206653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002192113,"about_ca_topic_score_gemma":0.00000174168,"domain_scores_codex":[0.9987075,0.0001299388,0.000442433,0.0003606106,0.0001679896,0.0001914792],"domain_scores_gemma":[0.9994694,0.00002704297,0.0001418395,0.0001433894,0.0001561066,0.00006222458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001463201,0.0001954252,0.0001844872,0.00005825625,0.0002189117,2.332145e-7,0.0004784336,0.00009130259,0.990267,0.00007954738,0.0002783079,0.006684867],"study_design_scores_gemma":[0.001589859,0.0003832022,0.0002364581,0.00004104905,0.00002207105,0.000001757615,0.0002511725,0.00009226312,0.9821093,0.0002266718,0.01486717,0.0001789882],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9783137,0.008341319,0.01212172,0.0001634799,0.0002468833,0.0002964431,0.0003814768,0.00002048522,0.0001144636],"genre_scores_gemma":[0.9964462,0.001940712,0.0005598958,0.00005814217,0.0001407881,0.00002265726,0.0006749302,0.00002057627,0.0001361266],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01813244,"threshold_uncertainty_score":0.8122336,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3132116659","doi":"10.1038/s41392-021-00463-0","title":"PD-L1 regulates genomic stability via interaction with cohesin-SA1 in the nucleus","year":2021,"lang":"en","type":"letter","venue":"Signal Transduction and Targeted Therapy","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Toronto","funders":"","keywords":"Cohesin; Nucleus; Biology; Cell biology; Genetics; DNA","retraction":null,"screen_n_in":null,"score":{"opus":0.0281207187098384,"gpt":0.2459181359221369,"spread":0.2177974172122985,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003729776,0.0003810656,0.0004912585,0.0001742438,0.0001346762,0.0000823458,0.0001107916,0.0004266853,0.002264947],"category_scores_gemma":[0.000002334415,0.0002446897,0.0002083649,0.0003606133,0.0002505161,0.0001223578,0.000003911599,0.001330251,0.000003560923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001622188,"about_ca_system_score_gemma":0.0001429177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003224637,"about_ca_topic_score_gemma":0.00007077228,"domain_scores_codex":[0.9979901,0.0003719983,0.0004143363,0.000553707,0.0003594988,0.0003103782],"domain_scores_gemma":[0.9992418,0.000105736,0.000145618,0.0003657884,0.0001000506,0.00004094982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0297072,0.0007330413,0.001582079,0.0006012142,0.002017571,0.0006139246,0.008784731,0.00001320808,0.8318161,0.00000644985,0.03469624,0.08942818],"study_design_scores_gemma":[0.007179088,0.001680525,0.0250647,0.0003687741,0.0002033725,0.001110013,0.001542666,0.00005358325,0.06633139,0.0001694199,0.8956563,0.0006401084],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7381625,0.007383519,0.0002525686,0.2518746,0.0005768459,0.001319369,0.00005061189,0.00008394972,0.0002959917],"genre_scores_gemma":[0.8037411,0.005236679,0.0002072457,0.1876038,0.001832089,0.0001133418,0.0008140479,0.0001015257,0.0003501693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8609601,"threshold_uncertainty_score":0.9986471,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4392771886","doi":"10.1038/s41392-024-01752-0","title":"Eosinophils promote CD8+ T cell memory generation to potentiate anti-bacterial immunity","year":2024,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Institute of Infection and Immunity","funders":"National Natural Science Foundation of China","keywords":"Cytotoxic T cell; CD8; Immunology; Eosinophil; Adoptive cell transfer; Biology; Immune system; T cell; Memory T cell; Cell biology; In vitro","retraction":null,"screen_n_in":null,"score":{"opus":0.01720437070318525,"gpt":0.2312946908646801,"spread":0.2140903201614949,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002418483,0.0002286094,0.0002062618,0.000236033,0.0003323481,0.0001164616,0.00007931671,0.0002087059,0.007722575],"category_scores_gemma":[0.000003423431,0.0002014873,0.0001239822,0.0001697195,0.00006772122,0.0003226695,0.000009620584,0.0003663022,0.0005043645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003372863,"about_ca_system_score_gemma":0.00004163036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007816234,"about_ca_topic_score_gemma":0.000003245856,"domain_scores_codex":[0.998761,0.0002469529,0.0003040395,0.0003784482,0.00005088181,0.000258696],"domain_scores_gemma":[0.9996642,0.00001840964,0.00004380862,0.0001553578,0.00007883222,0.00003940542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003676673,0.0001202419,0.000004288039,0.00001962943,0.0001356339,0.00000253344,0.000991934,0.00003557031,0.9692476,0.00007544633,0.002449157,0.02655027],"study_design_scores_gemma":[0.000870837,0.0004208939,0.0002527678,0.00002201034,0.00002733235,0.00005786885,0.0001291214,0.00008616841,0.8462026,0.00004330503,0.1516794,0.0002077671],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9770283,0.005624969,0.003753795,0.0007845407,0.01153879,0.0004531086,0.00001687296,0.0002678451,0.0005317571],"genre_scores_gemma":[0.9930284,0.0008069007,0.00006925054,0.000271761,0.0003449699,0.00002902385,0.0004455126,0.00003187484,0.004972318],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1492302,"threshold_uncertainty_score":0.9931845,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W3122124144","doi":"10.1038/s41392-020-00379-1","title":"Lysophosphatidic