{"id":"W1017421949","doi":"","title":"Quaternary Ammonium β-Cyclodextrin Nanoparticles for Drug Delivery Across the Blood Retina/Brain Barriers","year":2008,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of New Brunswick","funders":"","keywords":"Cyclodextrin; Ammonium; Drug; Drug delivery; Retina; Chemistry; Pharmacology; Medicine; Neuroscience; Chromatography; Psychology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":["sts"],"category_scores_codex":[0.003752425,0.0004766371,0.0004933163,0.0001324774,0.003706577,0.00005189954,0.001528088,0.0002930898,0.0001604112],"category_scores_gemma":[0.001830639,0.0003761752,0.0001731236,0.001078533,0.01665426,0.0006812449,0.0005283882,0.0008866866,0.0001559208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001925047,"about_ca_system_score_gemma":0.000795285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002024018,"about_ca_topic_score_gemma":0.00001791535,"domain_scores_codex":[0.9946471,0.001271767,0.0007083355,0.001127176,0.0005114221,0.001734154],"domain_scores_gemma":[0.9953244,0.002385864,0.0004379548,0.0004726865,0.0004579931,0.0009210943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000430595,0.0001701978,0.08380084,0.00002345152,0.00009712217,0.000548044,0.009281991,0.0005927608,0.9030726,0.0002544508,0.001428436,0.0002994962],"study_design_scores_gemma":[0.001527217,0.0005646787,0.009573445,0.00002592955,0.00006711177,0.001642337,0.002266917,0.003710937,0.9721308,0.002226458,0.00573294,0.0005311638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929589,0.0005250744,0.000009829149,0.003030343,0.001595186,0.001232128,0.0001132867,0.0001385554,0.0003966884],"genre_scores_gemma":[0.994165,0.00003522275,0.0005557854,0.002675891,0.0002894138,0.0004145836,0.000009378082,0.00004313061,0.001811565],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07422739,"threshold_uncertainty_score":0.999869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1052402104038895,"score_gpt":0.433069999757817,"score_spread":0.3278297893539275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}