{"id":"W111785244","doi":"10.1007/978-1-4939-1112-7_3","title":"START Domain Protein Structure and Ligand Specificity","year":2014,"lang":"en","type":"book-chapter","venue":"","topic":"Metabolomics and Mass Spectrometry Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Protein tertiary structure; Helix (gastropod); Ligand (biochemistry); Plant lipid transfer proteins; Biophysics; Protein structure; Mechanism (biology); Protein secondary structure; Chemistry; Protein domain; Conformational change; Biology; Cell biology; Biochemistry; Receptor; Physics; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001627674,0.0004918831,0.0003182276,0.0002576038,0.0002343089,0.0007643937,0.0005463082,0.0004268772,0.004012316],"category_scores_gemma":[0.0001320419,0.0002508608,0.0001873483,0.0004145379,0.0004573037,0.0006832923,0.000411675,0.0008172122,0.003026029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005984377,"about_ca_system_score_gemma":0.0002778063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006267958,"about_ca_topic_score_gemma":0.0008823381,"domain_scores_codex":[0.9999322,0.000006262008,0.000002291665,0.00001896516,0.00002880037,0.0000114843],"domain_scores_gemma":[0.9999737,0.00001084243,0.000002666059,0.000002957426,0.00000484962,0.00000498246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003213673,0.00007598998,0.0004366672,0.0006143003,0.00002086526,0.0003853254,0.000119264,0.001827886,0.6126827,0.154583,0.02189871,0.2070339],"study_design_scores_gemma":[0.0000116549,0.00007704901,0.003074188,0.00008608465,0.0000230182,0.00130072,0.0001111648,0.003595263,0.4626693,0.08100389,0.4480042,0.00004363377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.1508292,0.2441171,0.2057007,0.003551968,0.001705183,0.0001121254,0.002702085,0.001512239,0.3897694],"genre_scores_gemma":[0.3445734,0.103621,0.0654017,0.001384822,0.0004456638,0.0001911435,0.004691055,0.000510626,0.4791806],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004012316,"threshold_uncertainty_score":0.01342255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007775347364051624,"score_gpt":0.2016257836177771,"score_spread":0.1938504362537255,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}