{"id":"W1279083794","doi":"10.1593/neo.101186","title":"Metronomic S-1 Chemotherapy and Vandetanib: An Efficacious and Nontoxic Treatment for Hepatocellular Carcinoma","year":2011,"lang":"en","type":"article","venue":"Neoplasia","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Vandetanib; Medicine; Angiogenesis; Angiogenesis inhibitor; Vascular endothelial growth factor; Pharmacology; Internal medicine; Tyrosine-kinase inhibitor; Cancer research; Hepatocellular carcinoma; Sorafenib; Cancer; VEGF receptors","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001642063,0.0002507943,0.0002943902,0.0002734467,0.0001293044,0.0002087911,0.0001975838,0.0002080713,0.0009210487],"category_scores_gemma":[0.0000829124,0.00008364267,0.0002176768,0.0002196686,0.0002310753,0.0002269036,0.000128441,0.0003334227,0.0001289186],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003202714,"about_ca_system_score_gemma":0.0003781947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006299411,"about_ca_topic_score_gemma":0.00198865,"domain_scores_codex":[0.9998971,0.00002316096,0.000007858433,0.00001451375,0.00002804985,0.00002931886],"domain_scores_gemma":[0.9999589,0.000004523632,0.00001277636,0.000005126631,0.000004204715,0.00001455205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002197331,0.001056069,0.002535788,0.0002163668,0.00005721045,0.0001723433,0.00003165454,0.0006244447,0.9567893,0.0004534103,0.0005284363,0.03533758],"study_design_scores_gemma":[0.001449702,0.04369951,0.04732487,0.00004062511,0.0002235396,0.002621561,0.00008192041,0.003589081,0.8824128,0.0002581266,0.01826582,0.00003239386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907347,0.006789801,0.0008723392,0.0001833476,0.00004102513,0.00006510625,0.00007825002,0.00004004747,0.001195492],"genre_scores_gemma":[0.9966955,0.001646882,0.0006139507,0.0000392354,0.00002013774,0.00002989493,0.0001993846,0.000004262167,0.0007508138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009210487,"threshold_uncertainty_score":0.003081203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08597654884486267,"score_gpt":0.2570688382110946,"score_spread":0.1710922893662319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}