{"id":"W1214817574","doi":"10.1593/neo.08580","title":"The Cytoplasmic Domain of proEGF Negatively Regulates Motility and Elastinolytic Activity in Thyroid Carcinoma Cells","year":2008,"lang":"en","type":"article","venue":"Neoplasia","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Research Manitoba","funders":"Deutsche Krebshilfe","keywords":"Motility; Cell biology; Epidermal growth factor; Biology; Transmembrane protein; Receptor; Cancer research; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001629736,0.0001374699,0.0001497722,0.00002621779,0.0001228203,0.000007799526,0.0001206681,0.0001200059,0.000001746237],"category_scores_gemma":[0.00004420779,0.0001050785,0.00004836054,0.00007624861,0.0002026969,0.000004868651,0.00009701807,0.0001126198,0.000002315253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001470097,"about_ca_system_score_gemma":0.00009070604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004449593,"about_ca_topic_score_gemma":0.00007402922,"domain_scores_codex":[0.9991198,0.00009820727,0.0001708412,0.0002781631,0.0001105667,0.0002224042],"domain_scores_gemma":[0.9995134,0.00003618637,0.00009346766,0.0002677408,0.00003590243,0.00005327455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001571448,0.0001072809,0.008752879,0.00001670323,0.0000104124,0.000007419577,0.0001172463,0.000003976546,0.9902053,0.00005278041,0.0001363062,0.000432568],"study_design_scores_gemma":[0.001005865,0.0002910868,0.04271399,0.00001032974,0.000004360859,0.0000390248,0.00004043025,0.0001220505,0.9549333,0.0005085756,0.0002416098,0.00008931856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986732,0.0004176987,0.00008655139,0.00005257334,0.00006054117,0.0002913124,0.00001323706,0.000006235004,0.0003986442],"genre_scores_gemma":[0.9993906,0.00009435083,0.0002480794,0.00002080851,0.00004783743,0.00002149305,0.000003518373,0.00001153671,0.0001617983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03527192,"threshold_uncertainty_score":0.4284978,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007059825808470761,"score_gpt":0.1975290399159542,"score_spread":0.1904692141074835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}