{"id":"W1173060124","doi":"10.1371/journal.pcbi.1004405","title":"Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers","year":2015,"lang":"en","type":"article","venue":"PLoS Computational Biology","topic":"Cancer, Stress, Anesthesia, and Immune Response","field":"Medicine","cited_by":167,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"National Institute of General Medical Sciences; National Institute of Mental Health; Canadian Institutes of Health Research; National Heart, Lung, and Blood Institute; Killam Trusts; National Institutes of Health; Michael Smith Health Research BC; CHDI Foundation","keywords":"Palmitoylation; Biology; Compendium; Proteomics; Neurodegeneration; Computational biology; Neuroscience; Gene; Bioinformatics; Disease; Genetics; Biochemistry; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007004519,0.00006613063,0.0001708311,0.00005620139,0.00003944825,0.000003462185,0.00004757259,0.00004610531,6.958708e-7],"category_scores_gemma":[0.0001192953,0.00004048487,0.00003669862,0.0001031565,0.0002145397,0.00003236257,0.00002362927,0.00004016737,1.00385e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005520601,"about_ca_system_score_gemma":0.0001943395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002394402,"about_ca_topic_score_gemma":0.00008905929,"domain_scores_codex":[0.9994295,0.00009667571,0.0001974321,0.0001113909,0.00008821516,0.00007680773],"domain_scores_gemma":[0.9994594,0.0002168469,0.0001530276,0.00006953162,0.00007191008,0.00002925521],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008862139,0.00007180114,0.9868033,0.0002790037,0.00005289964,2.230798e-7,0.001284142,0.002434274,0.002046518,0.001756133,0.00002523997,0.004360235],"study_design_scores_gemma":[0.001317958,0.0002354812,0.9776444,0.0001250612,0.0000591089,0.00001439574,0.00103385,0.01726323,0.0003456377,0.001794127,0.0001149514,0.00005175386],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968779,0.001612131,0.00008911813,0.0007796685,0.0000824143,0.0004788299,0.00005500042,0.000005739761,0.00001916524],"genre_scores_gemma":[0.9997124,0.0000248741,0.00008515826,0.00003065039,0.0000561197,0.00004145946,0.00003578725,0.000005372709,0.000008193111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01482895,"threshold_uncertainty_score":0.1650925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01257284557019118,"score_gpt":0.246064323498147,"score_spread":0.2334914779279558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}