{"id":"W111241889","doi":"10.3233/ch-2008-1081","title":"The mechanism of nitrate-induced preconditioning","year":2008,"lang":"en","type":"article","venue":"Clinical Hemorheology and Microcirculation","topic":"Cardiac Ischemia and Reperfusion","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; Mount Sinai Hospital","funders":"Heart and Stroke Foundation of Canada","keywords":"Mitochondrial permeability transition pore; Ischemia; Nitric oxide; Chemistry; Pharmacology; Mitochondrion; Oxygen; Reactive oxygen species; Reperfusion injury; Endothelium; Ischemic preconditioning; Antioxidant; Mechanism (biology); Biophysics; Cell biology; Biochemistry; Medicine; Biology; Internal medicine; Apoptosis; Programmed cell death","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003402481,0.00006126572,0.000218591,0.00002119766,0.0002293955,0.000001868779,0.0000238309,0.0002085563,0.00002117346],"category_scores_gemma":[0.0001733994,0.00004172685,0.0001178542,0.00004986293,0.000257245,0.00002726012,0.000023143,0.0002082946,0.000008002172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007910432,"about_ca_system_score_gemma":0.00007334239,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005317916,"about_ca_topic_score_gemma":0.00000147208,"domain_scores_codex":[0.999276,0.00006528845,0.000349501,0.0001523234,0.00005702356,0.00009990407],"domain_scores_gemma":[0.9992789,0.0003402114,0.000111463,0.0001310009,0.00008793592,0.0000504657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003081737,0.0001223999,0.1855746,0.0000528228,0.0001214812,0.00001783923,0.0002645059,0.000001552493,0.7938493,0.009603217,0.0002871977,0.009796822],"study_design_scores_gemma":[0.003357988,0.0004769787,0.7002563,0.00008368868,0.0002215969,0.001936051,0.0001585827,0.0005050114,0.2872242,0.005036914,0.0005783518,0.0001643447],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965692,0.000335333,0.0006661738,0.0003801256,0.0002981798,0.0001535986,7.591235e-7,0.00001721627,0.001579386],"genre_scores_gemma":[0.9985924,0.0004858503,0.0002020065,0.0001726335,0.0001344119,0.00000428357,0.00002787204,0.000005640913,0.0003748769],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5146817,"threshold_uncertainty_score":0.1764348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04235342297821106,"score_gpt":0.3308081491732228,"score_spread":0.2884547261950117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}