{"id":"W117369760","doi":"10.1096/fasebj.21.5.a126","title":"Carbon monoxide (CO) liberated by CO‐releasing molecule (CORM‐3) interferes with up‐regulation of vascular pro‐adhesive phenotype in experimental model of sepsis","year":2007,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute","funders":"","keywords":"Sepsis; Umbilical vein; Chemistry; VCAM-1; Oxidative stress; Pharmacology; Cell adhesion molecule; Inflammation; In vitro; Immunology; Cell adhesion; Biochemistry; Medicine; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000224276,0.0004480556,0.0004703377,0.000220133,0.0001457316,0.0001879465,0.0002080223,0.0003375526,0.0008306935],"category_scores_gemma":[0.0001398307,0.0001101407,0.0003339976,0.0001520767,0.0002434166,0.0001461969,0.0002057838,0.0007895894,0.0001323567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001552094,"about_ca_system_score_gemma":0.0002133629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002950446,"about_ca_topic_score_gemma":0.0005454453,"domain_scores_codex":[0.999828,0.00004610228,0.00001643561,0.0000215699,0.00003658249,0.00005132101],"domain_scores_gemma":[0.9998885,0.00001401457,0.00003790869,0.00001274657,0.00001222404,0.00003449174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007608642,0.0001544219,0.0001237265,0.00009034327,0.00001148636,0.0000633885,0.00001140448,0.00004437961,0.997405,0.00002612214,0.00004721234,0.001261524],"study_design_scores_gemma":[0.0001021264,0.00300439,0.002593498,0.00001081937,0.00003168825,0.0001957927,0.00001776021,0.0003845934,0.9924482,0.00002520089,0.001180997,0.000004958134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992959,0.004306972,0.001617261,0.0002122374,0.00008598638,0.00004279085,0.0001791375,0.00007233836,0.0005243213],"genre_scores_gemma":[0.9945763,0.001874764,0.001961051,0.0001011553,0.00002948972,0.00007077153,0.0003164831,0.00001065858,0.001059208],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008306935,"threshold_uncertainty_score":0.002778888,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01397231139173502,"score_gpt":0.2543906255412824,"score_spread":0.2404183141495474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}