{"id":"W1040653919","doi":"10.1021/acs.jnatprod.5b00277","title":"Characterization of <scp>l</scp>-Digitoxosyl-phenanthroviridin from <i>Streptomyces venezuelae</i> ISP5230","year":2015,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Marine Biosciences; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; California HIV/AIDS Research Program","keywords":"Cytotoxicity; Streptomyces; Stereochemistry; Streptomycetaceae; Actinomycetales; Cancer cell lines; Chemistry; Tumor cells; Cell culture; Biochemistry; Biology; Bacteria; In vitro; Cancer cell; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007243191,0.0001901646,0.0001631592,0.0002047865,0.000113713,0.0002216249,0.0001116042,0.0001013884,0.0006559363],"category_scores_gemma":[0.0001538938,0.0000543733,0.0001226747,0.00033049,0.0001147586,0.0001147269,0.00008552174,0.0002185082,0.0001967116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001750525,"about_ca_system_score_gemma":0.0003142357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003034028,"about_ca_topic_score_gemma":0.003779794,"domain_scores_codex":[0.9999572,0.000008136306,0.000005058687,0.000009854323,0.00001154079,0.000008215327],"domain_scores_gemma":[0.999918,0.00001448677,0.00002019834,0.0000115313,0.00001743764,0.00001846111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007092451,0.00001373676,0.0004005576,0.00003290131,0.000002497354,0.00007985549,0.00001096497,0.00009418605,0.9973785,0.0000182185,0.00001184644,0.001885785],"study_design_scores_gemma":[0.00002689261,0.0009382672,0.03135911,0.00001741521,0.00003017401,0.0006798383,0.0001290673,0.0005427625,0.9610157,0.00004141957,0.005211082,0.000008268335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945511,0.0009577249,0.001336259,0.00004371538,0.000006392156,0.00004206369,0.00117796,0.00002110235,0.001863737],"genre_scores_gemma":[0.9929734,0.0006183769,0.002168401,0.00003298644,0.00000393068,0.00001498336,0.002896149,0.000010634,0.001281154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003034028,"threshold_uncertainty_score":0.006032705,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02116046596180253,"score_gpt":0.2481434647935344,"score_spread":0.2269829988317319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}