{"id":"W1135359073","doi":"10.1021/acs.bioconjchem.5b00376","title":"Spheroid and Tissue Assembly via Click Chemistry in Microfluidic Flow","year":2015,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"3D Printing in Biomedical Research","field":"Engineering","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Microfluidics; Spheroid; Chemistry; Click chemistry; Tissue engineering; Cell; Nanotechnology; Biophysics; In vitro; Biomedical engineering; Combinatorial chemistry; Biochemistry; Biology; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004024303,0.0002333596,0.0002386786,0.00002255396,0.00002458952,0.00006008696,0.0003051908,0.0003173015,0.0002414637],"category_scores_gemma":[0.000209497,0.0002522534,0.00002979851,0.0002277795,0.0001581791,0.00006618738,0.0001686557,0.0004355329,0.0001241628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001760163,"about_ca_system_score_gemma":0.00007212743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004093223,"about_ca_topic_score_gemma":0.000001331094,"domain_scores_codex":[0.9985198,0.00001402987,0.0003057955,0.0003469382,0.0003018336,0.0005116218],"domain_scores_gemma":[0.9990546,0.00005372531,0.00002541419,0.0003575747,0.0000511071,0.0004576491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007039007,0.0000229435,0.0005793943,0.0004578679,0.00001431117,0.0000475475,0.00005974455,0.00001880949,0.9846155,4.770673e-7,0.005442504,0.00873386],"study_design_scores_gemma":[0.0006312078,0.000008470735,0.0001925021,0.00007252049,0.000004297263,0.00004461107,0.00005127549,0.00343006,0.9567577,0.00008390661,0.03845289,0.0002705066],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9824898,0.004595706,0.0004020362,0.0001572279,0.0001044821,0.000131304,0.00001152164,0.000239517,0.01186843],"genre_scores_gemma":[0.9970133,0.0004686086,0.0009471867,0.0000328284,0.0002740563,0.00003569977,0.00003881192,0.00006230026,0.001127209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03301039,"threshold_uncertainty_score":0.999993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01722172605422288,"score_gpt":0.2544341090688298,"score_spread":0.2372123830146069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}