{"id":"W1177805479","doi":"10.1074/jbc.m115.656918","title":"Extended Synaptotagmin Interaction with the Fibroblast Growth Factor Receptor Depends on Receptor Conformation, Not Catalytic Activity","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec; Université Laval","funders":"","keywords":"Synaptotagmin 1; Chemistry; Receptor; Cell biology; Biophysics; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004299438,0.000254007,0.0002708799,0.00003783055,0.0000873853,0.00003999102,0.0004618196,0.0002936804,0.0001352093],"category_scores_gemma":[0.0008489414,0.0001380941,0.0001498317,0.0001338246,0.0002223671,0.00003119502,0.0001282561,0.0006125114,0.00003695634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001364988,"about_ca_system_score_gemma":0.0002099365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004941014,"about_ca_topic_score_gemma":0.000001535702,"domain_scores_codex":[0.9984789,0.0001284879,0.0003555274,0.0002668271,0.0004515555,0.0003186358],"domain_scores_gemma":[0.9983169,0.0001011503,0.0004691624,0.0002884643,0.0005428221,0.0002814553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002777716,0.0001363617,0.0003868509,0.00003317155,0.0001049539,0.000004925746,0.00004972178,0.00001933102,0.9879226,0.000003424889,0.00763644,0.0009244637],"study_design_scores_gemma":[0.000869065,0.001863717,0.002180359,0.00006618412,0.000008838579,0.0001635881,0.0002450145,0.00001622858,0.9873472,0.000007939369,0.007035275,0.0001966037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975728,0.00005174919,0.0003347147,0.001021021,0.00009903077,0.0001314873,0.00005323013,0.00001199728,0.0007239842],"genre_scores_gemma":[0.9988182,0.00005945176,0.00020417,0.0001197985,0.0004316656,0.00000916214,0.0000663277,0.0000183307,0.0002728634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001908651,"threshold_uncertainty_score":0.5631314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03436814745621509,"score_gpt":0.2827781244966842,"score_spread":0.2484099770404691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}