{"id":"W109284734","doi":"10.3980/j.issn.2222-3959.2014.03.03","title":"Hypoxia increases adipogenesis and affects adipocytokine production in orbital fibroblasts-a possible explanation of the link between smoking and Graves' ophthalmopathy.","year":2014,"lang":"en","type":"article","venue":"PubMed","topic":"Ophthalmology and Eye Disorders","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre","funders":"","keywords":"Medicine; Adipogenesis; Leptin; Hypoxia (environmental); Endocrinology; Internal medicine; Graves' ophthalmopathy; Adipose tissue; Obesity; Disease; Graves' disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001364644,0.0001794972,0.0001572834,0.00020152,0.0002008258,0.0002022671,0.00009443442,0.0002117971,0.001260714],"category_scores_gemma":[0.0001818812,0.0001103503,0.0001909943,0.0001442819,0.0002116574,0.0001527817,0.0001945531,0.0001506257,0.0001161884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001760203,"about_ca_system_score_gemma":0.000110303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009932398,"about_ca_topic_score_gemma":0.0012565,"domain_scores_codex":[0.9999001,0.00002914479,0.000008842294,0.00001401728,0.00002105637,0.00002680084],"domain_scores_gemma":[0.999877,0.00003486631,0.00004132918,0.00001323517,0.00001201458,0.00002156742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001207246,0.00007339361,0.05270951,0.0001688875,0.00003789245,0.002070989,0.0002176764,0.00004399367,0.9391863,0.0001429286,0.0000898089,0.00405149],"study_design_scores_gemma":[0.00005123798,0.001603377,0.7937455,0.00005790906,0.0001321262,0.007266469,0.001071014,0.0004853269,0.1922659,0.0003406441,0.002966922,0.00001349948],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955468,0.002820254,0.0003652272,0.00008704056,0.00001980715,0.00001432279,0.0001177466,0.000004034102,0.001024706],"genre_scores_gemma":[0.9979499,0.001167857,0.000221263,0.00006009674,0.0000166409,0.00001310724,0.0001128584,0.000001315929,0.0004569644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001260714,"threshold_uncertainty_score":0.004217565,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01806436590440571,"score_gpt":0.231873304701311,"score_spread":0.2138089387969052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}