{"id":"W1223753880","doi":"10.1016/j.bbagen.2015.07.006","title":"The Leishmania donovani peroxin 14 binding domain accommodates a high degeneracy in the pentapeptide motifs present on peroxin 5","year":2015,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - General Subjects","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Fonds Québécois de la Recherche sur la Nature et les Technologies; Canadian HIV Trials Network, Canadian Institutes of Health Research","keywords":"Biology; Biochemistry; Binding site; Biogenesis; Pentapeptide repeat; Organelle; Docking (animal); Computational biology; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002755283,0.0002591424,0.000401722,0.0001691504,0.0004199863,0.0003863756,0.0003378863,0.0005550634,0.00238065],"category_scores_gemma":[0.0003381259,0.0001953176,0.0002701356,0.0001394612,0.0003529717,0.0003242856,0.0004721133,0.0007245544,0.001044876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002119557,"about_ca_system_score_gemma":0.0002356844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002646917,"about_ca_topic_score_gemma":0.0003594836,"domain_scores_codex":[0.9998705,0.00003417418,0.00001157403,0.00003691256,0.00002260305,0.00002414378],"domain_scores_gemma":[0.9997467,0.00005481566,0.00005721456,0.00003295531,0.00003096211,0.00007726548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006422888,0.00005319824,0.001738018,0.0001277873,0.00003672264,0.0008442985,0.00007456861,0.0004862498,0.9865877,0.001967894,0.0003247771,0.007116527],"study_design_scores_gemma":[0.0001674537,0.001213047,0.02585705,0.00007744401,0.0001534099,0.006324688,0.0003350417,0.007452769,0.9292219,0.003096583,0.02602523,0.00007534603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810394,0.0006511139,0.0152127,0.0002608187,0.00009204784,0.00003064233,0.0001982377,0.0001281458,0.002386935],"genre_scores_gemma":[0.9914703,0.0001497866,0.006416347,0.0001991976,0.00001708829,0.00001417008,0.0003009109,0.0000169572,0.00141523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00238065,"threshold_uncertainty_score":0.007964015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03989574710285748,"score_gpt":0.3098296288127906,"score_spread":0.2699338817099331,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}