{"id":"W1054473502","doi":"10.1016/j.steroids.2015.08.001","title":"Molecular regulation of steroidogenesis in endocrine Leydig cells","year":2015,"lang":"en","type":"review","venue":"Steroids","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":191,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre hospitalier universitaire de Québec; Université Laval","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Leydig cell; Paracrine signalling; Biology; Hormone; Endocrinology; Internal medicine; Cell biology; Steroidogenic acute regulatory protein; Autocrine signalling; Transcription factor; Population; Cell signaling; Sexual differentiation; Endocrine system; Androgen; Signal transduction; Luteinizing hormone; Cell culture; Receptor; Gene expression; Genetics; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002204076,0.0002990202,0.001447151,0.0003903123,0.000008820189,0.000008087328,0.00009249407,0.000171032,0.00008230668],"category_scores_gemma":[0.00005547582,0.0002464666,0.0003025461,0.0004228023,0.00004070661,0.0000427481,0.00005342115,0.0001874995,0.00006736098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001783412,"about_ca_system_score_gemma":0.0002276931,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002978867,"about_ca_topic_score_gemma":0.000004691989,"domain_scores_codex":[0.9983053,0.0001214854,0.0006631089,0.0003372599,0.0003619394,0.000210873],"domain_scores_gemma":[0.998939,0.0000397893,0.0002574949,0.0005290149,0.0001297377,0.0001049784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002969825,0.0001268514,0.00008147282,0.0122997,0.000115976,0.0001396231,0.00003056334,0.000006012001,0.00109585,0.00004328616,0.0002580053,0.985773],"study_design_scores_gemma":[0.001204339,0.0003951297,0.0001658415,0.009870587,0.001541649,0.0002725287,0.00001480525,0.00002019052,0.001448586,0.0000456165,0.9847296,0.0002911379],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001758982,0.9950992,0.0001310239,0.0000100541,0.0003519549,0.0008663448,0.00001815672,0.00003242471,0.001731807],"genre_scores_gemma":[0.001521646,0.9966428,0.0004378066,0.00002489949,0.0001517872,0.0000551622,0.0002906281,0.0000763659,0.0007989279],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9854818,"threshold_uncertainty_score":0.9999987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05153975669703649,"score_gpt":0.326529601983386,"score_spread":0.2749898452863495,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}