{"id":"W1034920215","doi":"10.1074/jbc.m114.598227","title":"Histidine 114 Is Critical for ATP Hydrolysis by the Universally Conserved ATPase YchF","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"Canadian Institutes of Health Research","keywords":"GTPase; Biology; Conserved sequence; ATPase; Amino acid; Biochemistry; ATP hydrolysis; Cell biology; Peptide sequence; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002117038,0.0002495497,0.0004179709,0.0001509134,0.0002886376,0.0004379203,0.0002904481,0.0004445666,0.0005597019],"category_scores_gemma":[0.0005120406,0.0001398534,0.0002860667,0.0002121809,0.0003756815,0.0004114092,0.0003223729,0.0004804424,0.0002238586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004162129,"about_ca_system_score_gemma":0.0004029565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001510851,"about_ca_topic_score_gemma":0.001012293,"domain_scores_codex":[0.999871,0.00002366577,0.00001166848,0.00001713379,0.00004543452,0.00003108321],"domain_scores_gemma":[0.999844,0.00004272706,0.00004068002,0.0000100354,0.00002576608,0.00003685819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005279132,0.00008904008,0.008348751,0.0001884188,0.00005224662,0.0008317907,0.0001104299,0.006146286,0.9730748,0.001880466,0.0001979046,0.008552035],"study_design_scores_gemma":[0.0001476394,0.0006057259,0.03172755,0.00004750345,0.00009942846,0.001531693,0.0003563496,0.04698028,0.9116034,0.001308452,0.005501775,0.00009010342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964037,0.000373253,0.002673648,0.00006688094,0.00001722113,0.000008243283,0.00005838218,0.00003060903,0.0003679316],"genre_scores_gemma":[0.9979222,0.0001505081,0.001580762,0.00001616509,0.00000526393,0.000004373792,0.0001520326,0.000009935419,0.0001588265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001510851,"threshold_uncertainty_score":0.003019869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02207438590266711,"score_gpt":0.2669993716268995,"score_spread":0.2449249857242324,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}