{"id":"W1002711513","doi":"10.7150/jca.11709","title":"Genes Regulating Epithelial Polarity Are Critical Suppressors of Esophageal Oncogenesis","year":2015,"lang":"en","type":"review","venue":"Journal of Cancer","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Heart, Lung, and Blood Institute; American Heart Association","keywords":"Carcinogenesis; Esophageal cancer; Cancer research; Cancer; Polarity (international relations); Medicine; Cell polarity; Suppressor; Biology; Pathology; Internal medicine; Cell; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002016471,0.000542938,0.000703569,0.001373256,0.0001785125,0.0005494512,0.0004445403,0.0005413172,0.0021705],"category_scores_gemma":[0.0003073206,0.0001712715,0.0002733253,0.001215361,0.0002862948,0.0005540919,0.0003423103,0.000842913,0.001322936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004243214,"about_ca_system_score_gemma":0.000686108,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005563545,"about_ca_topic_score_gemma":0.001028304,"domain_scores_codex":[0.9999095,0.00001063462,0.00001459199,0.00001741088,0.00003586922,0.00001204823],"domain_scores_gemma":[0.9999119,0.00002659309,0.00001719289,0.000002765743,0.00003135459,0.00001019617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001139743,0.00004261733,0.000583015,0.01162759,0.00008383366,0.0004099455,0.00007901459,0.000339828,0.01385411,0.003981421,0.01844968,0.9504349],"study_design_scores_gemma":[0.00001573761,0.00006548696,0.001776115,0.001151499,0.0001080954,0.001788414,0.00005473476,0.00007114271,0.004056316,0.001227532,0.989668,0.00001687178],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006150589,0.9969099,0.0002358876,0.0002137978,0.0001742223,0.000005523636,0.00006029616,0.00001824726,0.001767027],"genre_scores_gemma":[0.002715251,0.9956259,0.0002390204,0.0001276506,0.00006932766,0.000006195682,0.0001064518,0.000002866309,0.001107346],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0021705,"threshold_uncertainty_score":0.007261038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05303382527208586,"score_gpt":0.3873715693174544,"score_spread":0.3343377440453685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}