{"id":"W122755776","doi":"10.1007/978-1-59745-060-7_18","title":"Bone Marrow-Derived Mesenchymal Stem Cells: Isolation, Expansion, Characterization, Viral Transduction, and Production of Conditioned Medium","year":2008,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":290,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Mesenchymal stem cell; Cell biology; Clinical uses of mesenchymal stem cells; Paracrine signalling; Bone marrow; Biology; Stem cell transplantation for articular cartilage repair; Cell sorting; Stem cell; Immunology; Adult stem cell; Endothelial stem cell; In vitro; Flow cytometry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004368346,0.0009420683,0.0007283755,0.001250523,0.0004146344,0.000676692,0.0005092997,0.0005140557,0.001950947],"category_scores_gemma":[0.0002554464,0.0004521167,0.0005350526,0.001291864,0.0003014007,0.0003403808,0.0004777384,0.001088495,0.004214651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003306119,"about_ca_system_score_gemma":0.0008323808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006491826,"about_ca_topic_score_gemma":0.0010659,"domain_scores_codex":[0.9994331,0.00003747369,0.0000700879,0.00006993467,0.0003405671,0.00004883191],"domain_scores_gemma":[0.9999145,0.00001543307,0.00001690422,0.000009698367,0.00002577311,0.00001763895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000565212,0.00007776099,0.0003059053,0.0005317614,0.00001137963,0.0001471558,0.00005783078,0.0002822133,0.9632929,0.0006847247,0.0008007861,0.03375105],"study_design_scores_gemma":[0.00003478066,0.0003021509,0.002965163,0.0001369275,0.00005812345,0.0008983107,0.00004391415,0.0009422938,0.8865576,0.0005242722,0.1075016,0.00003489305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.2103653,0.1180986,0.5954705,0.001187821,0.001263815,0.009340701,0.0228943,0.005273383,0.03610553],"genre_scores_gemma":[0.3181343,0.129085,0.4526588,0.001293924,0.0005652574,0.008531193,0.05150158,0.0009393491,0.03729045],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.001950947,"threshold_uncertainty_score":0.006526589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03470971677383803,"score_gpt":0.3549415168397398,"score_spread":0.3202318000659018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}