{"id":"W119760174","doi":"10.1007/978-94-007-7359-2_13","title":"Carbonic Anhydrase IX (CAIX) as a Mediator of Hypoxia-Induced Stress Response in Cancer Cells","year":2013,"lang":"en","type":"review","venue":"Sub-cellular biochemistry/Subcellular biochemistry","topic":"Enzyme function and inhibition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Mediator; Cancer cell; Cancer research; Cancer; Biology; Cancer stem cell; Downregulation and upregulation; Metastasis; Cell biology; Stem cell; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001013223,0.00210192,0.00274498,0.0004101376,0.0001608024,0.0001266767,0.001571589,0.003722386,0.0005214954],"category_scores_gemma":[0.000650949,0.002190761,0.001721738,0.001080185,0.0005280886,0.00002324622,0.0007170982,0.001445918,0.0001589954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006122144,"about_ca_system_score_gemma":0.003171877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002506913,"about_ca_topic_score_gemma":0.00001832638,"domain_scores_codex":[0.9915158,0.0005813134,0.002519866,0.002832854,0.001053768,0.001496452],"domain_scores_gemma":[0.9937723,0.0001449582,0.001805358,0.002981604,0.0004850504,0.0008107245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000393356,0.0006936021,0.000008682468,0.01055833,0.0003850815,0.000129302,0.00002530343,0.00000830717,0.9758043,0.000001531879,0.002916389,0.009075789],"study_design_scores_gemma":[0.001421631,0.0003300984,3.728482e-7,0.005064764,0.0005170055,0.00007187568,0.0001220001,0.00001742554,0.8962297,0.000006338745,0.09432893,0.001889855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.3940426,0.6032454,0.00002297902,0.00002911574,0.0004785733,0.001020718,0.000746321,0.00005952051,0.0003548114],"genre_scores_gemma":[0.1285169,0.8581902,0.0001123221,0.00007769724,0.001292482,0.0009606828,0.00663461,0.0004431513,0.00377195],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.2655257,"threshold_uncertainty_score":0.9991722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01783141655742459,"score_gpt":0.2774227740685375,"score_spread":0.2595913575111129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}