{"id":"W1155813199","doi":"","title":"Cross–Species Comparison of the Effects of the P23H Mutation on Rhodopsin Trafficking and Toxicity","year":2006,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Photoreceptor and optogenetics research","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Rhodopsin; Mutation; Toxicity; Chemistry; Biochemistry; Retinal; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007468751,0.0004942875,0.0005600124,0.0005993001,0.0004341576,0.0004256275,0.0003842477,0.0008800644,0.002138728],"category_scores_gemma":[0.001103414,0.0003007904,0.0006826616,0.0002778386,0.000485715,0.0006204956,0.0006050766,0.001168347,0.0003686181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006221685,"about_ca_system_score_gemma":0.000256321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002109207,"about_ca_topic_score_gemma":0.001875536,"domain_scores_codex":[0.9995203,0.0001175497,0.00007018345,0.0001192783,0.0000886156,0.00008409598],"domain_scores_gemma":[0.9990994,0.0003016014,0.00009948662,0.0001426361,0.0001920515,0.0001650038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007529797,0.00006495082,0.0001498533,0.00003520877,0.00003453149,0.0001241432,0.00004723565,0.00003939075,0.9978431,0.0001388028,0.00008473406,0.0006851371],"study_design_scores_gemma":[0.00004685846,0.001985715,0.008700327,0.00001625812,0.0001453652,0.0009563101,0.0001185871,0.0005086734,0.9852226,0.0001640515,0.002112665,0.00002256353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934677,0.001983673,0.00153144,0.0001259411,0.0001127143,0.00007687215,0.0005232311,0.00006967661,0.002108647],"genre_scores_gemma":[0.991273,0.001323258,0.001316972,0.0003256265,0.00003145661,0.0001275987,0.001174384,0.0001202886,0.004307529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002138728,"threshold_uncertainty_score":0.007154763,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06729477850315216,"score_gpt":0.390968888021537,"score_spread":0.3236741095183848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}