{"id":"W1227418196","doi":"10.3791/51207","title":"Assessing the Innate Sensing of HIV-1 Infected CD4<sup>+</sup> T Cells by Plasmacytoid Dendritic Cells Using an <em>Ex vivo</em> Co-culture System.","year":2015,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Ex vivo; Peripheral blood mononuclear cell; Biology; Immunology; T cell; Flow cytometry; Dendritic cell; Cell culture; Molecular biology; Cell biology; In vitro; Antigen; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003857932,0.0004755865,0.0003552079,0.000196664,0.0001672842,0.0004204734,0.0003264616,0.000476729,0.001548006],"category_scores_gemma":[0.0001479861,0.0001620608,0.0002537646,0.0002596653,0.0001487712,0.000261291,0.0002541545,0.001014038,0.0008503445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001898774,"about_ca_system_score_gemma":0.0001701566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002851613,"about_ca_topic_score_gemma":0.0004090702,"domain_scores_codex":[0.9995524,0.0001225815,0.00005568293,0.00008159757,0.0001251459,0.00006260433],"domain_scores_gemma":[0.9998283,0.00004758775,0.00003227693,0.00003803028,0.0000308808,0.00002280193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009195231,0.00004273448,0.0001789136,0.00003569231,0.000003140679,0.00002654021,0.00001756369,0.00007865563,0.9985825,0.00003917828,0.00004101857,0.0008622417],"study_design_scores_gemma":[0.00001373796,0.0003662422,0.001523847,0.000004642768,0.00001193603,0.0001544875,0.00002200615,0.001415721,0.9952878,0.00003001602,0.001164524,0.000004924238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9606863,0.001625246,0.03059877,0.0001870856,0.00008499745,0.0002205215,0.002285621,0.0002202575,0.00409123],"genre_scores_gemma":[0.9435052,0.001270725,0.04486879,0.0001553021,0.00003853655,0.0004964367,0.003233629,0.00006713218,0.006364136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001548006,"threshold_uncertainty_score":0.005178571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02838881124171943,"score_gpt":0.3553475690327669,"score_spread":0.3269587577910474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}