{"id":"W122868440","doi":"10.1007/978-1-4615-0067-4_49","title":"XIAP Protects Photoreceptors from N-Methyl-N-Nitrosourea-Induced Retinal Degeneration","year":2003,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario","funders":"","keywords":"Retinitis pigmentosa; Retinal degeneration; Programmed cell death; XIAP; Photoreceptor cell; Apoptosis; Retina; Biology; Macular degeneration; Retinal; Degeneration (medical); Mutation; Cell biology; Neuroscience; Medicine; Genetics; Pathology; Caspase; Ophthalmology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002683203,0.0004195185,0.000457047,0.0005866258,0.0003399408,0.0003587332,0.0005120285,0.000592684,0.002141667],"category_scores_gemma":[0.0003492439,0.0003080366,0.0003432913,0.0002306703,0.0003556517,0.000408291,0.0002868962,0.001009888,0.0003152045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000483428,"about_ca_system_score_gemma":0.0005403815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002132537,"about_ca_topic_score_gemma":0.001747691,"domain_scores_codex":[0.9998363,0.00002563649,0.00002036395,0.00002838028,0.00003411212,0.00005513989],"domain_scores_gemma":[0.999751,0.00004564273,0.00004506978,0.00007059664,0.00002216539,0.00006546098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00075492,0.00008179615,0.0003059586,0.00005693245,0.00003076572,0.0001405437,0.00002808112,0.00008959132,0.9959754,0.0002191778,0.0001089315,0.00220791],"study_design_scores_gemma":[0.0001083664,0.0007929365,0.005583866,0.00001644646,0.00004615169,0.0003596572,0.00006656125,0.0007902317,0.9904783,0.0001833746,0.001565032,0.000009022306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951912,0.002073427,0.0009044757,0.0001729872,0.00005958168,0.00002239159,0.0001833123,0.0001786868,0.001213965],"genre_scores_gemma":[0.9959697,0.0008143985,0.0005225155,0.00004726654,0.0000121822,0.00002070582,0.0002233609,0.00001632421,0.002373603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002141667,"threshold_uncertainty_score":0.007164538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01911385163429625,"score_gpt":0.3206738690240462,"score_spread":0.30156001738975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}