acid mediates the pathogenesis of psoriasis by activating keratinocytes through LPAR5","year":2021,"lang":"en","type":"letter","venue":"Signal Transduction and Targeted Therapy","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"SKiN Health","funders":"International Cooperation and Exchange Programme; National Natural Science Foundation of China","keywords":"Psoriasis; Pathogenesis; Lysophosphatidic acid; Dermatology; Keratinocyte; Medicine; Immunology; Biology; Genetics; Internal medicine; Cell culture","retraction":null,"screen_n_in":null,"score":{"opus":0.01673874889177419,"gpt":0.2330772937412701,"spread":0.2163385448494959,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002474276,0.0004190917,0.0004801005,0.00004425438,0.0002474517,0.00006152944,0.0002314474,0.0006257519,0.0003635924],"category_scores_gemma":[0.00003283725,0.0003104431,0.0002791983,0.0002051007,0.0001908769,0.00001480899,0.00002254838,0.0004966651,8.236097e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007146328,"about_ca_system_score_gemma":0.0001043756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005408714,"about_ca_topic_score_gemma":0.000001643588,"domain_scores_codex":[0.9979573,0.0003313607,0.0004586327,0.0005904922,0.0003318342,0.0003303508],"domain_scores_gemma":[0.9990886,0.00007217829,0.0002860875,0.0003392048,0.000169954,0.00004399316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009338986,0.00003393,0.00004221659,0.00006363326,0.0003915643,0.000003620576,0.000609813,0.0000107256,0.9492453,0.000007123588,0.04194672,0.007551949],"study_design_scores_gemma":[0.0006327038,0.0001020528,0.0000448857,0.00002943979,0.00005531203,0.000009842698,0.0002593773,0.000006935399,0.7310706,0.00008132788,0.2674491,0.0002584945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.551446,0.3765051,0.005894414,0.062013,0.002430707,0.0008867502,0.0006145645,0.00006694447,0.0001425632],"genre_scores_gemma":[0.7124456,0.122012,0.002164191,0.1443299,0.01261108,0.0001682334,0.00544162,0.0002613489,0.0005660563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2544931,"threshold_uncertainty_score":0.9999348,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4223434313","doi":"10.1038/s41392-022-00927-x","title":"LSD1 is required for euchromatic origin firing and replication timing","year":2022,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false},"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Origin recognition complex; Euchromatin; Chromatin; Origin of replication; Pre-replication complex; Control of chromosome duplication; Biology; DNA replication; Replication timing; Licensing factor; Genetics; Eukaryotic DNA replication; SeqA protein domain; DNA replication factor CDT1; Cell biology; DNA; Heterochromatin","retraction":null,"screen_n_in":null,"score":{"opus":0.04148904896988815,"gpt":0.2963178802413296,"spread":0.2548288312714415,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002406242,0.00008538683,0.00007913193,0.00003901014,0.0002739539,0.00001863904,0.00003991734,0.00004280895,0.00008633642],"category_scores_gemma":[0.000005994616,0.00008911798,0.00003873435,0.00006341613,0.00002806155,0.000005479983,0.000009450307,0.00004670601,2.323514e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008252849,"about_ca_system_score_gemma":0.00001715134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005636836,"about_ca_topic_score_gemma":0.000001022332,"domain_scores_codex":[0.9993392,0.00004841078,0.0001375264,0.0002935095,0.00007611584,0.0001052127],"domain_scores_gemma":[0.9997306,0.00001091817,0.00005328135,0.0001363549,0.00003134918,0.00003745309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001234591,0.00002319268,0.0002669633,0.00001311815,0.00002966253,1.00302e-7,0.0003247432,0.000102999,0.95908,0.00006230592,0.00006198945,0.03991141],"study_design_scores_gemma":[0.001145243,0.0006297889,0.001173413,0.000003998867,0.0000140335,0.000006363908,0.0001434411,0.00137567,0.9195654,0.002433834,0.07334,0.0001688417],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9772171,0.007199097,0.01462524,0.0004631241,0.00009447277,0.0003121855,0.00002636137,0.00001436687,0.00004802909],"genre_scores_gemma":[0.9967977,0.001159165,0.001321612,0.0001729994,0.0001136922,0.0001014131,0.0001425863,0.00001654945,0.0001742882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07327801,"threshold_uncertainty_score":0.3634126,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W2935753526","doi":"10.1038/s41392-019-0042-0","title":"Signal-induced