{"id":"W1062333943","doi":"10.1016/j.gene.2015.07.074","title":"Structure and function of cardiac troponin C (TNNC1): Implications for heart failure, cardiomyopathies, and troponin modulating drugs","year":2015,"lang":"en","type":"review","venue":"Gene","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":135,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Institute of General Medical Sciences; Division of Orthopaedic Surgery, University of Alberta; National Institutes of Health; University of Alberta; Elsevier Foundation; Heart and Stroke Foundation of Canada; Foundation for the National Institutes of Health","keywords":"Troponin; Troponin C; Cardiac muscle; Troponin I; Actin; Calcium; Biology; Myofilament; Muscle contraction; Skeletal muscle; Troponin complex; Biophysics; Internal medicine; Biochemistry; Anatomy; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004378951,0.0004152643,0.002708706,0.0002032557,0.0001692358,0.0000234012,0.0000528827,0.0003104729,0.000001926107],"category_scores_gemma":[0.0001055493,0.000339129,0.0005349615,0.0002641131,0.0001489732,0.00005140924,0.0001214498,0.0002432373,7.451747e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000109122,"about_ca_system_score_gemma":0.0002547405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002631437,"about_ca_topic_score_gemma":0.000002989895,"domain_scores_codex":[0.9983044,0.0001196068,0.0005486178,0.0005382429,0.000204268,0.0002848169],"domain_scores_gemma":[0.99864,0.0001320358,0.0002686992,0.0004923963,0.0003059217,0.0001609191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005340752,0.00001352486,0.0002183475,0.0105326,0.001014771,6.977801e-7,0.0002458889,0.000001316791,0.0005866893,0.0002423018,0.006104912,0.9809855],"study_design_scores_gemma":[0.0005928575,0.0002453403,0.001053756,0.001394195,0.005551749,0.0001805987,0.0002062048,0.000002251156,0.00009746318,0.0002138416,0.9901683,0.0002934274],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002211537,0.9937577,0.0002334991,0.0001158757,0.0003295734,0.001836029,0.001383659,0.00004417149,0.0000879776],"genre_scores_gemma":[0.004264534,0.9893092,0.004269743,0.00002754617,0.0009687015,0.0003043546,0.0006386464,0.00007921453,0.0001380704],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9840634,"threshold_uncertainty_score":0.9999061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03161925860297862,"score_gpt":0.3136484986270557,"score_spread":0.2820292400240771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}