{"id":"W1141070425","doi":"10.1016/j.semcancer.2015.08.004","title":"Alpha2beta1 integrin in cancer development and chemoresistance","year":2015,"lang":"en","type":"review","venue":"Seminars in Cancer Biology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Université Laval","keywords":"Integrin; Collagen receptor; Metastasis; Extracellular matrix; Cancer research; Angiogenesis; Cancer cell; Cancer; Biology; Cancer stem cell; Cell biology; Tumor microenvironment; Immunology; Stem cell; Receptor; Genetics; Tumor cells","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007478108,0.0004507893,0.00212674,0.0006123884,0.0000217039,0.000009156402,0.0002879699,0.0006505439,0.0002571265],"category_scores_gemma":[0.000146214,0.0003513472,0.00009637087,0.0007065666,0.0002595776,0.00002026415,0.00030861,0.001100759,0.00002634058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002360739,"about_ca_system_score_gemma":0.003200215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007355482,"about_ca_topic_score_gemma":0.003749774,"domain_scores_codex":[0.9973046,0.0002075213,0.0007813749,0.0008384224,0.0002346832,0.0006333844],"domain_scores_gemma":[0.9989457,0.0001690781,0.000194109,0.0003752656,0.0001016028,0.0002142793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007326895,0.00006761253,0.002418126,0.007420556,0.00005829283,0.0001800595,0.0001859919,2.075551e-7,0.00003725458,0.00001605434,0.002291824,0.9872507],"study_design_scores_gemma":[0.0006620387,0.00007522957,0.0002311047,0.02399562,0.00006713676,0.00004389684,0.00004223868,0.000003125705,0.0001214882,0.00002577048,0.9744145,0.000317844],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002041086,0.9952896,0.00000181993,0.0001923245,0.0002622395,0.0009976664,0.00003972548,0.00001654861,0.001159016],"genre_scores_gemma":[0.00005797486,0.9945955,0.0007416786,0.0001240407,0.0001320772,0.00115386,0.0001248542,0.0000600772,0.003009886],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9869329,"threshold_uncertainty_score":0.9998938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1166447348061009,"score_gpt":0.4612294767089271,"score_spread":0.3445847419028263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}