{"id":"W105474233","doi":"10.1016/bs.pmbts.2014.11.006","title":"Translational Control of Chronic Pain","year":2015,"lang":"en","type":"review","venue":"Progress in molecular biology and translational science","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"PI3K/AKT/mTOR pathway; Neuroscience; Translation (biology); Nociception; Chronic pain; MAPK/ERK pathway; Neurotrophic factors; Biology; Central nervous system; Signal transduction; Medicine; Cell biology; Gene; Messenger RNA; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001248544,0.001167413,0.001547316,0.001823027,0.0003756613,0.001573577,0.0009769176,0.001404946,0.006211383],"category_scores_gemma":[0.001174085,0.0003459469,0.0005690392,0.00148578,0.001260819,0.002045855,0.001568756,0.002721929,0.002170605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007595066,"about_ca_system_score_gemma":0.002257237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006648838,"about_ca_topic_score_gemma":0.0011786,"domain_scores_codex":[0.9996808,0.0000662188,0.00004274576,0.00004947032,0.0001063133,0.00005445182],"domain_scores_gemma":[0.9995984,0.0001978608,0.00006021043,0.00001999326,0.00007991091,0.00004358122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001841345,0.00009726497,0.0001425945,0.01858448,0.0000976422,0.0002190598,0.00009042837,0.0003194528,0.003574864,0.01660667,0.03651625,0.9235671],"study_design_scores_gemma":[0.00004664987,0.0001007591,0.0005534911,0.003808754,0.0001170565,0.0005017226,0.00006986965,0.0001167489,0.0007550439,0.009855827,0.9840524,0.00002157906],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007056011,0.9977112,0.0002434072,0.0004655773,0.0004560399,0.000005868566,0.00001428947,0.000008587714,0.001024524],"genre_scores_gemma":[0.001122733,0.9970213,0.0002697642,0.0004228005,0.000551954,0.000009743669,0.00003135642,0.000001680175,0.0005687612],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006211383,"threshold_uncertainty_score":0.02077913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02804911988397038,"score_gpt":0.3875883653293507,"score_spread":0.3595392454453803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}