{"id":"W141421893","doi":"10.1161/hyp.62.suppl_1.a248","title":"Abstract 248: Leptin-mediated Cardiovascular Disease Involves Aldosterone in Female Mice and Adolescent Women","year":2013,"lang":"en","type":"article","venue":"Hypertension","topic":"Hormonal Regulation and Hypertension","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Leptin; Endocrinology; Internal medicine; Aldosterone; Mineralocorticoid receptor; Leptin receptor; Medicine; Endothelial dysfunction; Blood pressure; Population; Blockade; Mineralocorticoid; Sympathetic nervous system; Obesity; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003243539,0.0009131617,0.0008519231,0.001204979,0.0005161407,0.0006906527,0.0005073838,0.0009207153,0.01391592],"category_scores_gemma":[0.0002164844,0.0006051355,0.0006446412,0.0003662219,0.0007833007,0.0006090553,0.0005781595,0.001964689,0.00236078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002915512,"about_ca_system_score_gemma":0.0002712143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005519618,"about_ca_topic_score_gemma":0.0006804613,"domain_scores_codex":[0.9994218,0.00007561938,0.0000458429,0.0001584226,0.0001535623,0.0001447568],"domain_scores_gemma":[0.9993554,0.00005286641,0.0001941871,0.00004490537,0.00003668371,0.0003160327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002365428,0.0005628599,0.002981485,0.00007314548,0.00002378063,0.0005359119,0.0001035234,0.00001751689,0.9889246,0.0002066433,0.0003978397,0.003807338],"study_design_scores_gemma":[0.001226347,0.006730426,0.3152796,0.0001822065,0.0002736885,0.009089177,0.0009109665,0.001024512,0.6492185,0.0006737833,0.01529893,0.00009191297],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884689,0.001303624,0.002987628,0.0007943834,0.0002623405,0.0001059671,0.002850784,0.0002499904,0.002976547],"genre_scores_gemma":[0.958524,0.001621789,0.004388473,0.0008599116,0.0002537984,0.0006772894,0.002866274,0.0003760039,0.03043245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01391592,"threshold_uncertainty_score":0.04655343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03146644144560604,"score_gpt":0.2211702674625784,"score_spread":0.1897038260169723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}