{"id":"W137248159","doi":"10.1023/a:1026211620793","title":"A phase II study of topotecan in patients with anaplastic oligodendroglioma or anaplastic mixed oligoastrocytoma","year":2003,"lang":"en","type":"article","venue":"Investigational New Drugs","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University; McGill University; Baker Hughes (Canada); Ottawa Regional Cancer Foundation; Hôpital Notre-Dame","funders":"McGill University","keywords":"Oligodendroglioma; Topotecan; Medicine; Oncology; Cancer research; Internal medicine; Chemotherapy; Glioma; Astrocytoma","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001506955,0.002081889,0.003894897,0.0007914802,0.0006776821,0.001466597,0.001292818,0.001507371,0.002504216],"category_scores_gemma":[0.001150107,0.0007979327,0.002085501,0.000909662,0.001346984,0.001293391,0.0004185588,0.003905975,0.0007950227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001775122,"about_ca_system_score_gemma":0.002813957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004605363,"about_ca_topic_score_gemma":0.008698279,"domain_scores_codex":[0.9992841,0.0002926791,0.00002886051,0.0001234791,0.00005867919,0.0002121691],"domain_scores_gemma":[0.9990405,0.0001886625,0.00009543006,0.00007381666,0.00006140726,0.0005401168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8219419,0.04722642,0.01197724,0.0007711552,0.002966639,0.0007832159,0.000357066,0.003021065,0.03094972,0.0003947768,0.003778626,0.07583223],"study_design_scores_gemma":[0.6197398,0.3591697,0.01293505,0.00002471295,0.001263946,0.0005250128,0.0001218349,0.001140433,0.002617089,0.00021199,0.002201319,0.00004918438],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927448,0.002524649,0.0004388457,0.0004426057,0.0001825453,0.001123592,0.001005166,0.00007027191,0.00146755],"genre_scores_gemma":[0.9905614,0.002779578,0.0009535501,0.0006147148,0.0001913493,0.001225143,0.002267547,0.00004054809,0.001366192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004605363,"threshold_uncertainty_score":0.01287943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01656685719675038,"score_gpt":0.2629395205782845,"score_spread":0.2463726633815341,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}