{"id":"W1041490","doi":"10.1016/b978-0-12-394816-8.00006-4","title":"scyllo-Inositol, Preclinical, and Clinical Data for Alzheimer’s Disease","year":2012,"lang":"en","type":"review","venue":"Advances in pharmacology","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":83,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"In vivo; Pharmacology; Long-term potentiation; Bioavailability; In vitro; Pharmacokinetics; Clinical trial; Toxicity; Inositol; Alzheimer's disease; Chemistry; Medicine; Disease; Biology; Receptor; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008745588,0.0005082912,0.002335286,0.000196464,0.00009590048,0.00001573075,0.0005787467,0.0003437599,0.000196146],"category_scores_gemma":[0.0003175207,0.0003876131,0.0004078833,0.0002010401,0.0005960703,0.0004679292,0.0006851653,0.0007508186,0.0001021549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000681795,"about_ca_system_score_gemma":0.001027162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003193365,"about_ca_topic_score_gemma":0.000005784176,"domain_scores_codex":[0.9959406,0.0005798757,0.001200303,0.001199542,0.000250657,0.0008290755],"domain_scores_gemma":[0.9943922,0.002859225,0.0003738644,0.0009634121,0.00007629307,0.001334998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008448205,0.001826859,0.004597065,0.006464703,0.00884134,0.0002720206,0.000001907324,4.94266e-8,1.292703e-8,0.00002802832,0.004462143,0.9726611],"study_design_scores_gemma":[0.003325788,0.0003812003,0.0002272096,0.001559905,0.0408921,0.00003802526,0.000002161785,0.00004896554,2.097366e-7,0.00008975913,0.9531398,0.000294854],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001197226,0.9924952,0.00001123935,0.0002089192,0.001403989,0.004305662,0.001359818,0.00004823092,0.0001550167],"genre_scores_gemma":[0.0001775864,0.9928012,0.001129564,0.0003206617,0.001663199,0.0009761577,0.002820467,0.00008495935,0.00002613152],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9723662,"threshold_uncertainty_score":0.9998576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.344066319841501,"score_gpt":0.5958613766676677,"score_spread":0.2517950568261667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}