{"id":"W1154552747","doi":"","title":"Regulation of FOXC1 Levels by Post–Translational Modifications: Implications for Glaucoma Pathologies Through Alterations in FOXC1 Stability","year":2005,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Glaucoma; Translational research; Posttranslational modification; Medicine; Ophthalmology; Biology; Pathology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004484246,0.0003590547,0.0003016925,0.0004749575,0.0005549467,0.0006864474,0.0003242596,0.0004785529,0.002045882],"category_scores_gemma":[0.0004103424,0.0001790292,0.0003488212,0.0003116225,0.0006760755,0.0008429126,0.0003372165,0.0005817145,0.0002670086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009950086,"about_ca_system_score_gemma":0.0004665364,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0024281,"about_ca_topic_score_gemma":0.002714063,"domain_scores_codex":[0.9998627,0.00001460298,0.00001274718,0.00003934301,0.00002717474,0.0000434498],"domain_scores_gemma":[0.9996917,0.00003519989,0.0001036335,0.0000383989,0.00005423961,0.00007677323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004166528,0.00002808686,0.002349031,0.00003786549,0.00001796193,0.0001001413,0.0000495234,0.00008905451,0.9926351,0.001238116,0.0001362918,0.00290216],"study_design_scores_gemma":[0.00005279481,0.0001421085,0.0476866,0.00001250198,0.00004568117,0.0003805281,0.00009558164,0.001273237,0.9455661,0.001102771,0.003618936,0.00002319336],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853671,0.005453818,0.005015223,0.001144897,0.0001190286,0.00002544377,0.0004910852,0.0001155142,0.002268024],"genre_scores_gemma":[0.9944793,0.001151579,0.001929238,0.0001686251,0.00003598784,0.00002386914,0.000264154,0.00003907382,0.001908059],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0024281,"threshold_uncertainty_score":0.007219315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08064935871637786,"score_gpt":0.3640643155390605,"score_spread":0.2834149568226826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}