PARP1-Erk synergism mediates IEG expression","year":2019,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"Université de Montréal","funders":"National Institute on Drug Abuse; Efficacy and Mechanism Evaluation Programme","keywords":"MAPK/ERK pathway; PARP1; Cell biology; Mechanism (biology); Intracellular; Stimulation; Signal transduction; Immediate early gene; Biology; Phosphorylation; Neuroscience; Gene expression; Chemistry; Gene; Genetics; Polymerase","retraction":null,"screen_n_in":null,"score":{"opus":0.09188745218005683,"gpt":0.3504766878720647,"spread":0.2585892356920078,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004242404,0.0009568494,0.002500929,0.0005499021,0.0002132625,0.00006762131,0.0002060678,0.0009253409,0.006037366],"category_scores_gemma":[0.000008309838,0.0007211367,0.0009024615,0.0005911014,0.0001643157,0.0002153484,0.00001440826,0.001118906,0.0001790042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001679805,"about_ca_system_score_gemma":0.0004700599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001534476,"about_ca_topic_score_gemma":6.694255e-7,"domain_scores_codex":[0.9961032,0.0004683355,0.001061237,0.001077171,0.0007080492,0.0005820513],"domain_scores_gemma":[0.9981583,0.0002369689,0.0004822481,0.0005603725,0.0001689339,0.0003931868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005354045,0.0002945386,0.000005859663,0.005615461,0.0008226634,0.0000331542,0.0004248388,0.000002987337,0.03669033,0.00005779101,0.001234823,0.9542822],"study_design_scores_gemma":[0.00368079,0.0008382933,0.000009081919,0.009220435,0.0006030988,0.0002239389,0.00006540229,0.00001091178,0.01983293,0.0002407552,0.9644549,0.0008193869],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005985477,0.9941701,0.0004600259,0.0002595408,0.00129261,0.002271694,0.0001092588,0.0003149549,0.0005232561],"genre_scores_gemma":[0.002819439,0.9929655,0.0002645426,0.0004212946,0.001515302,0.0004236817,0.000613139,0.0002153366,0.0007617494],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9632202,"threshold_uncertainty_score":0.999524,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null},{"id":"W4401806042","doi":"10.1038/s41392-024-01930-0","title":"Annexin A1 binds PDZ and LIM domain 7 to inhibit adipogenesis and prevent obesity","year":2024,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false},"ca_institutions":"University of Windsor","funders":"Guangzhou Municipal Science and Technology Project; Peking University; National Natural Science Foundation of China","keywords":"Adipogenesis; Annexin A1; Adipocyte; Adipose tissue; Cell biology; Cancer research; Internal medicine; Biology; Endocrinology; Chemistry; Annexin; Medicine; Biochemistry; Apoptosis","retraction":null,"screen_n_in":null,"score":{"opus":0.00891411651861381,"gpt":0.235291345552783,"spread":0.2263772290341692,"validation_status":"score_only:v0-immature-baseline"},"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001690784,0.0001675129,0.0001259196,0.0000791063,0.0001194051,0.0000692914,0.00003998859,0.0001191761,0.0001145269],"category_scores_gemma":[0.000002209016,0.0001438862,0.00005233855,0.0001196791,0.0000715674,0.00001051241,0.00001647323,0.00007662219,0.000002635187],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005360889,"about_ca_system_score_gemma":0.00002539645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002111933,"about_ca_topic_score_gemma":0.00001487787,"domain_scores_codex":[0.9991381,0.00005973406,0.0001343308,0.0004152349,0.0000793103,0.0001733406],"domain_scores_gemma":[0.9997177,0.000006133447,0.00001516824,0.00009598483,0.00002488685,0.0001401574],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001796106,0.00006182873,0.0003584295,0.00003473924,0.00008340836,0.000004664525,0.0003725334,0.000005428948,0.9605979,0.0001836279,0.0001864549,0.03793135],"study_design_scores_gemma":[0.0007259633,0.001171095,0.004714499,0.00004973368,0.00002124509,0.00006184202,0.000215441,0.00004452268,0.8917628,0.001010858,0.09989469,0.0003273264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.976211,0.02041684,0.002032576,0.0007984834,0.0001166722,0.0002844502,0.00003606175,0.000031927,0.00007200937],"genre_scores_gemma":[0.9939249,0.004580025,0.0004748261,0.0003017462,0.0002454295,0.00003242067,0.00003253133,0.00002299429,0.0003850877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09970824,"threshold_uncertainty_score":0.5867508,"prediction_status":"machine_predicted_unvalidated"},"labels":[],"label_agreement":null}]}