{"id":"W1415339541","doi":"10.1016/j.vph.2015.09.001","title":"Activation of endothelial IK Ca channels underlies NO-dependent myoendothelial feedback","year":2015,"lang":"en","type":"article","venue":"Vascular Pharmacology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary; University of Alberta; MacEwan University","funders":"Heart and Stroke Foundation of Canada","keywords":"Hyperpolarization (physics); Biophysics; Gap junction; Depolarization; Agonist; TRPC3; Biology; Chemistry; Neuroscience; Cell biology; Anatomy; Receptor; Transient receptor potential channel; Biochemistry; Intracellular; TRPC","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003316766,0.000217953,0.0003232534,0.0001792432,0.0001088961,0.00002201275,0.0003468536,0.0001414687,0.0007095668],"category_scores_gemma":[0.0001998855,0.0001880897,0.0001747842,0.0002174992,0.000212687,0.0001981391,0.0001343024,0.0002219752,0.0006745209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009550981,"about_ca_system_score_gemma":0.0001592612,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007746487,"about_ca_topic_score_gemma":0.000001537899,"domain_scores_codex":[0.9979527,0.000382369,0.0003307139,0.0004363808,0.0004810251,0.0004168121],"domain_scores_gemma":[0.9991775,0.00014596,0.0001843185,0.0001422096,0.000164936,0.0001850377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001741299,0.0002142689,0.00001059708,0.00002783371,0.0000445712,0.00001015509,0.0005576084,0.00261503,0.9900002,0.0003299184,0.005487075,0.000528554],"study_design_scores_gemma":[0.002755097,0.0002376612,0.000004230003,0.00000854372,0.00003991394,0.00001674292,0.000175582,0.001766749,0.9590079,0.0003198778,0.03547446,0.0001931888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806595,0.0000881086,0.001214524,0.000799648,0.01246932,0.0006939936,0.0000762452,0.0001273918,0.003871202],"genre_scores_gemma":[0.9958589,0.0002204565,0.00006883645,0.000711871,0.001368264,0.00004587441,0.000006886442,0.00003602574,0.001682889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03099231,"threshold_uncertainty_score":0.8669826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0500626179485766,"score_gpt":0.2960365067816162,"score_spread":0.2459738888330396,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}