{"id":"W1071546559","doi":"10.1053/j.gastro.2015.07.061","title":"Development and Validation of a Scoring System to Predict Outcomes of Patients With Primary Biliary Cirrhosis Receiving Ursodeoxycholic Acid Therapy","year":2015,"lang":"en","type":"review","venue":"Gastroenterology","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":436,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; University Health Network","funders":"Novartis; Innogenetics; Alberta Cancer Foundation; Canadian Institutes of Health Research; Intercept Pharmaceuticals; Meso Scale Diagnostics; Medical Research Council; Alberta Heritage Foundation for Medical Research; Ferring Pharmaceuticals; Canadian Liver Foundation; Ikaria; Janssen Pharmaceuticals; Gilead Sciences; Cilag; Medtronic; Takeda Pharmaceutical Company; AbbVie; Abbott Laboratories; Merck; GlaxoSmithKline; Stichting voor Lever- en Maag-Darm Onderzoek; Wellcome Trust; Roche; Astellas Pharma US","keywords":"Medicine; Hazard ratio; Ursodeoxycholic acid; Internal medicine; Confidence interval; Liver transplantation; Primary biliary cirrhosis; Gastroenterology; Proportional hazards model; Transplantation; Cohort; Population","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004204723,0.001004046,0.002644989,0.002357017,0.0002018217,0.001622742,0.001161799,0.0006593959,0.0008217519],"category_scores_gemma":[0.005354873,0.0002624232,0.001796477,0.002151244,0.0003666824,0.0008668549,0.0007352483,0.001184955,0.0003042099],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006170148,"about_ca_system_score_gemma":0.001909552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0025869,"about_ca_topic_score_gemma":0.003466425,"domain_scores_codex":[0.9985703,0.0004773444,0.0003432397,0.0001399633,0.0004002719,0.00006879008],"domain_scores_gemma":[0.9979491,0.000867303,0.0004052032,0.00004666577,0.0006817883,0.00005000536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0005424488,0.0002157179,0.03294019,0.01704857,0.003098146,0.0001384714,0.0001205925,0.0008555099,0.0009894674,0.001307689,0.00838646,0.9343567],"study_design_scores_gemma":[0.001589965,0.003787382,0.3634267,0.07143195,0.03780265,0.007273851,0.001708997,0.01472406,0.009006265,0.008154531,0.4803406,0.0007530939],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01185969,0.9833912,0.001961228,0.0006825859,0.0003330753,0.0001262247,0.0003739829,0.00002071754,0.001251317],"genre_scores_gemma":[0.0840432,0.8986342,0.0135975,0.0006542723,0.0004773691,0.0001890089,0.001610526,0.00001222546,0.0007816788],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004204723,"threshold_uncertainty_score":0.02223694,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03665530723577537,"score_gpt":0.2846474220221996,"score_spread":0.2479921147864242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}