{"id":"W1040653919","doi":"10.1021/acs.jnatprod.5b00277","title":"Characterization of <scp>l</scp>-Digitoxosyl-phenanthroviridin from <i>Streptomyces venezuelae</i> ISP5230","year":2015,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Marine Biosciences; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; California HIV/AIDS Research Program","keywords":"Cytotoxicity; Streptomyces; Stereochemistry; Streptomycetaceae; Actinomycetales; Cancer cell lines; Chemistry; Tumor cells; Cell culture; Biochemistry; Biology; Bacteria; In vitro; Cancer cell; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005748251,0.0002590089,0.0007324957,0.0002190576,0.00004672323,0.0000455535,0.0002664049,0.0001563387,0.00001749703],"category_scores_gemma":[0.004072189,0.0001693699,0.0001849433,0.0005385718,0.0001378501,0.0006241279,0.00007105216,0.000556119,0.00002209647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001010135,"about_ca_system_score_gemma":0.0004147191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000240295,"about_ca_topic_score_gemma":0.000001659527,"domain_scores_codex":[0.9977382,0.00009142936,0.000869064,0.0003277185,0.0006805603,0.0002930033],"domain_scores_gemma":[0.9964088,0.0001239943,0.001150967,0.0003586586,0.001740289,0.0002172664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002702133,0.0002057113,0.00102434,0.0001035911,0.0001655345,0.00005893251,0.0003795427,0.000001121521,0.9723597,0.000009964865,0.02020337,0.005218],"study_design_scores_gemma":[0.001149337,0.0004419382,0.006641605,0.0003541595,0.0002106493,0.0003067,0.0001747803,0.000008446596,0.9328686,0.00007697024,0.05768044,0.00008635881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867765,0.004952798,0.000005282395,0.005238404,0.002475695,0.0002756787,0.00004351521,0.00002500183,0.0002070834],"genre_scores_gemma":[0.9936788,0.0004068861,0.001257467,0.0003396616,0.003018874,2.17627e-7,0.00006702002,0.00003007686,0.001200981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03949106,"threshold_uncertainty_score":0.6906702,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02116046596180253,"score_gpt":0.2481434647935344,"score_spread":0.2269829988317319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}