{"id":"W130587520","doi":"10.1096/fasebj.24.1_supplement.681.4","title":"The Search for Human Alpha‐Amylase Inhibitors as Therapeutics for Diabetes and Obesity","year":2010,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Natural Antidiabetic Agents Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Diabetes mellitus; Postprandial; Medicine; Enzyme; Drug discovery; Obesity; Disease; Alpha-amylase; Pharmacology; Bioinformatics; Chemistry; Biochemistry; Internal medicine; Endocrinology; Biology; Amylase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.001093372,0.0001281757,0.000182844,0.00003249508,0.001826114,0.00008968687,0.0001597611,0.00006015325,0.00001559907],"category_scores_gemma":[0.0001371582,0.00005677791,0.000127258,0.00005676924,0.0003632427,0.00004532574,0.0000677214,0.0005765705,0.000004390045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001893417,"about_ca_system_score_gemma":0.00005443333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003488515,"about_ca_topic_score_gemma":0.00001356648,"domain_scores_codex":[0.9990396,0.00004335786,0.0002012047,0.0001137387,0.0002306169,0.0003714638],"domain_scores_gemma":[0.9987816,0.0006238485,0.00008577922,0.0001737389,0.0002234076,0.0001116121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002562022,0.0001438365,0.06774681,0.00007801728,0.0007110723,0.000005704502,0.001292634,3.856147e-7,0.8989336,0.002115906,0.005389114,0.02332672],"study_design_scores_gemma":[0.003950933,0.001371313,0.04575349,0.00009785222,0.0007471209,0.0001638936,0.00139955,0.0002224086,0.9114659,0.01194798,0.02263693,0.000242564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859343,0.001046886,0.00003262534,0.01168885,0.0005126408,0.0006486943,0.0000106098,0.00001431242,0.0001111019],"genre_scores_gemma":[0.9962605,0.0001830377,0.00027309,0.0008391591,0.001010874,0.00002010656,0.000002718956,0.00001916336,0.001391323],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02308416,"threshold_uncertainty_score":0.9994734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02692352854420354,"score_gpt":0.316119759526467,"score_spread":0.2891962309822635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}