{"id":"W1279083794","doi":"10.1593/neo.101186","title":"Metronomic S-1 Chemotherapy and Vandetanib: An Efficacious and Nontoxic Treatment for Hepatocellular Carcinoma","year":2011,"lang":"en","type":"article","venue":"Neoplasia","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Vandetanib; Medicine; Angiogenesis; Angiogenesis inhibitor; Vascular endothelial growth factor; Pharmacology; Internal medicine; Tyrosine-kinase inhibitor; Cancer research; Hepatocellular carcinoma; Sorafenib; Cancer; VEGF receptors","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001066478,0.0003022186,0.0004569722,0.0001127727,0.00011589,0.00002589538,0.00004718015,0.0001424202,0.00009415112],"category_scores_gemma":[0.000007169564,0.0002421969,0.000121601,0.00006489159,0.0000758024,0.00009032399,0.00001355515,0.00005973312,0.00001155201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009901841,"about_ca_system_score_gemma":0.00006403647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001983158,"about_ca_topic_score_gemma":0.00005951516,"domain_scores_codex":[0.9988563,0.00003493963,0.0002167056,0.0004752336,0.00009040498,0.0003264349],"domain_scores_gemma":[0.9992081,0.00005154387,0.00005982235,0.0003115442,0.00003668061,0.0003322931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007543159,0.0004035682,0.9484546,0.0000494902,0.0001938254,0.00008380618,0.001979068,1.433203e-8,0.003015527,0.0001197537,0.00002630262,0.04491979],"study_design_scores_gemma":[0.02853353,0.01751298,0.7610018,0.00005672373,0.001835947,0.0006484053,0.0006436589,0.01588799,0.1612648,0.0003748192,0.01134738,0.0008919715],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954312,0.00198725,0.0001965185,0.0001221179,0.00006169526,0.001382943,0.00001949961,0.00008248508,0.0007163344],"genre_scores_gemma":[0.9942281,0.000255886,0.004622247,0.000111886,0.0001081195,0.0001881653,0.00005685483,0.00005876836,0.0003700276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1874528,"threshold_uncertainty_score":0.9876503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08597654884486267,"score_gpt":0.2570688382110946,"score_spread":0.1710922893662319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}