{"id":"W1234396245","doi":"10.1385/0-89603-178-0:237","title":"Application of the Firefly Luciferase Reporter Gene","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"bioluminescence and chemiluminescence research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Reporter gene; Biology; Promoter; Transactivation; Gene; Molecular biology; DNA-binding domain; Bioreporter; Luciferase; Response element; Fusion gene; Therapeutic gene modulation; Gene expression; Transcription factor; Transfection; Genetics; Regulator gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00190668,0.001849853,0.001980753,0.001502092,0.0006217835,0.001059134,0.001694757,0.001780215,0.005037791],"category_scores_gemma":[0.0006818651,0.0007923598,0.001819861,0.001094442,0.0009198714,0.0007827205,0.001246196,0.003254389,0.004062751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008549429,"about_ca_system_score_gemma":0.001231707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008314759,"about_ca_topic_score_gemma":0.0008526077,"domain_scores_codex":[0.9980307,0.0004104653,0.000171258,0.0005495543,0.000651894,0.000186216],"domain_scores_gemma":[0.9995566,0.0001398017,0.00006398124,0.00007963384,0.00007988569,0.00008007952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006621533,0.0001083185,0.0001004573,0.0002843304,0.00001870488,0.00005227166,0.00003003679,0.00008265756,0.994232,0.0005174988,0.0005363839,0.00397099],"study_design_scores_gemma":[0.00003624067,0.0003806745,0.0005280789,0.00003465464,0.00004439368,0.0002822689,0.00002214617,0.001184442,0.9752897,0.0001611103,0.02200814,0.00002804246],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.131418,0.01328376,0.8174282,0.001534938,0.002094055,0.0029215,0.006099368,0.005440389,0.0197797],"genre_scores_gemma":[0.2880431,0.01428663,0.6321405,0.00154467,0.0002740334,0.004301448,0.01794198,0.0009501282,0.04051754],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.005037791,"threshold_uncertainty_score":0.01685309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02698884090451418,"score_gpt":0.2786227291082002,"score_spread":0.251633888203686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}