{"id":"W1152594321","doi":"10.1096/fasebj.29.1_supplement.728.13","title":"Epigenetic Regulation of RGS2 in Cystic Fibrosis","year":2015,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut de Readaptation Gingras Lindsay de Montreal","funders":"","keywords":"Regulator of G protein signaling; RGS2; Downregulation and upregulation; Gene knockdown; Cystic fibrosis transmembrane conductance regulator; Biology; Small hairpin RNA; Epigenetics; DNA methylation; Methylation; Immunology; Cell biology; Cancer research; Cystic fibrosis; Molecular biology; Gene expression; Gene; Genetics; Signal transduction; GTPase-activating protein; G protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008454626,0.0001595545,0.0001621058,0.0001899308,0.0001218686,0.0001487214,0.000093922,0.0002253512,0.0012657],"category_scores_gemma":[0.0001106824,0.00008049625,0.0002226994,0.00009575945,0.0001588343,0.00007526048,0.0001792731,0.0002319362,0.0002085575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001995059,"about_ca_system_score_gemma":0.0001163501,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008472371,"about_ca_topic_score_gemma":0.001650603,"domain_scores_codex":[0.9999163,0.00001190854,0.000005966045,0.00002804627,0.00002547517,0.00001221154],"domain_scores_gemma":[0.9999318,0.00001087466,0.00002734154,0.000008645714,0.00001071401,0.00001058812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006386772,0.000004818912,0.0009455266,0.000037409,0.000007319184,0.0001120635,0.00002007436,0.00004946501,0.9966664,0.00009235826,0.00006735142,0.001933233],"study_design_scores_gemma":[0.0000230288,0.0003787103,0.1409181,0.00003163693,0.00006804825,0.001356883,0.00007486607,0.001547488,0.8438881,0.0002013788,0.01149535,0.00001641377],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867443,0.005719959,0.00355871,0.0002199523,0.00007789888,0.00002885667,0.0009910587,0.0001360862,0.00252331],"genre_scores_gemma":[0.9940764,0.001307125,0.001109545,0.0001206826,0.00001395325,0.00002366758,0.0005915959,0.0000150994,0.002741903],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0012657,"threshold_uncertainty_score":0.004234195,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03268408228957049,"score_gpt":0.3132054745331853,"score_spread":0.2805213922436148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}