{"id":"W1216419228","doi":"10.1593/neo.09622","title":"Co-overexpression of Met and Hepatocyte Growth Factor Promotes Systemic Metastasis in NCI-H460 Non-Small Cell Lung Carcinoma Cells","year":2009,"lang":"en","type":"article","venue":"Neoplasia","topic":"Liver physiology and pathology","field":"Medicine","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research","keywords":"Hepatocyte growth factor; Autocrine signalling; Paracrine signalling; Cancer research; C-Met; Metastasis; Receptor tyrosine kinase; Hepatocyte Growth Factor Receptor; Tyrosine kinase; Biology; Medicine; Internal medicine; Cancer; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002386452,0.0003242466,0.0003862244,0.0001765457,0.0001611515,0.0003183769,0.000147588,0.000182381,0.001078323],"category_scores_gemma":[0.0001324403,0.0001634834,0.0002357644,0.0002144726,0.0001781909,0.0001792322,0.0001991205,0.0004735685,0.0005448841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002990159,"about_ca_system_score_gemma":0.0003005556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001946853,"about_ca_topic_score_gemma":0.003517169,"domain_scores_codex":[0.9997721,0.00004938367,0.00001812857,0.00002856181,0.0000823173,0.00004940855],"domain_scores_gemma":[0.9998555,0.00003834861,0.00001983309,0.00002701179,0.00001379884,0.00004547084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001436756,0.0001140015,0.0003591427,0.00003023643,0.000006494824,0.00009432341,0.00002262277,0.00008974501,0.9977925,0.00009799351,0.0001193139,0.001129863],"study_design_scores_gemma":[0.00005378733,0.001415323,0.007168868,0.000004595668,0.00001929205,0.0005743444,0.0000417736,0.003168729,0.9852802,0.00003104549,0.002236928,0.000005166985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995259,0.001360439,0.001279278,0.00009603604,0.00003722047,0.00002571675,0.0001795644,0.00007166078,0.001691001],"genre_scores_gemma":[0.9951957,0.000471764,0.00130977,0.00002686745,0.00001197557,0.00002287396,0.000283018,0.000009953772,0.002667989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001946853,"threshold_uncertainty_score":0.003871083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01248681625391685,"score_gpt":0.2438796441769149,"score_spread":0.231392827922998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}