{"id":"W119769531","doi":"10.1016/s1063-5823(06)59011-8","title":"Lipid Stress at Play: Mechanosensitivity of Voltage-Gated Channels","year":2007,"lang":"en","type":"article","venue":"Current topics in membranes","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Mechanosensitive channels; Bilayer; Biophysics; Lipid bilayer; Chemistry; Ion channel; Transient receptor potential channel; Mechanotransduction; Nanotechnology; Neuroscience; Membrane; Biochemistry; Materials science; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027582,0.0001975172,0.0002530403,0.00009800147,0.0000472944,0.000008642533,0.0001852236,0.0001948996,0.00003345914],"category_scores_gemma":[0.00006782977,0.000182248,0.0001029272,0.000143016,0.00008499298,0.000005548188,0.0001508636,0.0001510444,0.000003625137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000216129,"about_ca_system_score_gemma":0.00003405573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002038478,"about_ca_topic_score_gemma":0.0002032528,"domain_scores_codex":[0.9987568,0.00004005427,0.0003358246,0.0003499275,0.0001877865,0.0003296002],"domain_scores_gemma":[0.9993573,0.00002156923,0.0001139695,0.0003446788,0.00008083413,0.00008163659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001024766,0.00013508,0.008928349,0.0002133465,0.00001555362,0.00001100065,0.0001733979,0.00003897537,0.9752703,0.0001346234,0.00009569108,0.01488115],"study_design_scores_gemma":[0.0005805558,0.00007059582,0.004364375,0.00005493961,0.0000190606,0.00001103853,0.00004624173,0.00001336679,0.9706997,0.0000248659,0.02391533,0.0001999622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965494,0.0004781423,0.0002736797,0.00003521246,0.002043061,0.0002166227,0.00004342452,0.00001424224,0.000346167],"genre_scores_gemma":[0.9979476,0.0002730103,0.0000538148,0.00003406683,0.001003774,0.000004274259,0.0001910542,0.00001747959,0.0004749813],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02381964,"threshold_uncertainty_score":0.7431859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01746743684653674,"score_gpt":0.2860049824507064,"score_spread":0.2685375456041697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}