{"id":"W1212923657","doi":"10.1016/j.bbalip.2015.08.008","title":"Regulation of hepatic cardiolipin metabolism by TNFα: Implication in cancer cachexia","year":2015,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Canadian Institutes of Health Research; Ministère de l'Enseignement Supérieur et de la Recherche; Ligue Contre le Cancer; Agence Nationale de la Recherche; Heart and Stroke Foundation of Canada","keywords":"Cardiolipin; Cachexia; Mitochondrion; Endocrinology; Internal medicine; Downregulation and upregulation; Tumor necrosis factor alpha; Biology; Hepatocyte; Chemistry; Cancer; Medicine; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009593339,0.0002387772,0.000201603,0.0001660643,0.0001095576,0.0001939722,0.00007608035,0.0002154059,0.0005329499],"category_scores_gemma":[0.00008223067,0.0000950106,0.0001982435,0.0001388585,0.0001654774,0.0001181418,0.0001102804,0.0002964827,0.0001084259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002786998,"about_ca_system_score_gemma":0.000116684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005183297,"about_ca_topic_score_gemma":0.0005936516,"domain_scores_codex":[0.9999419,0.0000149345,0.00000574414,0.000009417726,0.00001089624,0.00001715014],"domain_scores_gemma":[0.9999138,0.000008150366,0.00003745823,0.000006996661,0.00001214278,0.00002142126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001235985,0.00004485869,0.003539959,0.00007960275,0.00001452232,0.0002280771,0.00003425719,0.0000644495,0.9923413,0.0000378097,0.00003611837,0.002343088],"study_design_scores_gemma":[0.0001350398,0.002629166,0.1589806,0.00003425966,0.0001218778,0.001438527,0.0002701416,0.001351792,0.8320436,0.0001843923,0.002797497,0.0000130122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932075,0.005468116,0.0006131515,0.0001333103,0.00001894944,0.00001458407,0.0001338423,0.00002149995,0.0003890823],"genre_scores_gemma":[0.9973657,0.001584694,0.0002705526,0.00003266007,0.000007732498,0.00001404047,0.0001172062,0.000002199006,0.0006052888],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005329499,"threshold_uncertainty_score":0.002022088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01145063468644426,"score_gpt":0.2588535217295146,"score_spread":0.2474028870430704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}