{"id":"W140890592","doi":"10.1385/0-89603-178-0:109","title":"Manipulation of Adenovirus Vectors","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":760,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Biology; Virology; DNA; Transcription (linguistics); RNA; Serotype; Mastadenovirus; Computational biology; Genetics; Adenoviridae; Gene; Genetic enhancement","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001609285,0.00009713178,0.00009596939,0.00003950472,0.00004873014,0.00001078366,0.0001486909,0.00008430808,0.00004554184],"category_scores_gemma":[0.00002617794,0.00009829565,0.00005941957,0.00001226363,0.00007022254,0.000001348738,0.0000369645,0.00006070061,0.000004383622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008275041,"about_ca_system_score_gemma":0.00003613568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003686467,"about_ca_topic_score_gemma":0.00009094564,"domain_scores_codex":[0.9992071,0.0001027674,0.0001533263,0.0002033611,0.0001549246,0.0001785538],"domain_scores_gemma":[0.9994604,0.000006228459,0.00005796964,0.0003673855,0.00006111529,0.00004690579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004656384,0.00004779702,0.000129104,0.00003649748,0.00008862879,0.00000278222,0.0001216168,0.0001530299,0.9837538,0.004882231,0.000654577,0.009664275],"study_design_scores_gemma":[0.0003908038,0.0005940102,0.0002239588,0.000005446661,0.000008815874,0.000002047834,0.000009668992,0.00001311207,0.9541217,0.0001677512,0.04435435,0.0001083488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9487134,0.002918988,0.000178556,0.00000235479,0.00007040528,0.0002118166,0.0000057114,0.00001213475,0.04788659],"genre_scores_gemma":[0.9966176,0.00007872366,0.00008196772,0.00003737702,0.00006333765,0.00001983662,0.00001559316,0.00002296117,0.003062643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04790412,"threshold_uncertainty_score":0.400838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06752512191773838,"score_gpt":0.3184505191735036,"score_spread":0.2509253972557652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}