{"id":"W132231329","doi":"10.1016/s0006-2952(02)00852-3","title":"A glutamate-gated chloride channel subunit from Haemonchus contortus:","year":2002,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Helminth infection and control","field":"Veterinary","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Glutamate receptor; Haemonchus contortus; Chloride channel; Allosteric regulation; Protein subunit; Chemistry; Moxidectin; Ivermectin; MOX fuel; Biochemistry; Biology; Glutamic acid; Nematode; Stereochemistry; Pharmacology; Biophysics; Amino acid; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008627525,0.0001812718,0.0002001182,0.00009505828,0.0001786746,0.0001982067,0.0002957599,0.0003790229,0.0004631834],"category_scores_gemma":[0.0002161095,0.00007188651,0.0001341866,0.0001445589,0.0001636999,0.0002522651,0.0001455312,0.0003204989,0.0002168054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002980005,"about_ca_system_score_gemma":0.0002189638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002561993,"about_ca_topic_score_gemma":0.003019057,"domain_scores_codex":[0.9999566,0.000005017805,0.000004593062,0.000007356152,0.00001203776,0.0000142815],"domain_scores_gemma":[0.9999295,0.00001150083,0.00000884306,0.000005429773,0.00002249404,0.00002214351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005545823,0.00002384495,0.000673734,0.00006918723,0.000009822975,0.0003600949,0.00005115953,0.00008874053,0.9957995,0.0001435826,0.0001303383,0.002095384],"study_design_scores_gemma":[0.0001023454,0.001059459,0.07159182,0.00003391888,0.0001133726,0.004403623,0.0003647377,0.003477851,0.9118257,0.000314056,0.006690529,0.00002248445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963482,0.001070441,0.0009680246,0.0002304136,0.00004054298,0.00002187251,0.0001660831,0.0000150346,0.001139533],"genre_scores_gemma":[0.9948585,0.001001966,0.001027425,0.0001210958,0.00002080404,0.000009561287,0.0009971897,0.000009180648,0.001954371],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002561993,"threshold_uncertainty_score":0.005094171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0724931767741262,"score_gpt":0.3228684207187526,"score_spread":0.2503752439446264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}