{"id":"W1191344064","doi":"10.1016/j.mce.2015.08.018","title":"Tumor suppression by MEG3 lncRNA in a human pituitary tumor derived cell line","year":2015,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institutes of Health; Jarislowsky Foundation; National Institute of Diabetes and Digestive and Kidney Diseases; Massachusetts General Hospital","keywords":"MEG3; Pituitary tumors; Gene silencing; Cancer research; Biology; Epigenetics; Cell culture; Suppressor; Tumor suppressor gene; Gene expression; Gene; RNA; Long non-coding RNA; Carcinogenesis; Endocrinology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002289366,0.0003944119,0.0003962634,0.0002088879,0.0001010016,0.00003898139,0.0004136128,0.0002212881,0.00004912387],"category_scores_gemma":[0.0000801086,0.0004177718,0.0001289297,0.0001963043,0.0002021929,0.00000941597,0.0005717902,0.0004696758,0.00002096894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006182343,"about_ca_system_score_gemma":0.0001632909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002593564,"about_ca_topic_score_gemma":0.00005097117,"domain_scores_codex":[0.9970403,0.0003585547,0.0004200239,0.0009212823,0.000333178,0.0009266366],"domain_scores_gemma":[0.9987292,0.00001034256,0.0001078993,0.0006581875,0.0001197649,0.0003746204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001676244,0.0001902097,0.00008310524,0.00003577642,0.00004126413,0.001203692,0.00004897674,0.0001461178,0.9955559,0.0001252282,0.0020109,0.0003911411],"study_design_scores_gemma":[0.003142728,0.0009039249,0.00002155207,0.00001932222,0.00003066929,0.0002235365,0.0001455532,0.0001732943,0.9768292,0.000391127,0.0176881,0.0004310389],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9677234,0.01178502,0.01798868,0.0002320371,0.0001845979,0.0005096475,0.00002867277,0.00003713853,0.001510854],"genre_scores_gemma":[0.9975325,0.0001403931,0.0004633106,0.000646553,0.0000864029,0.0001061598,0.0004283527,0.00008679868,0.0005095571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02980911,"threshold_uncertainty_score":0.9998274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01105300307993731,"score_gpt":0.2556951566119358,"score_spread":0.2446421535319985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}