{"id":"W10112001","doi":"10.1007/s11916-014-0474-8","title":"History and Present State of Targeted Intrathecal Drug Delivery","year":2015,"lang":"en","type":"review","venue":"Current Pain and Headache Reports","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"Regina General Hospital; University of Saskatchewan; Royal University Hospital","funders":"","keywords":"Pain medicine; Medicine; Chronic pain; Opioid; Intrathecal; Intensive care medicine; Pain control; Endogenous opioid; Anesthesia; Pharmacology; Receptor; Physical therapy; Anesthesiology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004972485,0.0004866971,0.0006905668,0.001614539,0.0002812355,0.000881203,0.0006224138,0.001169802,0.003875229],"category_scores_gemma":[0.001608004,0.0002206343,0.0004829082,0.001405986,0.0007183162,0.001400991,0.0005897352,0.001469689,0.0013388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004830903,"about_ca_system_score_gemma":0.0009343285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008042261,"about_ca_topic_score_gemma":0.001516939,"domain_scores_codex":[0.9997194,0.00004040294,0.00006038921,0.00006872142,0.00008227726,0.00002872242],"domain_scores_gemma":[0.9990684,0.0005087972,0.0002367411,0.0000357399,0.000106913,0.00004337907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002853302,0.0001068602,0.001342414,0.01752172,0.00013762,0.002917639,0.0002332534,0.0003569765,0.005991445,0.00603515,0.02741279,0.9376587],"study_design_scores_gemma":[0.00004198196,0.0002814138,0.003370013,0.007037874,0.000400376,0.03233211,0.0002082203,0.0002293617,0.00525949,0.003040527,0.9477363,0.00006233224],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009566785,0.9939103,0.0004691048,0.0007570534,0.0003037875,0.000007251142,0.00005617119,0.00001247991,0.003527132],"genre_scores_gemma":[0.009874656,0.9853614,0.0006306742,0.001358853,0.0009132116,0.00001403368,0.00008873145,0.000003753242,0.001754836],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003875229,"threshold_uncertainty_score":0.01296395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0799086512426122,"score_gpt":0.3443958478127714,"score_spread":0.2644871965701592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}