{"id":"W1040760625","doi":"10.1007/bf03256275","title":"Molecular-Targeted Therapy for Duchenne Muscular Dystrophy","year":2008,"lang":"en","type":"review","venue":"Molecular Diagnosis & Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Health Canada","funders":"","keywords":"Duchenne muscular dystrophy; Genetic enhancement; Muscular dystrophy; Medicine; Dystrophin; Gene delivery; Disease; Bioinformatics; Exon skipping; Zinc finger nuclease; Genome editing; Biology; Gene; Genetics; Internal medicine; Exon; CRISPR; Alternative splicing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000370722,0.0009105062,0.001342498,0.001159115,0.0002710352,0.0006476451,0.0008479712,0.000955727,0.002578962],"category_scores_gemma":[0.0002382199,0.000245805,0.0003585925,0.0009092136,0.0004604685,0.0007938512,0.0004465567,0.001573755,0.002031776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005511753,"about_ca_system_score_gemma":0.0004609726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007948944,"about_ca_topic_score_gemma":0.001738594,"domain_scores_codex":[0.9998995,0.00001656625,0.000009745105,0.00001719799,0.00004394355,0.00001296037],"domain_scores_gemma":[0.999943,0.00002563307,0.00001054782,0.00000279713,0.00001158927,0.000006488072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001499952,0.0001663662,0.00008450258,0.005287913,0.00007980373,0.0004914631,0.00004761474,0.0006314816,0.01273882,0.00527947,0.02743099,0.9476116],"study_design_scores_gemma":[0.00007345036,0.0001582546,0.0004344693,0.0007285977,0.00008425906,0.001782804,0.00002626116,0.0001677821,0.00320594,0.001491159,0.9918295,0.00001743715],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004909079,0.9952157,0.001061714,0.0002460811,0.0004220809,0.00001534111,0.00002110862,0.00002738401,0.002499777],"genre_scores_gemma":[0.003028563,0.9915259,0.001156935,0.0003061781,0.0001977353,0.00003166297,0.0000566587,0.00000484895,0.003691475],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002578962,"threshold_uncertainty_score":0.008627534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03652345605317493,"score_gpt":0.3386475188846578,"score_spread":0.3021240628314829,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}