{"id":"W130307969","doi":"10.1007/978-3-7091-1192-5_7","title":"Randomised Trial of Clazosentan, an Endothelin Receptor Antagonist, in Patients with Aneurysmal Subarachnoid Hemorrhage Undergoing Surgical Clipping (CONSCIOUS-2)","year":2012,"lang":"en","type":"article","venue":"Acta neurochirurgica. Supplementum","topic":"Intracranial Aneurysms: Treatment and Complications","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Medicine; Endothelin receptor antagonist; Subarachnoid hemorrhage; Antagonist; Clipping (morphology); Receptor antagonist; Anesthesia; Endothelin receptor; Interventional radiology; Surgery; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001496031,0.001793174,0.004376245,0.0004234581,0.0005808641,0.001619661,0.001091702,0.002933101,0.00981343],"category_scores_gemma":[0.002939455,0.001188974,0.002896857,0.0005200804,0.001226057,0.001286315,0.0006089006,0.003411801,0.001454305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009437181,"about_ca_system_score_gemma":0.001563638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002667558,"about_ca_topic_score_gemma":0.00439939,"domain_scores_codex":[0.998909,0.0005549568,0.0001020398,0.000192523,0.00005929434,0.0001822245],"domain_scores_gemma":[0.9986205,0.00046193,0.0002384322,0.0001529127,0.00009106495,0.0004351046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.996067,0.0005736863,0.0002282365,0.0001519965,0.0005536801,0.00002398782,0.00001174018,0.00004196832,0.0005496021,0.00003318996,0.0001754234,0.001589462],"study_design_scores_gemma":[0.9861669,0.01221479,0.0008594587,0.00001169771,0.0003550561,0.00001195956,0.000009042151,0.00008005361,0.00005515169,0.00005250479,0.0001756898,0.000007795148],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798477,0.005820574,0.0007498625,0.001744971,0.004138126,0.00268375,0.001942171,0.0001061781,0.002966618],"genre_scores_gemma":[0.9800391,0.003924186,0.001176204,0.002312759,0.002018202,0.003044203,0.002114258,0.00002601333,0.005345114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00981343,"threshold_uncertainty_score":0.03282917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01374454400892291,"score_gpt":0.2558383938850223,"score_spread":0.2420938498760994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}