{"id":"W1261262105","doi":"10.1021/acs.jafc.5b03462","title":"<i>Ganoderma atrum</i> Polysaccharide Ameliorates Hyperglycemia-Induced Endothelial Cell Death via a Mitochondria-ROS Pathway","year":2015,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Fungal Biology and Applications","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"","keywords":"Reactive oxygen species; Mitochondrial permeability transition pore; Mitochondrion; Oxidative stress; Apoptosis; Mitochondrial ROS; Cytochrome c; MPTP; Umbilical vein; Cell biology; Biology; Chemistry; Pharmacology; Programmed cell death; Biochemistry; Endocrinology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007254689,0.0001847498,0.0003266699,0.00001785486,0.0000749442,0.00002287647,0.0001148434,0.0002019771,0.00001761307],"category_scores_gemma":[0.00004208304,0.0001027258,0.000139623,0.000112281,0.00004294393,0.00009454464,0.00003705274,0.0004200937,0.0000100592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004479901,"about_ca_system_score_gemma":0.0001058862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005181092,"about_ca_topic_score_gemma":7.703342e-7,"domain_scores_codex":[0.9990758,0.00001405423,0.0003579303,0.0001630742,0.0001887836,0.0002003769],"domain_scores_gemma":[0.9989343,0.00003779547,0.0002749274,0.0001065126,0.0002789259,0.0003675388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001521113,0.0001266087,0.001479518,0.00004015478,0.00006178888,0.00001568416,0.0001129608,0.000001237879,0.996558,0.000004993855,0.001230465,0.0002164569],"study_design_scores_gemma":[0.001939329,0.0006077333,0.005181545,0.00005437187,0.0001252619,0.002944803,0.0005292393,0.000002377889,0.9873642,0.0001035562,0.0009933196,0.0001542557],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961072,0.001014643,0.000008445413,0.001399278,0.000123574,0.00009538919,0.00002509562,0.00001940715,0.001207034],"genre_scores_gemma":[0.9975111,0.00007713457,0.0004772909,0.0002189273,0.001002746,0.000005897711,0.00001592266,0.000007935184,0.0006830023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009193812,"threshold_uncertainty_score":0.4189038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01805971295573405,"score_gpt":0.2206133662341622,"score_spread":0.2025536532784281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}